Protein

MIA_03737_1

Length
384 amino acids

Browser: contig04:2023695-2024850-

Protein function

EGGNOG:0PJ79Alanine dehydrogenase/PNT, C-terminal domain
SGD closest match:S000004918ADH2Alcohol dehydrogenase 2
CGD closest match:CAL0000177934ADH5Adh5p

Protein alignments

%idAln lengthE-value
MCA_06003_170.746%3351.69e-168MCA_06003_1
UniRef50_A2V8B370.746%3352.85e-165N-benzyl-3-pyrrolidinol dehydrogenase n=1 Tax=Magnusiomyces capitatus TaxID=1095183 RepID=A2V8B3_9ASCO
A0A0J9YHL2_GEOCN55.786%3372.82e-129Similar to Saccharomyces cerevisiae YOL086C ADH1 Alcohol dehydrogenase OS=Geotrichum candidum GN=BN980_GECA01s06104g PE=3 SV=1
A0A060T2K2_BLAAD49.102%3345.85e-92ARAD1C32934p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C32934g PE=4 SV=1
A0A1E4TMA4_9ASCO48.338%3315.70e-91Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_56443 PE=3 SV=1
A0A1D8PS45_CANAL45.210%3341.03e-84Adh5p OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=ADH5 PE=3 SV=1
ADH2_YEAST29.480%3464.37e-35Alcohol dehydrogenase 2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ADH2 PE=1 SV=3
A0A167FJP5_9ASCO28.902%3463.63e-33Alcohol dehydrogenase ADH3 OS=Sugiyamaella lignohabitans GN=ADH3 PE=3 SV=1
Q6CGT5_YARLI29.799%3493.65e-30YALI0A16379p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_A16379g PE=3 SV=1
A0A1E3PCI4_9ASCO27.901%3622.23e-27Alcohol dehydrogenase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_48354 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.9737
Predicted cleavage: 41

Protein family membership

None predicted.

Domains and repeats

  1. Domain
  2. Domain
  3. Domain
1 50 100 150 200 250 300 350 384

Detailed signature matches

  1. Domain IPR011032
    GroES-like
    1. SSF50129 (GroES-like)
  2. Domain IPR020843
    Polyketide synthase, enoylreductase domain
    1. SM00829 (PKS_ER_nam...)
  3. Domain IPR013154
    Alcohol dehydrogenase, N-terminal
    1. PF08240 (ADH_N)
  4. Domain IPR016040
    NAD(P)-binding domain
    1. SSF51735 (NAD(P)-bi...)
  5. Domain IPR013149
    Alcohol dehydrogenase, C-terminal
    1. PF00107 (ADH_zinc_N)
  6. SITE IPR002328
    Alcohol dehydrogenase, zinc-type, conserved site
    1. PS00059 (ADH_ZINC)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:3.40.50...
  2. G3DSA:3.90.18...
  3. NON_CYTOPLASM... (N...)
  4. SIGNAL_PEPTIDE (Sig...)
  5. SIGNAL_PEPTID... (S...)
  6. SIGNAL_PEPTID... (S...)
  7. SIGNAL_PEPTID... (S...)
  8. cd08254 (hydroxyacy...)

Residue annotation

  1. catalytic Zn bindi...
  2. putative NAD(P) bi...
  3. structural Zn bind...

Protein sequence

>MIA_03737_1
MLSKTIRLSSSASLLRSSLSASKRFSLPQSRLISPSAFIARAKMSTDTVVPPLQTAFIYHPGQFELEQKEIPVPAPAPGH
VLLKVVAAGVCHSDLHVLDGSLPYPDGLILGHEVVGTIVGYGDGVSKESYPAGPLFAIHGPNPCGICKHCRTGADNLCQE
PTRSHMGLGTPGGYEQYTQVNPRNLTLVPEGISPAVAAVSTDAVLTPYHALKRAKVNGLTRLLIIGLGGLGINGVQVAKA
FGAHVTAVDFKESSRELAKSFGADVVYDKLPEESLDVDVVADFVGAQATFDLAQKHVKTAGLIMPVGLGATHLSFDLGVF
AFKEFEILGNFWGTSEDQVEVFDLVKKGLVTPQVETTSYLNVNTVLKNLHDGNVKSRMVLVHED

GO term prediction

Biological Process

GO:0055114 oxidation-reduction process

Molecular Function

GO:0008270 zinc ion binding
GO:0016491 oxidoreductase activity

Cellular Component

None predicted.