MIA_04020_1

Protein

Length

1,365 amino acids

Protein function

EGGNOG:	0PHZ4	FG06970.1	negative regulation of glycogen biosynthetic process
SGD closest match:	S000005405	PSK2	Serine/threonine-protein kinase PSK2
CGD closest match:	CAL0000200971	FUN31	Serine/threonine protein kinase

Protein alignments

	%id	Aln length	E-value
A0A0J9XJ98_GEOCN	81.419%	296	7.34e-172	Similar to Saccharomyces cerevisiae YOL045W PSK2 One of two (See also PSK1) PAS domain containing S/T protein kinases OS=Geotrichum candidum GN=BN980_GECA20s01363g PE=4 SV=1
UniRef50_A0A0J9XJ98	81.419%	296	1.50e-168	Similar to Saccharomyces cerevisiae YOL045W PSK2 One of two (See also PSK1) PAS domain containing S/T protein kinases n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XJ98_GEOCN
MCA_02218_1	79.125%	297	1.23e-165	MCA_02218_1
A0A167ECK2_9ASCO	72.325%	271	2.33e-136	Serine/threonine protein kinase PSK2 OS=Sugiyamaella lignohabitans GN=PSK2 PE=4 SV=1
A0A060TH49_BLAAD	69.521%	292	9.56e-137	ARAD1D35970p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D35970g PE=4 SV=1
Q6C310_YARLI	64.605%	291	6.86e-131	YALI0F03542p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F03542g PE=4 SV=1
A0A1E3PFS3_9ASCO	65.188%	293	1.43e-131	Pkinase-domain-containing protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_83733 PE=4 SV=1
A0A1D8PKQ6_CANAL	59.712%	278	3.84e-110	Serine/threonine protein kinase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=FUN31 PE=4 SV=1
A0A1E4TA86_9ASCO	61.049%	267	5.41e-119	Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_29437 PE=3 SV=1
PSK2_YEAST	59.028%	288	6.35e-105	Serine/threonine-protein kinase PSK2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PSK2 PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0362

Protein family membership

None predicted.

Domains and repeats

Domain
1,104 - 1,363
Protein kinase-like domain (IPR011009)
Protein kinase domain (IPR000719)

1 200 400 600 800 1000 1200 1365

Detailed signature matches

IPR011009

Protein kinase-like domain
1. SSF56112 (Protein k...)
  
  1,104 - 1,363
  
  SUPERFAMILY
  SSF56112 (Protein kinase-like (PK-like))
IPR000719

Protein kinase domain
1. PS50011 (PROTEIN_KI...)
  
  1,106 - 1,362
  
  PROSITE profiles
  PS50011 (PROTEIN_KINASE_DOM)
2. PF00069 (Pkinase)
  
  1,107 - 1,362
  
  Pfam
  PF00069 (Pkinase)
3. SM00220 (serkin_6)
  
  1,106 - 1,362
  
  SMART
  SM00220 (serkin_6)
IPR008271

Serine/threonine-protein kinase, active site
1. PS00108 (PROTEIN_KI...)
  
  1,236 - 1,248
  
  PROSITE patterns
  PS00108 (PROTEIN_KINASE_ST)

no IPR

Unintegrated signatures

G3DSA:1.10.51...

1,213 - 1,365

GENE3D
G3DSA:1.10.510.10 (G3DSA:1.10.510.10)
G3DSA:3.30.20...

1,096 - 1,212

GENE3D
G3DSA:3.30.200.20 (G3DSA:3.30.200.20)
G3DSA:3.30.45...

524 - 607

GENE3D
G3DSA:3.30.450.20 (G3DSA:3.30.450.20)

731 - 958

GENE3D
G3DSA:3.30.450.20 (G3DSA:3.30.450.20)
cd14004 (STKc_PASK)

1,105 - 1,362

CDD
cd14004 (STKc_PASK)
mobidb-lite (disord...)

818 - 884

MobiDB Lite
mobidb-lite (disorder_prediction)

355 - 375

MobiDB Lite
mobidb-lite (disorder_prediction)

414 - 437

MobiDB Lite
mobidb-lite (disorder_prediction)

1,009 - 1,068

MobiDB Lite
mobidb-lite (disorder_prediction)

1 - 133

MobiDB Lite
mobidb-lite (disorder_prediction)

Residue annotation

ATP binding site c...

1,112M

ATP binding site
1,112M, 1,113G, 1,120V, 1,134V, 1,136K, 1,176V, 1,192M, 1,193E, 1,194P, 1,195H, 1,199G, 1,201D, 1,244E, 1,245N, 1,247I, 1,257I, 1,258D
CDD
cd14004 (STKc_PASK)

1,113G

ATP binding site
1,112M, 1,113G, 1,120V, 1,134V, 1,136K, 1,176V, 1,192M, 1,193E, 1,194P, 1,195H, 1,199G, 1,201D, 1,244E, 1,245N, 1,247I, 1,257I, 1,258D
CDD
cd14004 (STKc_PASK)

1,120V

ATP binding site
1,112M, 1,113G, 1,120V, 1,134V, 1,136K, 1,176V, 1,192M, 1,193E, 1,194P, 1,195H, 1,199G, 1,201D, 1,244E, 1,245N, 1,247I, 1,257I, 1,258D
CDD
cd14004 (STKc_PASK)

1,134V

ATP binding site
1,112M, 1,113G, 1,120V, 1,134V, 1,136K, 1,176V, 1,192M, 1,193E, 1,194P, 1,195H, 1,199G, 1,201D, 1,244E, 1,245N, 1,247I, 1,257I, 1,258D
CDD
cd14004 (STKc_PASK)

1,136K

ATP binding site
1,112M, 1,113G, 1,120V, 1,134V, 1,136K, 1,176V, 1,192M, 1,193E, 1,194P, 1,195H, 1,199G, 1,201D, 1,244E, 1,245N, 1,247I, 1,257I, 1,258D
CDD
cd14004 (STKc_PASK)

1,176V

ATP binding site
1,112M, 1,113G, 1,120V, 1,134V, 1,136K, 1,176V, 1,192M, 1,193E, 1,194P, 1,195H, 1,199G, 1,201D, 1,244E, 1,245N, 1,247I, 1,257I, 1,258D
CDD
cd14004 (STKc_PASK)

1,192M

ATP binding site
1,112M, 1,113G, 1,120V, 1,134V, 1,136K, 1,176V, 1,192M, 1,193E, 1,194P, 1,195H, 1,199G, 1,201D, 1,244E, 1,245N, 1,247I, 1,257I, 1,258D
CDD
cd14004 (STKc_PASK)

1,193E

ATP binding site
1,112M, 1,113G, 1,120V, 1,134V, 1,136K, 1,176V, 1,192M, 1,193E, 1,194P, 1,195H, 1,199G, 1,201D, 1,244E, 1,245N, 1,247I, 1,257I, 1,258D
CDD
cd14004 (STKc_PASK)

1,194P

ATP binding site
1,112M, 1,113G, 1,120V, 1,134V, 1,136K, 1,176V, 1,192M, 1,193E, 1,194P, 1,195H, 1,199G, 1,201D, 1,244E, 1,245N, 1,247I, 1,257I, 1,258D
CDD
cd14004 (STKc_PASK)

1,195H

ATP binding site
1,112M, 1,113G, 1,120V, 1,134V, 1,136K, 1,176V, 1,192M, 1,193E, 1,194P, 1,195H, 1,199G, 1,201D, 1,244E, 1,245N, 1,247I, 1,257I, 1,258D
CDD
cd14004 (STKc_PASK)

1,199G

ATP binding site
1,112M, 1,113G, 1,120V, 1,134V, 1,136K, 1,176V, 1,192M, 1,193E, 1,194P, 1,195H, 1,199G, 1,201D, 1,244E, 1,245N, 1,247I, 1,257I, 1,258D
CDD
cd14004 (STKc_PASK)

1,201D

ATP binding site
1,112M, 1,113G, 1,120V, 1,134V, 1,136K, 1,176V, 1,192M, 1,193E, 1,194P, 1,195H, 1,199G, 1,201D, 1,244E, 1,245N, 1,247I, 1,257I, 1,258D
CDD
cd14004 (STKc_PASK)

1,244E

ATP binding site
1,112M, 1,113G, 1,120V, 1,134V, 1,136K, 1,176V, 1,192M, 1,193E, 1,194P, 1,195H, 1,199G, 1,201D, 1,244E, 1,245N, 1,247I, 1,257I, 1,258D
CDD
cd14004 (STKc_PASK)

1,245N

ATP binding site
1,112M, 1,113G, 1,120V, 1,134V, 1,136K, 1,176V, 1,192M, 1,193E, 1,194P, 1,195H, 1,199G, 1,201D, 1,244E, 1,245N, 1,247I, 1,257I, 1,258D
CDD
cd14004 (STKc_PASK)

1,247I

ATP binding site
1,112M, 1,113G, 1,120V, 1,134V, 1,136K, 1,176V, 1,192M, 1,193E, 1,194P, 1,195H, 1,199G, 1,201D, 1,244E, 1,245N, 1,247I, 1,257I, 1,258D
CDD
cd14004 (STKc_PASK)

1,257I

ATP binding site
1,112M, 1,113G, 1,120V, 1,134V, 1,136K, 1,176V, 1,192M, 1,193E, 1,194P, 1,195H, 1,199G, 1,201D, 1,244E, 1,245N, 1,247I, 1,257I, 1,258D
CDD
cd14004 (STKc_PASK)

1,258D

ATP binding site
1,112M, 1,113G, 1,120V, 1,134V, 1,136K, 1,176V, 1,192M, 1,193E, 1,194P, 1,195H, 1,199G, 1,201D, 1,244E, 1,245N, 1,247I, 1,257I, 1,258D
CDD
cd14004 (STKc_PASK)
active site cd14004

1,112M

active site
1,112M, 1,113G, 1,114E, 1,115G, 1,116A, 1,120V, 1,134V, 1,136K, 1,176V, 1,192M, 1,193E, 1,194P, 1,195H, 1,201D, 1,203F, 1,240D, 1,242K, 1,244E, 1,245N, 1,247I, 1,257I, 1,258D, 1,261S, 1,275G, 1,276T, 1,277L, 1,278D
CDD
cd14004 (STKc_PASK)

1,113G

active site
1,112M, 1,113G, 1,114E, 1,115G, 1,116A, 1,120V, 1,134V, 1,136K, 1,176V, 1,192M, 1,193E, 1,194P, 1,195H, 1,201D, 1,203F, 1,240D, 1,242K, 1,244E, 1,245N, 1,247I, 1,257I, 1,258D, 1,261S, 1,275G, 1,276T, 1,277L, 1,278D
CDD
cd14004 (STKc_PASK)

1,114E

active site
1,112M, 1,113G, 1,114E, 1,115G, 1,116A, 1,120V, 1,134V, 1,136K, 1,176V, 1,192M, 1,193E, 1,194P, 1,195H, 1,201D, 1,203F, 1,240D, 1,242K, 1,244E, 1,245N, 1,247I, 1,257I, 1,258D, 1,261S, 1,275G, 1,276T, 1,277L, 1,278D
CDD
cd14004 (STKc_PASK)

1,115G

active site
1,112M, 1,113G, 1,114E, 1,115G, 1,116A, 1,120V, 1,134V, 1,136K, 1,176V, 1,192M, 1,193E, 1,194P, 1,195H, 1,201D, 1,203F, 1,240D, 1,242K, 1,244E, 1,245N, 1,247I, 1,257I, 1,258D, 1,261S, 1,275G, 1,276T, 1,277L, 1,278D
CDD
cd14004 (STKc_PASK)

1,116A

active site
1,112M, 1,113G, 1,114E, 1,115G, 1,116A, 1,120V, 1,134V, 1,136K, 1,176V, 1,192M, 1,193E, 1,194P, 1,195H, 1,201D, 1,203F, 1,240D, 1,242K, 1,244E, 1,245N, 1,247I, 1,257I, 1,258D, 1,261S, 1,275G, 1,276T, 1,277L, 1,278D
CDD
cd14004 (STKc_PASK)

1,120V

active site
1,112M, 1,113G, 1,114E, 1,115G, 1,116A, 1,120V, 1,134V, 1,136K, 1,176V, 1,192M, 1,193E, 1,194P, 1,195H, 1,201D, 1,203F, 1,240D, 1,242K, 1,244E, 1,245N, 1,247I, 1,257I, 1,258D, 1,261S, 1,275G, 1,276T, 1,277L, 1,278D
CDD
cd14004 (STKc_PASK)

1,134V

active site
1,112M, 1,113G, 1,114E, 1,115G, 1,116A, 1,120V, 1,134V, 1,136K, 1,176V, 1,192M, 1,193E, 1,194P, 1,195H, 1,201D, 1,203F, 1,240D, 1,242K, 1,244E, 1,245N, 1,247I, 1,257I, 1,258D, 1,261S, 1,275G, 1,276T, 1,277L, 1,278D
CDD
cd14004 (STKc_PASK)

1,136K

active site
1,112M, 1,113G, 1,114E, 1,115G, 1,116A, 1,120V, 1,134V, 1,136K, 1,176V, 1,192M, 1,193E, 1,194P, 1,195H, 1,201D, 1,203F, 1,240D, 1,242K, 1,244E, 1,245N, 1,247I, 1,257I, 1,258D, 1,261S, 1,275G, 1,276T, 1,277L, 1,278D
CDD
cd14004 (STKc_PASK)

1,176V

active site
1,112M, 1,113G, 1,114E, 1,115G, 1,116A, 1,120V, 1,134V, 1,136K, 1,176V, 1,192M, 1,193E, 1,194P, 1,195H, 1,201D, 1,203F, 1,240D, 1,242K, 1,244E, 1,245N, 1,247I, 1,257I, 1,258D, 1,261S, 1,275G, 1,276T, 1,277L, 1,278D
CDD
cd14004 (STKc_PASK)

1,192M

active site
1,112M, 1,113G, 1,114E, 1,115G, 1,116A, 1,120V, 1,134V, 1,136K, 1,176V, 1,192M, 1,193E, 1,194P, 1,195H, 1,201D, 1,203F, 1,240D, 1,242K, 1,244E, 1,245N, 1,247I, 1,257I, 1,258D, 1,261S, 1,275G, 1,276T, 1,277L, 1,278D
CDD
cd14004 (STKc_PASK)

1,193E

active site
1,112M, 1,113G, 1,114E, 1,115G, 1,116A, 1,120V, 1,134V, 1,136K, 1,176V, 1,192M, 1,193E, 1,194P, 1,195H, 1,201D, 1,203F, 1,240D, 1,242K, 1,244E, 1,245N, 1,247I, 1,257I, 1,258D, 1,261S, 1,275G, 1,276T, 1,277L, 1,278D
CDD
cd14004 (STKc_PASK)

1,194P

active site
1,112M, 1,113G, 1,114E, 1,115G, 1,116A, 1,120V, 1,134V, 1,136K, 1,176V, 1,192M, 1,193E, 1,194P, 1,195H, 1,201D, 1,203F, 1,240D, 1,242K, 1,244E, 1,245N, 1,247I, 1,257I, 1,258D, 1,261S, 1,275G, 1,276T, 1,277L, 1,278D
CDD
cd14004 (STKc_PASK)

1,195H

active site
1,112M, 1,113G, 1,114E, 1,115G, 1,116A, 1,120V, 1,134V, 1,136K, 1,176V, 1,192M, 1,193E, 1,194P, 1,195H, 1,201D, 1,203F, 1,240D, 1,242K, 1,244E, 1,245N, 1,247I, 1,257I, 1,258D, 1,261S, 1,275G, 1,276T, 1,277L, 1,278D
CDD
cd14004 (STKc_PASK)

1,201D

active site
1,112M, 1,113G, 1,114E, 1,115G, 1,116A, 1,120V, 1,134V, 1,136K, 1,176V, 1,192M, 1,193E, 1,194P, 1,195H, 1,201D, 1,203F, 1,240D, 1,242K, 1,244E, 1,245N, 1,247I, 1,257I, 1,258D, 1,261S, 1,275G, 1,276T, 1,277L, 1,278D
CDD
cd14004 (STKc_PASK)

1,203F

active site
1,112M, 1,113G, 1,114E, 1,115G, 1,116A, 1,120V, 1,134V, 1,136K, 1,176V, 1,192M, 1,193E, 1,194P, 1,195H, 1,201D, 1,203F, 1,240D, 1,242K, 1,244E, 1,245N, 1,247I, 1,257I, 1,258D, 1,261S, 1,275G, 1,276T, 1,277L, 1,278D
CDD
cd14004 (STKc_PASK)

1,240D

active site
1,112M, 1,113G, 1,114E, 1,115G, 1,116A, 1,120V, 1,134V, 1,136K, 1,176V, 1,192M, 1,193E, 1,194P, 1,195H, 1,201D, 1,203F, 1,240D, 1,242K, 1,244E, 1,245N, 1,247I, 1,257I, 1,258D, 1,261S, 1,275G, 1,276T, 1,277L, 1,278D
CDD
cd14004 (STKc_PASK)

1,242K

active site
1,112M, 1,113G, 1,114E, 1,115G, 1,116A, 1,120V, 1,134V, 1,136K, 1,176V, 1,192M, 1,193E, 1,194P, 1,195H, 1,201D, 1,203F, 1,240D, 1,242K, 1,244E, 1,245N, 1,247I, 1,257I, 1,258D, 1,261S, 1,275G, 1,276T, 1,277L, 1,278D
CDD
cd14004 (STKc_PASK)

1,244E

active site
1,112M, 1,113G, 1,114E, 1,115G, 1,116A, 1,120V, 1,134V, 1,136K, 1,176V, 1,192M, 1,193E, 1,194P, 1,195H, 1,201D, 1,203F, 1,240D, 1,242K, 1,244E, 1,245N, 1,247I, 1,257I, 1,258D, 1,261S, 1,275G, 1,276T, 1,277L, 1,278D
CDD
cd14004 (STKc_PASK)

1,245N

active site
1,112M, 1,113G, 1,114E, 1,115G, 1,116A, 1,120V, 1,134V, 1,136K, 1,176V, 1,192M, 1,193E, 1,194P, 1,195H, 1,201D, 1,203F, 1,240D, 1,242K, 1,244E, 1,245N, 1,247I, 1,257I, 1,258D, 1,261S, 1,275G, 1,276T, 1,277L, 1,278D
CDD
cd14004 (STKc_PASK)

1,247I

active site
1,112M, 1,113G, 1,114E, 1,115G, 1,116A, 1,120V, 1,134V, 1,136K, 1,176V, 1,192M, 1,193E, 1,194P, 1,195H, 1,201D, 1,203F, 1,240D, 1,242K, 1,244E, 1,245N, 1,247I, 1,257I, 1,258D, 1,261S, 1,275G, 1,276T, 1,277L, 1,278D
CDD
cd14004 (STKc_PASK)

1,257I

active site
1,112M, 1,113G, 1,114E, 1,115G, 1,116A, 1,120V, 1,134V, 1,136K, 1,176V, 1,192M, 1,193E, 1,194P, 1,195H, 1,201D, 1,203F, 1,240D, 1,242K, 1,244E, 1,245N, 1,247I, 1,257I, 1,258D, 1,261S, 1,275G, 1,276T, 1,277L, 1,278D
CDD
cd14004 (STKc_PASK)

1,258D

active site
1,112M, 1,113G, 1,114E, 1,115G, 1,116A, 1,120V, 1,134V, 1,136K, 1,176V, 1,192M, 1,193E, 1,194P, 1,195H, 1,201D, 1,203F, 1,240D, 1,242K, 1,244E, 1,245N, 1,247I, 1,257I, 1,258D, 1,261S, 1,275G, 1,276T, 1,277L, 1,278D
CDD
cd14004 (STKc_PASK)

1,261S

active site
1,112M, 1,113G, 1,114E, 1,115G, 1,116A, 1,120V, 1,134V, 1,136K, 1,176V, 1,192M, 1,193E, 1,194P, 1,195H, 1,201D, 1,203F, 1,240D, 1,242K, 1,244E, 1,245N, 1,247I, 1,257I, 1,258D, 1,261S, 1,275G, 1,276T, 1,277L, 1,278D
CDD
cd14004 (STKc_PASK)

1,275G

active site
1,112M, 1,113G, 1,114E, 1,115G, 1,116A, 1,120V, 1,134V, 1,136K, 1,176V, 1,192M, 1,193E, 1,194P, 1,195H, 1,201D, 1,203F, 1,240D, 1,242K, 1,244E, 1,245N, 1,247I, 1,257I, 1,258D, 1,261S, 1,275G, 1,276T, 1,277L, 1,278D
CDD
cd14004 (STKc_PASK)

1,276T

active site
1,112M, 1,113G, 1,114E, 1,115G, 1,116A, 1,120V, 1,134V, 1,136K, 1,176V, 1,192M, 1,193E, 1,194P, 1,195H, 1,201D, 1,203F, 1,240D, 1,242K, 1,244E, 1,245N, 1,247I, 1,257I, 1,258D, 1,261S, 1,275G, 1,276T, 1,277L, 1,278D
CDD
cd14004 (STKc_PASK)

1,277L

active site
1,112M, 1,113G, 1,114E, 1,115G, 1,116A, 1,120V, 1,134V, 1,136K, 1,176V, 1,192M, 1,193E, 1,194P, 1,195H, 1,201D, 1,203F, 1,240D, 1,242K, 1,244E, 1,245N, 1,247I, 1,257I, 1,258D, 1,261S, 1,275G, 1,276T, 1,277L, 1,278D
CDD
cd14004 (STKc_PASK)

1,278D

active site
1,112M, 1,113G, 1,114E, 1,115G, 1,116A, 1,120V, 1,134V, 1,136K, 1,176V, 1,192M, 1,193E, 1,194P, 1,195H, 1,201D, 1,203F, 1,240D, 1,242K, 1,244E, 1,245N, 1,247I, 1,257I, 1,258D, 1,261S, 1,275G, 1,276T, 1,277L, 1,278D
CDD
cd14004 (STKc_PASK)
polypeptide substr...

1,116A

polypeptide substrate binding site
1,116A, 1,201D, 1,203F, 1,240D, 1,242K, 1,244E, 1,261S, 1,275G, 1,276T, 1,277L, 1,278D
CDD
cd14004 (STKc_PASK)

1,201D

polypeptide substrate binding site
1,116A, 1,201D, 1,203F, 1,240D, 1,242K, 1,244E, 1,261S, 1,275G, 1,276T, 1,277L, 1,278D
CDD
cd14004 (STKc_PASK)

1,203F

polypeptide substrate binding site
1,116A, 1,201D, 1,203F, 1,240D, 1,242K, 1,244E, 1,261S, 1,275G, 1,276T, 1,277L, 1,278D
CDD
cd14004 (STKc_PASK)

1,240D

polypeptide substrate binding site
1,116A, 1,201D, 1,203F, 1,240D, 1,242K, 1,244E, 1,261S, 1,275G, 1,276T, 1,277L, 1,278D
CDD
cd14004 (STKc_PASK)

1,242K

polypeptide substrate binding site
1,116A, 1,201D, 1,203F, 1,240D, 1,242K, 1,244E, 1,261S, 1,275G, 1,276T, 1,277L, 1,278D
CDD
cd14004 (STKc_PASK)

1,244E

polypeptide substrate binding site
1,116A, 1,201D, 1,203F, 1,240D, 1,242K, 1,244E, 1,261S, 1,275G, 1,276T, 1,277L, 1,278D
CDD
cd14004 (STKc_PASK)

1,261S

polypeptide substrate binding site
1,116A, 1,201D, 1,203F, 1,240D, 1,242K, 1,244E, 1,261S, 1,275G, 1,276T, 1,277L, 1,278D
CDD
cd14004 (STKc_PASK)

1,275G

polypeptide substrate binding site
1,116A, 1,201D, 1,203F, 1,240D, 1,242K, 1,244E, 1,261S, 1,275G, 1,276T, 1,277L, 1,278D
CDD
cd14004 (STKc_PASK)

1,276T

polypeptide substrate binding site
1,116A, 1,201D, 1,203F, 1,240D, 1,242K, 1,244E, 1,261S, 1,275G, 1,276T, 1,277L, 1,278D
CDD
cd14004 (STKc_PASK)

1,277L

polypeptide substrate binding site
1,116A, 1,201D, 1,203F, 1,240D, 1,242K, 1,244E, 1,261S, 1,275G, 1,276T, 1,277L, 1,278D
CDD
cd14004 (STKc_PASK)

1,278D

polypeptide substrate binding site
1,116A, 1,201D, 1,203F, 1,240D, 1,242K, 1,244E, 1,261S, 1,275G, 1,276T, 1,277L, 1,278D
CDD
cd14004 (STKc_PASK)
activation loop (A...

1,257I

activation loop (A-loop)
1,257I, 1,258D, 1,259F, 1,260G, 1,261S, 1,262S, 1,263A, 1,264F, 1,265V, 1,266R, 1,267Q, 1,268G, 1,269P, 1,270F, 1,271D, 1,272V, 1,273F, 1,274V, 1,275G, 1,276T, 1,277L, 1,278D
CDD
cd14004 (STKc_PASK)

1,258D

activation loop (A-loop)
1,257I, 1,258D, 1,259F, 1,260G, 1,261S, 1,262S, 1,263A, 1,264F, 1,265V, 1,266R, 1,267Q, 1,268G, 1,269P, 1,270F, 1,271D, 1,272V, 1,273F, 1,274V, 1,275G, 1,276T, 1,277L, 1,278D
CDD
cd14004 (STKc_PASK)

1,259F

activation loop (A-loop)
1,257I, 1,258D, 1,259F, 1,260G, 1,261S, 1,262S, 1,263A, 1,264F, 1,265V, 1,266R, 1,267Q, 1,268G, 1,269P, 1,270F, 1,271D, 1,272V, 1,273F, 1,274V, 1,275G, 1,276T, 1,277L, 1,278D
CDD
cd14004 (STKc_PASK)

1,260G

activation loop (A-loop)
1,257I, 1,258D, 1,259F, 1,260G, 1,261S, 1,262S, 1,263A, 1,264F, 1,265V, 1,266R, 1,267Q, 1,268G, 1,269P, 1,270F, 1,271D, 1,272V, 1,273F, 1,274V, 1,275G, 1,276T, 1,277L, 1,278D
CDD
cd14004 (STKc_PASK)

1,261S

activation loop (A-loop)
1,257I, 1,258D, 1,259F, 1,260G, 1,261S, 1,262S, 1,263A, 1,264F, 1,265V, 1,266R, 1,267Q, 1,268G, 1,269P, 1,270F, 1,271D, 1,272V, 1,273F, 1,274V, 1,275G, 1,276T, 1,277L, 1,278D
CDD
cd14004 (STKc_PASK)

1,262S

activation loop (A-loop)
1,257I, 1,258D, 1,259F, 1,260G, 1,261S, 1,262S, 1,263A, 1,264F, 1,265V, 1,266R, 1,267Q, 1,268G, 1,269P, 1,270F, 1,271D, 1,272V, 1,273F, 1,274V, 1,275G, 1,276T, 1,277L, 1,278D
CDD
cd14004 (STKc_PASK)

1,263A

activation loop (A-loop)
1,257I, 1,258D, 1,259F, 1,260G, 1,261S, 1,262S, 1,263A, 1,264F, 1,265V, 1,266R, 1,267Q, 1,268G, 1,269P, 1,270F, 1,271D, 1,272V, 1,273F, 1,274V, 1,275G, 1,276T, 1,277L, 1,278D
CDD
cd14004 (STKc_PASK)

1,264F

activation loop (A-loop)
1,257I, 1,258D, 1,259F, 1,260G, 1,261S, 1,262S, 1,263A, 1,264F, 1,265V, 1,266R, 1,267Q, 1,268G, 1,269P, 1,270F, 1,271D, 1,272V, 1,273F, 1,274V, 1,275G, 1,276T, 1,277L, 1,278D
CDD
cd14004 (STKc_PASK)

1,265V

activation loop (A-loop)
1,257I, 1,258D, 1,259F, 1,260G, 1,261S, 1,262S, 1,263A, 1,264F, 1,265V, 1,266R, 1,267Q, 1,268G, 1,269P, 1,270F, 1,271D, 1,272V, 1,273F, 1,274V, 1,275G, 1,276T, 1,277L, 1,278D
CDD
cd14004 (STKc_PASK)

1,266R

activation loop (A-loop)
1,257I, 1,258D, 1,259F, 1,260G, 1,261S, 1,262S, 1,263A, 1,264F, 1,265V, 1,266R, 1,267Q, 1,268G, 1,269P, 1,270F, 1,271D, 1,272V, 1,273F, 1,274V, 1,275G, 1,276T, 1,277L, 1,278D
CDD
cd14004 (STKc_PASK)

1,267Q

activation loop (A-loop)
1,257I, 1,258D, 1,259F, 1,260G, 1,261S, 1,262S, 1,263A, 1,264F, 1,265V, 1,266R, 1,267Q, 1,268G, 1,269P, 1,270F, 1,271D, 1,272V, 1,273F, 1,274V, 1,275G, 1,276T, 1,277L, 1,278D
CDD
cd14004 (STKc_PASK)

1,268G

activation loop (A-loop)
1,257I, 1,258D, 1,259F, 1,260G, 1,261S, 1,262S, 1,263A, 1,264F, 1,265V, 1,266R, 1,267Q, 1,268G, 1,269P, 1,270F, 1,271D, 1,272V, 1,273F, 1,274V, 1,275G, 1,276T, 1,277L, 1,278D
CDD
cd14004 (STKc_PASK)

1,269P

activation loop (A-loop)
1,257I, 1,258D, 1,259F, 1,260G, 1,261S, 1,262S, 1,263A, 1,264F, 1,265V, 1,266R, 1,267Q, 1,268G, 1,269P, 1,270F, 1,271D, 1,272V, 1,273F, 1,274V, 1,275G, 1,276T, 1,277L, 1,278D
CDD
cd14004 (STKc_PASK)

1,270F

activation loop (A-loop)
1,257I, 1,258D, 1,259F, 1,260G, 1,261S, 1,262S, 1,263A, 1,264F, 1,265V, 1,266R, 1,267Q, 1,268G, 1,269P, 1,270F, 1,271D, 1,272V, 1,273F, 1,274V, 1,275G, 1,276T, 1,277L, 1,278D
CDD
cd14004 (STKc_PASK)

1,271D

activation loop (A-loop)
1,257I, 1,258D, 1,259F, 1,260G, 1,261S, 1,262S, 1,263A, 1,264F, 1,265V, 1,266R, 1,267Q, 1,268G, 1,269P, 1,270F, 1,271D, 1,272V, 1,273F, 1,274V, 1,275G, 1,276T, 1,277L, 1,278D
CDD
cd14004 (STKc_PASK)

1,272V

activation loop (A-loop)
1,257I, 1,258D, 1,259F, 1,260G, 1,261S, 1,262S, 1,263A, 1,264F, 1,265V, 1,266R, 1,267Q, 1,268G, 1,269P, 1,270F, 1,271D, 1,272V, 1,273F, 1,274V, 1,275G, 1,276T, 1,277L, 1,278D
CDD
cd14004 (STKc_PASK)

1,273F

activation loop (A-loop)
1,257I, 1,258D, 1,259F, 1,260G, 1,261S, 1,262S, 1,263A, 1,264F, 1,265V, 1,266R, 1,267Q, 1,268G, 1,269P, 1,270F, 1,271D, 1,272V, 1,273F, 1,274V, 1,275G, 1,276T, 1,277L, 1,278D
CDD
cd14004 (STKc_PASK)

1,274V

activation loop (A-loop)
1,257I, 1,258D, 1,259F, 1,260G, 1,261S, 1,262S, 1,263A, 1,264F, 1,265V, 1,266R, 1,267Q, 1,268G, 1,269P, 1,270F, 1,271D, 1,272V, 1,273F, 1,274V, 1,275G, 1,276T, 1,277L, 1,278D
CDD
cd14004 (STKc_PASK)

1,275G

activation loop (A-loop)
1,257I, 1,258D, 1,259F, 1,260G, 1,261S, 1,262S, 1,263A, 1,264F, 1,265V, 1,266R, 1,267Q, 1,268G, 1,269P, 1,270F, 1,271D, 1,272V, 1,273F, 1,274V, 1,275G, 1,276T, 1,277L, 1,278D
CDD
cd14004 (STKc_PASK)

1,276T

activation loop (A-loop)
1,257I, 1,258D, 1,259F, 1,260G, 1,261S, 1,262S, 1,263A, 1,264F, 1,265V, 1,266R, 1,267Q, 1,268G, 1,269P, 1,270F, 1,271D, 1,272V, 1,273F, 1,274V, 1,275G, 1,276T, 1,277L, 1,278D
CDD
cd14004 (STKc_PASK)

1,277L

activation loop (A-loop)
1,257I, 1,258D, 1,259F, 1,260G, 1,261S, 1,262S, 1,263A, 1,264F, 1,265V, 1,266R, 1,267Q, 1,268G, 1,269P, 1,270F, 1,271D, 1,272V, 1,273F, 1,274V, 1,275G, 1,276T, 1,277L, 1,278D
CDD
cd14004 (STKc_PASK)

1,278D

activation loop (A-loop)
1,257I, 1,258D, 1,259F, 1,260G, 1,261S, 1,262S, 1,263A, 1,264F, 1,265V, 1,266R, 1,267Q, 1,268G, 1,269P, 1,270F, 1,271D, 1,272V, 1,273F, 1,274V, 1,275G, 1,276T, 1,277L, 1,278D
CDD
cd14004 (STKc_PASK)

Protein sequence

>MIA_04020_1
MTPSATESLNPPSSSHLMSERRRPSFHIDTSSDEEDEIDVGSPGSDSIALNTSSPSSSSPSSSSTINPASIIHPSGSAAA
HKPPQLAYSLSSAAPVSSRLSPELKRVSTSPTTTYIQQQRVPSAHNPQPPHMHQHPHLAGFGSHTQLSTLLQQHQATPMS
SELVQRFTSQSLHSFSFAFVSQNAISSRLDILKRSLEFLRDNPALTSMSNFPSTSSTTALEDFFKSPTPSRTQLRSSASS
AALSMLANYPVMGGAAGMTQGPPSFLGASSQQHSSVGAFSAAAAGAFSAAAAAAAGAPPMARGATTANATSAAHALLGEP
SNTLFDNNLKSILTLLENAHVFPASGSSLPYAPPVATTATSSSDNNPLSSPTSNSKLYSVLAAPKPQQQDAQPPTPFKPI
NGNEHIIAAPPALSTTPKPTNTPIPHSPIPQGKKKSSLLEPPKFRKRTKTNIATFHLQAQLLDALATPYYDPYWTNLIQR
TGTISSMPTISTSASTVDLKSAGFRNPSMFSSASSILHPISSRFSSNQAVFTTSSDDPYRILASNDISCLVFGMSKLEIR
RQTISDIVGPNFREGVIERARHCPPNTTFFCGELIPIVKCTGQSGLASFFAKKHNSGIIAWVIEEIAHDRANLTVNLTNG
SLTVSGPQKHVLFPEDDDDATLNIRETFSGIPDNLNVMANNLRNNKRHVENHVTVSGNTAVPTMFQIADDDKPDQDNGNI
LSLQLVSIPHMAGIILLDPAQMTIAGYNASVVEQLFGYPETDAKHCVGWSIDKLIPNFTAYVEHIERTCDLNLRGRMHQG
LVVPEHLFRKAAVEIQMEQQLQQQPSSQPGSEFDSPLGSESATARASPVSTEESSDQESDDELSDLPMHLSNGHIAPATS
SSSKLHQRFALSDGGGFMPKKQLGIISAFMDSKGIEALHRDGISLVVDVQMRIIGDGNAALWVTYSRNIIGQQESNEIPS
QLTLFSMKNKLGIKRFSSLSEPAAAAAGTATASTTSTAATSTASNEFLPKLANGQPLTPSQSHQDEKPVTPESKPVSQSS
NDSTITTTTTMETATTATTTTTTTGTPRAQIISQASSETPNSASSAYSIHIPELGARRREKTLADFKILKRMGEGAYGKV
ILAEYAVEPPLRVVLKSVIKERILVDTWTRDRKLGTIPSEIKVMAVLTKWPHENIVQLLDFFEDEEYFHIEMEPHGNPGT
DLFDLIENQPDMPESQCRSLFKQVVSAVRHLHVHDIVHRDIKDENVIVDGTGLVKLIDFGSSAFVRQGPFDVFVGTLDYA
APEVLAGKPYEGKPQDVWALGILLYTIIYKENPFYNVDEIMDHDLRVPFVISEPCIDLIRMILTRPVRKRPSVEDIWNHP
WIQAE

GO term prediction

Biological Process

GO:0006468 protein phosphorylation

Molecular Function

GO:0004672 protein kinase activity
GO:0005524 ATP binding

Cellular Component