Protein

MCA_03614_1

Length
650 amino acids

Gene name: PPN1

Description: Endopolyphosphatase

Browser: contigC:546981-548934-

RNA-seq: read pairs 1348, FPKM 25.6, percentile rank 48.2% (100% = highest expression)

Protein function

Annotation:PPN1Endopolyphosphatase
KEGG:K06018PPN1 endopolyphosphatase [EC:3.6.1.10]
EGGNOG:0QE5SPPN1Catalyzes the hydrolysis of inorganic polyphosphate (poly P) chains of many hundreds of phosphate residues into shorter lengths (By similarity)
SGD closest match:S000002860PPN1Endopolyphosphatase
CGD closest match:CAL0000182615PHM5Endopolyphosphatase

Protein alignments

%idAln lengthE-value
MIA_03786_153.68%6110.0MIA_03786_1
A0A0J9XDX0_GEOCN47.59%5802e-180Endopolyphosphatase OS=Geotrichum candidum GN=BN980_GECA11s01627g PE=4 SV=1
UniRef50_A0A0J9XDX047.59%5805e-177Endopolyphosphatase n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XDX0_GEOCN
PPN1_YEAST38.06%6491e-138Endopolyphosphatase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PPN1 PE=1 SV=1
A0A1E3PGY2_9ASCO36.04%6271e-123Endopolyphosphatase (Fragment) OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_7405 PE=4 SV=1
A0A1D8PQR0_CANAL37.73%5913e-120Endopolyphosphatase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=PHM5 PE=4 SV=1
A0A1E4THM2_9ASCO36.07%6106e-120Uncharacterized protein (Fragment) OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_11772 PE=4 SV=1
PPN1_YARLI35.92%5291e-101Endopolyphosphatase OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=PPN1 PE=3 SV=1
A0A167CXY4_9ASCO23.96%3139e-12Sphingomyelin phosphodiesterase OS=Sugiyamaella lignohabitans GN=PPN1 PE=3 SV=1
A0A060TAX3_BLAAD24.73%2834e-09ARAD1B10890p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1B10890g PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.1168

Protein family membership

Domains and repeats

  1. Domain
1 100 200 300 400 500 600 650

Detailed signature matches

  1. Family IPR012358
    Endopolyphosphatase, Ppn1p-related
    1. PIRSF027093 (Endopo...)
  2. Domain IPR029052
    Metallo-dependent phosphatase-like
    1. SSF56300 (Metallo-d...)
    2. G3DSA:3.60.21.10
Unintegrated signatures no IPR
Unintegrated signatures
  1. NON_CYTOPLASM... (N...)
  2. SIGNAL_PEPTIDE (Sig...)
  3. SIGNAL_PEPTID... (S...)
  4. SIGNAL_PEPTID... (S...)
  5. SIGNAL_PEPTID... (S...)
  6. SignalP-noTM
  7. TMhelix
  8. mobidb-lite (disord...)

Protein sequence

>MCA_03614_1
MIRGAQSLVPGVLILTLLFFSALVASTSDKAAAAVIPKEGIEKKQQRAIQGRFLEITDIHPDPKYKPFTSTESCCHYGDG
KDEGEEGSTWKYGLPNSRCDTPLILVNDTLTWIKENIHGTIDFVVWTGDNVRHDRDRRTPRTEPEIFDANELMVNTLKDF
FGTGDIYHPYEIPIIPNIGNNDVYPHNMLVEGPTLQTREFYRIYRDLVPEAQVHIFNRGMHFVTEVIPDKLAVISINTIY
WFDTNPAVDGCDRKKDPGSLQFRWLRVVLNELRSRGMKAWVAGHVPPSQENWEPSCRDRFIAWSHEYRDVVLGGLWGHMN
LDHFLFHDVKEAYKLKKKEGVANEIGRLDIAEGEEVEEDDGQLPFNRNKKYKKLSPLQRQKMFNLFENDDNDEFTIQNKL
EYLNEVRLSYEKAYQDRNDDERFSMSYIHASIIPTYYPGFRIYEYNITGLDEAPSARVYEDGTPFRPWSEVFDDLNDYLT
EIDNMSLEELDELDEETDGMLSTRDIVEIAKKKKKGKKKGKKGGKKKKPKKLDPTWPPIFENVTRGPAYDPQLFTPVKFY
QYFLNMSYVNTKGNEFKYDIEYETDKAPYNMKSLVVSEWIKLAGRMTSYDNNDPTEEGEDQSPIDANKKLNIWEQFVQWA
FASSGFEKTL

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0000298 endopolyphosphatase activity

Cellular Component

GO:0005773 vacuole
GO:0016021 integral component of membrane