MCA_02218_1

Protein

Length

1,458 amino acids

Gene name: PSK2

Description: PAS-domain containing serine/threonine protein kinase

Browser: contigB:627785-632245-

RNA-seq: read pairs 2460, FPKM 20.8, percentile rank 42.5% (100% = highest expression)

Protein function

Annotation:		PSK2	PAS-domain containing serine/threonine protein kinase
KEGG:	K08286	E2.7.11.-	protein-serine/threonine kinase [EC:2.7.11.-]
EGGNOG:	0PHZ4	FG06970.1	negative regulation of glycogen biosynthetic process
SGD closest match:	S000005405	PSK2	Serine/threonine-protein kinase PSK2
CGD closest match:	CAL0000200971	FUN31	Serine/threonine protein kinase

Protein alignments

	%id	Aln length	E-value
MIA_04020_1	51.36%	701	0.0	MIA_04020_1
A0A0J9XJ98_GEOCN	75.17%	298	1e-161	Similar to Saccharomyces cerevisiae YOL045W PSK2 One of two (See also PSK1) PAS domain containing S/T protein kinases OS=Geotrichum candidum GN=BN980_GECA20s01363g PE=4 SV=1
UniRef50_A0A0J9XJ98	75.17%	298	2e-158	Similar to Saccharomyces cerevisiae YOL045W PSK2 One of two (See also PSK1) PAS domain containing S/T protein kinases n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XJ98_GEOCN
A0A060TH49_BLAAD	71.48%	277	3e-134	ARAD1D35970p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D35970g PE=4 SV=1
A0A167ECK2_9ASCO	65.74%	289	7e-127	Serine/threonine protein kinase PSK2 OS=Sugiyamaella lignohabitans GN=PSK2 PE=4 SV=1
Q6C310_YARLI	62.12%	293	1e-125	YALI0F03542p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F03542g PE=4 SV=1
A0A1D8PKQ6_CANAL	65.83%	278	6e-118	Serine/threonine protein kinase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=FUN31 PE=4 SV=1
A0A1E3PFS3_9ASCO	64.47%	273	2e-127	Pkinase-domain-containing protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_83733 PE=4 SV=1
PSK2_YEAST	65.20%	273	4e-111	Serine/threonine-protein kinase PSK2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PSK2 PE=1 SV=1
A0A1E4TA86_9ASCO	59.63%	270	6e-116	Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_29437 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0488

Protein family membership

None predicted.

Domains and repeats

Domain
1,189 - 1,453
Protein kinase-like domain (IPR011009)
Protein kinase domain (IPR000719)

1 200 400 600 800 1000 1200 1458

Detailed signature matches

IPR011009

Protein kinase-like domain
1. SSF56112 (Protein k...)
  
  1,189 - 1,453
  
  SUPERFAMILY
  SSF56112 (Protein kinase-like (PK-like))
IPR000719

Protein kinase domain
1. PS50011 (PROTEIN_KI...)
  
  1,195 - 1,451
  
  PROSITE profiles
  PS50011 (PROTEIN_KINASE_DOM)
2. SM00220 (serkin_6)
  
  1,195 - 1,451
  
  SMART
  SM00220 (serkin_6)
3. PF00069 (Pkinase)
  
  1,195 - 1,451
  
  Pfam
  PF00069 (Pkinase)
IPR008271

Serine/threonine-protein kinase, active site
1. PS00108 (PROTEIN_KI...)
  
  1,325 - 1,337
  
  PROSITE patterns
  PS00108 (PROTEIN_KINASE_ST)

no IPR

Unintegrated signatures

Coil

828 - 848

COILS
Coil (Coil)
G3DSA:1.10.51...

1,305 - 1,458

GENE3D
G3DSA:1.10.510.10 (G3DSA:1.10.510.10)
G3DSA:3.30.20...

871 - 1,304

GENE3D
G3DSA:3.30.200.20 (G3DSA:3.30.200.20)
cd14004 (STKc_PASK)

1,194 - 1,451

CDD
cd14004 (STKc_PASK)
mobidb-lite (disord...)

126 - 157

MobiDB Lite
mobidb-lite (disorder_prediction)

1 - 95

MobiDB Lite
mobidb-lite (disorder_prediction)

832 - 895

MobiDB Lite
mobidb-lite (disorder_prediction)

363 - 400

MobiDB Lite
mobidb-lite (disorder_prediction)

700 - 724

MobiDB Lite
mobidb-lite (disorder_prediction)

999 - 1,170

MobiDB Lite
mobidb-lite (disorder_prediction)

Residue annotation

ATP binding site c...

1,201M

ATP binding site
1,201M, 1,202G, 1,209V, 1,223V, 1,225K, 1,265I, 1,281L, 1,282E, 1,283P, 1,284H, 1,288G, 1,290D, 1,333E, 1,334N, 1,336I, 1,346I, 1,347D
CDD
cd14004 (STKc_PASK)

1,202G

ATP binding site
1,201M, 1,202G, 1,209V, 1,223V, 1,225K, 1,265I, 1,281L, 1,282E, 1,283P, 1,284H, 1,288G, 1,290D, 1,333E, 1,334N, 1,336I, 1,346I, 1,347D
CDD
cd14004 (STKc_PASK)

1,209V

ATP binding site
1,201M, 1,202G, 1,209V, 1,223V, 1,225K, 1,265I, 1,281L, 1,282E, 1,283P, 1,284H, 1,288G, 1,290D, 1,333E, 1,334N, 1,336I, 1,346I, 1,347D
CDD
cd14004 (STKc_PASK)

1,223V

ATP binding site
1,201M, 1,202G, 1,209V, 1,223V, 1,225K, 1,265I, 1,281L, 1,282E, 1,283P, 1,284H, 1,288G, 1,290D, 1,333E, 1,334N, 1,336I, 1,346I, 1,347D
CDD
cd14004 (STKc_PASK)

1,225K

ATP binding site
1,201M, 1,202G, 1,209V, 1,223V, 1,225K, 1,265I, 1,281L, 1,282E, 1,283P, 1,284H, 1,288G, 1,290D, 1,333E, 1,334N, 1,336I, 1,346I, 1,347D
CDD
cd14004 (STKc_PASK)

1,265I

ATP binding site
1,201M, 1,202G, 1,209V, 1,223V, 1,225K, 1,265I, 1,281L, 1,282E, 1,283P, 1,284H, 1,288G, 1,290D, 1,333E, 1,334N, 1,336I, 1,346I, 1,347D
CDD
cd14004 (STKc_PASK)

1,281L

ATP binding site
1,201M, 1,202G, 1,209V, 1,223V, 1,225K, 1,265I, 1,281L, 1,282E, 1,283P, 1,284H, 1,288G, 1,290D, 1,333E, 1,334N, 1,336I, 1,346I, 1,347D
CDD
cd14004 (STKc_PASK)

1,282E

ATP binding site
1,201M, 1,202G, 1,209V, 1,223V, 1,225K, 1,265I, 1,281L, 1,282E, 1,283P, 1,284H, 1,288G, 1,290D, 1,333E, 1,334N, 1,336I, 1,346I, 1,347D
CDD
cd14004 (STKc_PASK)

1,283P

ATP binding site
1,201M, 1,202G, 1,209V, 1,223V, 1,225K, 1,265I, 1,281L, 1,282E, 1,283P, 1,284H, 1,288G, 1,290D, 1,333E, 1,334N, 1,336I, 1,346I, 1,347D
CDD
cd14004 (STKc_PASK)

1,284H

ATP binding site
1,201M, 1,202G, 1,209V, 1,223V, 1,225K, 1,265I, 1,281L, 1,282E, 1,283P, 1,284H, 1,288G, 1,290D, 1,333E, 1,334N, 1,336I, 1,346I, 1,347D
CDD
cd14004 (STKc_PASK)

1,288G

ATP binding site
1,201M, 1,202G, 1,209V, 1,223V, 1,225K, 1,265I, 1,281L, 1,282E, 1,283P, 1,284H, 1,288G, 1,290D, 1,333E, 1,334N, 1,336I, 1,346I, 1,347D
CDD
cd14004 (STKc_PASK)

1,290D

ATP binding site
1,201M, 1,202G, 1,209V, 1,223V, 1,225K, 1,265I, 1,281L, 1,282E, 1,283P, 1,284H, 1,288G, 1,290D, 1,333E, 1,334N, 1,336I, 1,346I, 1,347D
CDD
cd14004 (STKc_PASK)

1,333E

ATP binding site
1,201M, 1,202G, 1,209V, 1,223V, 1,225K, 1,265I, 1,281L, 1,282E, 1,283P, 1,284H, 1,288G, 1,290D, 1,333E, 1,334N, 1,336I, 1,346I, 1,347D
CDD
cd14004 (STKc_PASK)

1,334N

ATP binding site
1,201M, 1,202G, 1,209V, 1,223V, 1,225K, 1,265I, 1,281L, 1,282E, 1,283P, 1,284H, 1,288G, 1,290D, 1,333E, 1,334N, 1,336I, 1,346I, 1,347D
CDD
cd14004 (STKc_PASK)

1,336I

ATP binding site
1,201M, 1,202G, 1,209V, 1,223V, 1,225K, 1,265I, 1,281L, 1,282E, 1,283P, 1,284H, 1,288G, 1,290D, 1,333E, 1,334N, 1,336I, 1,346I, 1,347D
CDD
cd14004 (STKc_PASK)

1,346I

ATP binding site
1,201M, 1,202G, 1,209V, 1,223V, 1,225K, 1,265I, 1,281L, 1,282E, 1,283P, 1,284H, 1,288G, 1,290D, 1,333E, 1,334N, 1,336I, 1,346I, 1,347D
CDD
cd14004 (STKc_PASK)

1,347D

ATP binding site
1,201M, 1,202G, 1,209V, 1,223V, 1,225K, 1,265I, 1,281L, 1,282E, 1,283P, 1,284H, 1,288G, 1,290D, 1,333E, 1,334N, 1,336I, 1,346I, 1,347D
CDD
cd14004 (STKc_PASK)
active site cd14004

1,201M

active site
1,201M, 1,202G, 1,203E, 1,204G, 1,205A, 1,209V, 1,223V, 1,225K, 1,265I, 1,281L, 1,282E, 1,283P, 1,284H, 1,290D, 1,292F, 1,329D, 1,331K, 1,333E, 1,334N, 1,336I, 1,346I, 1,347D, 1,350S, 1,364G, 1,365T, 1,366I, 1,367D
CDD
cd14004 (STKc_PASK)

1,202G

active site
1,201M, 1,202G, 1,203E, 1,204G, 1,205A, 1,209V, 1,223V, 1,225K, 1,265I, 1,281L, 1,282E, 1,283P, 1,284H, 1,290D, 1,292F, 1,329D, 1,331K, 1,333E, 1,334N, 1,336I, 1,346I, 1,347D, 1,350S, 1,364G, 1,365T, 1,366I, 1,367D
CDD
cd14004 (STKc_PASK)

1,203E

active site
1,201M, 1,202G, 1,203E, 1,204G, 1,205A, 1,209V, 1,223V, 1,225K, 1,265I, 1,281L, 1,282E, 1,283P, 1,284H, 1,290D, 1,292F, 1,329D, 1,331K, 1,333E, 1,334N, 1,336I, 1,346I, 1,347D, 1,350S, 1,364G, 1,365T, 1,366I, 1,367D
CDD
cd14004 (STKc_PASK)

1,204G

active site
1,201M, 1,202G, 1,203E, 1,204G, 1,205A, 1,209V, 1,223V, 1,225K, 1,265I, 1,281L, 1,282E, 1,283P, 1,284H, 1,290D, 1,292F, 1,329D, 1,331K, 1,333E, 1,334N, 1,336I, 1,346I, 1,347D, 1,350S, 1,364G, 1,365T, 1,366I, 1,367D
CDD
cd14004 (STKc_PASK)

1,205A

active site
1,201M, 1,202G, 1,203E, 1,204G, 1,205A, 1,209V, 1,223V, 1,225K, 1,265I, 1,281L, 1,282E, 1,283P, 1,284H, 1,290D, 1,292F, 1,329D, 1,331K, 1,333E, 1,334N, 1,336I, 1,346I, 1,347D, 1,350S, 1,364G, 1,365T, 1,366I, 1,367D
CDD
cd14004 (STKc_PASK)

1,209V

active site
1,201M, 1,202G, 1,203E, 1,204G, 1,205A, 1,209V, 1,223V, 1,225K, 1,265I, 1,281L, 1,282E, 1,283P, 1,284H, 1,290D, 1,292F, 1,329D, 1,331K, 1,333E, 1,334N, 1,336I, 1,346I, 1,347D, 1,350S, 1,364G, 1,365T, 1,366I, 1,367D
CDD
cd14004 (STKc_PASK)

1,223V

active site
1,201M, 1,202G, 1,203E, 1,204G, 1,205A, 1,209V, 1,223V, 1,225K, 1,265I, 1,281L, 1,282E, 1,283P, 1,284H, 1,290D, 1,292F, 1,329D, 1,331K, 1,333E, 1,334N, 1,336I, 1,346I, 1,347D, 1,350S, 1,364G, 1,365T, 1,366I, 1,367D
CDD
cd14004 (STKc_PASK)

1,225K

active site
1,201M, 1,202G, 1,203E, 1,204G, 1,205A, 1,209V, 1,223V, 1,225K, 1,265I, 1,281L, 1,282E, 1,283P, 1,284H, 1,290D, 1,292F, 1,329D, 1,331K, 1,333E, 1,334N, 1,336I, 1,346I, 1,347D, 1,350S, 1,364G, 1,365T, 1,366I, 1,367D
CDD
cd14004 (STKc_PASK)

1,265I

active site
1,201M, 1,202G, 1,203E, 1,204G, 1,205A, 1,209V, 1,223V, 1,225K, 1,265I, 1,281L, 1,282E, 1,283P, 1,284H, 1,290D, 1,292F, 1,329D, 1,331K, 1,333E, 1,334N, 1,336I, 1,346I, 1,347D, 1,350S, 1,364G, 1,365T, 1,366I, 1,367D
CDD
cd14004 (STKc_PASK)

1,281L

active site
1,201M, 1,202G, 1,203E, 1,204G, 1,205A, 1,209V, 1,223V, 1,225K, 1,265I, 1,281L, 1,282E, 1,283P, 1,284H, 1,290D, 1,292F, 1,329D, 1,331K, 1,333E, 1,334N, 1,336I, 1,346I, 1,347D, 1,350S, 1,364G, 1,365T, 1,366I, 1,367D
CDD
cd14004 (STKc_PASK)

1,282E

active site
1,201M, 1,202G, 1,203E, 1,204G, 1,205A, 1,209V, 1,223V, 1,225K, 1,265I, 1,281L, 1,282E, 1,283P, 1,284H, 1,290D, 1,292F, 1,329D, 1,331K, 1,333E, 1,334N, 1,336I, 1,346I, 1,347D, 1,350S, 1,364G, 1,365T, 1,366I, 1,367D
CDD
cd14004 (STKc_PASK)

1,283P

active site
1,201M, 1,202G, 1,203E, 1,204G, 1,205A, 1,209V, 1,223V, 1,225K, 1,265I, 1,281L, 1,282E, 1,283P, 1,284H, 1,290D, 1,292F, 1,329D, 1,331K, 1,333E, 1,334N, 1,336I, 1,346I, 1,347D, 1,350S, 1,364G, 1,365T, 1,366I, 1,367D
CDD
cd14004 (STKc_PASK)

1,284H

active site
1,201M, 1,202G, 1,203E, 1,204G, 1,205A, 1,209V, 1,223V, 1,225K, 1,265I, 1,281L, 1,282E, 1,283P, 1,284H, 1,290D, 1,292F, 1,329D, 1,331K, 1,333E, 1,334N, 1,336I, 1,346I, 1,347D, 1,350S, 1,364G, 1,365T, 1,366I, 1,367D
CDD
cd14004 (STKc_PASK)

1,290D

active site
1,201M, 1,202G, 1,203E, 1,204G, 1,205A, 1,209V, 1,223V, 1,225K, 1,265I, 1,281L, 1,282E, 1,283P, 1,284H, 1,290D, 1,292F, 1,329D, 1,331K, 1,333E, 1,334N, 1,336I, 1,346I, 1,347D, 1,350S, 1,364G, 1,365T, 1,366I, 1,367D
CDD
cd14004 (STKc_PASK)

1,292F

active site
1,201M, 1,202G, 1,203E, 1,204G, 1,205A, 1,209V, 1,223V, 1,225K, 1,265I, 1,281L, 1,282E, 1,283P, 1,284H, 1,290D, 1,292F, 1,329D, 1,331K, 1,333E, 1,334N, 1,336I, 1,346I, 1,347D, 1,350S, 1,364G, 1,365T, 1,366I, 1,367D
CDD
cd14004 (STKc_PASK)

1,329D

active site
1,201M, 1,202G, 1,203E, 1,204G, 1,205A, 1,209V, 1,223V, 1,225K, 1,265I, 1,281L, 1,282E, 1,283P, 1,284H, 1,290D, 1,292F, 1,329D, 1,331K, 1,333E, 1,334N, 1,336I, 1,346I, 1,347D, 1,350S, 1,364G, 1,365T, 1,366I, 1,367D
CDD
cd14004 (STKc_PASK)

1,331K

active site
1,201M, 1,202G, 1,203E, 1,204G, 1,205A, 1,209V, 1,223V, 1,225K, 1,265I, 1,281L, 1,282E, 1,283P, 1,284H, 1,290D, 1,292F, 1,329D, 1,331K, 1,333E, 1,334N, 1,336I, 1,346I, 1,347D, 1,350S, 1,364G, 1,365T, 1,366I, 1,367D
CDD
cd14004 (STKc_PASK)

1,333E

active site
1,201M, 1,202G, 1,203E, 1,204G, 1,205A, 1,209V, 1,223V, 1,225K, 1,265I, 1,281L, 1,282E, 1,283P, 1,284H, 1,290D, 1,292F, 1,329D, 1,331K, 1,333E, 1,334N, 1,336I, 1,346I, 1,347D, 1,350S, 1,364G, 1,365T, 1,366I, 1,367D
CDD
cd14004 (STKc_PASK)

1,334N

active site
1,201M, 1,202G, 1,203E, 1,204G, 1,205A, 1,209V, 1,223V, 1,225K, 1,265I, 1,281L, 1,282E, 1,283P, 1,284H, 1,290D, 1,292F, 1,329D, 1,331K, 1,333E, 1,334N, 1,336I, 1,346I, 1,347D, 1,350S, 1,364G, 1,365T, 1,366I, 1,367D
CDD
cd14004 (STKc_PASK)

1,336I

active site
1,201M, 1,202G, 1,203E, 1,204G, 1,205A, 1,209V, 1,223V, 1,225K, 1,265I, 1,281L, 1,282E, 1,283P, 1,284H, 1,290D, 1,292F, 1,329D, 1,331K, 1,333E, 1,334N, 1,336I, 1,346I, 1,347D, 1,350S, 1,364G, 1,365T, 1,366I, 1,367D
CDD
cd14004 (STKc_PASK)

1,346I

active site
1,201M, 1,202G, 1,203E, 1,204G, 1,205A, 1,209V, 1,223V, 1,225K, 1,265I, 1,281L, 1,282E, 1,283P, 1,284H, 1,290D, 1,292F, 1,329D, 1,331K, 1,333E, 1,334N, 1,336I, 1,346I, 1,347D, 1,350S, 1,364G, 1,365T, 1,366I, 1,367D
CDD
cd14004 (STKc_PASK)

1,347D

active site
1,201M, 1,202G, 1,203E, 1,204G, 1,205A, 1,209V, 1,223V, 1,225K, 1,265I, 1,281L, 1,282E, 1,283P, 1,284H, 1,290D, 1,292F, 1,329D, 1,331K, 1,333E, 1,334N, 1,336I, 1,346I, 1,347D, 1,350S, 1,364G, 1,365T, 1,366I, 1,367D
CDD
cd14004 (STKc_PASK)

1,350S

active site
1,201M, 1,202G, 1,203E, 1,204G, 1,205A, 1,209V, 1,223V, 1,225K, 1,265I, 1,281L, 1,282E, 1,283P, 1,284H, 1,290D, 1,292F, 1,329D, 1,331K, 1,333E, 1,334N, 1,336I, 1,346I, 1,347D, 1,350S, 1,364G, 1,365T, 1,366I, 1,367D
CDD
cd14004 (STKc_PASK)

1,364G

active site
1,201M, 1,202G, 1,203E, 1,204G, 1,205A, 1,209V, 1,223V, 1,225K, 1,265I, 1,281L, 1,282E, 1,283P, 1,284H, 1,290D, 1,292F, 1,329D, 1,331K, 1,333E, 1,334N, 1,336I, 1,346I, 1,347D, 1,350S, 1,364G, 1,365T, 1,366I, 1,367D
CDD
cd14004 (STKc_PASK)

1,365T

active site
1,201M, 1,202G, 1,203E, 1,204G, 1,205A, 1,209V, 1,223V, 1,225K, 1,265I, 1,281L, 1,282E, 1,283P, 1,284H, 1,290D, 1,292F, 1,329D, 1,331K, 1,333E, 1,334N, 1,336I, 1,346I, 1,347D, 1,350S, 1,364G, 1,365T, 1,366I, 1,367D
CDD
cd14004 (STKc_PASK)

1,366I

active site
1,201M, 1,202G, 1,203E, 1,204G, 1,205A, 1,209V, 1,223V, 1,225K, 1,265I, 1,281L, 1,282E, 1,283P, 1,284H, 1,290D, 1,292F, 1,329D, 1,331K, 1,333E, 1,334N, 1,336I, 1,346I, 1,347D, 1,350S, 1,364G, 1,365T, 1,366I, 1,367D
CDD
cd14004 (STKc_PASK)

1,367D

active site
1,201M, 1,202G, 1,203E, 1,204G, 1,205A, 1,209V, 1,223V, 1,225K, 1,265I, 1,281L, 1,282E, 1,283P, 1,284H, 1,290D, 1,292F, 1,329D, 1,331K, 1,333E, 1,334N, 1,336I, 1,346I, 1,347D, 1,350S, 1,364G, 1,365T, 1,366I, 1,367D
CDD
cd14004 (STKc_PASK)
polypeptide substr...

1,205A

polypeptide substrate binding site
1,205A, 1,290D, 1,292F, 1,329D, 1,331K, 1,333E, 1,350S, 1,364G, 1,365T, 1,366I, 1,367D
CDD
cd14004 (STKc_PASK)

1,290D

polypeptide substrate binding site
1,205A, 1,290D, 1,292F, 1,329D, 1,331K, 1,333E, 1,350S, 1,364G, 1,365T, 1,366I, 1,367D
CDD
cd14004 (STKc_PASK)

1,292F

polypeptide substrate binding site
1,205A, 1,290D, 1,292F, 1,329D, 1,331K, 1,333E, 1,350S, 1,364G, 1,365T, 1,366I, 1,367D
CDD
cd14004 (STKc_PASK)

1,329D

polypeptide substrate binding site
1,205A, 1,290D, 1,292F, 1,329D, 1,331K, 1,333E, 1,350S, 1,364G, 1,365T, 1,366I, 1,367D
CDD
cd14004 (STKc_PASK)

1,331K

polypeptide substrate binding site
1,205A, 1,290D, 1,292F, 1,329D, 1,331K, 1,333E, 1,350S, 1,364G, 1,365T, 1,366I, 1,367D
CDD
cd14004 (STKc_PASK)

1,333E

polypeptide substrate binding site
1,205A, 1,290D, 1,292F, 1,329D, 1,331K, 1,333E, 1,350S, 1,364G, 1,365T, 1,366I, 1,367D
CDD
cd14004 (STKc_PASK)

1,350S

polypeptide substrate binding site
1,205A, 1,290D, 1,292F, 1,329D, 1,331K, 1,333E, 1,350S, 1,364G, 1,365T, 1,366I, 1,367D
CDD
cd14004 (STKc_PASK)

1,364G

polypeptide substrate binding site
1,205A, 1,290D, 1,292F, 1,329D, 1,331K, 1,333E, 1,350S, 1,364G, 1,365T, 1,366I, 1,367D
CDD
cd14004 (STKc_PASK)

1,365T

polypeptide substrate binding site
1,205A, 1,290D, 1,292F, 1,329D, 1,331K, 1,333E, 1,350S, 1,364G, 1,365T, 1,366I, 1,367D
CDD
cd14004 (STKc_PASK)

1,366I

polypeptide substrate binding site
1,205A, 1,290D, 1,292F, 1,329D, 1,331K, 1,333E, 1,350S, 1,364G, 1,365T, 1,366I, 1,367D
CDD
cd14004 (STKc_PASK)

1,367D

polypeptide substrate binding site
1,205A, 1,290D, 1,292F, 1,329D, 1,331K, 1,333E, 1,350S, 1,364G, 1,365T, 1,366I, 1,367D
CDD
cd14004 (STKc_PASK)
activation loop (A...

1,346I

activation loop (A-loop)
1,346I, 1,347D, 1,348F, 1,349G, 1,350S, 1,351S, 1,352A, 1,353F, 1,354I, 1,355K, 1,356Q, 1,357G, 1,358P, 1,359F, 1,360D, 1,361V, 1,362F, 1,363V, 1,364G, 1,365T, 1,366I, 1,367D
CDD
cd14004 (STKc_PASK)

1,347D

activation loop (A-loop)
1,346I, 1,347D, 1,348F, 1,349G, 1,350S, 1,351S, 1,352A, 1,353F, 1,354I, 1,355K, 1,356Q, 1,357G, 1,358P, 1,359F, 1,360D, 1,361V, 1,362F, 1,363V, 1,364G, 1,365T, 1,366I, 1,367D
CDD
cd14004 (STKc_PASK)

1,348F

activation loop (A-loop)
1,346I, 1,347D, 1,348F, 1,349G, 1,350S, 1,351S, 1,352A, 1,353F, 1,354I, 1,355K, 1,356Q, 1,357G, 1,358P, 1,359F, 1,360D, 1,361V, 1,362F, 1,363V, 1,364G, 1,365T, 1,366I, 1,367D
CDD
cd14004 (STKc_PASK)

1,349G

activation loop (A-loop)
1,346I, 1,347D, 1,348F, 1,349G, 1,350S, 1,351S, 1,352A, 1,353F, 1,354I, 1,355K, 1,356Q, 1,357G, 1,358P, 1,359F, 1,360D, 1,361V, 1,362F, 1,363V, 1,364G, 1,365T, 1,366I, 1,367D
CDD
cd14004 (STKc_PASK)

1,350S

activation loop (A-loop)
1,346I, 1,347D, 1,348F, 1,349G, 1,350S, 1,351S, 1,352A, 1,353F, 1,354I, 1,355K, 1,356Q, 1,357G, 1,358P, 1,359F, 1,360D, 1,361V, 1,362F, 1,363V, 1,364G, 1,365T, 1,366I, 1,367D
CDD
cd14004 (STKc_PASK)

1,351S

activation loop (A-loop)
1,346I, 1,347D, 1,348F, 1,349G, 1,350S, 1,351S, 1,352A, 1,353F, 1,354I, 1,355K, 1,356Q, 1,357G, 1,358P, 1,359F, 1,360D, 1,361V, 1,362F, 1,363V, 1,364G, 1,365T, 1,366I, 1,367D
CDD
cd14004 (STKc_PASK)

1,352A

activation loop (A-loop)
1,346I, 1,347D, 1,348F, 1,349G, 1,350S, 1,351S, 1,352A, 1,353F, 1,354I, 1,355K, 1,356Q, 1,357G, 1,358P, 1,359F, 1,360D, 1,361V, 1,362F, 1,363V, 1,364G, 1,365T, 1,366I, 1,367D
CDD
cd14004 (STKc_PASK)

1,353F

activation loop (A-loop)
1,346I, 1,347D, 1,348F, 1,349G, 1,350S, 1,351S, 1,352A, 1,353F, 1,354I, 1,355K, 1,356Q, 1,357G, 1,358P, 1,359F, 1,360D, 1,361V, 1,362F, 1,363V, 1,364G, 1,365T, 1,366I, 1,367D
CDD
cd14004 (STKc_PASK)

1,354I

activation loop (A-loop)
1,346I, 1,347D, 1,348F, 1,349G, 1,350S, 1,351S, 1,352A, 1,353F, 1,354I, 1,355K, 1,356Q, 1,357G, 1,358P, 1,359F, 1,360D, 1,361V, 1,362F, 1,363V, 1,364G, 1,365T, 1,366I, 1,367D
CDD
cd14004 (STKc_PASK)

1,355K

activation loop (A-loop)
1,346I, 1,347D, 1,348F, 1,349G, 1,350S, 1,351S, 1,352A, 1,353F, 1,354I, 1,355K, 1,356Q, 1,357G, 1,358P, 1,359F, 1,360D, 1,361V, 1,362F, 1,363V, 1,364G, 1,365T, 1,366I, 1,367D
CDD
cd14004 (STKc_PASK)

1,356Q

activation loop (A-loop)
1,346I, 1,347D, 1,348F, 1,349G, 1,350S, 1,351S, 1,352A, 1,353F, 1,354I, 1,355K, 1,356Q, 1,357G, 1,358P, 1,359F, 1,360D, 1,361V, 1,362F, 1,363V, 1,364G, 1,365T, 1,366I, 1,367D
CDD
cd14004 (STKc_PASK)

1,357G

activation loop (A-loop)
1,346I, 1,347D, 1,348F, 1,349G, 1,350S, 1,351S, 1,352A, 1,353F, 1,354I, 1,355K, 1,356Q, 1,357G, 1,358P, 1,359F, 1,360D, 1,361V, 1,362F, 1,363V, 1,364G, 1,365T, 1,366I, 1,367D
CDD
cd14004 (STKc_PASK)

1,358P

activation loop (A-loop)
1,346I, 1,347D, 1,348F, 1,349G, 1,350S, 1,351S, 1,352A, 1,353F, 1,354I, 1,355K, 1,356Q, 1,357G, 1,358P, 1,359F, 1,360D, 1,361V, 1,362F, 1,363V, 1,364G, 1,365T, 1,366I, 1,367D
CDD
cd14004 (STKc_PASK)

1,359F

activation loop (A-loop)
1,346I, 1,347D, 1,348F, 1,349G, 1,350S, 1,351S, 1,352A, 1,353F, 1,354I, 1,355K, 1,356Q, 1,357G, 1,358P, 1,359F, 1,360D, 1,361V, 1,362F, 1,363V, 1,364G, 1,365T, 1,366I, 1,367D
CDD
cd14004 (STKc_PASK)

1,360D

activation loop (A-loop)
1,346I, 1,347D, 1,348F, 1,349G, 1,350S, 1,351S, 1,352A, 1,353F, 1,354I, 1,355K, 1,356Q, 1,357G, 1,358P, 1,359F, 1,360D, 1,361V, 1,362F, 1,363V, 1,364G, 1,365T, 1,366I, 1,367D
CDD
cd14004 (STKc_PASK)

1,361V

activation loop (A-loop)
1,346I, 1,347D, 1,348F, 1,349G, 1,350S, 1,351S, 1,352A, 1,353F, 1,354I, 1,355K, 1,356Q, 1,357G, 1,358P, 1,359F, 1,360D, 1,361V, 1,362F, 1,363V, 1,364G, 1,365T, 1,366I, 1,367D
CDD
cd14004 (STKc_PASK)

1,362F

activation loop (A-loop)
1,346I, 1,347D, 1,348F, 1,349G, 1,350S, 1,351S, 1,352A, 1,353F, 1,354I, 1,355K, 1,356Q, 1,357G, 1,358P, 1,359F, 1,360D, 1,361V, 1,362F, 1,363V, 1,364G, 1,365T, 1,366I, 1,367D
CDD
cd14004 (STKc_PASK)

1,363V

activation loop (A-loop)
1,346I, 1,347D, 1,348F, 1,349G, 1,350S, 1,351S, 1,352A, 1,353F, 1,354I, 1,355K, 1,356Q, 1,357G, 1,358P, 1,359F, 1,360D, 1,361V, 1,362F, 1,363V, 1,364G, 1,365T, 1,366I, 1,367D
CDD
cd14004 (STKc_PASK)

1,364G

activation loop (A-loop)
1,346I, 1,347D, 1,348F, 1,349G, 1,350S, 1,351S, 1,352A, 1,353F, 1,354I, 1,355K, 1,356Q, 1,357G, 1,358P, 1,359F, 1,360D, 1,361V, 1,362F, 1,363V, 1,364G, 1,365T, 1,366I, 1,367D
CDD
cd14004 (STKc_PASK)

1,365T

activation loop (A-loop)
1,346I, 1,347D, 1,348F, 1,349G, 1,350S, 1,351S, 1,352A, 1,353F, 1,354I, 1,355K, 1,356Q, 1,357G, 1,358P, 1,359F, 1,360D, 1,361V, 1,362F, 1,363V, 1,364G, 1,365T, 1,366I, 1,367D
CDD
cd14004 (STKc_PASK)

1,366I

activation loop (A-loop)
1,346I, 1,347D, 1,348F, 1,349G, 1,350S, 1,351S, 1,352A, 1,353F, 1,354I, 1,355K, 1,356Q, 1,357G, 1,358P, 1,359F, 1,360D, 1,361V, 1,362F, 1,363V, 1,364G, 1,365T, 1,366I, 1,367D
CDD
cd14004 (STKc_PASK)

1,367D

activation loop (A-loop)
1,346I, 1,347D, 1,348F, 1,349G, 1,350S, 1,351S, 1,352A, 1,353F, 1,354I, 1,355K, 1,356Q, 1,357G, 1,358P, 1,359F, 1,360D, 1,361V, 1,362F, 1,363V, 1,364G, 1,365T, 1,366I, 1,367D
CDD
cd14004 (STKc_PASK)

Protein sequence

>MCA_02218_1
MQNAISSMTSSDNRDDTNDSQSSKLKQPRRRPSFHIETSSDEEEEEELEFSAPSNTNPSTSPSATKPSSSSSLSNTTKIN
NTPYTPPYNARQPNSRQYSATHMGFRSVSSSSATSRSNAYLSSHLNNQRKPANLATPNTSASSFSLQQPPPPASSNTLAL
NEDLVKQFSSESLHSFSYAFISQNSISSRLDILKRSLEFLRDNPSLTNLSHFPSTSSTTALEGFFKPKQRPQAFRNQIRS
SASSAALSMLANYPNIKNNQASSGNNDSSNNDSLSSSIKNIISSDSQFSKTSVIPGILGTNTGEPMHTLFDNNLKSILIL
LENAHVFPPSVAEASISPYSSTPKTSSASSSNSKLYSLLHETNTAQPSTPFRPIISRSATNPPLLLNSESSEKTNSISTS
AIPETPLEASFESEQNNNNNNKPTLLEPARLRKRTKTNIATFHLQTQLLDALATPYYDPSWNNLIQRSGASVPTISTSMS
TVDLKSAGMRNTSVYSSASSIIHPLSSRFTTNQAVFTTASTAPYLILASNDISCLVFGMSKAEIRRQHIADIIGPDFRDF
VMKRATDSSPNTTFLCGELVPITKFNGQTGLASFFAKKYNSGIIAWVIEEIAHDKAHIEIDLQTGEFSLSGPQKDVLFPF
IDQRKNSLKLHDILSGIPDDLHVLAERLRNDRCLMENHVTISGNTIVPCLIQTSDNFESQATSSSTSNKDGNTTDGEANK
DSSGNSLQKLSVQLISIPHISGVILLNPSDGMKIVDYNSSVLQQLFGYSILDPKHCVGWCIDELIPNFTNYVKKIEETCQ
LDLKGYSSPGLVIPEHLFRKVAVTFAMNNTTNNEKQKSTTNLNEEEEDPDTIMSTPTSFNTPTLEGVSSSPTKDNSSNPQ
LPRSKSKSNSSSETLNQMDIDNENESSKAQIPLNGSAFDLGDDNFMPKKQMDNISAFMASKGIEGQHKDGVFITLDVQMR
IIGNGYAALWVTYSRNITGQQETNQMPSQLSLLSSKKNLHKRLKKSVSSAHHSSNSSTGSEITSPGGHPEGSGHHSSAST
QSGSSSISLSSLSDPTARSRSGSEANNISSPVATKSKEETSEQQPATPTKASSPIDIKPSSSSSSSPSTENASSSVNNVN
NTSVTPKSKSAGSASESANDSNSGSLTHVDFSNINTPRSQVLSPNGEVPNSASSLYSIHIPELGARRREKKLSDFKILKK
MGEGAYGKVILVEYKAEPHLKIVIKSIFKERILVDTWTRDRKLGSIPSEIKVMAVLNKWPHENIIKLLDFFEDDDYFHIE
LEPHGDPGIDLFDLIEMQGDLTEEQCKFLFKQVVSAVRHLHHHDIVHRDIKDENVIVDGEGIAKLIDFGSSAFIKQGPFD
VFVGTIDYAAPEVLAGKPYEGKPQDIWALGILLYTIIYKENPFYNVDEIMEKDLRIPFAMSEESLDLTKLILTRDIHKRP
TVDDIWNHPWLQDSSSDS

GO term prediction

Biological Process

GO:0006468 protein phosphorylation

Molecular Function

GO:0004672 protein kinase activity
GO:0005524 ATP binding

Cellular Component