Protein

MIA_03490_1

Length
749 amino acids

Browser: contig04:1339321-1341571+

Protein function

EGGNOG:0PI3BFG07958.1ubiquitin carboxyl-terminal hydrolase
SGD closest match:S000004836UBP8Ubiquitin carboxyl-terminal hydrolase 8
CGD closest match:CAL0000200116orf19.1767Ubiquitinyl hydrolase 1

Protein alignments

%idAln lengthE-value
A0A0J9X501_GEOCN42.371%7340.0Ubiquitinyl hydrolase 1 OS=Geotrichum candidum GN=BN980_GECA02s07457g PE=3 SV=1
UniRef50_A0A0J9X50142.371%7340.0Ubiquitinyl hydrolase 1 n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9X501_GEOCN
MCA_01383_145.683%6376.60e-168MCA_01383_1
A0A060T4A7_BLAAD39.640%4441.58e-101Ubiquitinyl hydrolase 1 OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C43340g PE=3 SV=1
Q6CCH1_YARLI38.009%4421.84e-91YALI0C09438p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_C09438g PE=3 SV=1
A0A1E3PMY4_9ASCO42.075%3473.34e-88Ubiquitinyl hydrolase 1 OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_82517 PE=3 SV=1
A0A161HH72_9ASCO33.333%5371.10e-78Ubiquitinyl hydrolase 1 OS=Sugiyamaella lignohabitans GN=UBP8 PE=3 SV=1
A0A1D8PIP6_CANAL33.485%4391.74e-67Ubiquitinyl hydrolase 1 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.1767 PE=3 SV=1
A0A1E4TK86_9ASCO39.809%3147.86e-61Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_758 PE=3 SV=1
UBP8_YEAST29.787%4701.33e-58Ubiquitin carboxyl-terminal hydrolase 8 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=UBP8 PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.4530
Predicted cleavage: 13

Protein family membership

None predicted.

Domains and repeats

  1. Domain
  2. Domain
1 100 200 300 400 500 600 749

Detailed signature matches

  1. Domain IPR013083
    Zinc finger, RING/FYVE/PHD-type
    1. G3DSA:3.30.40.10
  2. Domain IPR001607
    Zinc finger, UBP-type
    1. PS50271 (ZF_UBP)
    2. PF02148 (zf-UBP)
  3. Domain IPR028889
    Ubiquitin specific protease domain
    1. PS50235 (USP_3)
  4. Domain IPR001394
    Peptidase C19, ubiquitin carboxyl-terminal hydrolase
    1. PF00443 (UCH)
  5. SITE IPR018200
    Ubiquitin specific protease, conserved site
    1. PS00972 (USP_1)
    2. PS00973 (USP_2)
Unintegrated signatures no IPR
Unintegrated signatures
  1. Coil
  2. G3DSA:3.90.70.10
  3. PS51257 (PROKAR_LIP...)
  4. SSF54001 (Cysteine ...)
  5. SSF57850 (RING/U-box)
  6. mobidb-lite (disord...)

Protein sequence

>MIA_03490_1
MAPTKAQIATRTPASQITGVGAPLATGYATYGCTHTRSALHENAARPRILRAYELAVRLCLARAHASVSSGATASSAGSA
ARVNGTKRKAGDGGGPMKKTKVKKGAARAAAETPAGGAWEETTEEGRIGRRALGLKCGECGAAGPAILCCLQCAFIGCAT
HGAKHASRASHPLFVDLVAGGEGMLFCAGCGDYVFDATFEAVRVEKIRQHLERGVRRLPGGSVLRHGPLSLARGPGLRTG
KVLGQEEDSFGVVDDEDEDEDEDEDEEGESTFKNETTKEDQLISKEKERRRAVRYLKELGPGYSIVQNKALLPAYQATSA
LRGFYNMGSTCFMSVIFQALVHNPLVRNFYLSGGHERGLRCGRHVKGHGADDKAGEGEGHVVGSAGGVGPGEGGYEEEGK
AGSGGSIGGNKAVIDPNVSMNCLSCSLDEVFTEFFTSSSVAGFGPTELLTTAWQIKRSLGGNTQQDAHEFLQVVLNELHG
SHYDSAVFARGTRGALRDIGLPRAAEVPGVLRSVEDVQIQRCGCVAHRTFCGELESRIVCQECGTVSSTVVDPIMDLSLD
VGRAGSAGGPVDGEGSKRKNGDGSRAGTPGDGGPAASTTLEECLDRFTSGERLDATFTCSGAACGGARRQIEKTLRLRRV
PAVLAIQLKRFSHTGASAKIDTHVRFPLVLDMARYTVGGGQGRLLYELFGVVCHQGSLNTGHYTCMMKTSSGRWFHFDDA
MVTTIGISQVLEKKAYLLFYIVQEVPSIV

GO term prediction

Biological Process

GO:0006511 ubiquitin-dependent protein catabolic process
GO:0016579 protein deubiquitination

Molecular Function

GO:0008270 zinc ion binding
GO:0036459 thiol-dependent ubiquitinyl hydrolase activity

Cellular Component

None predicted.