Protein

MIA_04120_1

Length
166 amino acids


Browser: contig05:818046-818689+

Protein function

EGGNOG:0PKSRBNA1Catalyzes the oxidative ring opening of 3- hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate (By similarity)
SGD closest match:S000003786BNA13-hydroxyanthranilate 3,4-dioxygenase
CGD closest match:CAL0000184857BNA13-hydroxyanthranilate 3,4-dioxygenase

Protein alignments

%idAln lengthE-value
A0A0J9X944_GEOCN79.518%1662.96e-1043-hydroxyanthranilate 3,4-dioxygenase OS=Geotrichum candidum GN=BNA1 PE=3 SV=1
MCA_00060_180.723%1661.62e-103MCA_00060_1
A0A060T9I5_BLAAD70.303%1652.54e-933-hydroxyanthranilate 3,4-dioxygenase OS=Blastobotrys adeninivorans GN=BNA1 PE=3 SV=1
3HAO_YARLI70.659%1671.48e-903-hydroxyanthranilate 3,4-dioxygenase OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=BNA1 PE=3 SV=1
A0A1E3PNV5_9ASCO66.467%1676.91e-873-hydroxyanthranilate 3,4-dioxygenase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=BNA1 PE=3 SV=1
UniRef50_Q7SDX366.049%1627.40e-813-hydroxyanthranilate 3,4-dioxygenase n=87 Tax=Fungi TaxID=4751 RepID=3HAO_NEUCR
3HAO_CANAL65.244%1648.21e-843-hydroxyanthranilate 3,4-dioxygenase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=BNA1 PE=3 SV=1
A0A1E4TDE7_9ASCO60.119%1681.85e-773-hydroxyanthranilate 3,4-dioxygenase OS=Tortispora caseinolytica NRRL Y-17796 GN=BNA1 PE=3 SV=1
3HAO_YEAST60.870%1614.40e-713-hydroxyanthranilate 3,4-dioxygenase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=BNA1 PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0489

Protein family membership

Domains and repeats

  1. Domain
1 20 40 60 80 100 120 140 166

Detailed signature matches

    1. MF_00825 (3_HAO)
    2. PF06052 (3-HAO)
    1. SSF51182 (RmlC-like...)

Protein sequence

>MIA_04120_1
MLPDPINLPKWIAENKHLLKPPVNNFCIHRGGFTVMIVGGPNERTDYHVNQTPEWFHQLQGHMTLKVVDDGKFRDIEIGE
GEIFLLPPNTPHNPVRYANTIGLVVEQDRPTDLHDAIQWYCPECKELVYRKEFHMHDLGTQVKEAIEEFRSSEDSRTCKK
CGHVVN

GO term prediction

Biological Process

GO:0055114 oxidation-reduction process

Molecular Function

GO:0000334 3-hydroxyanthranilate 3,4-dioxygenase activity
GO:0005506 iron ion binding

Cellular Component

None predicted.