MCA_02128_1
Gene name: SSL2
Description: DNA repair helicase RAD25, component of RNA polymerase transcription factor TFIIH holoenzyme
Browser: contigB:312945-315492+
RNA-seq: read pairs 465, FPKM 6.8, percentile rank 20.2% (100% = highest expression)
Protein function
| Annotation: | SSL2 | DNA repair helicase RAD25, component of RNA polymerase transcription factor TFIIH holoenzyme | |
|---|---|---|---|
| KEGG: | K10843 | ERCC3 | DNA excision repair protein ERCC-3 [EC:3.6.4.12] |
| EGGNOG: | 0PH2J | PGUG_05450 | dna repair helicase |
| SGD closest match: | S000001405 | SSL2 | DNA repair helicase RAD25 |
| CGD closest match: | CAL0000180210 | CAALFM_CR02970CA | TFIIH/NER complex ATPase/helicase subunit |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MIA_03939_1 | 80.15% | 821 | 0.0 | MIA_03939_1 |
| A0A0J9XCB1_GEOCN | 80.48% | 799 | 0.0 | Similar to Saccharomyces cerevisiae YIL143C SSL2 Component of the holoenzyme form of RNA polymerase transcription factor TFIIH OS=Geotrichum candidum GN=BN980_GECA07s05312g PE=4 SV=1 |
| A0A1E3PRF6_9ASCO | 78.90% | 801 | 0.0 | DNA repair helicase rad25 OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_49857 PE=4 SV=1 |
| A0A161HHK9_9ASCO | 81.31% | 749 | 0.0 | TFIIH/NER complex ATPase/helicase subunit SSL2 OS=Sugiyamaella lignohabitans GN=SSL2 PE=4 SV=1 |
| Q6CEZ1_YARLI | 76.71% | 803 | 0.0 | YALI0B11726p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_B11726g PE=4 SV=1 |
| A0A060T6S9_BLAAD | 78.50% | 758 | 0.0 | ARAD1C22748p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C22748g PE=4 SV=1 |
| A0A1D8PSC6_CANAL | 76.55% | 759 | 0.0 | TFIIH/NER complex ATPase/helicase subunit OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=CAALFM_CR02970CA PE=4 SV=1 |
| UniRef50_A0A1X7QY08 | 75.66% | 760 | 0.0 | Similar to Saccharomyces cerevisiae YIL143C SSL2 Component of the holoenzyme form of RNA polymerase transcription factor TFIIH n=1 Tax=Kazachstania saulgeensis TaxID=1789683 RepID=A0A1X7QY08_9SACH |
| RAD25_YEAST | 75.53% | 760 | 0.0 | DNA repair helicase RAD25 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SSL2 PE=1 SV=1 |
| A0A1E4T9W4_9ASCO | 74.50% | 757 | 0.0 | Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_28840 PE=4 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.5278
Protein family membership
- Helicase XPB/Ssl2 (IPR001161)
Domains and repeats
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Domain
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Domain
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Domain
Detailed signature matches
no IPR
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PR00851 (XRODRMPGMNTB)
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cd00046 (DEXDc)
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cd00079 (HELICc)
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mobidb-lite (disord...)
Residue annotation
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ATP binding site c...
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putative Mg++ bind...
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nucleotide binding...
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ATP-binding site c...
Protein sequence
>MCA_02128_1 MVRATLRKIEDDSDSSNTSYSEEEEEELDEYPVIPKVRLRIGANNDNNDDNNSQPKAVTAGGGEDNERLGDFQADSVSQM FGKNDFSYLKLKPDHASRPLWINPDDGRIILESFSPLAEQAQDFLVTIAEPVSRPTYIHEYRLTTYSLYAAVSVGLETKD IISVLSRLSKVPVPKSIIKFIGDCTVSYGKIKLVLKHNRYFVESSHADILQTLLKDPEIGPLRLEASETTTRDGLVTEKA PRIGNLVIPGTKPQGKNGEASDSKLSDGGNENKQGGGDEVADKTAMDEAEAAFQAVVGLDKDDDDDLDAVHSFEISASSV ETVKKRCQEIDFPVLEEYDFRNDKQNKDLEIDLKPSTQIRPYQEKSLSKMFGNGRARSGIIVLPCGAGKTLVGITAACTI RKSIIVLCTSSVSVYQWRDQFLKWCTIPPEKVAVFTSENKEKFDSESGLVVSTYSMVANTRNRSHDSQKMMDFLTSREWG LIILDEVHVVPAAMFRRVVTTIAAHAKLGLTATLLREDDKIGDLNFLIGPKLYEANWMDLSQQGHIANVQCAEVWCPMTS EFYQQYLSANARKRMLLYIMNPTKFQACQFLINYHEKRGDHIIVFSDNVYALQQYATKLGVPFIDGSTPQHERMKILSNF QNNEAVKTIFLSKVGDTSIDLPEATCLIQISSHYGSRRQEAQRLGRILRAKRRNDEGFNAFFYSLVSKDTQEMYYSTKRQ AFLVDQGYAFKVITHLHGMEKLPNLAYSTPREQRELLQEVLLQNENASSLEAGDDADNSVGRGSAVVHKRHKFGSKANRV VGKMSSLAGGEDMAYVEYNKNRNKELKKSGSSIINKIYYKKKKVSTPF
GO term prediction
Biological Process
GO:0006289 nucleotide-excision repair
GO:0006367 transcription initiation from RNA polymerase II promoter
Molecular Function
GO:0003677 DNA binding
GO:0004003 ATP-dependent DNA helicase activity
GO:0005524 ATP binding
GO:0016787 hydrolase activity
Cellular Component
None predicted.