Protein

MIA_03922_1

Length
564 amino acids

Browser: contig05:269939-271634-

Protein function

EGGNOG:0PGCYDCD1Deoxycytidylate deaminase
SGD closest match:S000001187DCD1Deoxycytidylate deaminase
CGD closest match:CAL0000182387orf19.7243Deoxycytidine monophosphate deaminase

Protein alignments

%idAln lengthE-value
MCA_04540_144.165%4374.11e-104MCA_04540_1
UniRef50_B9WA4748.624%3275.96e-98Deoxycytidylate deaminase (DCMP deaminase), putative n=18 Tax=Saccharomycetales TaxID=4892 RepID=B9WA47_CANDC
A0A060T2K9_BLAAD49.682%3144.13e-101ARAD1A09240p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1A09240g PE=4 SV=1
A0A1D8PFW6_CANAL48.408%3145.06e-100Deoxycytidine monophosphate deaminase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.7243 PE=4 SV=1
A0A1E3PIY7_9ASCO48.910%3211.42e-98Uncharacterized protein (Fragment) OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_8440 PE=4 SV=1
A0A167CVB6_9ASCO44.343%3277.12e-92Dcd1p OS=Sugiyamaella lignohabitans GN=DCD1 PE=4 SV=1
A0A0J9XFX1_GEOCN45.570%3161.04e-86Similar to Saccharomyces cerevisiae YHR144C DCD1 Deoxycytidine monophosphate (DCMP) deaminase required for dCTP and dTTP synthesis OS=Geotrichum candidum GN=BN980_GECA14s00846g PE=4 SV=1
Q6CAZ2_YARLI44.375%3209.12e-85YALI0C23210p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_C23210g PE=4 SV=1
DCTD_YEAST63.855%1661.29e-67Deoxycytidylate deaminase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=DCD1 PE=1 SV=2
A0A1E4THN9_9ASCO62.420%1573.68e-67Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_26779 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0207

Protein family membership

None predicted.

Domains and repeats

  1. Domain
1 100 200 300 400 500 564

Detailed signature matches

  1. Domain IPR016193
    Cytidine deaminase-like
    1. SSF53927 (Cytidine ...)
  2. Domain IPR002125
    Cytidine and deoxycytidylate deaminase domain
    1. PF00383 (dCMP_cyt_d...)
    2. PS51747 (CYT_DCMP_D...)
  3. Domain IPR035105
    Deoxycytidylate deaminase domain
    1. cd01286 (deoxycytid...)
  4. SITE IPR016192
    APOBEC/CMP deaminase, zinc-binding
    1. PS00903 (CYT_DCMP_D...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:3.40.14...
  2. G3DSA:3.40.50...
  3. mobidb-lite (disord...)

Residue annotation

  1. catalytic motif cd...
  2. Zn binding site cd...

Protein sequence

>MIA_03922_1
MLIIVSGNKCSGKTEVANYLMINDYILLELSRQLPLRTPSIPHTLPGYNFDTVGSIGAENDGLIYASKESQASTPRVNSE
EEASKMSKKYLNLLSKNICKQVAQNKTAELQKIKREDTLVNDSDPRQETPTPQRKKTIREMMDELSEDEEVETPTKHQEP
LQDKDSDSEEPKTISAKSSTDELKPTQSITDLIQEMTTSATDEHPINTDSVHPYVYTPEMTNAAPSRLLPIPQPPPPFTM
YKTADGTNKIVFDSIDTLISYVIKNWRDDFVFVLEPGPNAYAQLLKFETIPYSLHVTVEAPIITRWKRFLMKVYGFSFPP
AATKMSRLEDHLTKTLLFNGQSSKSESEESPPVLLERFATESDEIMYDISAGFKPLAAVVDRAKLTIVNSTDTINSLQTK
LNRLDLKNTERLRPSWDLYFMRLAGLAALRSNCMKRRVGCVIVRDNRVIATGYNGTPRGLPNCNEGGCTRCNGGGMSGSN
LDSCLCLHAEENALLEAGRDRVGSSSVIYCNTAPCLTCSIKIVQSGIKEVVYEQAYSGQNSEKIFQQANVVIRQFVPPND
NVAI

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0003824 catalytic activity
GO:0008270 zinc ion binding
GO:0016787 hydrolase activity

Cellular Component

None predicted.