Protein

MCA_01383_1

Length
874 amino acids

Browser: contigA:4317962-4320587-

RNA-seq: read pairs 372, FPKM 5.3, percentile rank 17.9% (100% = highest expression)

Protein function

EGGNOG:0PI3BFG07958.1ubiquitin carboxyl-terminal hydrolase
SGD closest match:S000004836UBP8Ubiquitin carboxyl-terminal hydrolase 8
CGD closest match:CAL0000200116orf19.1767Ubiquitinyl hydrolase 1

Protein alignments

%idAln lengthE-value
A0A0J9X501_GEOCN39.41%8459e-176Ubiquitinyl hydrolase 1 OS=Geotrichum candidum GN=BN980_GECA02s07457g PE=3 SV=1
UniRef50_A0A0J9X50139.41%8452e-172Ubiquitinyl hydrolase 1 n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9X501_GEOCN
MIA_03490_145.38%6394e-168MIA_03490_1
Q6CCH1_YARLI33.45%2871e-40YALI0C09438p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_C09438g PE=3 SV=1
A0A1E3PMY4_9ASCO42.31%1822e-37Ubiquitinyl hydrolase 1 OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_82517 PE=3 SV=1
A0A161HH72_9ASCO38.39%2111e-34Ubiquitinyl hydrolase 1 OS=Sugiyamaella lignohabitans GN=UBP8 PE=3 SV=1
A0A060T4A7_BLAAD38.95%1901e-33Ubiquitinyl hydrolase 1 OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C43340g PE=3 SV=1
A0A1E4TK86_9ASCO38.51%1613e-27Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_758 PE=3 SV=1
UBP8_YEAST35.68%1855e-28Ubiquitin carboxyl-terminal hydrolase 8 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=UBP8 PE=1 SV=1
A0A1D8PIP6_CANAL37.27%1613e-25Ubiquitinyl hydrolase 1 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.1767 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.8007
Predicted cleavage: 47

Protein family membership

None predicted.

Domains and repeats

  1. Domain
  2. Domain
1 100 200 300 400 500 600 700 800 874

Detailed signature matches

  1. Domain IPR013083
    Zinc finger, RING/FYVE/PHD-type
    1. G3DSA:3.30.40.10
  2. Domain IPR001607
    Zinc finger, UBP-type
    1. PS50271 (ZF_UBP)
    2. PF02148 (zf-UBP)
  3. Domain IPR028889
    Ubiquitin specific protease domain
    1. PS50235 (USP_3)
  4. Domain IPR001394
    Peptidase C19, ubiquitin carboxyl-terminal hydrolase
    1. PF00443 (UCH)
  5. SITE IPR018200
    Ubiquitin specific protease, conserved site
    1. PS00972 (USP_1)
    2. PS00973 (USP_2)
Unintegrated signatures no IPR
Unintegrated signatures
  1. Coil
  2. G3DSA:3.90.70.10
  3. SSF54001 (Cysteine ...)
  4. SSF57850 (RING/U-box)
  5. mobidb-lite (disord...)

Protein sequence

>MCA_01383_1
MAPTKAQIATRTPQSQIIGVGKTISLSFKHYGCQHIRSILSSNTQNREKILRAYELAVRISLARSEKVYQPYSQSRNKRK
NKTATDIKINKKKNRGKNNNNSSSTIFQDEYYSTDDDNESYKETFQKAQKINTKLQTLKCRDCGAFDPALYCCLHCSFVG
CLDHLKFHHTNFDSKDNHVLAVDLVLGSEGVLYCTGCNEYVYDATFEEIKIEKIRQHVSLGLEGLPQGSVVQSGSLQLGT
ITRYNTPSSESLEEEEKTLIDEQVNGDSNSTEFQIDTYMKETGPGYSIVREKALLPAYQATSALRGFYNMGSTCFMSVIF
QALLHNPLVRNFYLAGGHERGVNCGRNTNGSTTNDGSTEASTIDLTSNDKGQFLDVKNNGISSSFSSSANTPNYTSNDEK
SPQPMSDKPGQGKVILESNASINCLSCSLDEVFTEFFTSSSVAGFGPTELLTTAWQVKRSLGGSSQQDAHEFLQIILNEL
HSNHYDSPVFLKGCQTAFRDIGMTTDQQTATNSKSIPRSFRNLEEVNIQNCGCVSHRTFCGELESVLSCQGCGRVSSIVV
DPMMDLSLDVRETGVKRRNKNVQQSNLNSGANTPSASSTNVAGSISSSTTGLFNNTGKRKAVSGKNLPGTYSNGSSRYSS
PSIMQDMTMSPLDSFANSTNANGTDSPSSFPPSSSSSTSSQDTLTEDRIPVTLEECLDRFTQGETLHDATSFCETCQKQQ
PIAKKMSIKRLPSVLTIQLKRFSHTSSKIESHVDFPLVLDMNKYTSCYFKEMENSQQEEEDAAEETESEEYMHDQQQHQI
PQTIQNGEVLYDLFGVVCHHGTLNTGHYTCMMKTSSGRWFHFDDAVVTTISANKVKQKNAYLLFYIVKQVPSVV

GO term prediction

Biological Process

GO:0006511 ubiquitin-dependent protein catabolic process
GO:0016579 protein deubiquitination

Molecular Function

GO:0008270 zinc ion binding
GO:0036459 thiol-dependent ubiquitinyl hydrolase activity

Cellular Component

None predicted.