Protein

MCA_05419_1

Length
531 amino acids

Gene name: YPS3B

Description: aspartic protease

Browser: contigD:1279971-1281567-

RNA-seq: read pairs 2, FPKM 0.0, percentile rank 2.4% (100% = highest expression)

Protein function

Annotation:YPS3Baspartic protease
EGGNOG:0PIXIOPSBprotease
SGD closest match:S000004111YPS3Aspartic proteinase yapsin-3
CGD closest match:CAL0000201140SAP10Candidapepsin-10

Protein alignments

%idAln lengthE-value
MIA_03596_165.31%4180.0MIA_03596_1
A0A060T2Y9_BLAAD46.06%3431e-95ARAD1C28688p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C28688g PE=3 SV=1
UniRef50_A0A060T2Y946.06%3432e-92ARAD1C28688p n=1 Tax=Blastobotrys adeninivorans TaxID=409370 RepID=A0A060T2Y9_BLAAD
A0A167FDC7_9ASCO34.90%3843e-60Yps1p OS=Sugiyamaella lignohabitans GN=YPS1 PE=3 SV=1
Q6CBB7_YARLI33.43%3441e-56YALI0C20273p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_C20273g PE=3 SV=1
M1XFD0_GEOCN33.41%4162e-49Aspartic protease OS=Geotrichum candidum GN=YSP3 PE=3 SV=1
A0A1E3PJQ9_9ASCO32.08%4245e-48Acid protease OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_46336 PE=3 SV=1
YPS3_YEAST31.09%4028e-43Aspartic proteinase yapsin-3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YPS3 PE=1 SV=1
CAR10_CANAL30.39%3852e-38Candidapepsin-10 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=SAP10 PE=1 SV=1
A0A1E4TI13_9ASCO27.25%3451e-26Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_123212 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.2418

Protein family membership

Domains and repeats

  1. Domain
1 50 100 150 200 250 300 350 400 450 500 531

Detailed signature matches

  1. Family IPR001461
    Aspartic peptidase A1 family
    1. PR00792 (PEPSIN)
  2. Domain IPR021109
    Aspartic peptidase domain
    1. G3DSA:2.40.70.10
    2. SSF50630 (Acid prot...)
  3. Domain IPR033121
    Peptidase family A1 domain
    1. PS51767 (PEPTIDASE_A1)
    2. PF00026 (Asp)
  4. Domain IPR033876
    Secreted aspartic endopeptidase
    1. cd05474 (SAP_like)
  5. SITE IPR001969
    Aspartic peptidase, active site
    1. PS00141 (ASP_PROTEASE)
Unintegrated signatures no IPR
Unintegrated signatures
  1. NON_CYTOPLASM... (N...)
  2. SIGNAL_PEPTIDE (Sig...)
  3. SIGNAL_PEPTID... (S...)
  4. SIGNAL_PEPTID... (S...)
  5. SIGNAL_PEPTID... (S...)
  6. SignalP-noTM
  7. mobidb-lite (disord...)

Residue annotation

  1. inhibitor binding ...
  2. catalytic residue ...
  3. catalytic motif cd...
  4. Active site flap c...

Protein sequence

>MCA_05419_1
MKFLVISVASLASTVLAAPGGFKYIKADLKKRTIEDDSAQQLMRRGMINTPLYNQVQFYQIDMDVGNPPQKLSALLDTGS
SDMWFFSSGVPGATAHFNPRQSSTWQNNNTQFTIGYVSGNARGTWGTDDVSISGAKIKKQSFALVTQGNGLSGLPGLIGV
GLPALESTNVNYNFLGGPKRTYSNVPISLFEQGHITTPTYSMFLDNIDATAGTVLFGAIDHSKYKGTLYSVPRVHNSRFN
VNVDNFSVNGQSIGSIGSATLDSGTTLGSLPDSIINSLARSLRLQQSQGVYYARKNSYNPNTPISFSISGAQFNLKMGDL
FVDSEKLGDSFPKGLSVFGFTPASTTQNQIILGDVFLRNFYIVYDLAHPQIGVALANFDHKNKSNMEPIVTSTIPKARLV
TASPAGNSASSSNTQSAYRNSSGNIFGWLTGGLRNLFPSTYQSALINFRNSLASKTTSFAASVAPSSLNLNDKNSEDPAA
ISEPSVIPYPSTKNMEDGEPKINIVDLQNSFSGQPNQLNLVDLDSSYSSEH

GO term prediction

Biological Process

GO:0006508 proteolysis

Molecular Function

GO:0004190 aspartic-type endopeptidase activity

Cellular Component

None predicted.