Protein

MCA_04540_1

Length
675 amino acids

Gene name: DCD1

Description: Deoxycytidylate deaminase

Browser: contigC:3318356-3320384+

RNA-seq: read pairs 3318, FPKM 60.6, percentile rank 69.5% (100% = highest expression)

Protein function

Annotation:DCD1Deoxycytidylate deaminase
KEGG:K01493comEB dCMP deaminase [EC:3.5.4.12]
EGGNOG:0PGCYDCD1Deoxycytidylate deaminase
SGD closest match:S000001187DCD1Deoxycytidylate deaminase
CGD closest match:CAL0000182387orf19.7243Deoxycytidine monophosphate deaminase

Protein alignments

%idAln lengthE-value
MIA_03922_152.16%3241e-88MIA_03922_1
A0A167CVB6_9ASCO49.49%2953e-87Dcd1p OS=Sugiyamaella lignohabitans GN=DCD1 PE=4 SV=1
A0A1D8PFW6_CANAL49.50%2992e-84Deoxycytidine monophosphate deaminase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.7243 PE=4 SV=1
UniRef50_B9WA4749.50%2993e-81Deoxycytidylate deaminase (DCMP deaminase), putative n=18 Tax=Saccharomycetales TaxID=4892 RepID=B9WA47_CANDC
A0A060T2K9_BLAAD46.28%2964e-82ARAD1A09240p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1A09240g PE=4 SV=1
A0A1E3PIY7_9ASCO43.13%3134e-79Uncharacterized protein (Fragment) OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_8440 PE=4 SV=1
A0A0J9XFX1_GEOCN44.44%3061e-78Similar to Saccharomyces cerevisiae YHR144C DCD1 Deoxycytidine monophosphate (DCMP) deaminase required for dCTP and dTTP synthesis OS=Geotrichum candidum GN=BN980_GECA14s00846g PE=4 SV=1
Q6CAZ2_YARLI38.87%3378e-69YALI0C23210p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_C23210g PE=4 SV=1
DCTD_YEAST39.93%2984e-59Deoxycytidylate deaminase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=DCD1 PE=1 SV=2
A0A1E4THN9_9ASCO59.75%1597e-56Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_26779 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0045

Protein family membership

None predicted.

Domains and repeats

  1. Domain
1 100 200 300 400 500 600 675

Detailed signature matches

  1. Domain IPR016193
    Cytidine deaminase-like
    1. SSF53927 (Cytidine ...)
  2. Domain IPR002125
    Cytidine and deoxycytidylate deaminase domain
    1. PF00383 (dCMP_cyt_d...)
    2. PS51747 (CYT_DCMP_D...)
  3. Domain IPR035105
    Deoxycytidylate deaminase domain
    1. cd01286 (deoxycytid...)
  4. SITE IPR016192
    APOBEC/CMP deaminase, zinc-binding
    1. PS00903 (CYT_DCMP_D...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:3.40.14...
  2. mobidb-lite (disord...)

Residue annotation

  1. catalytic motif cd...
  2. Zn binding site cd...

Protein sequence

>MCA_04540_1
MLIGISGSYCSGKAEVAKYLQQNGFTLLSYAPQDPQIKTVYSLPLNPPAYEMPNNITGLPVVHTEDISGNLDSISENTSL
FANPASSTSSSQLATQINKVKNLRKSVNNDTISNILAAQSTVSEEEKPSIESSHESKSDDIVKDHSDIGSAEEETPEELD
RKETSSQSMEQMKADDSDDTDSLIDRKIKSKRATLPELMDEFSGDEYNPPTSLDENGKIKMPSPSDPCLTKLSEKHLQSI
DSALEDVKTSSAIFHQSESDNADISEVVSEDESDETTGKQDLRGVSLNKKVLQSLAKKERMGSIKLSKSLSDLIKEMTNT
QWDQNQASSAGIKDTGMAVPFSASYVSPVAQFNRAETFPMYPNYLLASQNNIDPKHTFTSLDQIPPYIIENSSRNFIIII
REIDMIKALESYPFFLHISIDAPIGKRYSRYLHKYQPFNPAVIHTSNPSTPIAPSSTNLMNFQQFVGTSDEYMYSKPNCR
ITAFSKAKLIIINDYDTIGELYITLSKLDLSNTERLRPSWDSYFMRLASLASHRSNCIKRRVGCVIVNDKRVVSTGYNGT
PRGLKNCNEGGCGRCNNFNPKNPSGANLDSCLCLHAEENALLEAGRGRVGENSIIYCNTAPCLTCSIKIVQIGIKEVVYE
IPYSSQQNSQKIFEEANVIFRQFVSPDEGIVLYKP

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0003824 catalytic activity
GO:0008270 zinc ion binding
GO:0016787 hydrolase activity

Cellular Component

None predicted.