Protein

MIA_04014_1

Length
429 amino acids

Browser: contig05:507503-509039+

Protein function

EGGNOG:0PIQ3ISN1IMP-specific 5'-nucleotidase involved in IMP (inositol monophosphate) degradation (By similarity)
SGD closest match:S000005681ISN1IMP-specific 5'-nucleotidase 1
CGD closest match:CAL0000179159ISN1IMP-specific 5'-nucleotidase 1

Protein alignments

%idAln lengthE-value
A0A0J9XJD4_GEOCN63.357%4230.0IMP-specific 5'-nucleotidase 1 OS=Geotrichum candidum GN=BN980_GECA20s01792g PE=3 SV=1
A0A060TFD2_BLAAD60.900%4220.0IMP-specific 5'-nucleotidase 1 OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D14520g PE=3 SV=1
A0A1E3PSH4_9ASCO60.706%4258.71e-179IMP-specific 5'-nucleotidase 1 OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_72613 PE=3 SV=1
ISN1_YARLI55.792%4237.78e-166IMP-specific 5'-nucleotidase 1 OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=ISN1 PE=3 SV=1
UniRef50_Q6C67355.792%4231.80e-162IMP-specific 5'-nucleotidase 1 n=11 Tax=Saccharomycetales TaxID=4892 RepID=ISN1_YARLI
A0A1E4THH8_9ASCO55.504%4272.31e-140Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_2922 PE=4 SV=1
ISN1_CANAL49.893%4675.62e-148IMP-specific 5'-nucleotidase 1 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=ISN1 PE=3 SV=1
ISN1_YEAST47.930%4591.45e-132IMP-specific 5'-nucleotidase 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ISN1 PE=1 SV=1
MCA_02210_153.429%3503.50e-122MCA_02210_1
A0A167FGB2_9ASCO60.428%1871.08e-77IMP 5'-nucleotidase OS=Sugiyamaella lignohabitans GN=ISN1 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.2796
Predicted cleavage: 15

Protein family membership

Domains and repeats

  1. Domain
1 50 100 150 200 250 300 350 400 429

Detailed signature matches

  1. Family IPR009453
    IMP-specific 5-nucleotidase
    1. PF06437 (ISN1)
    2. PIRSF028836 (ISN1)
  2. Domain IPR023214
    HAD-like domain
    1. SSF56784 (HAD-like)
    2. G3DSA:3.40.50...

Protein sequence

>MIA_04014_1
MTSRQVSFSNSSRYRVEXPTGTLLTCLDALKTHRRDEFIEWIKGLLVVPFVLHAGPTVNEMKTVDISQARYAEIFRDVEQ
LIRDQIYMDAQGLPHLSRLRALVPSIGTFFTELPLEQAFLVQDPKRAISARRLVSPSFNDIRLILNTAQAMALSQGRHPL
KLVTFDGDVTLYDDGMSLLKDDPVVARLIKLLAQNLHVGIVTAAGYPEKSGENYILRLKGLVEAIHESTELSADQKNNVY
VMGGESNYLFRLKGSEAELEWIDPRDWTVAEVAKWQESDMCELLDTAQSVLSHSRAHMNLQDSTVIVRKKRGVGLVPRAG
HVICREVLEEVVLTAQRRLETTAVANRISFSAFNGGHDVWVDIGDKRLGVLSLRRYLGAIEGNQALHVGDQFASVGANDF
KARMAACTVWIASPRETVDIMDELLEYLG

GO term prediction

Biological Process

GO:0006190 inosine salvage
GO:0009117 nucleotide metabolic process

Molecular Function

GO:0000287 magnesium ion binding
GO:0050483 IMP 5'-nucleotidase activity

Cellular Component

None predicted.