Protein
MCA_00060_1
Length
167 amino acids
Gene name: BNA1
Description: 3-hydroxyanthranilate 3,4-dioxygenase
Browser: contigA:151472-152122+
RNA-seq: read pairs 1468, FPKM 108.0, percentile rank 80.1% (100% = highest expression)
Protein function
| Annotation: | BNA1 | 3-hydroxyanthranilate 3,4-dioxygenase | |
|---|---|---|---|
| KEGG: | K00452 | HAAO | 3-hydroxyanthranilate 3,4-dioxygenase [EC:1.13.11.6] |
| EGGNOG: | 0PKSR | BNA1 | Catalyzes the oxidative ring opening of 3- hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate (By similarity) |
| SGD closest match: | S000003786 | BNA1 | 3-hydroxyanthranilate 3,4-dioxygenase |
| CGD closest match: | CAL0000184857 | BNA1 | 3-hydroxyanthranilate 3,4-dioxygenase |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MIA_04120_1 | 80.72% | 166 | 8e-102 | MIA_04120_1 |
| A0A0J9X944_GEOCN | 75.45% | 167 | 6e-98 | 3-hydroxyanthranilate 3,4-dioxygenase OS=Geotrichum candidum GN=BNA1 PE=3 SV=1 |
| 3HAO_YARLI | 68.05% | 169 | 6e-87 | 3-hydroxyanthranilate 3,4-dioxygenase OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=BNA1 PE=3 SV=1 |
| A0A1E3PNV5_9ASCO | 63.91% | 169 | 6e-84 | 3-hydroxyanthranilate 3,4-dioxygenase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=BNA1 PE=3 SV=1 |
| A0A060T9I5_BLAAD | 64.81% | 162 | 1e-82 | 3-hydroxyanthranilate 3,4-dioxygenase OS=Blastobotrys adeninivorans GN=BNA1 PE=3 SV=1 |
| 3HAO_CANAL | 64.42% | 163 | 9e-81 | 3-hydroxyanthranilate 3,4-dioxygenase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=BNA1 PE=3 SV=1 |
| UniRef50_Q7SDX3 | 61.45% | 166 | 2e-76 | 3-hydroxyanthranilate 3,4-dioxygenase n=87 Tax=Fungi TaxID=4751 RepID=3HAO_NEUCR |
| A0A1E4TDE7_9ASCO | 58.58% | 169 | 1e-75 | 3-hydroxyanthranilate 3,4-dioxygenase OS=Tortispora caseinolytica NRRL Y-17796 GN=BNA1 PE=3 SV=1 |
| 3HAO_YEAST | 60.12% | 163 | 2e-70 | 3-hydroxyanthranilate 3,4-dioxygenase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=BNA1 PE=1 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.0440
Protein family membership
- 3-hydroxyanthranilic acid dioxygenase (IPR010329)
Domains and repeats
-
Domain
1
20
40
60
80
100
120
140
167
Detailed signature matches
-
-
SSF51182 (RmlC-like...)
-
Protein sequence
>MCA_00060_1 MLPDPINLPKWIKENSDLLKPPVNNFCIHRGGFTVMIVGGPNERTDYHVNQTPEWFHQIKGKMTLRVVDDGTFRDIEIGE DEIFLLPANTPHNPVRYKDTIGLVVEQDRPEGLNDAIQWYCPNCKEVIYRREFYMSDLGTQVKQAIEEFRSNRENQKCSK CGTYVDA
GO term prediction
Biological Process
GO:0055114 oxidation-reduction process
Molecular Function
GO:0000334 3-hydroxyanthranilate 3,4-dioxygenase activity
GO:0005506 iron ion binding
Cellular Component
None predicted.