MIA_03478_1

Protein

Length

308 amino acids

Protein function

EGGNOG:	0PKFE	FG08511.1	d-arabinitol
SGD closest match:	S000005146	SPS19	Peroxisomal 2,4-dienoyl-CoA reductase SPS19
CGD closest match:	CAL0000174204	ARD	Ardp

Protein alignments

	%id	Aln length	E-value
A0A167BXQ3_9ASCO	48.684%	304	3.22e-87	Sps19p OS=Sugiyamaella lignohabitans GN=SPS19 PE=4 SV=1
A0A060T1S4_BLAAD	44.951%	307	1.08e-76	ARAD1C18392p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C18392g PE=4 SV=1
A0A0J9XIE3_GEOCN	38.857%	350	8.44e-72	Uncharacterized protein OS=Geotrichum candidum GN=BN980_GECA18s02144g PE=4 SV=1
UniRef50_A0A0J9XE82	39.688%	320	4.71e-67	Uncharacterized protein n=2 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XE82_GEOCN
Q6C367_YARLI	45.992%	237	5.28e-69	YALI0F02211p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F02211g PE=3 SV=1
A0A1E3PQI7_9ASCO	44.156%	231	4.14e-66	NAD(P)-binding protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_50100 PE=4 SV=1
MCA_05402_1	59.355%	155	1.70e-55	MCA_05402_1
A0A1D8PPB1_CANAL	39.159%	309	1.79e-52	Ardp OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=ARD PE=4 SV=1
A0A1E4TBX3_9ASCO	45.026%	191	1.54e-51	Uncharacterized protein (Fragment) OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_29448 PE=4 SV=1
SPS19_YEAST	28.824%	170	2.38e-10	Peroxisomal 2,4-dienoyl-CoA reductase SPS19 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SPS19 PE=1 SV=4

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.9408
Predicted cleavage: 34

Protein family membership

Short-chain dehydrogenase/reductase SDR (IPR002347)

Domains and repeats

Domain
10 - 307
NAD(P)-binding domain (IPR016040)

1 50 100 150 200 250 308

Detailed signature matches

IPR002347

Short-chain dehydrogenase/reductase SDR
1. PR00081 (GDHRDH)
  
  194 - 213
  
  PRINTS
  PR00081 (GDHRDH)
  
  166 - 182
  
  PRINTS
  PR00081 (GDHRDH)
  
  215 - 232
  
  PRINTS
  PR00081 (GDHRDH)
  
  16 - 33
  
  PRINTS
  PR00081 (GDHRDH)
  
  269 - 289
  
  PRINTS
  PR00081 (GDHRDH)
2. PF00106 (adh_short)
  
  15 - 237
  
  Pfam
  PF00106 (adh_short)
IPR016040

NAD(P)-binding domain
1. SSF51735 (NAD(P)-bi...)
  
  10 - 307
  
  SUPERFAMILY
  SSF51735 (NAD(P)-binding Rossmann-fold domains)
IPR020904

Short-chain dehydrogenase/reductase, conserved site
1. PS00061 (ADH_SHORT)
  
  181 - 209
  
  PROSITE patterns
  PS00061 (ADH_SHORT)

no IPR

Unintegrated signatures

Coil

236 - 256

COILS
Coil (Coil)
G3DSA:3.40.50...

4 - 308

GENE3D
G3DSA:3.40.50.720 (G3DSA:3.40.50.720)
NON_CYTOPLASM... (N...)

33 - 308

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)
PF13561 (adh_short_C2)

252 - 306

Pfam
PF13561 (adh_short_C2)
SIGNAL_PEPTIDE (Sig...)

1 - 32

PHOBIUS
SIGNAL_PEPTIDE (Signal Peptide)
SIGNAL_PEPTID... (S...)

28 - 32

PHOBIUS
SIGNAL_PEPTIDE_C_REGION (Signal peptide C-region)
SIGNAL_PEPTID... (S...)

16 - 27

PHOBIUS
SIGNAL_PEPTIDE_H_REGION (Signal peptide H-region)
SIGNAL_PEPTID... (S...)

1 - 15

PHOBIUS
SIGNAL_PEPTIDE_N_REGION (Signal peptide N-region)

Protein sequence

>MIA_03478_1
MLFSGIKNPFSLSNKLIILIGATGGLGNAVSRAVVNSGASRVILVDNGPEAKPKLEVLEKELKEVYTKMINFREFKISSF
QCDITKGSKVKALMEEIFYEDKKHLAKTKTDFTSCSLINMAGVCENLSAIDYPQENIKRIIDINLLGSMLVSREFARQVI
KSNCHNIIYHQASIVLTASMSGSIINYPQPQAPYNMTKAGVIHLSKSLASEWVDDRIRVNSLSPGYILTPMTKKILERDE
REKAKLRENNEKSVSKTVSLSEEWKKRTPMGRLADPEELAWPMVFLASDASSFMTGSDLIVDGGYTIR

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0016491 oxidoreductase activity

Cellular Component