MIA_03471_1

Protein

Length

1,672 amino acids

Browser: contig04:1286917-1291964-

Protein function

EGGNOG:	0PKA3		reverse transcriptase
SGD closest match:	S000007261	AI1	Putative COX1/OXI3 intron 1 protein
CGD closest match:	CAL0000176110	orf19.7274	Uncharacterized protein

Protein alignments

	%id	Aln length	E-value
MCA_03180_1	39.924%	1057	0.0	MCA_03180_1
UniRef50_A0A167E5I2	35.761%	1071	0.0	Polyprotein of L1-like non-LTR retrotransposon Zorro 3 n=7 Tax=Sugiyamaella lignohabitans TaxID=796027 RepID=A0A167E5I2_9ASCO
A0A167EY19_9ASCO	35.278%	1063	0.0	Polyprotein of L1-like non-LTR retrotransposon Zorro 3 OS=Sugiyamaella lignohabitans GN=POL92 PE=4 SV=1
A0A0J9XC44_GEOCN	28.571%	252	5.47e-21	Uncharacterized protein (Fragment) OS=Geotrichum candidum GN=BN980_GECA08s04349g PE=4 SV=1
A0A1D8PFY7_CANAL	25.556%	270	2.12e-13	Uncharacterized protein OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.7274 PE=4 SV=1
A0A060T0U2_BLAAD	52.000%	50	8.69e-09	ARAD1C18194p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C18194g PE=4 SV=1
AI1M_YEAST	24.503%	151	4.84e-06	Putative COX1/OXI3 intron 1 protein OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=AI1 PE=4 SV=2

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0413

Protein family membership

None predicted.

Domains and repeats

Domain
587 - 823
Endonuclease/exonuclease/phosphatase (IPR005135)
1,080 - 1,350
Reverse transcriptase domain (IPR000477)

1 200 400 600 800 1000 1200 1400 1672

Detailed signature matches

IPR005135

Endonuclease/exonuclease/phosphatase
1. SSF56219 (DNase I-like)
  
  605 - 820
  
  SUPERFAMILY
  SSF56219 (DNase I-like)
2. G3DSA:3.60.10.10
  
  587 - 823
  
  GENE3D
  G3DSA:3.60.10.10 (G3DSA:3.60.10.10)
3. PF14529 (Exo_endo_p...)
  
  700 - 815
  
  Pfam
  PF14529 (Exo_endo_phos_2)
IPR000477

Reverse transcriptase domain
1. PF00078 (RVT_1)
  
  1,102 - 1,349
  
  Pfam
  PF00078 (RVT_1)
2. PS50878 (RT_POL)
  
  1,080 - 1,350
  
  PROSITE profiles
  PS50878 (RT_POL)

no IPR

Unintegrated signatures

Coil

180 - 221

COILS
Coil (Coil)

868 - 888

COILS
Coil (Coil)

904 - 924

COILS
Coil (Coil)

300 - 320

COILS
Coil (Coil)
G3DSA:1.20.5.170

156 - 273

GENE3D
G3DSA:1.20.5.170 (G3DSA:1.20.5.170)

274 - 395

GENE3D
G3DSA:1.20.5.170 (G3DSA:1.20.5.170)
G3DSA:3.30.70...

1,150 - 1,350

GENE3D
G3DSA:3.30.70.270 (G3DSA:3.30.70.270)
SSF56672 (DNA/RNA p...)

1,042 - 1,293

SUPERFAMILY
SSF56672 (DNA/RNA polymerases)
cd01650 (RT_nLTR_like)

1,093 - 1,350

CDD
cd01650 (RT_nLTR_like)
mobidb-lite (disord...)

1 - 29

MobiDB Lite
mobidb-lite (disorder_prediction)

98 - 141

MobiDB Lite
mobidb-lite (disorder_prediction)

55 - 78

MobiDB Lite
mobidb-lite (disorder_prediction)

Residue annotation

putative NTP bindi...

1,179D

putative NTP binding site
1,179D, 1,180I, 1,181Q, 1,182G, 1,183A, 1,184F, 1,238Q, 1,270D
CDD
cd01650 (RT_nLTR_like)

1,180I

putative NTP binding site
1,179D, 1,180I, 1,181Q, 1,182G, 1,183A, 1,184F, 1,238Q, 1,270D
CDD
cd01650 (RT_nLTR_like)

1,181Q

putative NTP binding site
1,179D, 1,180I, 1,181Q, 1,182G, 1,183A, 1,184F, 1,238Q, 1,270D
CDD
cd01650 (RT_nLTR_like)

1,182G

putative NTP binding site
1,179D, 1,180I, 1,181Q, 1,182G, 1,183A, 1,184F, 1,238Q, 1,270D
CDD
cd01650 (RT_nLTR_like)

1,183A

putative NTP binding site
1,179D, 1,180I, 1,181Q, 1,182G, 1,183A, 1,184F, 1,238Q, 1,270D
CDD
cd01650 (RT_nLTR_like)

1,184F

putative NTP binding site
1,179D, 1,180I, 1,181Q, 1,182G, 1,183A, 1,184F, 1,238Q, 1,270D
CDD
cd01650 (RT_nLTR_like)

1,238Q

putative NTP binding site
1,179D, 1,180I, 1,181Q, 1,182G, 1,183A, 1,184F, 1,238Q, 1,270D
CDD
cd01650 (RT_nLTR_like)

1,270D

putative NTP binding site
1,179D, 1,180I, 1,181Q, 1,182G, 1,183A, 1,184F, 1,238Q, 1,270D
CDD
cd01650 (RT_nLTR_like)
putative active si...

1,179D

putative active site
1,179D, 1,180I, 1,181Q, 1,182G, 1,183A, 1,184F, 1,238Q, 1,239G, 1,268F, 1,270D, 1,271D, 1,346L, 1,347G
CDD
cd01650 (RT_nLTR_like)

1,180I

putative active site
1,179D, 1,180I, 1,181Q, 1,182G, 1,183A, 1,184F, 1,238Q, 1,239G, 1,268F, 1,270D, 1,271D, 1,346L, 1,347G
CDD
cd01650 (RT_nLTR_like)

1,181Q

putative active site
1,179D, 1,180I, 1,181Q, 1,182G, 1,183A, 1,184F, 1,238Q, 1,239G, 1,268F, 1,270D, 1,271D, 1,346L, 1,347G
CDD
cd01650 (RT_nLTR_like)

1,182G

putative active site
1,179D, 1,180I, 1,181Q, 1,182G, 1,183A, 1,184F, 1,238Q, 1,239G, 1,268F, 1,270D, 1,271D, 1,346L, 1,347G
CDD
cd01650 (RT_nLTR_like)

1,183A

putative active site
1,179D, 1,180I, 1,181Q, 1,182G, 1,183A, 1,184F, 1,238Q, 1,239G, 1,268F, 1,270D, 1,271D, 1,346L, 1,347G
CDD
cd01650 (RT_nLTR_like)

1,184F

putative active site
1,179D, 1,180I, 1,181Q, 1,182G, 1,183A, 1,184F, 1,238Q, 1,239G, 1,268F, 1,270D, 1,271D, 1,346L, 1,347G
CDD
cd01650 (RT_nLTR_like)

1,238Q

putative active site
1,179D, 1,180I, 1,181Q, 1,182G, 1,183A, 1,184F, 1,238Q, 1,239G, 1,268F, 1,270D, 1,271D, 1,346L, 1,347G
CDD
cd01650 (RT_nLTR_like)

1,239G

putative active site
1,179D, 1,180I, 1,181Q, 1,182G, 1,183A, 1,184F, 1,238Q, 1,239G, 1,268F, 1,270D, 1,271D, 1,346L, 1,347G
CDD
cd01650 (RT_nLTR_like)

1,268F

putative active site
1,179D, 1,180I, 1,181Q, 1,182G, 1,183A, 1,184F, 1,238Q, 1,239G, 1,268F, 1,270D, 1,271D, 1,346L, 1,347G
CDD
cd01650 (RT_nLTR_like)

1,270D

putative active site
1,179D, 1,180I, 1,181Q, 1,182G, 1,183A, 1,184F, 1,238Q, 1,239G, 1,268F, 1,270D, 1,271D, 1,346L, 1,347G
CDD
cd01650 (RT_nLTR_like)

1,271D

putative active site
1,179D, 1,180I, 1,181Q, 1,182G, 1,183A, 1,184F, 1,238Q, 1,239G, 1,268F, 1,270D, 1,271D, 1,346L, 1,347G
CDD
cd01650 (RT_nLTR_like)

1,346L

putative active site
1,179D, 1,180I, 1,181Q, 1,182G, 1,183A, 1,184F, 1,238Q, 1,239G, 1,268F, 1,270D, 1,271D, 1,346L, 1,347G
CDD
cd01650 (RT_nLTR_like)

1,347G

putative active site
1,179D, 1,180I, 1,181Q, 1,182G, 1,183A, 1,184F, 1,238Q, 1,239G, 1,268F, 1,270D, 1,271D, 1,346L, 1,347G
CDD
cd01650 (RT_nLTR_like)
putative nucleic a...

1,239G

putative nucleic acid binding site
1,239G
CDD
cd01650 (RT_nLTR_like)

Protein sequence

>MIA_03471_1
MEKMPDPPDKNNPTTPSGNDPRADINNLDNHVEQTKINDIEKTIAVGLKQKGVSHLKGHHSHDVHHVKASPKIHKDDDKI
DKIANLDKLQKKLDHLNKHPDHEHQENDPDSQMLDTTSDPDSPTENFSSGGDTEIDANNSRDIDINMADNITITPTHEIE
SVNCISETLVAKVNSLAEILVEVNNKYDNMGKNCQSLKKENELLKKESEILTAENAVLRNKFAEFSLKFDQFEGSWNTLR
SEVDNLKSKEVHGEVKKITIEQIKKDVKANHDHCVRNSQKAEELANLAITDWTQRAAENKQTVKKEINHVKEITQNLEKR
IDGIEYQVGTISTKTDLASKEITYAKQEIKSAVRKVDTLPYKLTTRPSNSNPIKLKDIMKAQKQQREEQVANAKPIFRVC
IRIPATANNIRRETIGAKIDSIAQKNVAEMVEFTTKGNLYVNINDKEFADRAAEWIPQIDPTFSLLDTEPWYKAKLLGVP
EEATIQEVKDALYTFGEYHIVLNNEPKVIYKNHDFQTILVCFRNVSDFAKCADKLVIRYTKIKVTPYVNRPKTPEQLRRI
QMKNKKTKRLQMRNPQKNLWMTQKLKNSWNLLQKKPQLLRIPLMIYKVFQLNCHKSKSITETILDEKEPDILLLQEPYFS
KYGPINHKEWIPIYAIAQNGNTPCRAITYIRSNSDLRAVTTKIEKLTNTDMVTIMVKDFTLVNVYNQPKPSKKFPEPPAL
EILKKEVQGQYDKLIIAGDYNLHHREWETESNPDADTNEIVDWLHENDMMLITPPNRKTYRNKTTIDLVYCSVNLLHRII
FRKIDENSLSDHAIVEWDLSFFQHQHEEEKLTSIERLNIQQANWDKFEQELSNAIKTLNVHDKALKSLDQIDSQAEILEN
VIKKAMASSMEKIKLVRKSKRYWNAELRKKLEFALKAKREARLRQPTFALKKQKIQEAKEATRDFDRSLREASSEQWNKF
LSGLEENDIWRVLRYINPKGNDTIIPQIRKEDGTLTTTVEEKRHEIWKALLPEIDHGPDKHFEIDDDSRWPKLDIKEVEI
ALANTPNDKAAGDDGITGLVLKKAWKNKDYQIRFFKLLQACVNFGYHPKVWRHGIIVVIPKPKKPDYSKPRAYRPISLLK
IPSKVLEKIMQTRMTKLTDKLLPPEQYGGRKGYCATDAVLELVQRIETSREKISAILIDIQGAFDNVNRNILAETMENMG
LPNALISWTYQFISQREASMLMDRRKGPVQKISTGIPQGSPISPLLFLIYSTPMYKAIQQWGGKAFGFIDDVTITVEGTI
DKNTELLSNILAKCCEWAKSRMTKIDLGDKLGFIHFAKNIKANDQKAQLTLPNGEHLKPQKEVKLLGIILDNTLDFKSHI
MSKITKARKAIGAIWRLGGTLRGMRGSSVRSLYIACVRPIIEYGMEIWFHKILKGEIHKLGVAQNMALRRVVGAYRTTPI
AVLQKEAGVMPYNIRLNFMIARKAIRLHLNISNTNPIKEHLLTLIENSPIAKLTSVYLEAEEDRKVVIKNLMKTRKKPVF
GPVTRELLQSQLIAILKKQAIEKWRDAYWHSKKDQWYHDITAETPCSDNLSKMTTGVVMKKDSRRTLSFITQFRTGHGNF
GAWFKKFGIQKDSYDCECGELETVRHILVECPLLEEKRKGLRRISPEMDMSTLLNRLTGLQEIARFISVWRE

GO term prediction

Biological Process

None predicted.

Molecular Function

None predicted.

Cellular Component

None predicted.

Filter view on

Entry type

Status

Per-residue features

MIA_03471_1

Protein function

Protein alignments

Mitochondrial localization by mitoprotII

Protein family membership

Domains and repeats

Detailed signature matches

Residue annotation

Protein sequence

GO term prediction

Biological Process

Molecular Function

Cellular Component