Protein

MIA_03837_1

Length
810 amino acids

Browser: contig05:22488-24921-

Protein function

EGGNOG:0PGAJGAP1GTPase-activating protein
SGD closest match:S000005441IRA2Inhibitory regulator protein IRA2
CGD closest match:CAL0000175167IQG1Ras GTPase-activating-like protein IQG1

Protein alignments

%idAln lengthE-value
MCA_02146_183.52%7830.0MCA_02146_1
A0A0J9X601_GEOCN68.49%7680.0Uncharacterized protein OS=Geotrichum candidum GN=BN980_GECA03s03981g PE=4 SV=1
A0A060T599_BLAAD67.91%7790.0ARAD1B05698p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1B05698g PE=4 SV=1
A0A167D7A0_9ASCO67.01%7790.0Ira1p OS=Sugiyamaella lignohabitans GN=IRA1 PE=4 SV=1
UniRef50_W0TYM259.85%7920.0YALI0E09086p n=3 Tax=Dipodascaceae TaxID=34353 RepID=W0TYM2_YARLI
W0TYM2_YARLI59.85%7920.0YALI0E09086p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E09086g PE=4 SV=1
A0A1E3PEI1_9ASCO49.59%4903e-142Rho GTPase activation protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_83928 PE=4 SV=1
A0A1E4TMB3_9ASCO40.66%6101e-143Uncharacterized protein (Fragment) OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_15563 PE=4 SV=1
IQG1_CANAL21.71%4331e-16Ras GTPase-activating-like protein IQG1 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=IQG1 PE=1 SV=2
IRA2_YEAST25.97%3087e-16Inhibitory regulator protein IRA2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=IRA2 PE=1 SV=2

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.4218
Predicted cleavage: 52

Protein family membership

None predicted.

Domains and repeats

  1. Domain
1 100 200 300 400 500 600 700 810

Detailed signature matches

  1. Domain IPR008936
    Rho GTPase activation protein
    1. SSF48350 (GTPase ac...)
  2. Domain IPR001936
    Ras GTPase-activating protein
    1. PS50018 (RAS_GTPASE...)
    2. PF00616 (RasGAP)
    3. SM00323 (RasGAP_2)
  3. Domain IPR000593
    RasGAP protein, C-terminal
    1. PF03836 (RasGAP_C)
  4. SITE IPR023152
    Ras GTPase-activating protein, conserved site
    1. PS00509 (RAS_GTPASE...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. Coil
  2. G3DSA:1.10.50...
  3. SSF143885 (RGC doma...)
  4. cd05132 (RasGAP_GAPA)
  5. mobidb-lite (disord...)

Residue annotation

  1. putative RAS inter...

Protein sequence

>MIA_03837_1
MSEQQLALTNSATRRQPSGTATVATTASNTTGGVPMSSVTSSNPNRQSKRYSVAALYMSMGGVDRDDDIDDELAKAQKFL
RELKSSISEQSKKNFLLEKDVRYLDSRIALLIQNRMGVEEQNEVASRLEPESSPENNINNEMSKDSDEYFPDRKKTELYG
NLFFLLQSEPKNIAVLCRLVSMAEIDSLLQTVMFTIYGNQYEQREEHLLLSMFQAVLAHQFENASEFSSLLRANTPVSRM
MTTYTRRPPGQAYLRSCLSDNLNRIIDQKDLNLEINPLKVYDELMDNNEDPFTSRPHITPDDAFRNPQVQALIKPRLIEL
DNIANDLLNTLISSLESVPYGIRWICKQIRLLTRRKYPTASETAVCSLIGAFFFLRFVNPAIVTPQAYMLVDKFPSDNSR
RILTLIAKMLQNLANKPSYSKEPYMSNLADFVSSNRSRINKFLNDLCEVPDFYESLEMDQYVALSKKDLKLPITLNEIFG
MHSLLEKYRSGLVQNEPSHLAILLDDLQKAPPLVPRAINGTMELHLYNRWETEVGDIDNNLDFLRADVIFMEAKTLMINI
IRSFPTGHVILQKPFDLHRIADFAAMNNEPGIVKRGIKALDLLNEIEESNPDDYDLLVSEVEYELNQLGSLKESVEKEAE
SLKAVYTIIREHNDYLRSQLNTYRSYLANVRQYTVGSKTDRPVGVSIIKDDNTINMTKKSGKVKSKTTKHRIIQKKFGIQ
NLQRDGVVSDWRLPQSRMGNLFLEIVSPTPGTFVLSLIMKGRPQPIFILDFKLDDLLEMKDKGVEFLDLKCLGINVKNLQ
ILLTEFSKKR

GO term prediction

Biological Process

GO:0007165 signal transduction
GO:0043087 regulation of GTPase activity

Molecular Function

GO:0005515 protein binding

Cellular Component

None predicted.