Protein
MCA_02576_1
Length
1,465 amino acids
Gene name: PDR5D
Description: plasma membrane ATP-binding cassette (ABC) transporter; involved in multidrug resistance
Browser: contigB:1700190-1704784+
RNA-seq: read pairs 588, FPKM 5.0, percentile rank 17.3% (100% = highest expression)
Protein function
| Annotation: | PDR5D | plasma membrane ATP-binding cassette (ABC) transporter; involved in multidrug resistance | |
|---|---|---|---|
| EGGNOG: | 0PFN7 | PGUG_04203 | (ABC) transporter |
| SGD closest match: | S000005679 | PDR5 | Pleiotropic ABC efflux transporter of multiple drugs |
| CGD closest match: | CAL0000201396 | CDR4 | Cdr4p |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MIA_03590_1 | 63.77% | 1482 | 0.0 | MIA_03590_1 |
| A0A0J9XKE4_GEOCN | 59.60% | 1433 | 0.0 | Similar to Saccharomyces cerevisiae YDR011W SNQ2 Plasma membrane ATP-binding cassette (ABC) transporter OS=Geotrichum candidum GN=BN980_GECA23s00131g PE=3 SV=1 |
| A0A060T914_BLAAD | 55.10% | 1452 | 0.0 | ARAD1D07634p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D07634g PE=3 SV=1 |
| UniRef50_A0A060T914 | 55.10% | 1452 | 0.0 | ARAD1D07634p n=220 Tax=Dikarya TaxID=451864 RepID=A0A060T914_BLAAD |
| A0A1E4TEV9_9ASCO | 52.62% | 1412 | 0.0 | Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_103973 PE=3 SV=1 |
| Q6CFY4_YARLI | 52.55% | 1450 | 0.0 | YALI0B02544p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_B02544g PE=3 SV=1 |
| A0A161HI40_9ASCO | 50.48% | 1462 | 0.0 | ATP-binding cassette multidrug transporter PDR5 OS=Sugiyamaella lignohabitans GN=PDR5 PE=3 SV=1 |
| A0A1D8PE84_CANAL | 49.82% | 1425 | 0.0 | Cdr4p OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=CDR4 PE=3 SV=1 |
| PDR5_YEAST | 50.56% | 1426 | 0.0 | Pleiotropic ABC efflux transporter of multiple drugs OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PDR5 PE=1 SV=1 |
| A0A1E3PD79_9ASCO | 42.17% | 1385 | 0.0 | Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_84369 PE=3 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.1140
Protein family membership
None predicted.
Domains and repeats
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Domain
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Domain
1
200
400
600
800
1000
1200
1465
Detailed signature matches
no IPR
Unintegrated signatures
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CYTOPLASMIC_D... (C...)
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NON_CYTOPLASM... (N...)
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TRANSMEMBRANE (Tran...)
Protein sequence
>MCA_02576_1 MSDKASDVIEQYSGPGSFYSLNDEKNVENDAIIEIARTYTNASLKSTTTIPVSENPFLGTSNNPLLDPYSDSFSSKEWTK HFYKLQRADPQRFPQLEMGVSFKNLGAYGYEGGTNYQKTVANMLMYVPQKIYTTIFKRNSQENKTQILNNFNGLLRSGET CVVLGRPGAGCSTFLKSIASDTYGFHMDKSTFLNYQGLSSEDIKKHYRGEVIFNAENEVHIPHLTVGDTLKFAALARTPE SRFEGVTRDQHATYLRDVTMATFGLLHTMNTKVGNDFIRGVSGGERRRISISEVVIASSQIQCFDNSTRGLDSATALEFI KSVKVDAEVSGAAIFVSLYQASQDAYDLFDKATVLYLGKQIYYGPANKAKKFFEDMGYVCIDRQTTGDFLTSLTSPSERV VKPGYEKKVPRTPEEFEAYWMASPEYAALIEEVDQWNAEHPLNNPQITEKIEAYKRSRQSSFARLSSPYFLSYPQQVGIC VTRGIQRLKADYTMLLSTIIGDIIAALLVSSIFYNQPKNSGSFYFRGASIFFAVLFNSLSSLLEVFALYLIRPIAEKHHK YSFYHPSAEAISSQIVDMPGKIISSLAFNLVLYFMVNLKRTVGGFFTFYLFGFMIILTMSALFRTIASLTRTISEAMTPA SFAISILITTTGFIIPVVDMHPWIRWLNYVNPLSYCFEAMMINEFRNTRFPCSEFVPSGELYDNLPLEYKRCSVVGSKLG EADVSGADYIIQSFEYMPNHLWRNLGIVIAFCVIYHLLYFFFTEFIKGQRSKGEVLVFQRGNKAAATSFKEQQIEDNYNG LESSSDKEEKTNIKLQQSGIYQWEDVCYDIKIKGEPRRLLDHVDGWVKPGTLTALMGASGAGKTTLLDTLADRVTMGVVT GSMLVNGHQRDASFQRKTGYAQQQDIHLPTSTVREALEFSALLRQPDTYTKEEKLAYVDEVIKILEMEKYSDAVVGIPGE GLNVEQRKRLTIGVELAARPELLLFLDEPTSGLDSQTAWSIMMLMKKLTNSGQAILCTIHQPSAVLFQQFDRLLLLKRGG QTVYYGDLGEGATKMISYFERNGAPKCPPDANPAEWMLYAIGAAPGSHTDNDWHEVWKNSPEYAQTKQELRELAEQYKLE NPINDTDTTSQTYAVSIWKQIPIVSQRAFKKTWRDPQYIWAKLALAIGLNFFLGIAFWKAKNTIQGMQNQMYSIFMVIVV FVSVTQQLMVPFVEQRTLYETRERPSRTYSWVAFMSSMLIAEIPWALLAAVGSYFCFYYPVGLYNNASLAGETAERGALF FLLYVVFYLHSLTFGYMLVAALPDADTAGNLCVVLFNFSLSMAGVLAPKDTLPGFWIFMYRVSPFTYLIGAFLSTGIADG NIECSPVETMVYPQTPNSQTCEGFLGPYANATDGSIANPFATSNCEFCPMSSTNTYLDSIYAPYSNAWRNFGIIIGYIAF NTIMSYFFYWLGRVPKNFGKKKQGN
GO term prediction
Biological Process
GO:0006810 transport
Molecular Function
GO:0005524 ATP binding
GO:0016887 ATPase activity
GO:0042626 ATPase activity, coupled to transmembrane movement of substances
Cellular Component
GO:0016020 membrane
GO:0016021 integral component of membrane