Protein

MCA_05747_1

Length
992 amino acids

Gene name: TGL3

Description: Lipase 3

Browser: contigD:2233185-2236229-

RNA-seq: read pairs 413, FPKM 5.1, percentile rank 17.6% (100% = highest expression)

Protein function

Annotation:TGL3Lipase 3
KEGG:K14675TGL3 TAG lipase / lysophosphatidylethanolamine acyltransferase [EC:3.1.1.3 2.3.1.-]
EGGNOG:0PG8APGUG_02497K14675 TAG lipase lysophosphatidylethanolamine acyltransferase EC 3.1.1.3 2.3.1
SGD closest match:S000004930TGL3Lipase 3
CGD closest match:CAL0000175330orf19.4699Bifunctional triglyceride lipase/lysophosphatidylethanolamine acyltransferase

Protein alignments

%idAln lengthE-value
Q6C8R8_YARLI38.91%6633e-122YALI0D17534p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_D17534g PE=4 SV=1
UniRef50_Q6C8R838.91%6637e-119YALI0D17534p n=2 Tax=Yarrowia lipolytica TaxID=4952 RepID=Q6C8R8_YARLI
A0A1E3PT29_9ASCO36.02%7192e-113Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_31053 PE=4 SV=1
A0A0B5ABR9_BLAAD44.60%4358e-106Uncharacterized protein OS=Blastobotrys adeninivorans PE=4 SV=1
A0A0J9X5Q2_GEOCN46.01%4267e-98Similar to Saccharomyces cerevisiae YMR313C TGL3 Bifunctional enzyme with triacylglycerol lipase and lysophosphatidylethanolamine acyltransferase activity OS=Geotrichum candidum GN=BN980_GECA03s07072g PE=4 SV=1
A0A1D8PL60_CANAL36.94%5557e-92Bifunctional triglyceride lipase/lysophosphatidylethanolamine acyltransferase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.4699 PE=4 SV=1
A0A167D2G3_9ASCO44.42%4124e-81Tgl3p OS=Sugiyamaella lignohabitans GN=TGL3 PE=4 SV=1
MIA_03632_139.83%3492e-55MIA_03632_1
A0A1E4THP2_9ASCO34.33%4021e-51Uncharacterized protein (Fragment) OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_11616 PE=4 SV=1
TGL3_YEAST28.57%4412e-44Lipase 3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=TGL3 PE=1 SV=2

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0141

Protein family membership

Domains and repeats

  1. Domain
1 100 200 300 400 500 600 700 800 900 992

Detailed signature matches

  1. Family IPR021771
    Triacylglycerol lipase
    1. PF11815 (DUF3336)
  2. Domain IPR016035
    Acyl transferase/acyl hydrolase/lysophospholipase
    1. SSF52151 (FabD/lyso...)
  3. Domain IPR002641
    Patatin-like phospholipase domain
    1. PS51635 (PNPLA)
    2. PF01734 (Patatin)
Unintegrated signatures no IPR
Unintegrated signatures
  1. CYTOPLASMIC_D... (C...)
  2. G3DSA:3.40.10...
  3. NON_CYTOPLASM... (N...)
  4. TMhelix
  5. TRANSMEMBRANE (Tran...)
  6. mobidb-lite (disord...)

Protein sequence

>MCA_05747_1
MNSNIGSNEEDSVNNEQKNTIYDASSGNTPSSNTNSSNCSPSPSPSPKVSSILMATTPTSKTPLAGSQNSSSSNLEATPS
SAVSQISTSNKNSSGNHLSLYSSPLSPRSPHSPHSTVIEFSAASSITEPLLRLQKQQQQQLASSSSMHNHTSNVSGSSKN
NKKFQNMHFANDSNNYINHNSGYLYHQHHQWNHLQHSNNSNSSASNLAAMMHPTSASHSTSTSNSNSNPFNIYSSELNNS
HTQTAIPQHFEKSTSLLAEPSPTAYSSTRLAYSNSSSLNAGGPGGLYMLDNNKDENEEKYNKYYSKKNRPTSKSFLFRQI
IWIIGALITVLIDVFQFWNTRIQNYLIPRAFRSGVEETETNDDILSIINNKKISEKEQLSILKRKIGSAKNFEEWEHMAY
RIDSILGNDLWRQNPASKKYDYRLISTRLKHLIQARQDENTHELVTALRSGLLRNLGSLGNSDLYNRAYSGTKLLIEDYI
SEVLKCLEYLDNLPTTSNQYFLHSNSTSNPNLENSNQLVKRNNTEASPYASFATHQQKLDFFHDTRQSFGRTALVLHGGS
LFGMCHLGVVKVLCLQGLLPKIISGTTVGAIIAALICSHSDDELLPILDNVSRILPQYYNQDEDDVNENEDDSVKFYSNV
ERVLKSSYPSEIILLEKYVSDHLGDLTFEEAYIKSDRALNIMITPSDPSMPKLLNYLTTPHVIIRTAVNASIGTGIIHKE
VELLIKNHLGKIVPFNMFMRPPNAKAPINSQALVRPPTNASLSTSFNLNSTGTNKRGDTENSNSHESTTGQDNDGGYNSE
TDLDNDDDYNSDRYRSKIFYTPSNCTVYTDRESPYTKLSELFNVNNFIVSLARPYLASLFAGEQNYKGYGGILPKLSRVL
KYEIQHRLRQLARLGLLPEIVQRFFVDEKIPIVSGGGALEVTIVPELPSSSSIWRNIGKTFDTQNLHSKVEDLILMGERS
VWPVLQLIWARCAIEYVLDDMYNVARKGNSRR

GO term prediction

Biological Process

GO:0006629 lipid metabolic process
GO:0008152 metabolic process

Molecular Function

GO:0004806 triglyceride lipase activity

Cellular Component

None predicted.