Protein

MIA_03590_1

Length
1,480 amino acids


Browser: contig04:1632788-1637349+

Protein function

EGGNOG:0PFN7PGUG_04203(ABC) transporter
SGD closest match:S000005679PDR5Pleiotropic ABC efflux transporter of multiple drugs
CGD closest match:CAL0000197349CDR2Multidrug resistance protein CDR2

Protein alignments

%idAln lengthE-value
MCA_02576_163.765%14820.0MCA_02576_1
A0A0J9XKE4_GEOCN61.806%14400.0Similar to Saccharomyces cerevisiae YDR011W SNQ2 Plasma membrane ATP-binding cassette (ABC) transporter OS=Geotrichum candidum GN=BN980_GECA23s00131g PE=3 SV=1
A0A060T914_BLAAD56.733%14630.0ARAD1D07634p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D07634g PE=3 SV=1
UniRef50_A0A060T91456.733%14630.0ARAD1D07634p n=220 Tax=Dikarya TaxID=451864 RepID=A0A060T914_BLAAD
Q6CBB8_YARLI53.446%14800.0YALI0C20265p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_C20265g PE=3 SV=1
A0A1E4TEV9_9ASCO51.628%15050.0Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_103973 PE=3 SV=1
A0A161HI40_9ASCO52.507%14760.0ATP-binding cassette multidrug transporter PDR5 OS=Sugiyamaella lignohabitans GN=PDR5 PE=3 SV=1
CDR2_CANAL49.329%14900.0Multidrug resistance protein CDR2 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=CDR2 PE=3 SV=2
PDR5_YEAST48.623%14890.0Pleiotropic ABC efflux transporter of multiple drugs OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PDR5 PE=1 SV=1
A0A1E3PD79_9ASCO42.982%13680.0Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_84369 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0037

Protein family membership

None predicted.

Domains and repeats

1 200 400 600 800 1000 1200 1480

Detailed signature matches

    1. PF14510 (ABC_trans_N)
    1. PF00005 (ABC_tran)
    2. PS50893 (ABC_TRANSP...)
    1. cd03233 (ABCG_PDR_d...)
    1. SSF52540 (P-loop co...)
    1. SM00382 (AAA_5)
    1. PF01061 (ABC2_membrane)
    1. PF06422 (PDR_CDR)
    1. cd03232 (ABCG_PDR_d...)
    1. PS00211 (ABC_TRANSP...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. TRANSMEMBRANE (Tran...)
  2. mobidb-lite (disord...)

Protein sequence

>MIA_03590_1
MSKEDANEELGSPQPYYDKDNDLSSEREAPSEEEKNEAIHELARQYTHTSGLSRTQTNTSLLLAPIPTNFNPFLSQDNPI
LDPLSLEFNPRAWARHMLKIRHSDPEKYPKLNAGVSFKNLGAYGYSGGTSFQPTVFNTIIQRANDYLNFIRRRKGEKVTI
LKHFNGLVKSGETCVVLGRPGAGCSTLLKTISCDTYGFHITDESLINYQGITPEQVVKNYRGEVVYNAENEIHFPHLSVG
DTLKFAALARTPENRLPGVTRDQHATHVRDVVMTMFGLLHTMNTRVGNDFIRGVSGGERKRVSIAEVVLAGSAIQAWDNA
TRGLDSATALSFVKSLKIDADLGGASIFVSLYQASQDAYDLFDKVTVLYLGRQIFFGPTTEAKKFFEDMGYVCIDRQTTG
DFLTSLTSPSERVVKPGFEHLVPRTPDEFEDYWQKSPQYKKLIEEIDEWNNEHPIGGPGADKFKEFKTTQQAKFVPSSSP
YFISYPMQIRICITRGFQRLKGDPAMTLTTIFGNTIAALIVSSIFYNQPKTTHSFYFRSAALFFSVLFNTLSSLLEVFAL
YAIRPIVEKHNRYAFYRPSAEAISSLIVDMPGKVLTSLAFNLVLYFMVNLKRTPAAFFTYFLFSFLTSLTSSFLFRLIAS
VTRTVSEALTPSALVIFLIVVTTGFVIPVVDMHPWVRWINYLNPTAYVFEAVMVNEFRSVYYECSSMIPSGPGYEDIPQE
LQLCSVIGAVPGSNIVYGNDYVIQSFKYYPSHLWRNLGILIGFCVFFYLLYMLFSELVKGQRSRGEILIFPRGVKIPVPQ
ARDVETLEKGMADDNNLDTPAIRVQSSIKLQKQEGIFQWQDVCYDIKIKGEPRRLLDHVDGWVKPGTLTALMGSSGAGKT
TLLDTLADRVTMGVVTGDMLVNGSPRDRSFQRKTGYVQQQDVHLDTTTVREALEFSALLRQPDEIPRAEKIAYVNEVIKI
LEMEDYADAVVGVPGEGLNVEQRKRLTIGVELAAKPELLLFLDEPTSGLDSQTAWSIVSLMKKLTNSGQAILCTIHQPSA
VLFQQFDRLMFLKKGGQTVYYGDIGENAETLVKYFVKNGAHPCPPDANPAEWMLEVIGAAPGSHTDKDWFEVWRNSEEYQ
IVKRDLEALREESTMYLDKSGSKSMAKTYAVPIWKQCIIVSTRSLKHTWRNPQYIWSKLILCVTSPFFLGVTFWKAKNTL
QGLQNQMFAVFMITVVFPPLVEQMMSPFSLQRMLYETRERPSKTYSWVTFITSMIVSEIPWQTIAALGTFFTFYYPVGFY
RNAIPTDGVHERGALFFLMVLWYFYYMLTFSYMAVATLTEETASNISNVLFNVALSMCGVLVPKDQLPGFWIFMYRCSPF
TYIISALLSTGIAHSEVKCDAKELLHFATTPNSTMTCGEFLGPYADATGGVVNNPSSYTDCQFCTMKSTDTYLASIYAPL
SQAWRNFGLLIAFTFINLAFAYFFYWLGRVPKSWGKKKKD

GO term prediction

Biological Process

GO:0006810 transport

Molecular Function

GO:0005524 ATP binding
GO:0016887 ATPase activity
GO:0042626 ATPase activity, coupled to transmembrane movement of substances

Cellular Component

GO:0016020 membrane
GO:0016021 integral component of membrane