Protein

MIA_03939_1

Length
878 amino acids

Browser: contig05:317205-319842+

Protein function

EGGNOG:0PH2JPGUG_05450dna repair helicase
SGD closest match:S000001405SSL2DNA repair helicase RAD25
CGD closest match:CAL0000180210CAALFM_CR02970CATFIIH/NER complex ATPase/helicase subunit

Protein alignments

%idAln lengthE-value
A0A0J9XCB1_GEOCN78.973%8370.0Similar to Saccharomyces cerevisiae YIL143C SSL2 Component of the holoenzyme form of RNA polymerase transcription factor TFIIH OS=Geotrichum candidum GN=BN980_GECA07s05312g PE=4 SV=1
MCA_02128_179.042%8350.0MCA_02128_1
A0A161HHK9_9ASCO79.140%7670.0TFIIH/NER complex ATPase/helicase subunit SSL2 OS=Sugiyamaella lignohabitans GN=SSL2 PE=4 SV=1
Q6CEZ1_YARLI78.718%7800.0YALI0B11726p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_B11726g PE=4 SV=1
A0A060T6S9_BLAAD74.163%8360.0ARAD1C22748p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C22748g PE=4 SV=1
A0A1D8PSC6_CANAL73.482%8070.0TFIIH/NER complex ATPase/helicase subunit OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=CAALFM_CR02970CA PE=4 SV=1
UniRef50_A0A1X7QY0875.288%7810.0Similar to Saccharomyces cerevisiae YIL143C SSL2 Component of the holoenzyme form of RNA polymerase transcription factor TFIIH n=1 Tax=Kazachstania saulgeensis TaxID=1789683 RepID=A0A1X7QY08_9SACH
RAD25_YEAST73.913%7820.0DNA repair helicase RAD25 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SSL2 PE=1 SV=1
A0A1E4T9W4_9ASCO73.779%7780.0Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_28840 PE=4 SV=1
A0A1E3PRF6_9ASCO88.868%5210.0DNA repair helicase rad25 OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_49857 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.4225

Protein family membership

Domains and repeats

  1. Domain
  2. Domain
  3. Domain
1 100 200 300 400 500 600 700 800 878

Detailed signature matches

  1. Family IPR001161
    Helicase XPB/Ssl2
    1. TIGR00603
  2. Domain IPR032830
    Helicase XPB/Ssl2, N-terminal domain
    1. PF13625 (Helicase_C_3)
  3. Domain IPR027417
    P-loop containing nucleoside triphosphate hydrolase
    1. SSF52540 (P-loop co...)
  4. Domain IPR014001
    Helicase superfamily 1/2, ATP-binding domain
    1. PS51192 (HELICASE_A...)
    2. SM00487 (ultradead3)
  5. Domain IPR006935
    Helicase/UvrB, N-terminal
    1. PF04851 (ResIII)
  6. Domain IPR032438
    ERCC3/RAD25/XPB helicase, C-terminal domain
    1. PF16203 (ERCC3_RAD25_C)
  7. Domain IPR001650
    Helicase, C-terminal
    1. PS51194 (HELICASE_CTER)
    2. SM00490 (helicmild6)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:3.40.50...
  2. PR00851 (XRODRMPGMNTB)
  3. cd00046 (DEXDc)
  4. cd00079 (HELICc)
  5. mobidb-lite (disord...)

Residue annotation

  1. ATP binding site c...
  2. putative Mg++ bind...
  3. nucleotide binding...
  4. ATP-binding site c...

Protein sequence

>MIA_03939_1
MARTQAAGTKRAIDQVAYNYDSNSTNTTSSEDEGELEDLPKIPKVRLKIGSSNVVEVRNSNSTLGSDKGTVDELDEDNSS
NAAKIAAARSVEGGAERTADFQPDSVSSFFGKNDFSYLKLKPDHSARPLWINPDDGRIILESFSPLAEQAQDFLVTIAEP
VSRPTFIHEYRLTTYSLYAAVSVGLQTKDIISVLNRLSKVPVPKTIVKFINDCTLSYGKIRLVLKHNRYFLESSQADVLQ
MLLKDREIGPLRIEASETTTKDGLVTEKAPTMSGLVIPGTKPLNANNTTTNGDTNSSANSNTAGANESSDVPPGAKEIPD
DPEAAFNAVLSLDGEDDDDLDAVHSFEVSSSSVETVKKRCQEIDFPVLEEYDFRNDKQNVDLNIDLKPSTQIRPYQEKSL
SKMFGNGRARSGIIVLPCGAGKTLVGITAACTIRKSVIVLCTSSVSVYQWRQQFLQWCTIQPEDVAVFTSENKEKFRGEA
GLVVSTYSMVANTRNRSHDSQKMMDFLTSREWGFIILDEVHVVPAAMFRRVVTTIAAHAKLGLTATLLREDDKIDDLNFL
IGPKLYEANWMDLSQKGHIANVQCAEVWCPMTSEFYQEYLNVNARKRMLLYIMNPSKFQACQFLIQYHEKRGDKIIVFSD
NVYALEAYAYKLGKPFIHGATPQHERMKILSNFQFNSEINTMFLSKVGDTSIDLPEATCLIQISSHYGSRRQEAQRLGRI
LRAKRRNDEGFNAFFYSLVSKDTQEMYYSTKRQAFLVDQGYAFKVITHLHGMDKLPDLAYSTAGERRELLQAVLLANESL
AGLETGDDAENSVGRSGNVISKRHKGGSKANRVVGSLSALAGGEDMAYVEYNKSKNKDLKKTGSNLIHKLYYKKKKPA

GO term prediction

Biological Process

GO:0006289 nucleotide-excision repair
GO:0006367 transcription initiation from RNA polymerase II promoter

Molecular Function

GO:0003677 DNA binding
GO:0004003 ATP-dependent DNA helicase activity
GO:0005524 ATP binding
GO:0016787 hydrolase activity

Cellular Component

None predicted.