Protein

MIA_04094_1

Length
307 amino acids

Browser: contig05:736764-737688-

Protein function

EGGNOG:0PKJIFG06813.13-Hydroxybutyryl-CoA dehydrogenase

Protein alignments

%idAln lengthE-value
MCA_00033_185.570%2983.29e-176MCA_00033_1
A0A0J9X3N2_GEOCN76.221%3071.15e-159Uncharacterized protein OS=Geotrichum candidum GN=BN980_GECA01s11142g PE=4 SV=1
A0A167EM61_9ASCO65.461%3048.36e-136Uncharacterized protein OS=Sugiyamaella lignohabitans GN=AWJ20_5203 PE=4 SV=1
Q6CCJ7_YARLI66.447%3049.21e-134YALI0C08811p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_C08811g PE=4 SV=1
A0A1E3PL99_9ASCO64.356%3038.29e-129Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_82110 PE=4 SV=1
A0A1E4TCB2_9ASCO65.292%2911.27e-125Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_32659 PE=4 SV=1
A0A060T7G6_BLAAD60.544%2943.13e-1213-hydroxybutyryl-CoA dehydrogenase OS=Blastobotrys adeninivorans GN=ATPK2 PE=4 SV=1
UniRef50_B8MDV763.158%3047.87e-1173-hydroxybutyryl-CoA dehydrogenase, putative n=6 Tax=Dikarya TaxID=451864 RepID=B8MDV7_TALSN

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.9669
Predicted cleavage: 27

Protein family membership

Domains and repeats

  1. Domain
  2. Domain
  3. Domain
1 50 100 150 200 250 307

Detailed signature matches

  1. Family IPR022694
    3-hydroxyacyl-CoA dehydrogenase
    1. PIRSF000105 (HCDH)
  2. Domain IPR016040
    NAD(P)-binding domain
    1. SSF51735 (NAD(P)-bi...)
  3. Domain IPR006176
    3-hydroxyacyl-CoA dehydrogenase, NAD binding
    1. PF02737 (3HCDH_N)
  4. Domain IPR008927
    6-phosphogluconate dehydrogenase C-terminal domain-like
    1. SSF48179 (6-phospho...)
  5. Domain IPR013328
    6-phosphogluconate dehydrogenase, domain 2
    1. G3DSA:1.10.10...
  6. Domain IPR006108
    3-hydroxyacyl-CoA dehydrogenase, C-terminal
    1. PF00725 (3HCDH)
  7. SITE IPR006180
    3-hydroxyacyl-CoA dehydrogenase, conserved site
    1. PS00067 (3HCDH)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:3.40.50...

Protein sequence

>MIA_04094_1
MLRTSMTIQKRLFSSARTLAKDVNNLTVIGGGQMGLGIALVAANKAGVNVKLVDTSDAALEKGVAFMQKLLSKDIKKGRL
TEEQAKEVSARVTPTTDLTGALKDTDMVIEAVPEIPDLKFKIFSQLAKEAPADAILATNTSSISITKIAAAAKGAENRVV
AAHFMNPVPVQPGVEIIQALQTDKSVVDDTLAFVSRMGKVPSLAKDSPGFIANRILVPYINEAVIVLESGIGSAKDIDAM
MVNGCAMPMGPLALADFIGLDTCFAIMNVLYKDTGDSKYRPSVLLGKMVDAGWLGKKSGKGFYEYNK

GO term prediction

Biological Process

GO:0006631 fatty acid metabolic process
GO:0055114 oxidation-reduction process

Molecular Function

GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity
GO:0016491 oxidoreductase activity
GO:0070403 NAD+ binding

Cellular Component

None predicted.