Protein

MIA_04008_1

Length
454 amino acids

Browser: contig05:485624-486989+

Protein function

EGGNOG:0PFMAPMI1mannose-6-phosphate isomerase
SGD closest match:S000000805PMI40Mannose-6-phosphate isomerase
CGD closest match:CAL0000189115PMI1Mannose-6-phosphate isomerase

Protein alignments

%idAln lengthE-value
MCA_02204_170.796%4520.0MCA_02204_1
A0A0J9X4H0_GEOCN58.515%4583.24e-178Mannose-6-phosphate isomerase OS=Geotrichum candidum GN=BN980_GECA01s09426g PE=3 SV=1
A0A060T5V6_BLAAD58.929%4482.06e-171Mannose-6-phosphate isomerase OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C08404g PE=3 SV=1
A0A1E3PCP7_9ASCO55.876%4519.85e-168Mannose-6-phosphate isomerase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_84380 PE=3 SV=1
MPI_CANAL56.637%4521.00e-163Mannose-6-phosphate isomerase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=PMI1 PE=1 SV=2
UniRef50_A0A1X7QWL554.382%4455.19e-156Similar to Saccharomyces cerevisiae YER003C PMI40 Mannose-6-phosphate isomerase, catalyzes the interconversion of fructose-6-P and mannose-6-P n=1 Tax=Kazachstania saulgeensis TaxID=1789683 RepID=A0A1X7QWL5_9SACH
Q6CE59_YARLI54.036%4463.77e-158Mannose-6-phosphate isomerase OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_B18348g PE=3 SV=1
MPI_YEAST54.933%4462.48e-156Mannose-6-phosphate isomerase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PMI40 PE=1 SV=4
A0A167E236_9ASCO57.834%4341.20e-154Mannose-6-phosphate isomerase OS=Sugiyamaella lignohabitans GN=PMI40 PE=3 SV=1
A0A1E4TLH2_9ASCO52.513%3984.44e-127Mannose-6-phosphate isomerase OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_1207 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0099

Protein family membership

Domains and repeats

  1. Domain
1 50 100 150 200 250 300 350 400 454

Detailed signature matches

  1. Family IPR001250
    Mannose-6-phosphate isomerase, type I
    1. TIGR00218
    2. PF01238 (PMI_typeI)
  2. Family IPR016305
    Mannose-6-phosphate isomerase
    1. PR00714 (MAN6PISMRASE)
    2. PIRSF001480 (PMI)
  3. Domain IPR014710
    RmlC-like jelly roll fold
    1. G3DSA:2.60.12...
  4. Domain IPR011051
    RmlC-like cupin domain
    1. SSF51182 (RmlC-like...)
  5. SITE IPR018050
    Phosphomannose isomerase, type I, conserved site
    1. PS00966 (PMI_I_2)
    2. PS00965 (PMI_I_1)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:1.10.44...

Protein sequence

>MIA_04008_1
MSQSDFDLVKLQCGVQTYDWGKLGKSSAVAQFAESADPEFKTDPSKPYAELWMGTHPSVPSIAISSSAPPISLRSVLSKY
PTLLGDRITAKFGPGELPFLFKVLSIRKALSIQAHPDKALGRQLHAADPKNYPDDNHKPEMAIAITDFEGFCGFRPLAEI
SALLKNIPEFVELIGGQKSADEFINGYKELLPSDQEGSPDDVSNRKALQDLFSKVMNAPQSIVSKLTVALVERASSEQEK
FGFNIDPSYKGSFGKPLADLIIRLNEQFPEDIGLFCGGLMLNYVALKSGEAMFLRAKDPHAYISGDIIECMAASDNVVRA
GFTPKFKDVPNLVSMLTYSYDPVEKQKMVPEPYPLSQSSSDSVKNTLFNPPIDEFAVVQTILPKKGDSTTLQALDGPSII
LITEGTAKLNNKTTTLEFPRGQVAFIGAGTAVELTNTGDDEVVTYTAIVEVSPA

GO term prediction

Biological Process

GO:0005975 carbohydrate metabolic process
GO:0009298 GDP-mannose biosynthetic process

Molecular Function

GO:0004476 mannose-6-phosphate isomerase activity
GO:0008270 zinc ion binding

Cellular Component

None predicted.