Protein

MIA_03532_1

Length
1,305 amino acids

Browser: contig04:1458034-1461952+

Protein function

EGGNOG:0PK3PPGUG_02967phosphatase
SGD closest match:S000005734PTP2Tyrosine-protein phosphatase 2
CGD closest match:CAL0000198260PTP3Tyrosine protein phosphatase

Protein alignments

%idAln lengthE-value
MCA_05763_142.308%5725.23e-116MCA_05763_1
A0A0J9XG21_GEOCN44.369%4444.19e-107Similar to Saccharomyces cerevisiae YER075C PTP3 Phosphotyrosine-specific protein phosphatase involved in the inactivation of mitogen-activated protein kinase (MAPK) during osmolarity sensing OS=Geotrichum candidum GN=BN980_GECA15s02237g PE=4 SV=1
UniRef50_A0A0J9XG2144.369%4448.58e-104Similar to Saccharomyces cerevisiae YER075C PTP3 Phosphotyrosine-specific protein phosphatase involved in the inactivation of mitogen-activated protein kinase (MAPK) during osmolarity sensing n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XG21_GEOCN
A0A161HK79_9ASCO42.947%3194.81e-70Tyrosine protein phosphatase PTP2 OS=Sugiyamaella lignohabitans GN=PTP2 PE=4 SV=1
A0A060T699_BLAAD38.854%3141.96e-59ARAD1C17886p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C17886g PE=4 SV=1
A0A1E3PPZ8_9ASCO36.420%3242.73e-51Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_49812 PE=4 SV=1
Q6C0H6_YARLI32.827%3291.64e-47YALI0F24585p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F24585g PE=4 SV=1
A0A1D8PU75_CANAL29.446%3433.26e-32Tyrosine protein phosphatase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=PTP3 PE=4 SV=1
A0A1E4TK41_9ASCO27.673%3182.24e-28Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_55782 PE=4 SV=1
PTP2_YEAST26.269%4534.07e-28Tyrosine-protein phosphatase 2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PTP2 PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0095

Protein family membership

None predicted.

Domains and repeats

  1. Domain
  2. Domain
1 200 400 600 800 1000 1200 1305

Detailed signature matches

  1. Domain IPR001763
    Rhodanese-like domain
    1. SSF52821 (Rhodanese...)
    2. SM00450 (rhod_4)
    3. PF00581 (Rhodanese)
    4. G3DSA:3.40.25...
    5. PS50206 (RHODANESE_3)
  2. Domain IPR029021
    Protein-tyrosine phosphatase-like
    1. SSF52799 ((Phosphot...)
    2. G3DSA:3.90.19...
  3. Domain IPR000387
    Tyrosine specific protein phosphatases domain
    1. PS50056 (TYR_PHOSPH...)
  4. Domain IPR000242
    PTP type protein phosphatase
    1. PR00700 (PRTYPHPHTASE)
    2. PS50055 (TYR_PHOSPH...)
    3. SM00194 (PTPc_3)
    4. PF00102 (Y_phosphatase)
  5. Domain IPR003595
    Protein-tyrosine phosphatase, catalytic
    1. SM00404 (ptp_7)
  6. SITE IPR016130
    Protein-tyrosine phosphatase, active site
    1. PS00383 (TYR_PHOSPH...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. cd00047 (PTPc)
  2. mobidb-lite (disord...)

Residue annotation

  1. active site cd00047

Protein sequence

>MIA_03532_1
MFSSIPPTSSPEKPPPAAKLDPGTENPPASQPASTASAHAPAYPPASTDTPLSIPSVNPQSQTIPPPKMSISIPPLQQQL
PPLASEPPPDSPSYFSHRAYPPPTTTVPPGSSVALAGPAPITTPSAYGHATSHYPPNNQPTSQIAPTTPTSVPAIPSVSS
VASSSYSFMNNPPLMTASLPLQGPPLAMVAAAAAAASSVTAASISSSVALTSIPSTSASNAPSKSSSALPSPAVARANTL
PVYSSNVHFDFPGQTPTIRTPGGTTATAHTSAALPYTNPQHYPSGSYIVPPVPASTSTTPNVPSPFIPPLSYHKFRSPSL
PANSLLDQNTDLSSSLNSLTYTDLQNMLNPDLSPSSSNTPSNNNKKTLIVDVRPYTQYSKSRIKSAINICIPSTLLKRST
FPLSRFGECMVPSQRTCIDNLGMYSSIVIYDQSTEKVSTTIYSPIVYTILKFSQSKSLKGKLYYLHGGISLVQEKYPDLI
EDNVIEFSDMAAQGQNQRTAPPNSLFLSSENNNNNPSNNNTSSANTTQTFNFPPVLTGFSLPLSSIKDGPIKPFASNING
GRENENFSDYDLSPLKLPADMSSTEINTYFPSWLRDIIQSDSGTQKIARRFNHIEEAQKARLQSAFSQGFKKPSDTSPRL
PTSSTSSSGSITQITDDVSTASIYNNNKVTSINTPIESIAPKNFISSSSSTQINPQHVHLNYPVTKVDSLLVHNDSNNQT
HISETTDDCCEPVTPDELQVRYSFSAGVELGAKNRYTNIWPYDHTRVRLPEVLPEDEKSYSDNDVSDTITKDASDENLSN
SNEYSSLQNQSLQPNPVPKIRGLSPAIEDNSTSDVASSNNGSDYFNASYISPHGSLNRYIATQGPLPDTFNDFWNVVWDK
KIPLIIMLTAEVEGGQIKCHRYWEDGIYGSSTPIDGASGTGHQLKLTLISTHEQKLSKNTGNSVIVRRFRLINKGPVSTD
PAGTPRSHTIVQLQYTSWPDLGSPATPEDLIELCSLKDRYLKELVGQNSTSIGASLSPPQNISKNKSPLPWVLVHCSAGC
GRTGTFCTVDSVIDILREYGMSSLPKRQIRLTRQTSGGSTSLQVSSAISQSSDGPDSGSLGESSSPQPLATKQVDFESYD
LVYRTVHDFRRQRLSMVQVLRQYVLCYETVIMWIHQQYLRENGNPALSLSPNSATSLTDDKVPKTAIGTTCTSSDSITGN
DLLSPTIKTRRHYSTPAVVLSPIAKDAQTRNIVNGTTNRVMSPVIVNGNGGTPPAAISYAGGSRSSSVGSLLPTTPVRES
LLVNTHKQQHHPIVDGSNGSHVHLK

GO term prediction

Biological Process

GO:0006470 protein dephosphorylation
GO:0016311 dephosphorylation

Molecular Function

GO:0004725 protein tyrosine phosphatase activity
GO:0016791 phosphatase activity

Cellular Component

None predicted.