Protein

MCA_06003_1

Length
393 amino acids

Gene name: BPD1

Description: N-benzyl-3-pyrrolidinol dehydrogenase

Browser: contigD:3008781-3009963+

RNA-seq: read pairs 52844, FPKM 1657.2, percentile rank 97.5% (100% = highest expression)

Protein function

Annotation:BPD1N-benzyl-3-pyrrolidinol dehydrogenase
KEGG:K13953adhP alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1]
EGGNOG:0PJ79Alanine dehydrogenase/PNT, C-terminal domain
SGD closest match:S000005446ADH1Alcohol dehydrogenase 1
CGD closest match:CAL0000177934ADH5Adh5p

Protein alignments

%idAln lengthE-value
UniRef50_A2V8B3100.00%3400.0N-benzyl-3-pyrrolidinol dehydrogenase n=1 Tax=Magnusiomyces capitatus TaxID=1095183 RepID=A2V8B3_9ASCO
MIA_03737_170.75%3351e-166MIA_03737_1
A0A0J9YHL2_GEOCN54.25%3415e-120Similar to Saccharomyces cerevisiae YOL086C ADH1 Alcohol dehydrogenase OS=Geotrichum candidum GN=BN980_GECA01s06104g PE=3 SV=1
A0A1E4TMA4_9ASCO48.79%3301e-87Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_56443 PE=3 SV=1
A0A1D8PS45_CANAL45.51%3343e-82Adh5p OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=ADH5 PE=3 SV=1
A0A060T2K2_BLAAD44.51%3371e-77ARAD1C32934p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C32934g PE=4 SV=1
ADH1_YEAST29.48%3463e-31Alcohol dehydrogenase 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ADH1 PE=1 SV=5
ADH2_YARLI31.59%3451e-27Alcohol dehydrogenase 2 OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=ADH2 PE=1 SV=1
A0A1E3PCI4_9ASCO28.77%3513e-25Alcohol dehydrogenase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_48354 PE=3 SV=1
A0A167FJP5_9ASCO28.00%3506e-25Alcohol dehydrogenase ADH3 OS=Sugiyamaella lignohabitans GN=ADH3 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.9930
Predicted cleavage: 37

Protein family membership

None predicted.

Domains and repeats

  1. Domain
  2. Domain
  3. Domain
1 50 100 150 200 250 300 350 393

Detailed signature matches

  1. Domain IPR011032
    GroES-like
    1. SSF50129 (GroES-like)
  2. Domain IPR020843
    Polyketide synthase, enoylreductase domain
    1. SM00829 (PKS_ER_nam...)
  3. Domain IPR013154
    Alcohol dehydrogenase, N-terminal
    1. PF08240 (ADH_N)
  4. Domain IPR016040
    NAD(P)-binding domain
    1. SSF51735 (NAD(P)-bi...)
  5. Domain IPR013149
    Alcohol dehydrogenase, C-terminal
    1. PF00107 (ADH_zinc_N)
  6. SITE IPR002328
    Alcohol dehydrogenase, zinc-type, conserved site
    1. PS00059 (ADH_ZINC)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:3.40.50...
  2. G3DSA:3.90.18...
  3. cd08254 (hydroxyacy...)

Residue annotation

  1. catalytic Zn bindi...
  2. putative NAD(P) bi...
  3. structural Zn bind...

Protein sequence

>MCA_06003_1
MLSLQKSRIAVPLVRSVSSSLSIIAYRSAIRYTPRPTTSINTQKQFHSSQLLKMAEIPEKQTAFVFKNGSFALEKKEIEV
PKPDAGKVLLKVAAAGVCHSDLHVLHGGLPYPDGLILGHEIAGHIVAYGDGVDKAAFPSDALYAVVGPNPCGMCKACRTG
ADNVCEDPSRTHMGLGSPGGYEQYTQVSARNITKVPEGIPAAVAAASTDAVLTPYHALKRAGINGMTRLLIVGLGGLGIN
AVQIAKAFGSYVIAVDPKESSRDLAKQYGANEVYAKLPEESLDVDVAADFYGSQGTFDLCQKHVKAQGILLPVGLQDPKI
TFDLNHLAFREYTIIGNFWGTSQDQTEVFELVKKGLVTPQVETTSWLNVNKVLKDLDEGKIKSRMVLVHNEDN

GO term prediction

Biological Process

GO:0055114 oxidation-reduction process

Molecular Function

GO:0008270 zinc ion binding
GO:0016491 oxidoreductase activity

Cellular Component

None predicted.