Protein

MIA_03596_1

Length
487 amino acids

Browser: contig04:1650055-1651519+

Protein function

EGGNOG:0PIXIYPS1protease
SGD closest match:S000004111YPS3Aspartic proteinase yapsin-3
CGD closest match:CAL0000193807SAP5Candidapepsin-5

Protein alignments

%idAln lengthE-value
MCA_05419_167.07%4101e-177MCA_05419_1
A0A060T2Y9_BLAAD42.69%3354e-73ARAD1C28688p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C28688g PE=3 SV=1
UniRef50_A0A060T2Y942.69%3351e-69ARAD1C28688p n=1 Tax=Blastobotrys adeninivorans TaxID=409370 RepID=A0A060T2Y9_BLAAD
A0A167FDB7_9ASCO34.95%3924e-49Yps3p OS=Sugiyamaella lignohabitans GN=YPS3 PE=3 SV=1
Q6CBB7_YARLI30.22%4072e-44YALI0C20273p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_C20273g PE=3 SV=1
A0A1E3PJQ9_9ASCO35.29%4085e-43Acid protease OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_46336 PE=3 SV=1
M1XFD0_GEOCN32.91%3922e-40Aspartic protease OS=Geotrichum candidum GN=YSP3 PE=3 SV=1
CARP5_CANAL31.07%4288e-39Candidapepsin-5 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=SAP5 PE=1 SV=1
YPS3_YEAST29.27%4273e-34Aspartic proteinase yapsin-3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YPS3 PE=1 SV=1
A0A1E4TI13_9ASCO24.65%3571e-18Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_123212 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.1321

Protein family membership

Domains and repeats

  1. Domain
1 50 100 150 200 250 300 350 400 450 487

Detailed signature matches

  1. Family IPR001461
    Aspartic peptidase A1 family
    1. PR00792 (PEPSIN)
  2. Domain IPR021109
    Aspartic peptidase domain
    1. G3DSA:2.40.70.10
    2. SSF50630 (Acid prot...)
  3. Domain IPR033121
    Peptidase family A1 domain
    1. PS51767 (PEPTIDASE_A1)
    2. PF00026 (Asp)
  4. Domain IPR033876
    Secreted aspartic endopeptidase
    1. cd05474 (SAP_like)
  5. SITE IPR001969
    Aspartic peptidase, active site
    1. PS00141 (ASP_PROTEASE)
Unintegrated signatures no IPR
Unintegrated signatures
  1. NON_CYTOPLASM... (N...)
  2. SIGNAL_PEPTIDE (Sig...)
  3. SIGNAL_PEPTID... (S...)
  4. SIGNAL_PEPTID... (S...)
  5. SIGNAL_PEPTID... (S...)
  6. SignalP-noTM

Residue annotation

  1. inhibitor binding ...
  2. catalytic residue ...
  3. catalytic motif cd...
  4. Active site flap c...

Protein sequence

>MIA_03596_1
MKFSLLAITTFASIVFAAPFTNENPGFVKAQLTKREFKDPSVSQLFRRGQVNTPLYNQISYYQIDLDVGNPPQKLQALLD
TGSSDMWFFSNYLGAGSAPTFSPQRSNTWHNNYTQFTISYVSGSAQGTWGTDEVSISGSKIKGQSFAIVTSGNGLTGIPG
LIGTGLPALESTNNNFNFFQPRHTYSNVPLSLFEQGHIGTPTYSLYLDTIDAKAGTVLFGAIDHSKYKGNMYSVPRVHNS
RFNINIDDIQVNGRSVGSSSSATLDSGTTLGSLPDSVISSLVSSLGLQQDYSNNGIYYARRNSFKGDTPLTFSVSGVKFN
LKASDLFIDSEKLGDPFPAGLSILGFSPASQTQGQVILGDVFLRNFYIVYDLGNPQLGMALANFNHTSVPQFEPITTSVI
PRSQAVSASKKIAAQPAQNTPANPLAGLFGPFRGLFGNGLFGNGLLSPKQASVEEKLDVSDSETNTEEAIKLVKKSIEDQ
LLVFEKN

GO term prediction

Biological Process

GO:0006508 proteolysis

Molecular Function

GO:0004190 aspartic-type endopeptidase activity

Cellular Component

None predicted.