Protein

MIA_03632_1

Length
518 amino acids

Browser: contig04:1749441-1751042-

Protein function

EGGNOG:0PG8APGUG_02497K14675 TAG lipase lysophosphatidylethanolamine acyltransferase EC 3.1.1.3 2.3.1
SGD closest match:S000004930TGL3Lipase 3
CGD closest match:CAL0000175330orf19.4699Bifunctional triglyceride lipase/lysophosphatidylethanolamine acyltransferase

Protein alignments

%idAln lengthE-value
A0A060T8F5_BLAAD38.370%5031.25e-75ARAD1D06072p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D06072g PE=4 SV=1
UniRef50_A0A060T8F538.370%5033.09e-72ARAD1D06072p n=2 Tax=Blastobotrys adeninivorans TaxID=409370 RepID=A0A060T8F5_BLAAD
A0A1E3PT29_9ASCO30.341%5576.09e-58Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_31053 PE=4 SV=1
A0A0J9X5Q2_GEOCN39.140%4421.04e-57Similar to Saccharomyces cerevisiae YMR313C TGL3 Bifunctional enzyme with triacylglycerol lipase and lysophosphatidylethanolamine acyltransferase activity OS=Geotrichum candidum GN=BN980_GECA03s07072g PE=4 SV=1
MCA_05747_139.828%3491.14e-52MCA_05747_1
A0A167D2G3_9ASCO42.149%2421.51e-42Tgl3p OS=Sugiyamaella lignohabitans GN=TGL3 PE=4 SV=1
A0A1E4THP2_9ASCO29.142%5016.06e-40Uncharacterized protein (Fragment) OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_11616 PE=4 SV=1
Q6C8R8_YARLI33.770%3054.83e-37YALI0D17534p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_D17534g PE=4 SV=1
A0A1D8PL60_CANAL34.231%2602.27e-36Bifunctional triglyceride lipase/lysophosphatidylethanolamine acyltransferase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.4699 PE=4 SV=1
TGL3_YEAST28.267%3752.92e-32Lipase 3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=TGL3 PE=1 SV=2

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.9871
Predicted cleavage: 48

Protein family membership

Domains and repeats

  1. Domain
1 50 100 150 200 250 300 350 400 450 518

Detailed signature matches

  1. Family IPR021771
    Triacylglycerol lipase
    1. PF11815 (DUF3336)
  2. Domain IPR016035
    Acyl transferase/acyl hydrolase/lysophospholipase
    1. SSF52151 (FabD/lyso...)
  3. Domain IPR002641
    Patatin-like phospholipase domain
    1. PS51635 (PNPLA)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:3.40.10...
  2. NON_CYTOPLASM... (N...)
  3. SIGNAL_PEPTIDE (Sig...)
  4. SIGNAL_PEPTID... (S...)
  5. SIGNAL_PEPTID... (S...)
  6. SIGNAL_PEPTID... (S...)
  7. TMhelix

Protein sequence

>MIA_03632_1
MNSLPARNQIKPLLVLLLLALLARVLALVRALVRTLARPLRPQPSRAAAYALDAALANDRWRRAPESRLYDHNLIAARKA
HLAAARQSGRANDLATALRAGLLRNIGSIAAPQLYARAHAGTKLLIEAYIAEVIRGLQLLAQTPLPSAQDVPRPANSMLA
SQQQRADFFRDTRQAFGRSALVLRGGAIFGLAHLGVARALLLHGLLPKIVAGAGASALPAALLGAVPESDLLSTIDSIVS
HTTPLTSLYSCEMSAFAQFLYAMLAQTTFEEAHKLSGRALNIAIAPSSPSMPRLLNHLVSPSVTVASAVAVSLGPSGPRP
SSAPPTLLCKDHNGLITSYAALVLPPDAPQPTYTRASLTEEAPPVHPKRDSPYTRMTELFNVNNLLVSAAPPHLPKTSFS
PPFLPSRVARAARIVCLHRLRWLARAAGMSPGLRAALFPDPAPPDSRAGGCTGLALTIAPEPPGSQGLLAALIQAFDSAP
LNAAQTIAAGEKAVWPHLQIIWARCAIEFVLDDLCNGL

GO term prediction

Biological Process

GO:0006629 lipid metabolic process
GO:0008152 metabolic process

Molecular Function

GO:0004806 triglyceride lipase activity

Cellular Component

None predicted.