Protein
MIA_03760_1
Length
805 amino acids
Browser: contig04:2070905-2073464+
Protein function
| EGGNOG: | 0PGKD | SIR2 | histone deacetylase |
|---|---|---|---|
| SGD closest match: | S000005429 | HST1 | NAD-dependent protein deacetylase HST1 |
| CGD closest match: | CAL0000190389 | HST1 | NAD-dependent protein deacetylase HST1 |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| A0A0J9X9A4_GEOCN | 72.285% | 267 | 4.58e-134 | Similar to Saccharomyces cerevisiae YDL042C SIR2 Conserved NAD+ dependent histone deacetylase of the Sirtuin family involved in regulation of lifespan OS=Geotrichum candidum GN=BN980_GECA05s06775g PE=4 SV=1 |
| UniRef50_A0A0J9X9A4 | 72.285% | 267 | 9.37e-131 | Similar to Saccharomyces cerevisiae YDL042C SIR2 Conserved NAD+ dependent histone deacetylase of the Sirtuin family involved in regulation of lifespan n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9X9A4_GEOCN |
| MCA_04726_1 | 67.647% | 272 | 5.10e-125 | MCA_04726_1 |
| A0A167D863_9ASCO | 51.145% | 393 | 1.06e-122 | Histone deacetylase HST1 OS=Sugiyamaella lignohabitans GN=HST1 PE=4 SV=1 |
| A0A1E4TGZ2_9ASCO | 40.732% | 437 | 1.93e-100 | Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_148141 PE=4 SV=1 |
| HST1_YEAST | 45.330% | 364 | 9.32e-96 | NAD-dependent protein deacetylase HST1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=HST1 PE=1 SV=1 |
| A0A060SZ10_BLAAD | 46.099% | 282 | 4.12e-76 | ARAD1A16082p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1A16082g PE=4 SV=1 |
| HST1_CANAL | 48.133% | 241 | 1.30e-64 | NAD-dependent protein deacetylase HST1 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=HST1 PE=3 SV=2 |
| A0A1E3PEE8_9ASCO | 57.229% | 166 | 3.44e-63 | SIR2-domain-containing protein (Fragment) OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_5130 PE=4 SV=1 |
| Q6C219_YARLI | 58.599% | 157 | 9.15e-52 | YALI0F11583p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F11583g PE=4 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.0269
Protein family membership
- Sirtuin family (IPR003000)
Domains and repeats
-
Domain
1
100
200
300
400
500
600
700
805
Detailed signature matches
no IPR
Unintegrated signatures
-
-
-
mobidb-lite (disord...)
Protein sequence
>MIA_03760_1 MSSSSSAAVPAPIPNPASAGPDSSAQPPTATAPAPHESRSRDFSPHRAFKRPRLLEDNTLSSPSSSSALPSAALSPASSE ASSPSSSSSAAAADSRTKVLVAELTRQYFGSKKLDSHIPIPAFNFSSKPPADSASSSSASLSSSTSLDSSDPSDISSDTI TTATAILKDPPPVISAFKVVRIRAPQNKHIIRTGEPNFVKIFDSPLEETPVSTAQPTSQKRPPKTSSEGYISVPTILNTI SERLKKPQGEDLEQEEGESEDEEMEEEQEAVVNGENEEQAQEDEEMEEEEEDEDEDDEFFSYDPKVDMGHDALLEYMQNQ LNNGMPVDKATLRVEVSDKLARELKMFLWMNGPYSFIQKYVNSPLSKATLGEILAALSFPLPENLVTRTRSELLTSLVIL AVQYTVMPRKRLSNDMTIKSLVDIIDKAHNIIVLTGAGISTSLGIPDFRSKSGLYNKLAYLGLSDPQEVFDLGIFRQDPS IFYSIAKEILPVTTRFSPTHAFIKLLQDKGKLLRNYTQNIDNLEHYAGIRADKLVQCHGSFASATCQSCGYRTKGENLFE DIRNQIVSRCPKCKAAAAASLAAENKKKGSQQKDHKKGGGSGNKWVEKPGDTDDDDDDEDALGMSVTGLNIGKRVPTFGV MKPDITFFGEPLPHTFEDTLIGGDADRCDLLLCMGTSLKVSPVSETVRIVPPSVVQVYVSKTMITHNEFDLTLLGACDDV VEHLCNKLHWKLDHPMAANIDFTPYIERKPELAAYEFHEHPADAPKLQQLQDTAADDDEKRDVRIKKERDMPVTQRSLDS YFSNK
GO term prediction
Biological Process
None predicted.
Molecular Function
GO:0070403 NAD+ binding
Cellular Component
None predicted.