MIA_03914_1

Protein

Length

937 amino acids

Protein function

EGGNOG:	0PFP2	DSK1	protein kinase dsk1
SGD closest match:	S000004829	SKY1	Serine/threonine-protein kinase SKY1
CGD closest match:	CAL0000186077	orf19.2436	Serine/threonine protein kinase

Protein alignments

	%id	Aln length	E-value
A0A0J9XJX6_GEOCN	67.630%	519	0.0	Similar to Saccharomyces cerevisiae YMR216C SKY1 SR protein kinase (SRPK) involved in regulating proteins involved in mRNA metabolism and cation homeostasis OS=Geotrichum candidum GN=BN980_GECA26s00659g PE=4 SV=1
A0A060SZX7_BLAAD	66.132%	499	0.0	ARAD1C12122p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C12122g PE=4 SV=1
UniRef50_A0A0J9X7F3	60.913%	504	0.0	Similar to Saccharomyces cerevisiae YMR216C SKY1 SR protein kinase (SRPK) involved in regulating proteins involved in mRNA metabolism and cation homeostasis n=2 Tax=Saccharomycetales TaxID=4892 RepID=A0A0J9X7F3_GEOCN
Q6CGK3_YARLI	61.277%	501	0.0	YALI0A18590p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_A18590g PE=3 SV=2
A0A1E4TK38_9ASCO	60.521%	499	0.0	Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_22954 PE=4 SV=1
MCA_03425_1	80.000%	265	1.08e-136	MCA_03425_1
A0A1E3PGG9_9ASCO	65.000%	260	1.48e-105	Kinase-like protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_52641 PE=4 SV=1
A0A161HKF5_9ASCO	70.085%	234	1.54e-103	Serine/threonine protein kinase SKY1 OS=Sugiyamaella lignohabitans GN=SKY1 PE=4 SV=1
A0A1D8PDS9_CANAL	67.204%	186	8.30e-80	Serine/threonine protein kinase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.2436 PE=4 SV=1
SKY1_YEAST	51.880%	266	5.67e-77	Serine/threonine-protein kinase SKY1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SKY1 PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0019

Protein family membership

None predicted.

Domains and repeats

Domain
459 - 909
Protein kinase-like domain (IPR011009)
Protein kinase domain (IPR000719)

1 100 200 300 400 500 600 700 800 937

Detailed signature matches

IPR011009

Protein kinase-like domain
1. SSF56112 (Protein k...)
  
  459 - 610
  
  SUPERFAMILY
  SSF56112 (Protein kinase-like (PK-like))
  
  738 - 909
  
  SUPERFAMILY
  SSF56112 (Protein kinase-like (PK-like))
IPR000719

Protein kinase domain
1. PS50011 (PROTEIN_KI...)
  
  464 - 904
  
  PROSITE profiles
  PS50011 (PROTEIN_KINASE_DOM)
2. SM00220 (serkin_6)
  
  464 - 904
  
  SMART
  SM00220 (serkin_6)
3. PF00069 (Pkinase)
  
  464 - 607
  
  Pfam
  PF00069 (Pkinase)
  
  745 - 904
  
  Pfam
  PF00069 (Pkinase)
IPR017441

Protein kinase, ATP binding site
1. PS00107 (PROTEIN_KI...)
  
  470 - 494
  
  PROSITE patterns
  PS00107 (PROTEIN_KINASE_ATP)
IPR008271

Serine/threonine-protein kinase, active site
1. PS00108 (PROTEIN_KI...)
  
  594 - 606
  
  PROSITE patterns
  PS00108 (PROTEIN_KINASE_ST)

no IPR

Unintegrated signatures

G3DSA:1.10.51...

548 - 906

GENE3D
G3DSA:1.10.510.10 (G3DSA:1.10.510.10)
G3DSA:3.30.20...

404 - 547

GENE3D
G3DSA:3.30.200.20 (G3DSA:3.30.200.20)
NON_CYTOPLASM... (N...)

30 - 937

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)
SIGNAL_PEPTIDE (Sig...)

1 - 29

PHOBIUS
SIGNAL_PEPTIDE (Signal Peptide)
SIGNAL_PEPTID... (S...)

22 - 29

PHOBIUS
SIGNAL_PEPTIDE_C_REGION (Signal peptide C-region)
SIGNAL_PEPTID... (S...)

10 - 21

PHOBIUS
SIGNAL_PEPTIDE_H_REGION (Signal peptide H-region)
SIGNAL_PEPTID... (S...)

1 - 9

PHOBIUS
SIGNAL_PEPTIDE_N_REGION (Signal peptide N-region)
cd14136 (STKc_SRPK)

452 - 904

CDD
cd14136 (STKc_SRPK)
mobidb-lite (disord...)

301 - 349

MobiDB Lite
mobidb-lite (disorder_prediction)

626 - 664

MobiDB Lite
mobidb-lite (disorder_prediction)

1 - 173

MobiDB Lite
mobidb-lite (disorder_prediction)

371 - 449

MobiDB Lite
mobidb-lite (disorder_prediction)

195 - 270

MobiDB Lite
mobidb-lite (disorder_prediction)

Residue annotation

ATP binding site c...

470L

ATP binding site
470L, 471G, 472W, 473G, 474H, 478V, 492A, 494K, 530V, 550F, 551E, 552V, 553L, 556N, 598D, 600K, 602E, 603N, 605L, 749D
CDD
cd14136 (STKc_SRPK)

471G

ATP binding site
470L, 471G, 472W, 473G, 474H, 478V, 492A, 494K, 530V, 550F, 551E, 552V, 553L, 556N, 598D, 600K, 602E, 603N, 605L, 749D
CDD
cd14136 (STKc_SRPK)

472W

ATP binding site
470L, 471G, 472W, 473G, 474H, 478V, 492A, 494K, 530V, 550F, 551E, 552V, 553L, 556N, 598D, 600K, 602E, 603N, 605L, 749D
CDD
cd14136 (STKc_SRPK)

473G

ATP binding site
470L, 471G, 472W, 473G, 474H, 478V, 492A, 494K, 530V, 550F, 551E, 552V, 553L, 556N, 598D, 600K, 602E, 603N, 605L, 749D
CDD
cd14136 (STKc_SRPK)

474H

ATP binding site
470L, 471G, 472W, 473G, 474H, 478V, 492A, 494K, 530V, 550F, 551E, 552V, 553L, 556N, 598D, 600K, 602E, 603N, 605L, 749D
CDD
cd14136 (STKc_SRPK)

478V

ATP binding site
470L, 471G, 472W, 473G, 474H, 478V, 492A, 494K, 530V, 550F, 551E, 552V, 553L, 556N, 598D, 600K, 602E, 603N, 605L, 749D
CDD
cd14136 (STKc_SRPK)

492A

ATP binding site
470L, 471G, 472W, 473G, 474H, 478V, 492A, 494K, 530V, 550F, 551E, 552V, 553L, 556N, 598D, 600K, 602E, 603N, 605L, 749D
CDD
cd14136 (STKc_SRPK)

494K

ATP binding site
470L, 471G, 472W, 473G, 474H, 478V, 492A, 494K, 530V, 550F, 551E, 552V, 553L, 556N, 598D, 600K, 602E, 603N, 605L, 749D
CDD
cd14136 (STKc_SRPK)

530V

ATP binding site
470L, 471G, 472W, 473G, 474H, 478V, 492A, 494K, 530V, 550F, 551E, 552V, 553L, 556N, 598D, 600K, 602E, 603N, 605L, 749D
CDD
cd14136 (STKc_SRPK)

550F

ATP binding site
470L, 471G, 472W, 473G, 474H, 478V, 492A, 494K, 530V, 550F, 551E, 552V, 553L, 556N, 598D, 600K, 602E, 603N, 605L, 749D
CDD
cd14136 (STKc_SRPK)

551E

ATP binding site
470L, 471G, 472W, 473G, 474H, 478V, 492A, 494K, 530V, 550F, 551E, 552V, 553L, 556N, 598D, 600K, 602E, 603N, 605L, 749D
CDD
cd14136 (STKc_SRPK)

552V

ATP binding site
470L, 471G, 472W, 473G, 474H, 478V, 492A, 494K, 530V, 550F, 551E, 552V, 553L, 556N, 598D, 600K, 602E, 603N, 605L, 749D
CDD
cd14136 (STKc_SRPK)

553L

ATP binding site
470L, 471G, 472W, 473G, 474H, 478V, 492A, 494K, 530V, 550F, 551E, 552V, 553L, 556N, 598D, 600K, 602E, 603N, 605L, 749D
CDD
cd14136 (STKc_SRPK)

556N

ATP binding site
470L, 471G, 472W, 473G, 474H, 478V, 492A, 494K, 530V, 550F, 551E, 552V, 553L, 556N, 598D, 600K, 602E, 603N, 605L, 749D
CDD
cd14136 (STKc_SRPK)

598D

ATP binding site
470L, 471G, 472W, 473G, 474H, 478V, 492A, 494K, 530V, 550F, 551E, 552V, 553L, 556N, 598D, 600K, 602E, 603N, 605L, 749D
CDD
cd14136 (STKc_SRPK)

600K

ATP binding site
470L, 471G, 472W, 473G, 474H, 478V, 492A, 494K, 530V, 550F, 551E, 552V, 553L, 556N, 598D, 600K, 602E, 603N, 605L, 749D
CDD
cd14136 (STKc_SRPK)

602E

ATP binding site
470L, 471G, 472W, 473G, 474H, 478V, 492A, 494K, 530V, 550F, 551E, 552V, 553L, 556N, 598D, 600K, 602E, 603N, 605L, 749D
CDD
cd14136 (STKc_SRPK)

603N

ATP binding site
470L, 471G, 472W, 473G, 474H, 478V, 492A, 494K, 530V, 550F, 551E, 552V, 553L, 556N, 598D, 600K, 602E, 603N, 605L, 749D
CDD
cd14136 (STKc_SRPK)

605L

ATP binding site
470L, 471G, 472W, 473G, 474H, 478V, 492A, 494K, 530V, 550F, 551E, 552V, 553L, 556N, 598D, 600K, 602E, 603N, 605L, 749D
CDD
cd14136 (STKc_SRPK)

749D

ATP binding site
470L, 471G, 472W, 473G, 474H, 478V, 492A, 494K, 530V, 550F, 551E, 552V, 553L, 556N, 598D, 600K, 602E, 603N, 605L, 749D
CDD
cd14136 (STKc_SRPK)
active site cd14136

470L

active site
470L, 471G, 472W, 473G, 474H, 478V, 492A, 494K, 508D, 530V, 550F, 551E, 552V, 553L, 556N, 558L, 559G, 598D, 600K, 602E, 603N, 605L, 749D, 752N, 761T, 763D, 764I, 765Q, 766T, 768Q, 805P
CDD
cd14136 (STKc_SRPK)

471G

active site
470L, 471G, 472W, 473G, 474H, 478V, 492A, 494K, 508D, 530V, 550F, 551E, 552V, 553L, 556N, 558L, 559G, 598D, 600K, 602E, 603N, 605L, 749D, 752N, 761T, 763D, 764I, 765Q, 766T, 768Q, 805P
CDD
cd14136 (STKc_SRPK)

472W

active site
470L, 471G, 472W, 473G, 474H, 478V, 492A, 494K, 508D, 530V, 550F, 551E, 552V, 553L, 556N, 558L, 559G, 598D, 600K, 602E, 603N, 605L, 749D, 752N, 761T, 763D, 764I, 765Q, 766T, 768Q, 805P
CDD
cd14136 (STKc_SRPK)

473G

active site
470L, 471G, 472W, 473G, 474H, 478V, 492A, 494K, 508D, 530V, 550F, 551E, 552V, 553L, 556N, 558L, 559G, 598D, 600K, 602E, 603N, 605L, 749D, 752N, 761T, 763D, 764I, 765Q, 766T, 768Q, 805P
CDD
cd14136 (STKc_SRPK)

474H

active site
470L, 471G, 472W, 473G, 474H, 478V, 492A, 494K, 508D, 530V, 550F, 551E, 552V, 553L, 556N, 558L, 559G, 598D, 600K, 602E, 603N, 605L, 749D, 752N, 761T, 763D, 764I, 765Q, 766T, 768Q, 805P
CDD
cd14136 (STKc_SRPK)

478V

active site
470L, 471G, 472W, 473G, 474H, 478V, 492A, 494K, 508D, 530V, 550F, 551E, 552V, 553L, 556N, 558L, 559G, 598D, 600K, 602E, 603N, 605L, 749D, 752N, 761T, 763D, 764I, 765Q, 766T, 768Q, 805P
CDD
cd14136 (STKc_SRPK)

492A

active site
470L, 471G, 472W, 473G, 474H, 478V, 492A, 494K, 508D, 530V, 550F, 551E, 552V, 553L, 556N, 558L, 559G, 598D, 600K, 602E, 603N, 605L, 749D, 752N, 761T, 763D, 764I, 765Q, 766T, 768Q, 805P
CDD
cd14136 (STKc_SRPK)

494K

active site
470L, 471G, 472W, 473G, 474H, 478V, 492A, 494K, 508D, 530V, 550F, 551E, 552V, 553L, 556N, 558L, 559G, 598D, 600K, 602E, 603N, 605L, 749D, 752N, 761T, 763D, 764I, 765Q, 766T, 768Q, 805P
CDD
cd14136 (STKc_SRPK)

508D

active site
470L, 471G, 472W, 473G, 474H, 478V, 492A, 494K, 508D, 530V, 550F, 551E, 552V, 553L, 556N, 558L, 559G, 598D, 600K, 602E, 603N, 605L, 749D, 752N, 761T, 763D, 764I, 765Q, 766T, 768Q, 805P
CDD
cd14136 (STKc_SRPK)

530V

active site
470L, 471G, 472W, 473G, 474H, 478V, 492A, 494K, 508D, 530V, 550F, 551E, 552V, 553L, 556N, 558L, 559G, 598D, 600K, 602E, 603N, 605L, 749D, 752N, 761T, 763D, 764I, 765Q, 766T, 768Q, 805P
CDD
cd14136 (STKc_SRPK)

550F

active site
470L, 471G, 472W, 473G, 474H, 478V, 492A, 494K, 508D, 530V, 550F, 551E, 552V, 553L, 556N, 558L, 559G, 598D, 600K, 602E, 603N, 605L, 749D, 752N, 761T, 763D, 764I, 765Q, 766T, 768Q, 805P
CDD
cd14136 (STKc_SRPK)

551E

active site
470L, 471G, 472W, 473G, 474H, 478V, 492A, 494K, 508D, 530V, 550F, 551E, 552V, 553L, 556N, 558L, 559G, 598D, 600K, 602E, 603N, 605L, 749D, 752N, 761T, 763D, 764I, 765Q, 766T, 768Q, 805P
CDD
cd14136 (STKc_SRPK)

552V

active site
470L, 471G, 472W, 473G, 474H, 478V, 492A, 494K, 508D, 530V, 550F, 551E, 552V, 553L, 556N, 558L, 559G, 598D, 600K, 602E, 603N, 605L, 749D, 752N, 761T, 763D, 764I, 765Q, 766T, 768Q, 805P
CDD
cd14136 (STKc_SRPK)

553L

active site
470L, 471G, 472W, 473G, 474H, 478V, 492A, 494K, 508D, 530V, 550F, 551E, 552V, 553L, 556N, 558L, 559G, 598D, 600K, 602E, 603N, 605L, 749D, 752N, 761T, 763D, 764I, 765Q, 766T, 768Q, 805P
CDD
cd14136 (STKc_SRPK)

556N

active site
470L, 471G, 472W, 473G, 474H, 478V, 492A, 494K, 508D, 530V, 550F, 551E, 552V, 553L, 556N, 558L, 559G, 598D, 600K, 602E, 603N, 605L, 749D, 752N, 761T, 763D, 764I, 765Q, 766T, 768Q, 805P
CDD
cd14136 (STKc_SRPK)

558L

active site
470L, 471G, 472W, 473G, 474H, 478V, 492A, 494K, 508D, 530V, 550F, 551E, 552V, 553L, 556N, 558L, 559G, 598D, 600K, 602E, 603N, 605L, 749D, 752N, 761T, 763D, 764I, 765Q, 766T, 768Q, 805P
CDD
cd14136 (STKc_SRPK)

559G

active site
470L, 471G, 472W, 473G, 474H, 478V, 492A, 494K, 508D, 530V, 550F, 551E, 552V, 553L, 556N, 558L, 559G, 598D, 600K, 602E, 603N, 605L, 749D, 752N, 761T, 763D, 764I, 765Q, 766T, 768Q, 805P
CDD
cd14136 (STKc_SRPK)

598D

active site
470L, 471G, 472W, 473G, 474H, 478V, 492A, 494K, 508D, 530V, 550F, 551E, 552V, 553L, 556N, 558L, 559G, 598D, 600K, 602E, 603N, 605L, 749D, 752N, 761T, 763D, 764I, 765Q, 766T, 768Q, 805P
CDD
cd14136 (STKc_SRPK)

600K

active site
470L, 471G, 472W, 473G, 474H, 478V, 492A, 494K, 508D, 530V, 550F, 551E, 552V, 553L, 556N, 558L, 559G, 598D, 600K, 602E, 603N, 605L, 749D, 752N, 761T, 763D, 764I, 765Q, 766T, 768Q, 805P
CDD
cd14136 (STKc_SRPK)

602E

active site
470L, 471G, 472W, 473G, 474H, 478V, 492A, 494K, 508D, 530V, 550F, 551E, 552V, 553L, 556N, 558L, 559G, 598D, 600K, 602E, 603N, 605L, 749D, 752N, 761T, 763D, 764I, 765Q, 766T, 768Q, 805P
CDD
cd14136 (STKc_SRPK)

603N

active site
470L, 471G, 472W, 473G, 474H, 478V, 492A, 494K, 508D, 530V, 550F, 551E, 552V, 553L, 556N, 558L, 559G, 598D, 600K, 602E, 603N, 605L, 749D, 752N, 761T, 763D, 764I, 765Q, 766T, 768Q, 805P
CDD
cd14136 (STKc_SRPK)

605L

active site
470L, 471G, 472W, 473G, 474H, 478V, 492A, 494K, 508D, 530V, 550F, 551E, 552V, 553L, 556N, 558L, 559G, 598D, 600K, 602E, 603N, 605L, 749D, 752N, 761T, 763D, 764I, 765Q, 766T, 768Q, 805P
CDD
cd14136 (STKc_SRPK)

749D

active site
470L, 471G, 472W, 473G, 474H, 478V, 492A, 494K, 508D, 530V, 550F, 551E, 552V, 553L, 556N, 558L, 559G, 598D, 600K, 602E, 603N, 605L, 749D, 752N, 761T, 763D, 764I, 765Q, 766T, 768Q, 805P
CDD
cd14136 (STKc_SRPK)

752N

active site
470L, 471G, 472W, 473G, 474H, 478V, 492A, 494K, 508D, 530V, 550F, 551E, 552V, 553L, 556N, 558L, 559G, 598D, 600K, 602E, 603N, 605L, 749D, 752N, 761T, 763D, 764I, 765Q, 766T, 768Q, 805P
CDD
cd14136 (STKc_SRPK)

761T

active site
470L, 471G, 472W, 473G, 474H, 478V, 492A, 494K, 508D, 530V, 550F, 551E, 552V, 553L, 556N, 558L, 559G, 598D, 600K, 602E, 603N, 605L, 749D, 752N, 761T, 763D, 764I, 765Q, 766T, 768Q, 805P
CDD
cd14136 (STKc_SRPK)

763D

active site
470L, 471G, 472W, 473G, 474H, 478V, 492A, 494K, 508D, 530V, 550F, 551E, 552V, 553L, 556N, 558L, 559G, 598D, 600K, 602E, 603N, 605L, 749D, 752N, 761T, 763D, 764I, 765Q, 766T, 768Q, 805P
CDD
cd14136 (STKc_SRPK)

764I

active site
470L, 471G, 472W, 473G, 474H, 478V, 492A, 494K, 508D, 530V, 550F, 551E, 552V, 553L, 556N, 558L, 559G, 598D, 600K, 602E, 603N, 605L, 749D, 752N, 761T, 763D, 764I, 765Q, 766T, 768Q, 805P
CDD
cd14136 (STKc_SRPK)

765Q

active site
470L, 471G, 472W, 473G, 474H, 478V, 492A, 494K, 508D, 530V, 550F, 551E, 552V, 553L, 556N, 558L, 559G, 598D, 600K, 602E, 603N, 605L, 749D, 752N, 761T, 763D, 764I, 765Q, 766T, 768Q, 805P
CDD
cd14136 (STKc_SRPK)

766T

active site
470L, 471G, 472W, 473G, 474H, 478V, 492A, 494K, 508D, 530V, 550F, 551E, 552V, 553L, 556N, 558L, 559G, 598D, 600K, 602E, 603N, 605L, 749D, 752N, 761T, 763D, 764I, 765Q, 766T, 768Q, 805P
CDD
cd14136 (STKc_SRPK)

768Q

active site
470L, 471G, 472W, 473G, 474H, 478V, 492A, 494K, 508D, 530V, 550F, 551E, 552V, 553L, 556N, 558L, 559G, 598D, 600K, 602E, 603N, 605L, 749D, 752N, 761T, 763D, 764I, 765Q, 766T, 768Q, 805P
CDD
cd14136 (STKc_SRPK)

805P

active site
470L, 471G, 472W, 473G, 474H, 478V, 492A, 494K, 508D, 530V, 550F, 551E, 552V, 553L, 556N, 558L, 559G, 598D, 600K, 602E, 603N, 605L, 749D, 752N, 761T, 763D, 764I, 765Q, 766T, 768Q, 805P
CDD
cd14136 (STKc_SRPK)
polypeptide substr...

508D

polypeptide substrate binding site
508D, 558L, 598D, 600K, 752N, 761T, 763D, 764I, 765Q, 766T, 768Q, 805P
CDD
cd14136 (STKc_SRPK)

558L

polypeptide substrate binding site
508D, 558L, 598D, 600K, 752N, 761T, 763D, 764I, 765Q, 766T, 768Q, 805P
CDD
cd14136 (STKc_SRPK)

598D

polypeptide substrate binding site
508D, 558L, 598D, 600K, 752N, 761T, 763D, 764I, 765Q, 766T, 768Q, 805P
CDD
cd14136 (STKc_SRPK)

600K

polypeptide substrate binding site
508D, 558L, 598D, 600K, 752N, 761T, 763D, 764I, 765Q, 766T, 768Q, 805P
CDD
cd14136 (STKc_SRPK)

752N

polypeptide substrate binding site
508D, 558L, 598D, 600K, 752N, 761T, 763D, 764I, 765Q, 766T, 768Q, 805P
CDD
cd14136 (STKc_SRPK)

761T

polypeptide substrate binding site
508D, 558L, 598D, 600K, 752N, 761T, 763D, 764I, 765Q, 766T, 768Q, 805P
CDD
cd14136 (STKc_SRPK)

763D

polypeptide substrate binding site
508D, 558L, 598D, 600K, 752N, 761T, 763D, 764I, 765Q, 766T, 768Q, 805P
CDD
cd14136 (STKc_SRPK)

764I

polypeptide substrate binding site
508D, 558L, 598D, 600K, 752N, 761T, 763D, 764I, 765Q, 766T, 768Q, 805P
CDD
cd14136 (STKc_SRPK)

765Q

polypeptide substrate binding site
508D, 558L, 598D, 600K, 752N, 761T, 763D, 764I, 765Q, 766T, 768Q, 805P
CDD
cd14136 (STKc_SRPK)

766T

polypeptide substrate binding site
508D, 558L, 598D, 600K, 752N, 761T, 763D, 764I, 765Q, 766T, 768Q, 805P
CDD
cd14136 (STKc_SRPK)

768Q

polypeptide substrate binding site
508D, 558L, 598D, 600K, 752N, 761T, 763D, 764I, 765Q, 766T, 768Q, 805P
CDD
cd14136 (STKc_SRPK)

805P

polypeptide substrate binding site
508D, 558L, 598D, 600K, 752N, 761T, 763D, 764I, 765Q, 766T, 768Q, 805P
CDD
cd14136 (STKc_SRPK)
kinase-docking sit...

566Y

kinase-docking site
566Y, 567K, 798T, 800N, 802L, 811Y, 816D, 819A, 820Q, 823E, 824L, 852I, 856R, 858K, 867Y
CDD
cd14136 (STKc_SRPK)

567K

kinase-docking site
566Y, 567K, 798T, 800N, 802L, 811Y, 816D, 819A, 820Q, 823E, 824L, 852I, 856R, 858K, 867Y
CDD
cd14136 (STKc_SRPK)

798T

kinase-docking site
566Y, 567K, 798T, 800N, 802L, 811Y, 816D, 819A, 820Q, 823E, 824L, 852I, 856R, 858K, 867Y
CDD
cd14136 (STKc_SRPK)

800N

kinase-docking site
566Y, 567K, 798T, 800N, 802L, 811Y, 816D, 819A, 820Q, 823E, 824L, 852I, 856R, 858K, 867Y
CDD
cd14136 (STKc_SRPK)

802L

kinase-docking site
566Y, 567K, 798T, 800N, 802L, 811Y, 816D, 819A, 820Q, 823E, 824L, 852I, 856R, 858K, 867Y
CDD
cd14136 (STKc_SRPK)

811Y

kinase-docking site
566Y, 567K, 798T, 800N, 802L, 811Y, 816D, 819A, 820Q, 823E, 824L, 852I, 856R, 858K, 867Y
CDD
cd14136 (STKc_SRPK)

816D

kinase-docking site
566Y, 567K, 798T, 800N, 802L, 811Y, 816D, 819A, 820Q, 823E, 824L, 852I, 856R, 858K, 867Y
CDD
cd14136 (STKc_SRPK)

819A

kinase-docking site
566Y, 567K, 798T, 800N, 802L, 811Y, 816D, 819A, 820Q, 823E, 824L, 852I, 856R, 858K, 867Y
CDD
cd14136 (STKc_SRPK)

820Q

kinase-docking site
566Y, 567K, 798T, 800N, 802L, 811Y, 816D, 819A, 820Q, 823E, 824L, 852I, 856R, 858K, 867Y
CDD
cd14136 (STKc_SRPK)

823E

kinase-docking site
566Y, 567K, 798T, 800N, 802L, 811Y, 816D, 819A, 820Q, 823E, 824L, 852I, 856R, 858K, 867Y
CDD
cd14136 (STKc_SRPK)

824L

kinase-docking site
566Y, 567K, 798T, 800N, 802L, 811Y, 816D, 819A, 820Q, 823E, 824L, 852I, 856R, 858K, 867Y
CDD
cd14136 (STKc_SRPK)

852I

kinase-docking site
566Y, 567K, 798T, 800N, 802L, 811Y, 816D, 819A, 820Q, 823E, 824L, 852I, 856R, 858K, 867Y
CDD
cd14136 (STKc_SRPK)

856R

kinase-docking site
566Y, 567K, 798T, 800N, 802L, 811Y, 816D, 819A, 820Q, 823E, 824L, 852I, 856R, 858K, 867Y
CDD
cd14136 (STKc_SRPK)

858K

kinase-docking site
566Y, 567K, 798T, 800N, 802L, 811Y, 816D, 819A, 820Q, 823E, 824L, 852I, 856R, 858K, 867Y
CDD
cd14136 (STKc_SRPK)

867Y

kinase-docking site
566Y, 567K, 798T, 800N, 802L, 811Y, 816D, 819A, 820Q, 823E, 824L, 852I, 856R, 858K, 867Y
CDD
cd14136 (STKc_SRPK)
activation loop (A...

748A

activation loop (A-loop)
748A, 749D, 750L, 751G, 752N, 753A, 754C, 755W, 756V, 757N, 758R, 759H, 760F, 761T, 762N, 763D, 764I, 765Q, 766T, 767R, 768Q
CDD
cd14136 (STKc_SRPK)

749D

activation loop (A-loop)
748A, 749D, 750L, 751G, 752N, 753A, 754C, 755W, 756V, 757N, 758R, 759H, 760F, 761T, 762N, 763D, 764I, 765Q, 766T, 767R, 768Q
CDD
cd14136 (STKc_SRPK)

750L

activation loop (A-loop)
748A, 749D, 750L, 751G, 752N, 753A, 754C, 755W, 756V, 757N, 758R, 759H, 760F, 761T, 762N, 763D, 764I, 765Q, 766T, 767R, 768Q
CDD
cd14136 (STKc_SRPK)

751G

activation loop (A-loop)
748A, 749D, 750L, 751G, 752N, 753A, 754C, 755W, 756V, 757N, 758R, 759H, 760F, 761T, 762N, 763D, 764I, 765Q, 766T, 767R, 768Q
CDD
cd14136 (STKc_SRPK)

752N

activation loop (A-loop)
748A, 749D, 750L, 751G, 752N, 753A, 754C, 755W, 756V, 757N, 758R, 759H, 760F, 761T, 762N, 763D, 764I, 765Q, 766T, 767R, 768Q
CDD
cd14136 (STKc_SRPK)

753A

activation loop (A-loop)
748A, 749D, 750L, 751G, 752N, 753A, 754C, 755W, 756V, 757N, 758R, 759H, 760F, 761T, 762N, 763D, 764I, 765Q, 766T, 767R, 768Q
CDD
cd14136 (STKc_SRPK)

754C

activation loop (A-loop)
748A, 749D, 750L, 751G, 752N, 753A, 754C, 755W, 756V, 757N, 758R, 759H, 760F, 761T, 762N, 763D, 764I, 765Q, 766T, 767R, 768Q
CDD
cd14136 (STKc_SRPK)

755W

activation loop (A-loop)
748A, 749D, 750L, 751G, 752N, 753A, 754C, 755W, 756V, 757N, 758R, 759H, 760F, 761T, 762N, 763D, 764I, 765Q, 766T, 767R, 768Q
CDD
cd14136 (STKc_SRPK)

756V

activation loop (A-loop)
748A, 749D, 750L, 751G, 752N, 753A, 754C, 755W, 756V, 757N, 758R, 759H, 760F, 761T, 762N, 763D, 764I, 765Q, 766T, 767R, 768Q
CDD
cd14136 (STKc_SRPK)

757N

activation loop (A-loop)
748A, 749D, 750L, 751G, 752N, 753A, 754C, 755W, 756V, 757N, 758R, 759H, 760F, 761T, 762N, 763D, 764I, 765Q, 766T, 767R, 768Q
CDD
cd14136 (STKc_SRPK)

758R

activation loop (A-loop)
748A, 749D, 750L, 751G, 752N, 753A, 754C, 755W, 756V, 757N, 758R, 759H, 760F, 761T, 762N, 763D, 764I, 765Q, 766T, 767R, 768Q
CDD
cd14136 (STKc_SRPK)

759H

activation loop (A-loop)
748A, 749D, 750L, 751G, 752N, 753A, 754C, 755W, 756V, 757N, 758R, 759H, 760F, 761T, 762N, 763D, 764I, 765Q, 766T, 767R, 768Q
CDD
cd14136 (STKc_SRPK)

760F

activation loop (A-loop)
748A, 749D, 750L, 751G, 752N, 753A, 754C, 755W, 756V, 757N, 758R, 759H, 760F, 761T, 762N, 763D, 764I, 765Q, 766T, 767R, 768Q
CDD
cd14136 (STKc_SRPK)

761T

activation loop (A-loop)
748A, 749D, 750L, 751G, 752N, 753A, 754C, 755W, 756V, 757N, 758R, 759H, 760F, 761T, 762N, 763D, 764I, 765Q, 766T, 767R, 768Q
CDD
cd14136 (STKc_SRPK)

762N

activation loop (A-loop)
748A, 749D, 750L, 751G, 752N, 753A, 754C, 755W, 756V, 757N, 758R, 759H, 760F, 761T, 762N, 763D, 764I, 765Q, 766T, 767R, 768Q
CDD
cd14136 (STKc_SRPK)

763D

activation loop (A-loop)
748A, 749D, 750L, 751G, 752N, 753A, 754C, 755W, 756V, 757N, 758R, 759H, 760F, 761T, 762N, 763D, 764I, 765Q, 766T, 767R, 768Q
CDD
cd14136 (STKc_SRPK)

764I

activation loop (A-loop)
748A, 749D, 750L, 751G, 752N, 753A, 754C, 755W, 756V, 757N, 758R, 759H, 760F, 761T, 762N, 763D, 764I, 765Q, 766T, 767R, 768Q
CDD
cd14136 (STKc_SRPK)

765Q

activation loop (A-loop)
748A, 749D, 750L, 751G, 752N, 753A, 754C, 755W, 756V, 757N, 758R, 759H, 760F, 761T, 762N, 763D, 764I, 765Q, 766T, 767R, 768Q
CDD
cd14136 (STKc_SRPK)

766T

activation loop (A-loop)
748A, 749D, 750L, 751G, 752N, 753A, 754C, 755W, 756V, 757N, 758R, 759H, 760F, 761T, 762N, 763D, 764I, 765Q, 766T, 767R, 768Q
CDD
cd14136 (STKc_SRPK)

767R

activation loop (A-loop)
748A, 749D, 750L, 751G, 752N, 753A, 754C, 755W, 756V, 757N, 758R, 759H, 760F, 761T, 762N, 763D, 764I, 765Q, 766T, 767R, 768Q
CDD
cd14136 (STKc_SRPK)

768Q

activation loop (A-loop)
748A, 749D, 750L, 751G, 752N, 753A, 754C, 755W, 756V, 757N, 758R, 759H, 760F, 761T, 762N, 763D, 764I, 765Q, 766T, 767R, 768Q
CDD
cd14136 (STKc_SRPK)

Protein sequence

>MIA_03914_1
MAATVDSPSAASAAAAAAAAAASSTSTSGNPNSTPSTSNKHHHYHKSHGHHGHHGHHGHHLSHHTNSSNQSTSHSSHPHH
HSKKDSHHLKAKQSPQLPPASDASSPSLESGSSSPESHKPSFSSPPASSSPSFSLASPSASALASSPTSAPSPTAASMPS
NSTSSAGPPPFFKTDILSSAAAAAAAAAAVAVAAVTNSSTSAKNNTTNASSTTTNTSVTSTAGLSVSGSPEKHLAPMANI
PAAQSFSTSNATPASAAAAAASATFSNQQQSLAAHPIINNASTHSIDQDLGVDLSPTNTNSLHLNAATPQPASPTLSINT
LQAPTQPSDDLPPKYSEISPRSSTFSSTATPSNAAAAAAAAAAAAAAATGTSISPNSSISSASTSIAPTKSSSAVSTSSK
KLPDTPMDTSATNTSDNSSYSDSCSEDDDDDDEMSPNDEENAQDYCTGGYHPVEIGETFKEGRYVIVRKLGWGHFSTVWL
AKDTHNNNRHVAMKVVRSAVHYTEAAIDEIHLLKRAVEANPDHPGRKHVVSLLDSFQHEGPNGSHVCMVFEVLGENLLGL
IKRYKYKGIPMPLVKQITKQVLLALDYLHRECGIIHTDLKPENVLIEIGDVEFIVKQLEEEEQLKRMQSRAKRRASEASS
ADPSALRKGRRPRRKSVVTGSQPLPSPLRSNSVFFNEFSMSPAFISDADSSVPNSAPTSKATSKTRVSLANSVASSVAPS
RSSSQAALYGSQYGQTALEEGLISVKIADLGNACWVNRHFTNDIQTRQYRSPEVLLGSFWGASTDVWSMACLVFELLTGN
YLFDPHSAQTYSKDDDHIAQIIELLGRMSSHVLLTGKWASEYFNRRGELRHIKKLRPKPLYEVLKEYNFSNEDCEAIASF
LLPMLELNPKKRADAGGMSNHEWLKDAMGFENVIPIDRVAGASGKDIEGWCKEVRRR

GO term prediction

Biological Process

GO:0006468 protein phosphorylation

Molecular Function

GO:0004672 protein kinase activity
GO:0005524 ATP binding

Cellular Component