Protein

MIA_03786_1

Length
645 amino acids

Browser: contig04:2158497-2160435-

Protein function

EGGNOG:0QE5SPPN1Catalyzes the hydrolysis of inorganic polyphosphate (poly P) chains of many hundreds of phosphate residues into shorter lengths (By similarity)
SGD closest match:S000002860PPN1Endopolyphosphatase
CGD closest match:CAL0000182615PHM5Endopolyphosphatase

Protein alignments

%idAln lengthE-value
MCA_03614_154.337%6110.0MCA_03614_1
A0A0J9XDX0_GEOCN43.710%6206.09e-171Endopolyphosphatase OS=Geotrichum candidum GN=BN980_GECA11s01627g PE=4 SV=1
UniRef50_A0A0J9XDX043.710%6201.25e-167Endopolyphosphatase n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XDX0_GEOCN
A0A1E3PGY2_9ASCO37.959%6278.17e-126Endopolyphosphatase (Fragment) OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_7405 PE=4 SV=1
PPN1_YEAST37.361%6291.07e-123Endopolyphosphatase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PPN1 PE=1 SV=1
A0A1E4THM2_9ASCO37.221%5839.42e-124Uncharacterized protein (Fragment) OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_11772 PE=4 SV=1
A0A1D8PQR0_CANAL36.782%6091.88e-112Endopolyphosphatase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=PHM5 PE=4 SV=1
PPN1_YARLI38.205%4792.48e-99Endopolyphosphatase OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=PPN1 PE=3 SV=1
A0A167CXY4_9ASCO24.679%3121.78e-10Sphingomyelin phosphodiesterase OS=Sugiyamaella lignohabitans GN=PPN1 PE=3 SV=1
A0A060TAX3_BLAAD23.346%2572.05e-07ARAD1B10890p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1B10890g PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.4744
Predicted cleavage: 31

Protein family membership

Domains and repeats

  1. Domain
1 100 200 300 400 500 645

Detailed signature matches

  1. Family IPR012358
    Endopolyphosphatase, Ppn1p-related
    1. PIRSF027093 (Endopo...)
  2. Domain IPR029052
    Metallo-dependent phosphatase-like
    1. SSF56300 (Metallo-d...)
    2. G3DSA:3.60.21.10
Unintegrated signatures no IPR
Unintegrated signatures
  1. NON_CYTOPLASM... (N...)
  2. SIGNAL_PEPTIDE (Sig...)
  3. SIGNAL_PEPTID... (S...)
  4. SIGNAL_PEPTID... (S...)
  5. SIGNAL_PEPTID... (S...)
  6. SignalP-noTM

Protein sequence

>MIA_03786_1
MTRLLSPLLLLSLVAALPAQALNVPSGFRRTSEHDNNNHILLQQQDLQDNKNPHKNGIYVPDRPIFGRFLVITDIHPDPL
YEAHADPDTCCHRGSNGKEHPLSTGKYGLPISPCDSPIHLVNDTLHWIKENLHDSIDFIVWMGDNVRHDRDRHNPRSEPE
IFAANENVVNLFKNAFGTDDPYLPYEIPIIPNIGNNDVYPHNLVVEGPTLQSREFYRIYYEMVPPSQVHTFNRGMYFMTE
VIAGKLAVISINTLYWFETNPIVDGCDRKKDPGALQFRWLAITLKELRARGMKAWLSGHVPPTSSWESTCLYRYTAWLHE
YRDVIIGGLYGHMNIDHFIFHDVRDAYREKRKEGVAITHHDIPIDPNPRTKKEKLSARQKKLVRQFSRERDPKMTINGKQ
EYFNNLRLLYEDIYLGHEVDTNIGVSHIHTSIIPTYFPGFRIYEYDIDGLEDATPRSTYANGQPFKPWNEIFDATEAYLQ
HVKHLSYEDLDELDTKAEAEASSAFDLLHLAEEQDRLSAMKKKKGKKGKKGKKGGKKVVDPTWPPEYLEVEPGPAYKRQL
FTPLSYTQFFLNMTRINIQGENFSYDVEYETNKAPYNMSSLMAKDWIKLAGDLTTTEFASTSNSYELWKLYLHYAFASSS
FEVDL

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0000298 endopolyphosphatase activity

Cellular Component

GO:0005773 vacuole
GO:0016021 integral component of membrane