Protein

MIA_03548_1

Length
360 amino acids


Browser: contig04:1514863-1515946+

Protein function

EGGNOG:0PFPKFDH1formate dehydrogenase
SGD closest match:S000005915FDH1Formate dehydrogenase 1
CGD closest match:CAL0000191596orf19.1117Formate dehydrogenase

Protein alignments

%idAln lengthE-value
MCA_06442_183.611%3600.0MCA_06442_1
A0A0J9XCB4_GEOCN76.731%3610.0Formate dehydrogenase OS=Geotrichum candidum GN=BN980_GECA09s01869g PE=3 SV=1
Q6CDN8_YARLI75.900%3610.0Formate dehydrogenase OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_B22506g PE=3 SV=1
UniRef50_Q6C00974.238%3610.0Formate dehydrogenase n=5 Tax=Saccharomycetales TaxID=4892 RepID=Q6C009_YARLI
A0A060T0V8_BLAAD73.056%3600.0Formate dehydrogenase OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C15906g PE=3 SV=1
A0A1E4TDG0_9ASCO71.271%3620.0Formate dehydrogenase OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_144271 PE=3 SV=1
FDH1_YEAST62.264%3711.13e-161Formate dehydrogenase 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=FDH1 PE=1 SV=1
A0A1D8PNS1_CANAL61.497%3749.59e-158Formate dehydrogenase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.1117 PE=3 SV=1
A0A167D133_9ASCO72.945%2921.80e-153Formate dehydrogenase (NAD+) OS=Sugiyamaella lignohabitans GN=FDH1 PE=3 SV=1
A0A1E3PJZ8_9ASCO32.794%2474.53e-28Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_69982 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0094

Protein family membership

Domains and repeats

1 50 100 150 200 250 300 360

Detailed signature matches

    1. cd05302 (FDH)
    2. MF_03210 (Formate_d...)
    1. PF00389 (2-Hacid_dh)
    1. SSF51735 (NAD(P)-bi...)
    1. PF02826 (2-Hacid_dh_C)
    1. PS00065 (D_2_HYDROX...)
    1. PS00671 (D_2_HYDROX...)
    2. PS00670 (D_2_HYDROX...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. SSF52283 (Formate/g...)

Residue annotation

  1. dimerization inter...
  2. NAD binding site c...
  3. catalytic site cd0...

Protein sequence

>MIA_03548_1
MVNILLVLYSGGSHAKDEPKLLGCTENELGLRKWLESQGHKLTTTDIKDGPQFESYLEDSEIVITTPFHPAYLTRERLLR
AKKLKLCVTAGVGSDHVDLDTANELKIGVLEVTGSNVTSVAEHAVMTMLVLVRNFVPSHDQVRQGQWDVAAVAKDEYDIE
GKVIATVGVGRIGTRILERLKPFNPKELLYYDYQPLSAEREKEIGCRRVGNLEEMLGQADIVTINTPLYDSTKGMFNKEL
ISKMKRGAWLINTARGAICVKEDVAAALKSGQLRGYGGDVWFPQPAPKDHPWRTMTNKYGAGNAMVPHMSGTSLDAQARY
AAGVKNILQSYLSGKYDYRPQDVIVINGHYGTKAYGNNKK

GO term prediction

Biological Process

GO:0008152 metabolic process
GO:0055114 oxidation-reduction process

Molecular Function

GO:0008863 formate dehydrogenase (NAD+) activity
GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0051287 NAD binding

Cellular Component

None predicted.