Protein
MIA_03526_1
Length
831 amino acids
Browser: contig04:1440445-1443041+
Protein function
EGGNOG: | 0PGH5 | FG05174.1 | Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) |
---|---|---|---|
SGD closest match: | S000000872 | RNR1 | Ribonucleoside-diphosphate reductase large chain 1 |
CGD closest match: | CAL0000199428 | RNR1 | Ribonucleoside-diphosphate reductase |
Protein alignments
%id | Aln length | E-value | ||
---|---|---|---|---|
MCA_01279_1 | 73.087% | 758 | 0.0 | MCA_01279_1 |
Q5A0N3_CANAL | 65.866% | 791 | 0.0 | Ribonucleoside-diphosphate reductase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=RNR1 PE=3 SV=1 |
A0A0J9XFZ3_GEOCN | 67.405% | 767 | 0.0 | Ribonucleoside-diphosphate reductase OS=Geotrichum candidum GN=BN980_GECA14s01319g PE=3 SV=1 |
UniRef50_A0A1B7SMA0 | 65.262% | 783 | 0.0 | Ribonucleoside-diphosphate reductase n=61 Tax=cellular organisms TaxID=131567 RepID=A0A1B7SMA0_9ASCO |
Q6BZQ3_YARLI | 64.020% | 806 | 0.0 | Ribonucleoside-diphosphate reductase OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F31735g PE=3 SV=1 |
A0A1E4TDZ6_9ASCO | 63.975% | 805 | 0.0 | Ribonucleoside-diphosphate reductase OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_26775 PE=3 SV=1 |
A0A1E3PIT4_9ASCO | 65.354% | 762 | 0.0 | Ribonucleoside-diphosphate reductase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_51452 PE=3 SV=1 |
A0A060T162_BLAAD | 62.142% | 803 | 0.0 | Ribonucleoside-diphosphate reductase OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C21780g PE=3 SV=1 |
RIR1_YEAST | 63.671% | 779 | 0.0 | Ribonucleoside-diphosphate reductase large chain 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=RNR1 PE=1 SV=2 |
A0A167FQX0_9ASCO | 65.390% | 705 | 0.0 | Ribonucleoside-diphosphate reductase OS=Sugiyamaella lignohabitans GN=RNR1 PE=3 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.0449
Protein family membership
None predicted.
Domains and repeats
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Domain
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Domain
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Domain
1
100
200
300
400
500
600
700
831
Detailed signature matches
no IPR
Unintegrated signatures
Residue annotation
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active site cd01679
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dimer interface cd...
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catalytic residues...
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effector binding s...
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R2 peptide binding...
Protein sequence
>MIA_03526_1 MFVIKRDGHKERVQFDKITARISRLSAGLAPHNVDPARVAQIVIHGIYEGVSTVDLDNLAAEAAASLTTLHSDYGVLAGR IIVSNLHKQTQERFSEVVKALYHHYNPRAKELSPVVSKELYDTVMEHAAELDAAIDSDRDYDLTYFGVRTLERSYLLRIN NKVSERPQHLLMRTALGIHGNEISRVLESYNLMSRRFFTHASPTLFNAGTVRPQMSSCFLVAMKEDSMHGIYNTLTTCAL ISKYAGGIGLHVHNIRSKGSYISGTNGISTGVVPMLKVFNATARYADQGGSKRPGAFAIYLEPWHGDILKFLEIRKNHGA EEMRARDLFTALWIPDYFMKKVEMGETWCLFSPSDAPRLADTYGKEFEELYDKYEAENRYQEKISAQVLWKAIVDAQIET GSPFILFKDACNSKSNQSNLGTIKSSNLCTEIIQYSSPDEVAVCNLASLALPMFIDYNETSAWFDFLALHRVTKVVLRNL DTIIDKNWYPVPEAEKSNKRHRPVAVGIQGLADTLLALRLPYESDETKRLNANIFETIYHAALEASVELAKEHGPYETFK GSPASEGFLQYDLWDHKPSGLWDWEKLKVDIKKHGLRNSLVTALMPTASTSQILGFNECFEPYTSNIYVRRVLAGEFQIV NPWLLKDLTKLGLWNEEMKTAILRDRGSIQNIPCIPSELKRLYKTVWEIPQKEVINLAVGRAPFIDQSQSMNLYLKEPTL AKISSMHFYSWKQGLKTGMYYLRSRAAADPIQFTVAGESAETQNIFRNIKTPSLDLLEMKQYLEIDHTKGRPRESQIVTV DSKTGLVDVLRPRGDMLGIPGFSREEPRRRV
GO term prediction
Biological Process
GO:0006260 DNA replication
GO:0055114 oxidation-reduction process
Molecular Function
GO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor
GO:0005524 ATP binding
Cellular Component
None predicted.