Protein

MCA_02210_1

Length
563 amino acids

Gene name: ISN1

Description: IMP-specific 5'-nucleotidase 1

Browser: contigB:609551-611843-

RNA-seq: read pairs 4895, FPKM 107.2, percentile rank 80.0% (100% = highest expression)

Protein function

Annotation:ISN1IMP-specific 5'-nucleotidase 1
KEGG:K18550ISN1 IMP and pyridine-specific 5'-nucleotidase [EC:3.1.3.99 3.1.3.-]
EGGNOG:0PIQ3ISN1IMP-specific 5'-nucleotidase involved in IMP (inositol monophosphate) degradation (By similarity)
SGD closest match:S000005681ISN1IMP-specific 5'-nucleotidase 1
CGD closest match:CAL0000179159ISN1IMP-specific 5'-nucleotidase 1

Protein alignments

%idAln lengthE-value
A0A0J9XJD4_GEOCN51.55%3888e-115IMP-specific 5'-nucleotidase 1 OS=Geotrichum candidum GN=BN980_GECA20s01792g PE=3 SV=1
MIA_04014_153.43%3502e-114MIA_04014_1
ISN1_YARLI51.59%3454e-104IMP-specific 5'-nucleotidase 1 OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=ISN1 PE=3 SV=1
UniRef50_Q6C67351.59%3451e-100IMP-specific 5'-nucleotidase 1 n=11 Tax=Saccharomycetales TaxID=4892 RepID=ISN1_YARLI
A0A1E3PSH4_9ASCO50.29%3502e-102IMP-specific 5'-nucleotidase 1 OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_72613 PE=3 SV=1
A0A060TFD2_BLAAD51.02%3432e-101IMP-specific 5'-nucleotidase 1 OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D14520g PE=3 SV=1
ISN1_CANAL48.77%3655e-98IMP-specific 5'-nucleotidase 1 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=ISN1 PE=3 SV=1
ISN1_YEAST44.05%4205e-90IMP-specific 5'-nucleotidase 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ISN1 PE=1 SV=1
A0A1E4THH8_9ASCO48.39%3411e-76Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_2922 PE=4 SV=1
A0A167FGB2_9ASCO67.47%831e-34IMP 5'-nucleotidase OS=Sugiyamaella lignohabitans GN=ISN1 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.1282

Protein family membership

Domains and repeats

  1. Domain
1 100 200 300 400 500 563

Detailed signature matches

  1. Family IPR009453
    IMP-specific 5-nucleotidase
    1. PF06437 (ISN1)
  2. Domain IPR023214
    HAD-like domain
    1. SSF56784 (HAD-like)
    2. G3DSA:3.40.50...
Unintegrated signatures no IPR
Unintegrated signatures
  1. Coil
  2. mobidb-lite (disord...)

Protein sequence

>MCA_02210_1
MASRYRVEYALKTHRRDELIEWIKGLLAVPFVLHAGRRSIEDNRSIVLSKYAEVFKDVEALIADKVEMDSLNTPDLPRLN
QLVPSVGLFFTPLPLEEAFLIQDKKRAISSRKLVSPSFNDIRVILNTAQVLQLAKYGSGNEGSKSLKLVTFDGDVTLYDD
GHNLDINDPVVERLLDLLSRDIYIGIVTAAGYSDISGKEYEVRLKGLIDAINDPEKSSRLTQKQKSNVYVMGGESNFLFQ
LLPSPSQPGNKNQEYHFTWIDYDRWQLPQVKNWDPQQLEQLLEKAQEILTQFQKNLELQNNTLIIRKERGVGIIPKPGYS
ICRELLEEIVLNTQVQLETYLNSKIYHNLTTPGSSNEFGHHVGILSPHLTPNDGSVRRRRELLHVSAYSRHRSSPSPSPA
PQLGSRGDSSGSLQQQQSRIEKLKLDNTLNEFDSSRNNIEEINSSSDDEEPDSGKKPAATTTGDKAKPVSLGGDAICFSA
FNGGRDVWVDIGDKKLGVMSLQKYLGDLSGVETLHVGDQFASVGANDFKARMAGCTVWIASPQETVEVMDELLTYMEDQK
REF

GO term prediction

Biological Process

GO:0006190 inosine salvage
GO:0009117 nucleotide metabolic process

Molecular Function

GO:0000287 magnesium ion binding
GO:0050483 IMP 5'-nucleotidase activity

Cellular Component

None predicted.