Protein

MIA_03798_1

Length
639 amino acids

Browser: contig04:2186919-2188940-

Protein function

EGGNOG:0PFVAUBA2Ubiquitin-activating enzyme
SGD closest match:S000002798UBA2Ubiquitin-activating enzyme E1-like
CGD closest match:CAL0000174476UBA2E1 ubiquitin-activating protein

Protein alignments

%idAln lengthE-value
MCA_03571_159.438%6410.0MCA_03571_1
A0A0J9XK53_GEOCN56.260%6150.0Similar to Saccharomyces cerevisiae YDR390C UBA2 Subunit of a heterodimeric nuclear SUMO activating enzyme (E1) with Aos1p OS=Geotrichum candidum GN=BN980_GECA24s00384g PE=4 SV=1
A0A060T2V8_BLAAD50.510%5887.98e-168ARAD1A03784p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1A03784g PE=4 SV=1
UniRef50_A0A060T2V850.510%5881.97e-164ARAD1A03784p n=1 Tax=Blastobotrys adeninivorans TaxID=409370 RepID=A0A060T2V8_BLAAD
A0A1E3PSK9_9ASCO51.718%5536.97e-162Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_68648 PE=4 SV=1
A0A1E4TC97_9ASCO47.744%5325.42e-151Uncharacterized protein (Fragment) OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_20431 PE=4 SV=1
Q6CA35_YARLI49.533%5352.05e-146YALI0D06259p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_D06259g PE=4 SV=1
A0A1D8PE77_CANAL43.660%6232.03e-138E1 ubiquitin-activating protein OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=UBA2 PE=4 SV=1
A0A167C8D8_9ASCO45.543%5161.86e-132E1 ubiquitin-activating protein UBA2 OS=Sugiyamaella lignohabitans GN=UBA2 PE=4 SV=1
UBA2_YEAST42.942%5031.67e-122Ubiquitin-activating enzyme E1-like OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=UBA2 PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0433

Protein family membership

Domains and repeats

  1. Domain
  2. Domain
1 100 200 300 400 500 639

Detailed signature matches

  1. Family IPR030661
    SUMO-activating enzyme subunit Uba2
    1. PIRSF039133 (SUMO_E1B)
  2. Domain IPR000594
    THIF-type NAD/FAD binding fold
    1. PF00899 (ThiF)
    2. SSF69572 (Activatin...)
  3. Domain IPR019572
    Ubiquitin-activating enzyme, catalytic cysteine domain
    1. PF10585 (UBA_e1_thi...)
  4. Domain IPR028077
    Ubiquitin/SUMO-activating enzyme ubiquitin-like domain
    1. PF14732 (UAE_UbL)
Unintegrated signatures no IPR
Unintegrated signatures
  1. Coil
  2. G3DSA:3.10.29...
  3. G3DSA:3.40.50...
  4. PS51257 (PROKAR_LIP...)
  5. mobidb-lite (disord...)

Protein sequence

>MIA_03798_1
MPDRSDYAIQTLGNDTYSKLKKARVLMVGAGGIGCELLKNLVLLGLGEIHVVDLDTVDLSNLNRQFLFSREHIKQPKAVV
AAQTASKFNPSVKIIPHFSDIKNTTLFPLDWFRSFDVVYNALDNKDARTYVNRMCLVTNTPLIESGTAGYLGQTQVIING
KTECYDCRPKPTPKSFAVCTIRSTPSQPVHTVVWAKNFLYAQLFDVSDEDHSVIDETTNEENAEEVKNLNKEANELKELH
SGLLEEDFAKKVFEKVFTTDIERLVSIDSMWKMRKPPTPFFYDKLVEEITKEENGVKSLAEKALKADQKDWTIAEAFAVY
KDATDRLQKRIKDSDGKPISFDKDDEDTLDFVVAAAQLRSYIFHIQTKSKFAFKQIAGNIIPAIATTNAVVAGLSVLQSI
KIISALDFSDRSHTSLDVITEKVLNGVSTVFLSAEPTAVFSLERTAKPEPKCVACGVSRAIISLDIKKTLLRDIVETLLD
KNWGYSPEVSVVTSDLIYDPDFDDNLDRTLDDLGIKPSGSITIMDEADEHDGEEGSRANVELYFLQADDVNSQEILKSFP
KITFHKKIVEMDEKEKTPDEPVAGMKRKLEDDDDESGNVAKKLKSVSQNDDGVIEIDLSDDENDGIIEIEDDDVVVLDD

GO term prediction

Biological Process

GO:0016925 protein sumoylation

Molecular Function

GO:0008641 small protein activating enzyme activity
GO:0019948 SUMO activating enzyme activity

Cellular Component

None predicted.