Protein

MIA_03555_1

Length
765 amino acids


Browser: contig04:1532579-1534910+

Protein function

EGGNOG:0PH5THEM14Protoporphyrinogen oxidase
SGD closest match:S000000816HEM14Protoporphyrinogen oxidase
CGD closest match:CAL0000182679HEM14Protoporphyrinogen oxidase

Protein alignments

%idAln lengthE-value
MCA_03199_148.038%8410.0MCA_03199_1
A0A0J9X7Z4_GEOCN48.054%7450.0Similar to Saccharomyces cerevisiae YER014W HEM14 Protoporphyrinogen oxidase, a mitochondrial enzyme that catalyzes the seventh step in the heme biosynthetic pathway OS=Geotrichum candidum GN=BN980_GECA04s01572g PE=4 SV=1
UniRef50_A0A0J9X7Z448.054%7450.0Similar to Saccharomyces cerevisiae YER014W HEM14 Protoporphyrinogen oxidase, a mitochondrial enzyme that catalyzes the seventh step in the heme biosynthetic pathway n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9X7Z4_GEOCN
A0A167DXS9_9ASCO31.957%7514.10e-107Oxygen-dependent protoporphyrinogen oxidase OS=Sugiyamaella lignohabitans GN=HEM14 PE=4 SV=1
A0A060T742_BLAAD33.282%6491.15e-96ARAD1C25718p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C25718g PE=4 SV=1
Q6C826_YARLI27.825%5931.93e-43Protoporphyrinogen oxidase OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_D23331g PE=3 SV=1
PPOX_YEAST25.213%5871.15e-31Protoporphyrinogen oxidase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=HEM14 PE=1 SV=1
A0A1D8PEF0_CANAL25.535%6076.80e-28Protoporphyrinogen oxidase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=HEM14 PE=3 SV=1
A0A1E3PSF4_9ASCO24.507%6085.53e-23Protoporphyrinogen oxidase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_49001 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.8650
Predicted cleavage: 28

Protein family membership

Domains and repeats

  1. Domain
  2. Domain
1 100 200 300 400 500 600 700 765

Detailed signature matches

    1. SSF51905 (FAD/NAD(P...)
    1. PF01593 (Amino_oxidase)
Unintegrated signatures no IPR
Unintegrated signatures

Protein sequence

>MIA_03555_1
MLRFQVAKVSSPALLSARYFSTTLVRCNAELSKKPTLQYLREPGDDPDRYLDENGTFGGRIIRPQDEQLFSHTNVLELID
RPEPALDLIPTLKRRKAISDPGLFASQEDADRAVAVLDRVNELGALPTWHQVTAKEYYNDFDDAQYDFETQLTKIQELKS
GDKVVVIGAGHSRPDLDITLLEKDDKVGGWMRTEKIVLPASLNQDPLDDEEPKERIEYNEWGPRTLQGGHLGSALVRIIL
TKLGVVDDVLKVVPKTSAANRKGLLHKGFPFQLPSSTGELFAFLSHPSITRGIKLAPFRDLLAPSRDPSVRDESVDSYVT
RRFGAKAAERFVSAIMRGIYAGDSGKLSARSVARLGKMYPTEVDNPSMLSSMISGSGRRSEMYAAHAQTLLAHAMVDLPF
EEVLKEMSKYSVGVFKDGIQSLAELLEKDLADNFKNVHILKRNTVLGIEKNPETSKITIKSKEETIGLEKEIDANWVVST
IPGYHVSNILKSTDAELSKQIDKSLTYSTVGVVNVTIPNKFIGKNWFGYLVPKEEDALGNNPHGLLGVIFNTAVRTAARD
INRIPLPHPFEAMTIQKKDSPQGESFLDNYDPHRYEDEHLRKVLFTDAPEFDKNQNPVVKEPPLPDHSNVTLMFGGHLWS
DLSPEQIPTADKLIAFTKDVFKAHLDADLDAEQGVDFKVRIQEKCIPQYTVGHRERMQAIKDAVSQKYDNRLTLTGMSFG
RGVGIGDNVLDSFWLAARQTEERKLLYPAFYLNQWLSLSYPSLLK

GO term prediction

Biological Process

GO:0006779 porphyrin-containing compound biosynthetic process
GO:0055114 oxidation-reduction process

Molecular Function

GO:0004729 oxygen-dependent protoporphyrinogen oxidase activity
GO:0016491 oxidoreductase activity

Cellular Component

None predicted.