Protein

MIA_03854_1

Length
432 amino acids

Browser: contig05:57986-59375+

Protein function

EGGNOG:0PFNQPGUG_04212RNA Methylase
SGD closest match:S000005484TRM11tRNA (guanine(10)-N2)-methyltransferase
CGD closest match:CAL0000185296orf19.5987tRNA (Guanine-N2-)-methyltransferase

Protein alignments

%idAln lengthE-value
MCA_02267_174.77%4320.0MCA_02267_1
A0A0J9X4I5_GEOCN66.20%4320.0Similar to Saccharomyces cerevisiae YOL124C TRM11 Catalytic subunit of an adoMet-dependent tRNA methyltransferase complex (Trm11p-Trm112p) OS=Geotrichum candidum GN=BN980_GECA02s04971g PE=4 SV=1
A0A167FHC9_9ASCO58.68%4380.0Trm11p OS=Sugiyamaella lignohabitans GN=TRM11 PE=4 SV=1
A0A1E3PPQ2_9ASCO55.89%4330.0Putative ribonuclease methylating protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_22259 PE=4 SV=1
A0A060T4X0_BLAAD57.14%4349e-180ARAD1C06424p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C06424g PE=4 SV=1
Q6CC03_YARLI54.71%4356e-174YALI0C13882p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_C13882g PE=4 SV=1
UniRef50_Q6CC0354.71%4351e-170YALI0C13882p n=5 Tax=Saccharomycetales TaxID=4892 RepID=Q6CC03_YARLI
Q5ANB6_CANAL50.81%4335e-149tRNA (Guanine-N2-)-methyltransferase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.5987 PE=4 SV=1
TRM11_YEAST50.69%4346e-147tRNA (guanine(10)-N2)-methyltransferase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=TRM11 PE=1 SV=1
A0A1E4TJ19_9ASCO49.54%4326e-147Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_322 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.2188

Protein family membership

Domains and repeats

  1. Domain
  2. Domain
1 50 100 150 200 250 300 350 400 432

Detailed signature matches

  1. Family IPR016691
    tRNA guanosine-2'-O-methyltransferase, TRM11
    1. PS51627 (SAM_MT_TRM11)
  2. Domain IPR029063
    S-adenosyl-L-methionine-dependent methyltransferase
    1. SSF53335 (S-adenosy...)
  3. Domain IPR000241
    Putative RNA methylase domain
    1. PF01170 (UPF0020)
  4. SITE IPR002052
    DNA methylase, N-6 adenine-specific, conserved site
    1. PS00092 (N6_MTASE)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:3.40.50...
  2. NON_CYTOPLASM... (N...)
  3. PIRSF017259 (tRNA_M...)
  4. PR00507 (N12N6MTFRASE)
  5. SIGNAL_PEPTIDE (Sig...)
  6. SIGNAL_PEPTID... (S...)
  7. SIGNAL_PEPTID... (S...)
  8. SIGNAL_PEPTID... (S...)
  9. cd02440 (AdoMet_MTases)

Residue annotation

  1. S-adenosylmethioni...

Protein sequence

>MIA_03854_1
MKFLILLAQAHLDFRLTELKALSDFYKIDVDFSSYSTTSPFLVVDLDSPEDAYRLVHRSILCRSVYELYASGTSIEELHK
KTIENTSQWEKYKDEKISFKFEFVSYKGSRDQQEQVKIIESFSFMDLEGPIRMKRPDETFSIIEEYTVIGNKPEKLPKRV
WFGRFITNSNRSAMDHLDLKRRKYIGTTTFDAELSLVTCNIAQIAPGNIIYDPFCGTGSFLVAGGYMGALTCGSDIDVRM
LRGNAKDRTIDANFKQYGIQNKYLDVLTMDFTHNAFRKNFFFDAIVCDPPYGVREGLKVLGAKDEEKFSGKETVMIEGVA
AHLRKDYVPTKKPYELNALLDDLLEFAAVHLKPEGRLCYWMPVANEDFEENQIPLHEDLKFLSSCIQDFNKXTGSRRLLT
YSRRPYGEKGESQYVKGTLDEEFRTKYFRGFA

GO term prediction

Biological Process

GO:0032259 methylation

Molecular Function

GO:0003676 nucleic acid binding
GO:0008168 methyltransferase activity

Cellular Component

None predicted.