Protein

MIA_04029_1

Length
593 amino acids

Browser: contig05:553613-555570+

Protein function

EGGNOG:0PGUMFRS1Phenylalanyl-tRNA synthetase, beta
SGD closest match:S000004050FRS1Phenylalanine--tRNA ligase beta subunit
CGD closest match:CAL0000190210FRS1Phenylalanine--tRNA ligase subunit beta

Protein alignments

%idAln lengthE-value
MCA_02250_183.165%5940.0MCA_02250_1
A0A0J9X6I0_GEOCN80.607%5930.0Similar to Saccharomyces cerevisiae YLR060W FRS1 Beta subunit of cytoplasmic phenylalanyl-tRNA synthetase OS=Geotrichum candidum GN=BN980_GECA03s07292g PE=4 SV=1
A0A167EGI9_9ASCO67.617%5960.0Phenylalanine--tRNA ligase subunit beta OS=Sugiyamaella lignohabitans GN=FRS1 PE=4 SV=1
A0A1E3PDS1_9ASCO67.327%6060.0Henylalanyl-tRNA synthetase beta chain (Phenylalanine--tRNA ligase beta chain) OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_53227 PE=4 SV=1
A0A060T2S1_BLAAD68.792%5960.0ARAD1C27456p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C27456g PE=4 SV=1
Q6C4X4_YARLI65.886%5980.0YALI0E22979p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E22979g PE=4 SV=1
A0A1D8PS16_CANAL65.657%5940.0Phenylalanine--tRNA ligase subunit beta OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=FRS1 PE=4 SV=1
UniRef50_O1343265.657%5940.0Phenylalanine--tRNA ligase beta subunit n=209 Tax=Eukaryota TaxID=2759 RepID=SYFB_CANAX
SYFB_YEAST59.532%5980.0Phenylalanine--tRNA ligase beta subunit OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=FRS1 PE=1 SV=3
A0A1E4TB98_9ASCO60.067%5960.0Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_133023 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.3000

Protein family membership

Domains and repeats

  1. Domain
1 100 200 300 400 500 593

Detailed signature matches

  1. Family IPR004531
    Phenylalanyl-tRNA synthetase, class IIc, beta subunit, archae/euk cytosolic
    1. TIGR00471
  2. Domain IPR009061
    Putative DNA-binding domain
    1. SSF46955 (Putative ...)
  3. Domain IPR005146
    B3/B4 tRNA-binding domain
    1. SM00873 (B3_4_2)
    2. PF03483 (B3_4)
  4. Domain IPR020825
    Phenylalanyl-tRNA synthetase, B3/B4
    1. SSF56037 (PheT/TilS...)
    2. G3DSA:3.50.40.10
  5. Domain IPR005147
    tRNA synthetase, B5-domain
    1. PF03484 (B5)
    2. SM00874 (B5_2)
    3. PS51483 (B5)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:3.30.56.10
  2. G3DSA:3.30.93...
  3. SSF55681 (Class II ...)
  4. cd00769 (PheRS_beta...)

Residue annotation

  1. dimer interface cd...
  2. motif 1 cd00769
  3. motif 3 cd00769
  4. motif 2 cd00769

Protein sequence

>MIA_04029_1
MPTISVDKEDLFKSLGREYTTKEFDELCFEFGIELDEDTSEGELQPGERPQLKIEIPANRYDMLCFEGISRALNIFLGRA
ELPVYKLTKPEELIQVTINPNTEQIRPYAASAVLRNITFDQKRYDSFIALQDKLHTNLCRNRSLVAIGTHDLDKIKGPIT
YEARKPEDIKFIPLNQTKEMNGHELMEFYEKDKNLGKYLHLIRDSPVYPAFYDADGHVLSLPPIINSDRTKITLNTKNVF
IDLTATDKTKLTIVVNQLVAMFSEYCEEAYTIEPVQINSDHNGQTRVEPVVANRETTAEISYINSCLGLDLKPEEICSLL
TKMSLLAKPSTSDKNLLDVSVPITRSDILHQCDIMEDAAIGYGYNNLKKTFPADSYTIAEALPINKISDIVRREVAQSGW
SEVMPLILCSHDENFAFLNRKDDGQTAVKLANPKTLEYQVVRTSLLPGILKTIRENRKHSLPIKVFESADVVFKNEKLER
KAFNRKHFAAVYAGQTSGFEIVHGLLDRVMAMLRVPWLETKAQQEAKTRGYWISPTDSATFFPGRGANVYFRAKDGAEAQ
VIGDLGIIHPDVMAKFEIPYVGSSLELNLEVFL

GO term prediction

Biological Process

GO:0006432 phenylalanyl-tRNA aminoacylation

Molecular Function

GO:0000166 nucleotide binding
GO:0000287 magnesium ion binding
GO:0003723 RNA binding
GO:0004826 phenylalanine-tRNA ligase activity
GO:0005524 ATP binding

Cellular Component

GO:0005737 cytoplasm