Protein

MCA_03425_1

Length
855 amino acids

Gene name: SKY1

Description: Serine/threonine protein kinase Sky1; in S. cerevisiae involved in regulating proteins involved in mRNA metabolism and cation homeostasis

Browser: contigB:4396446-4399014-

RNA-seq: read pairs 3950, FPKM 57.0, percentile rank 68.2% (100% = highest expression)

Protein function

Annotation:SKY1Serine/threonine protein kinase Sky1; in S. cerevisiae involved in regulating proteins involved in mRNA metabolism and cation homeostasis
KEGG:K08832SRPK3 serine/threonine-protein kinase SRPK3 [EC:2.7.11.1]
EGGNOG:0PFP2DSK1protein kinase dsk1
SGD closest match:S000004829SKY1Serine/threonine-protein kinase SKY1
CGD closest match:CAL0000186077orf19.2436Serine/threonine protein kinase

Protein alignments

%idAln lengthE-value
MIA_03914_182.33%2664e-142MIA_03914_1
A0A0J9XJX6_GEOCN73.44%2566e-110Similar to Saccharomyces cerevisiae YMR216C SKY1 SR protein kinase (SRPK) involved in regulating proteins involved in mRNA metabolism and cation homeostasis OS=Geotrichum candidum GN=BN980_GECA26s00659g PE=4 SV=1
A0A060SZX7_BLAAD69.83%2421e-109ARAD1C12122p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C12122g PE=4 SV=1
A0A1E3PGG9_9ASCO66.93%2543e-107Kinase-like protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_52641 PE=4 SV=1
UniRef50_A0A1E3PGG966.93%2547e-104Kinase-like protein n=1 Tax=Nadsonia fulvescens var. elongata DSM 6958 TaxID=857566 RepID=A0A1E3PGG9_9ASCO
A0A161HKF5_9ASCO67.24%2321e-101Serine/threonine protein kinase SKY1 OS=Sugiyamaella lignohabitans GN=SKY1 PE=4 SV=1
Q6CGK3_YARLI65.97%2381e-101YALI0A18590p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_A18590g PE=3 SV=2
A0A1E4TK38_9ASCO62.88%2647e-97Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_22954 PE=4 SV=1
SKY1_YEAST53.96%2652e-81Serine/threonine-protein kinase SKY1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SKY1 PE=1 SV=1
A0A1D8PDS9_CANAL66.32%1933e-80Serine/threonine protein kinase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.2436 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.1538

Protein family membership

None predicted.

Domains and repeats

  1. Domain
1 100 200 300 400 500 600 700 800 855

Detailed signature matches

  1. Domain IPR011009
    Protein kinase-like domain
    1. SSF56112 (Protein k...)
  2. Domain IPR000719
    Protein kinase domain
    1. PS50011 (PROTEIN_KI...)
    2. SM00220 (serkin_6)
    3. PF00069 (Pkinase)
  3. SITE IPR017441
    Protein kinase, ATP binding site
    1. PS00107 (PROTEIN_KI...)
  4. SITE IPR008271
    Serine/threonine-protein kinase, active site
    1. PS00108 (PROTEIN_KI...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. Coil
  2. G3DSA:1.10.51...
  3. G3DSA:3.30.20...
  4. mobidb-lite (disord...)

Protein sequence

>MCA_03425_1
MTALKISQDSSSTALADGASFETTKDHKNHSHNHHHHHHHHHHHHHHSKKDSHHLQKSLKESTSNPALEAVDENATAGNI
SSEQAKPDDTGKKVTSPTTVNDTKQANKSSESLNNKSTASEPEVPPSPPPHLSSYTSPKQTAPSSLGDMIQKNLNDSLKN
GKKELSLNTKGLSRTSTNTAILKEANNLETISSMLLQRAKLSTSNESLLPSLDTLTNSKSELKKPQKDAKNPSNASTRSN
SSDKEFHDEGDSDFSTESEESFHDEENANDYCSGGYHPVEIGETFKNGQYIIVRKLGWGHFSTVWLAKDTVNNNRHVAMK
IVRSAMHYTEAAIDEIHLLKRAVEANPNHPGRAHVVSLLDSFTHEGPNGSHVCMVFEVLGENLLSLMKRYKYKGIPLPLV
KQITKQVLYALDYLHRECGIIHTDIKPENVLIEIGDVESIVKQLEEEEEQKRQTKAKRRASDGGELAGRNCRRPRRKSVV
TGSQPLPSPLRSNSFLFPEFAMSPAIASDAESMPPTAANSKAPSKTRDFNNLIQHAHQFQQQQQLEHHLKLHENEQRKKE
EFSKEAESGPISPSFQKQIEGRLSSISISKNVSSTSLNNASSAALQSVTGVSSNTSMSEKSSEIQSSNDKIDSPESKSVS
RSVSPESNNASSRTALDENMISVKIADLGNACWVNRHFTNDIQTRQYRSPEVLLGAAWGASTDIWSMACLIFELITGNYL
FDPRSSDTYSKDDDHIAQIMELLGRMSSHLLLSGKWASEYFNRRGELRNVKKLKPYSLYDVLRDYKFSKDDAEMISSFLL
PMLDMNPKRRADAGGMTNHEWLKDVNIFDPAQKIPRPAGGSGKDIPGWAKEIRRR

GO term prediction

Biological Process

GO:0006468 protein phosphorylation

Molecular Function

GO:0004672 protein kinase activity
GO:0005524 ATP binding

Cellular Component

None predicted.