MIA_03434_1

Protein

Length

1,362 amino acids

Browser: contig04:1190499-1194651+

Protein function

EGGNOG:	0PGP3	STE20	serine threonine-protein kinase
SGD closest match:	S000000999	STE20	Serine/threonine-protein kinase STE20
CGD closest match:	CAL0000198103	CST20	Serine/threonine-protein kinase CST20

Protein alignments

	%id	Aln length	E-value
MCA_04397_1	80.702%	285	2.32e-158	MCA_04397_1
A0A0J9X7V4_GEOCN	80.623%	289	9.05e-161	Similar to Saccharomyces cerevisiae YHL007C STE20 Cdc42p-activated signal transducing kinase of the PAK (P21-activated kinase) family OS=Geotrichum candidum GN=BN980_GECA04s06214g PE=4 SV=1
UniRef50_A0A0J9X7V4	80.623%	289	1.85e-157	Similar to Saccharomyces cerevisiae YHL007C STE20 Cdc42p-activated signal transducing kinase of the PAK (P21-activated kinase) family n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9X7V4_GEOCN
A0A167DPV5_9ASCO	74.048%	289	1.43e-149	Mitogen-activated protein kinase kinase kinase kinase STE20 OS=Sugiyamaella lignohabitans GN=STE20 PE=4 SV=1
STE20_YARLI	75.087%	289	3.00e-147	Serine/threonine-protein kinase STE20 OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=STE20 PE=3 SV=1
A0A060T898_BLAAD	73.356%	289	5.07e-148	ARAD1C35046p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C35046g PE=4 SV=1
STE20_YEAST	71.329%	286	6.33e-137	Serine/threonine-protein kinase STE20 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=STE20 PE=1 SV=1
STE20_CANAL	70.629%	286	3.63e-134	Serine/threonine-protein kinase CST20 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=CST20 PE=3 SV=1
A0A1E4TI70_9ASCO	68.966%	290	6.53e-141	Uncharacterized protein (Fragment) OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_18692 PE=4 SV=1
A0A1E3PGH3_9ASCO	67.333%	300	7.35e-136	Pkinase-domain-containing protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_26587 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.1221
Predicted cleavage: 21

Protein family membership

None predicted.

Domains and repeats

Domain
489 - 564
CRIB domain (IPR000095)
p21 activated kinase binding domain (IPR033923)
1,067 - 1,329
Protein kinase-like domain (IPR011009)
Protein kinase domain (IPR000719)

1 200 400 600 800 1000 1200 1362

Detailed signature matches

IPR000095

CRIB domain
1. G3DSA:3.90.81...
  
  489 - 564
  
  GENE3D
  G3DSA:3.90.810.10 (G3DSA:3.90.810.10)
2. PF00786 (PBD)
  
  491 - 547
  
  Pfam
  PF00786 (PBD)
3. SM00285 (PBD_5)
  
  492 - 527
  
  SMART
  SM00285 (PBD_5)
IPR033923

p21 activated kinase binding domain
1. cd01093 (CRIB_PAK_like)
  
  492 - 535
  
  CDD
  cd01093 (CRIB_PAK_like)
IPR011009

Protein kinase-like domain
1. SSF56112 (Protein k...)
  
  1,067 - 1,329
  
  SUPERFAMILY
  SSF56112 (Protein kinase-like (PK-like))
IPR000719

Protein kinase domain
1. PS50011 (PROTEIN_KI...)
  
  1,075 - 1,326
  
  PROSITE profiles
  PS50011 (PROTEIN_KINASE_DOM)
2. SM00220 (serkin_6)
  
  1,075 - 1,326
  
  SMART
  SM00220 (serkin_6)
3. PF00069 (Pkinase)
  
  1,075 - 1,326
  
  Pfam
  PF00069 (Pkinase)
IPR017441

Protein kinase, ATP binding site
1. PS00107 (PROTEIN_KI...)
  
  1,081 - 1,104
  
  PROSITE patterns
  PS00107 (PROTEIN_KINASE_ATP)
IPR008271

Serine/threonine-protein kinase, active site
1. PS00108 (PROTEIN_KI...)
  
  1,190 - 1,202
  
  PROSITE patterns
  PS00108 (PROTEIN_KINASE_ST)

no IPR

Unintegrated signatures

Coil

976 - 1,003

COILS
Coil (Coil)
G3DSA:1.10.51...

630 - 1,014

GENE3D
G3DSA:1.10.510.10 (G3DSA:1.10.510.10)

1,289 - 1,328

GENE3D
G3DSA:1.10.510.10 (G3DSA:1.10.510.10)

1,141 - 1,288

GENE3D
G3DSA:1.10.510.10 (G3DSA:1.10.510.10)
G3DSA:3.30.20...

1,071 - 1,140

GENE3D
G3DSA:3.30.200.20 (G3DSA:3.30.200.20)
cd06614 (STKc_PAK)

1,074 - 1,327

CDD
cd06614 (STKc_PAK)
mobidb-lite (disord...)

1,007 - 1,053

MobiDB Lite
mobidb-lite (disorder_prediction)

935 - 967

MobiDB Lite
mobidb-lite (disorder_prediction)

768 - 912

MobiDB Lite
mobidb-lite (disorder_prediction)

276 - 298

MobiDB Lite
mobidb-lite (disorder_prediction)

612 - 756

MobiDB Lite
mobidb-lite (disorder_prediction)

158 - 191

MobiDB Lite
mobidb-lite (disorder_prediction)

392 - 489

MobiDB Lite
mobidb-lite (disorder_prediction)

312 - 370

MobiDB Lite
mobidb-lite (disorder_prediction)

204 - 256

MobiDB Lite
mobidb-lite (disorder_prediction)

571 - 599

MobiDB Lite
mobidb-lite (disorder_prediction)

1 - 48

MobiDB Lite
mobidb-lite (disorder_prediction)

Residue annotation

GTPase interaction...

492I

GTPase interaction site
492I, 495P, 498M, 500I, 503H, 520W, 524L
CDD
cd01093 (CRIB_PAK_like)

495P

GTPase interaction site
492I, 495P, 498M, 500I, 503H, 520W, 524L
CDD
cd01093 (CRIB_PAK_like)

498M

GTPase interaction site
492I, 495P, 498M, 500I, 503H, 520W, 524L
CDD
cd01093 (CRIB_PAK_like)

500I

GTPase interaction site
492I, 495P, 498M, 500I, 503H, 520W, 524L
CDD
cd01093 (CRIB_PAK_like)

503H

GTPase interaction site
492I, 495P, 498M, 500I, 503H, 520W, 524L
CDD
cd01093 (CRIB_PAK_like)

520W

GTPase interaction site
492I, 495P, 498M, 500I, 503H, 520W, 524L
CDD
cd01093 (CRIB_PAK_like)

524L

GTPase interaction site
492I, 495P, 498M, 500I, 503H, 520W, 524L
CDD
cd01093 (CRIB_PAK_like)
ATP binding site c...

1,081I

ATP binding site
1,081I, 1,082G, 1,083Q, 1,084G, 1,085G, 1,089V, 1,102A, 1,104K, 1,133V, 1,149M, 1,150E, 1,151Y, 1,152M, 1,153E, 1,155G, 1,156N, 1,159D, 1,198D, 1,199N, 1,201L, 1,211T, 1,212D
CDD
cd06614 (STKc_PAK)

1,082G

ATP binding site
1,081I, 1,082G, 1,083Q, 1,084G, 1,085G, 1,089V, 1,102A, 1,104K, 1,133V, 1,149M, 1,150E, 1,151Y, 1,152M, 1,153E, 1,155G, 1,156N, 1,159D, 1,198D, 1,199N, 1,201L, 1,211T, 1,212D
CDD
cd06614 (STKc_PAK)

1,083Q

ATP binding site
1,081I, 1,082G, 1,083Q, 1,084G, 1,085G, 1,089V, 1,102A, 1,104K, 1,133V, 1,149M, 1,150E, 1,151Y, 1,152M, 1,153E, 1,155G, 1,156N, 1,159D, 1,198D, 1,199N, 1,201L, 1,211T, 1,212D
CDD
cd06614 (STKc_PAK)

1,084G

ATP binding site
1,081I, 1,082G, 1,083Q, 1,084G, 1,085G, 1,089V, 1,102A, 1,104K, 1,133V, 1,149M, 1,150E, 1,151Y, 1,152M, 1,153E, 1,155G, 1,156N, 1,159D, 1,198D, 1,199N, 1,201L, 1,211T, 1,212D
CDD
cd06614 (STKc_PAK)

1,085G

ATP binding site
1,081I, 1,082G, 1,083Q, 1,084G, 1,085G, 1,089V, 1,102A, 1,104K, 1,133V, 1,149M, 1,150E, 1,151Y, 1,152M, 1,153E, 1,155G, 1,156N, 1,159D, 1,198D, 1,199N, 1,201L, 1,211T, 1,212D
CDD
cd06614 (STKc_PAK)

1,089V

ATP binding site
1,081I, 1,082G, 1,083Q, 1,084G, 1,085G, 1,089V, 1,102A, 1,104K, 1,133V, 1,149M, 1,150E, 1,151Y, 1,152M, 1,153E, 1,155G, 1,156N, 1,159D, 1,198D, 1,199N, 1,201L, 1,211T, 1,212D
CDD
cd06614 (STKc_PAK)

1,102A

ATP binding site
1,081I, 1,082G, 1,083Q, 1,084G, 1,085G, 1,089V, 1,102A, 1,104K, 1,133V, 1,149M, 1,150E, 1,151Y, 1,152M, 1,153E, 1,155G, 1,156N, 1,159D, 1,198D, 1,199N, 1,201L, 1,211T, 1,212D
CDD
cd06614 (STKc_PAK)

1,104K

ATP binding site
1,081I, 1,082G, 1,083Q, 1,084G, 1,085G, 1,089V, 1,102A, 1,104K, 1,133V, 1,149M, 1,150E, 1,151Y, 1,152M, 1,153E, 1,155G, 1,156N, 1,159D, 1,198D, 1,199N, 1,201L, 1,211T, 1,212D
CDD
cd06614 (STKc_PAK)

1,133V

ATP binding site
1,081I, 1,082G, 1,083Q, 1,084G, 1,085G, 1,089V, 1,102A, 1,104K, 1,133V, 1,149M, 1,150E, 1,151Y, 1,152M, 1,153E, 1,155G, 1,156N, 1,159D, 1,198D, 1,199N, 1,201L, 1,211T, 1,212D
CDD
cd06614 (STKc_PAK)

1,149M

ATP binding site
1,081I, 1,082G, 1,083Q, 1,084G, 1,085G, 1,089V, 1,102A, 1,104K, 1,133V, 1,149M, 1,150E, 1,151Y, 1,152M, 1,153E, 1,155G, 1,156N, 1,159D, 1,198D, 1,199N, 1,201L, 1,211T, 1,212D
CDD
cd06614 (STKc_PAK)

1,150E

ATP binding site
1,081I, 1,082G, 1,083Q, 1,084G, 1,085G, 1,089V, 1,102A, 1,104K, 1,133V, 1,149M, 1,150E, 1,151Y, 1,152M, 1,153E, 1,155G, 1,156N, 1,159D, 1,198D, 1,199N, 1,201L, 1,211T, 1,212D
CDD
cd06614 (STKc_PAK)

1,151Y

ATP binding site
1,081I, 1,082G, 1,083Q, 1,084G, 1,085G, 1,089V, 1,102A, 1,104K, 1,133V, 1,149M, 1,150E, 1,151Y, 1,152M, 1,153E, 1,155G, 1,156N, 1,159D, 1,198D, 1,199N, 1,201L, 1,211T, 1,212D
CDD
cd06614 (STKc_PAK)

1,152M

ATP binding site
1,081I, 1,082G, 1,083Q, 1,084G, 1,085G, 1,089V, 1,102A, 1,104K, 1,133V, 1,149M, 1,150E, 1,151Y, 1,152M, 1,153E, 1,155G, 1,156N, 1,159D, 1,198D, 1,199N, 1,201L, 1,211T, 1,212D
CDD
cd06614 (STKc_PAK)

1,153E

ATP binding site
1,081I, 1,082G, 1,083Q, 1,084G, 1,085G, 1,089V, 1,102A, 1,104K, 1,133V, 1,149M, 1,150E, 1,151Y, 1,152M, 1,153E, 1,155G, 1,156N, 1,159D, 1,198D, 1,199N, 1,201L, 1,211T, 1,212D
CDD
cd06614 (STKc_PAK)

1,155G

ATP binding site
1,081I, 1,082G, 1,083Q, 1,084G, 1,085G, 1,089V, 1,102A, 1,104K, 1,133V, 1,149M, 1,150E, 1,151Y, 1,152M, 1,153E, 1,155G, 1,156N, 1,159D, 1,198D, 1,199N, 1,201L, 1,211T, 1,212D
CDD
cd06614 (STKc_PAK)

1,156N

ATP binding site
1,081I, 1,082G, 1,083Q, 1,084G, 1,085G, 1,089V, 1,102A, 1,104K, 1,133V, 1,149M, 1,150E, 1,151Y, 1,152M, 1,153E, 1,155G, 1,156N, 1,159D, 1,198D, 1,199N, 1,201L, 1,211T, 1,212D
CDD
cd06614 (STKc_PAK)

1,159D

ATP binding site
1,081I, 1,082G, 1,083Q, 1,084G, 1,085G, 1,089V, 1,102A, 1,104K, 1,133V, 1,149M, 1,150E, 1,151Y, 1,152M, 1,153E, 1,155G, 1,156N, 1,159D, 1,198D, 1,199N, 1,201L, 1,211T, 1,212D
CDD
cd06614 (STKc_PAK)

1,198D

ATP binding site
1,081I, 1,082G, 1,083Q, 1,084G, 1,085G, 1,089V, 1,102A, 1,104K, 1,133V, 1,149M, 1,150E, 1,151Y, 1,152M, 1,153E, 1,155G, 1,156N, 1,159D, 1,198D, 1,199N, 1,201L, 1,211T, 1,212D
CDD
cd06614 (STKc_PAK)

1,199N

ATP binding site
1,081I, 1,082G, 1,083Q, 1,084G, 1,085G, 1,089V, 1,102A, 1,104K, 1,133V, 1,149M, 1,150E, 1,151Y, 1,152M, 1,153E, 1,155G, 1,156N, 1,159D, 1,198D, 1,199N, 1,201L, 1,211T, 1,212D
CDD
cd06614 (STKc_PAK)

1,201L

ATP binding site
1,081I, 1,082G, 1,083Q, 1,084G, 1,085G, 1,089V, 1,102A, 1,104K, 1,133V, 1,149M, 1,150E, 1,151Y, 1,152M, 1,153E, 1,155G, 1,156N, 1,159D, 1,198D, 1,199N, 1,201L, 1,211T, 1,212D
CDD
cd06614 (STKc_PAK)

1,211T

ATP binding site
1,081I, 1,082G, 1,083Q, 1,084G, 1,085G, 1,089V, 1,102A, 1,104K, 1,133V, 1,149M, 1,150E, 1,151Y, 1,152M, 1,153E, 1,155G, 1,156N, 1,159D, 1,198D, 1,199N, 1,201L, 1,211T, 1,212D
CDD
cd06614 (STKc_PAK)

1,212D

ATP binding site
1,081I, 1,082G, 1,083Q, 1,084G, 1,085G, 1,089V, 1,102A, 1,104K, 1,133V, 1,149M, 1,150E, 1,151Y, 1,152M, 1,153E, 1,155G, 1,156N, 1,159D, 1,198D, 1,199N, 1,201L, 1,211T, 1,212D
CDD
cd06614 (STKc_PAK)
active site cd06614

1,081I

active site
1,081I, 1,082G, 1,083Q, 1,084G, 1,085G, 1,089V, 1,102A, 1,104K, 1,133V, 1,149M, 1,150E, 1,151Y, 1,152M, 1,153E, 1,155G, 1,156N, 1,159D, 1,194D, 1,196K, 1,197S, 1,198D, 1,199N, 1,201L, 1,211T, 1,212D, 1,215F, 1,228T, 1,229I, 1,230V, 1,231G, 1,232T, 1,234Y, 1,261E, 1,270L, 1,271N, 1,272E
CDD
cd06614 (STKc_PAK)

1,082G

active site
1,081I, 1,082G, 1,083Q, 1,084G, 1,085G, 1,089V, 1,102A, 1,104K, 1,133V, 1,149M, 1,150E, 1,151Y, 1,152M, 1,153E, 1,155G, 1,156N, 1,159D, 1,194D, 1,196K, 1,197S, 1,198D, 1,199N, 1,201L, 1,211T, 1,212D, 1,215F, 1,228T, 1,229I, 1,230V, 1,231G, 1,232T, 1,234Y, 1,261E, 1,270L, 1,271N, 1,272E
CDD
cd06614 (STKc_PAK)

1,083Q

active site
1,081I, 1,082G, 1,083Q, 1,084G, 1,085G, 1,089V, 1,102A, 1,104K, 1,133V, 1,149M, 1,150E, 1,151Y, 1,152M, 1,153E, 1,155G, 1,156N, 1,159D, 1,194D, 1,196K, 1,197S, 1,198D, 1,199N, 1,201L, 1,211T, 1,212D, 1,215F, 1,228T, 1,229I, 1,230V, 1,231G, 1,232T, 1,234Y, 1,261E, 1,270L, 1,271N, 1,272E
CDD
cd06614 (STKc_PAK)

1,084G

active site
1,081I, 1,082G, 1,083Q, 1,084G, 1,085G, 1,089V, 1,102A, 1,104K, 1,133V, 1,149M, 1,150E, 1,151Y, 1,152M, 1,153E, 1,155G, 1,156N, 1,159D, 1,194D, 1,196K, 1,197S, 1,198D, 1,199N, 1,201L, 1,211T, 1,212D, 1,215F, 1,228T, 1,229I, 1,230V, 1,231G, 1,232T, 1,234Y, 1,261E, 1,270L, 1,271N, 1,272E
CDD
cd06614 (STKc_PAK)

1,085G

active site
1,081I, 1,082G, 1,083Q, 1,084G, 1,085G, 1,089V, 1,102A, 1,104K, 1,133V, 1,149M, 1,150E, 1,151Y, 1,152M, 1,153E, 1,155G, 1,156N, 1,159D, 1,194D, 1,196K, 1,197S, 1,198D, 1,199N, 1,201L, 1,211T, 1,212D, 1,215F, 1,228T, 1,229I, 1,230V, 1,231G, 1,232T, 1,234Y, 1,261E, 1,270L, 1,271N, 1,272E
CDD
cd06614 (STKc_PAK)

1,089V

active site
1,081I, 1,082G, 1,083Q, 1,084G, 1,085G, 1,089V, 1,102A, 1,104K, 1,133V, 1,149M, 1,150E, 1,151Y, 1,152M, 1,153E, 1,155G, 1,156N, 1,159D, 1,194D, 1,196K, 1,197S, 1,198D, 1,199N, 1,201L, 1,211T, 1,212D, 1,215F, 1,228T, 1,229I, 1,230V, 1,231G, 1,232T, 1,234Y, 1,261E, 1,270L, 1,271N, 1,272E
CDD
cd06614 (STKc_PAK)

1,102A

active site
1,081I, 1,082G, 1,083Q, 1,084G, 1,085G, 1,089V, 1,102A, 1,104K, 1,133V, 1,149M, 1,150E, 1,151Y, 1,152M, 1,153E, 1,155G, 1,156N, 1,159D, 1,194D, 1,196K, 1,197S, 1,198D, 1,199N, 1,201L, 1,211T, 1,212D, 1,215F, 1,228T, 1,229I, 1,230V, 1,231G, 1,232T, 1,234Y, 1,261E, 1,270L, 1,271N, 1,272E
CDD
cd06614 (STKc_PAK)

1,104K

active site
1,081I, 1,082G, 1,083Q, 1,084G, 1,085G, 1,089V, 1,102A, 1,104K, 1,133V, 1,149M, 1,150E, 1,151Y, 1,152M, 1,153E, 1,155G, 1,156N, 1,159D, 1,194D, 1,196K, 1,197S, 1,198D, 1,199N, 1,201L, 1,211T, 1,212D, 1,215F, 1,228T, 1,229I, 1,230V, 1,231G, 1,232T, 1,234Y, 1,261E, 1,270L, 1,271N, 1,272E
CDD
cd06614 (STKc_PAK)

1,133V

active site
1,081I, 1,082G, 1,083Q, 1,084G, 1,085G, 1,089V, 1,102A, 1,104K, 1,133V, 1,149M, 1,150E, 1,151Y, 1,152M, 1,153E, 1,155G, 1,156N, 1,159D, 1,194D, 1,196K, 1,197S, 1,198D, 1,199N, 1,201L, 1,211T, 1,212D, 1,215F, 1,228T, 1,229I, 1,230V, 1,231G, 1,232T, 1,234Y, 1,261E, 1,270L, 1,271N, 1,272E
CDD
cd06614 (STKc_PAK)

1,149M

active site
1,081I, 1,082G, 1,083Q, 1,084G, 1,085G, 1,089V, 1,102A, 1,104K, 1,133V, 1,149M, 1,150E, 1,151Y, 1,152M, 1,153E, 1,155G, 1,156N, 1,159D, 1,194D, 1,196K, 1,197S, 1,198D, 1,199N, 1,201L, 1,211T, 1,212D, 1,215F, 1,228T, 1,229I, 1,230V, 1,231G, 1,232T, 1,234Y, 1,261E, 1,270L, 1,271N, 1,272E
CDD
cd06614 (STKc_PAK)

1,150E

active site
1,081I, 1,082G, 1,083Q, 1,084G, 1,085G, 1,089V, 1,102A, 1,104K, 1,133V, 1,149M, 1,150E, 1,151Y, 1,152M, 1,153E, 1,155G, 1,156N, 1,159D, 1,194D, 1,196K, 1,197S, 1,198D, 1,199N, 1,201L, 1,211T, 1,212D, 1,215F, 1,228T, 1,229I, 1,230V, 1,231G, 1,232T, 1,234Y, 1,261E, 1,270L, 1,271N, 1,272E
CDD
cd06614 (STKc_PAK)

1,151Y

active site
1,081I, 1,082G, 1,083Q, 1,084G, 1,085G, 1,089V, 1,102A, 1,104K, 1,133V, 1,149M, 1,150E, 1,151Y, 1,152M, 1,153E, 1,155G, 1,156N, 1,159D, 1,194D, 1,196K, 1,197S, 1,198D, 1,199N, 1,201L, 1,211T, 1,212D, 1,215F, 1,228T, 1,229I, 1,230V, 1,231G, 1,232T, 1,234Y, 1,261E, 1,270L, 1,271N, 1,272E
CDD
cd06614 (STKc_PAK)

1,152M

active site
1,081I, 1,082G, 1,083Q, 1,084G, 1,085G, 1,089V, 1,102A, 1,104K, 1,133V, 1,149M, 1,150E, 1,151Y, 1,152M, 1,153E, 1,155G, 1,156N, 1,159D, 1,194D, 1,196K, 1,197S, 1,198D, 1,199N, 1,201L, 1,211T, 1,212D, 1,215F, 1,228T, 1,229I, 1,230V, 1,231G, 1,232T, 1,234Y, 1,261E, 1,270L, 1,271N, 1,272E
CDD
cd06614 (STKc_PAK)

1,153E

active site
1,081I, 1,082G, 1,083Q, 1,084G, 1,085G, 1,089V, 1,102A, 1,104K, 1,133V, 1,149M, 1,150E, 1,151Y, 1,152M, 1,153E, 1,155G, 1,156N, 1,159D, 1,194D, 1,196K, 1,197S, 1,198D, 1,199N, 1,201L, 1,211T, 1,212D, 1,215F, 1,228T, 1,229I, 1,230V, 1,231G, 1,232T, 1,234Y, 1,261E, 1,270L, 1,271N, 1,272E
CDD
cd06614 (STKc_PAK)

1,155G

active site
1,081I, 1,082G, 1,083Q, 1,084G, 1,085G, 1,089V, 1,102A, 1,104K, 1,133V, 1,149M, 1,150E, 1,151Y, 1,152M, 1,153E, 1,155G, 1,156N, 1,159D, 1,194D, 1,196K, 1,197S, 1,198D, 1,199N, 1,201L, 1,211T, 1,212D, 1,215F, 1,228T, 1,229I, 1,230V, 1,231G, 1,232T, 1,234Y, 1,261E, 1,270L, 1,271N, 1,272E
CDD
cd06614 (STKc_PAK)

1,156N

active site
1,081I, 1,082G, 1,083Q, 1,084G, 1,085G, 1,089V, 1,102A, 1,104K, 1,133V, 1,149M, 1,150E, 1,151Y, 1,152M, 1,153E, 1,155G, 1,156N, 1,159D, 1,194D, 1,196K, 1,197S, 1,198D, 1,199N, 1,201L, 1,211T, 1,212D, 1,215F, 1,228T, 1,229I, 1,230V, 1,231G, 1,232T, 1,234Y, 1,261E, 1,270L, 1,271N, 1,272E
CDD
cd06614 (STKc_PAK)

1,159D

active site
1,081I, 1,082G, 1,083Q, 1,084G, 1,085G, 1,089V, 1,102A, 1,104K, 1,133V, 1,149M, 1,150E, 1,151Y, 1,152M, 1,153E, 1,155G, 1,156N, 1,159D, 1,194D, 1,196K, 1,197S, 1,198D, 1,199N, 1,201L, 1,211T, 1,212D, 1,215F, 1,228T, 1,229I, 1,230V, 1,231G, 1,232T, 1,234Y, 1,261E, 1,270L, 1,271N, 1,272E
CDD
cd06614 (STKc_PAK)

1,194D

active site
1,081I, 1,082G, 1,083Q, 1,084G, 1,085G, 1,089V, 1,102A, 1,104K, 1,133V, 1,149M, 1,150E, 1,151Y, 1,152M, 1,153E, 1,155G, 1,156N, 1,159D, 1,194D, 1,196K, 1,197S, 1,198D, 1,199N, 1,201L, 1,211T, 1,212D, 1,215F, 1,228T, 1,229I, 1,230V, 1,231G, 1,232T, 1,234Y, 1,261E, 1,270L, 1,271N, 1,272E
CDD
cd06614 (STKc_PAK)

1,196K

active site
1,081I, 1,082G, 1,083Q, 1,084G, 1,085G, 1,089V, 1,102A, 1,104K, 1,133V, 1,149M, 1,150E, 1,151Y, 1,152M, 1,153E, 1,155G, 1,156N, 1,159D, 1,194D, 1,196K, 1,197S, 1,198D, 1,199N, 1,201L, 1,211T, 1,212D, 1,215F, 1,228T, 1,229I, 1,230V, 1,231G, 1,232T, 1,234Y, 1,261E, 1,270L, 1,271N, 1,272E
CDD
cd06614 (STKc_PAK)

1,197S

active site
1,081I, 1,082G, 1,083Q, 1,084G, 1,085G, 1,089V, 1,102A, 1,104K, 1,133V, 1,149M, 1,150E, 1,151Y, 1,152M, 1,153E, 1,155G, 1,156N, 1,159D, 1,194D, 1,196K, 1,197S, 1,198D, 1,199N, 1,201L, 1,211T, 1,212D, 1,215F, 1,228T, 1,229I, 1,230V, 1,231G, 1,232T, 1,234Y, 1,261E, 1,270L, 1,271N, 1,272E
CDD
cd06614 (STKc_PAK)

1,198D

active site
1,081I, 1,082G, 1,083Q, 1,084G, 1,085G, 1,089V, 1,102A, 1,104K, 1,133V, 1,149M, 1,150E, 1,151Y, 1,152M, 1,153E, 1,155G, 1,156N, 1,159D, 1,194D, 1,196K, 1,197S, 1,198D, 1,199N, 1,201L, 1,211T, 1,212D, 1,215F, 1,228T, 1,229I, 1,230V, 1,231G, 1,232T, 1,234Y, 1,261E, 1,270L, 1,271N, 1,272E
CDD
cd06614 (STKc_PAK)

1,199N

active site
1,081I, 1,082G, 1,083Q, 1,084G, 1,085G, 1,089V, 1,102A, 1,104K, 1,133V, 1,149M, 1,150E, 1,151Y, 1,152M, 1,153E, 1,155G, 1,156N, 1,159D, 1,194D, 1,196K, 1,197S, 1,198D, 1,199N, 1,201L, 1,211T, 1,212D, 1,215F, 1,228T, 1,229I, 1,230V, 1,231G, 1,232T, 1,234Y, 1,261E, 1,270L, 1,271N, 1,272E
CDD
cd06614 (STKc_PAK)

1,201L

active site
1,081I, 1,082G, 1,083Q, 1,084G, 1,085G, 1,089V, 1,102A, 1,104K, 1,133V, 1,149M, 1,150E, 1,151Y, 1,152M, 1,153E, 1,155G, 1,156N, 1,159D, 1,194D, 1,196K, 1,197S, 1,198D, 1,199N, 1,201L, 1,211T, 1,212D, 1,215F, 1,228T, 1,229I, 1,230V, 1,231G, 1,232T, 1,234Y, 1,261E, 1,270L, 1,271N, 1,272E
CDD
cd06614 (STKc_PAK)

1,211T

active site
1,081I, 1,082G, 1,083Q, 1,084G, 1,085G, 1,089V, 1,102A, 1,104K, 1,133V, 1,149M, 1,150E, 1,151Y, 1,152M, 1,153E, 1,155G, 1,156N, 1,159D, 1,194D, 1,196K, 1,197S, 1,198D, 1,199N, 1,201L, 1,211T, 1,212D, 1,215F, 1,228T, 1,229I, 1,230V, 1,231G, 1,232T, 1,234Y, 1,261E, 1,270L, 1,271N, 1,272E
CDD
cd06614 (STKc_PAK)

1,212D

active site
1,081I, 1,082G, 1,083Q, 1,084G, 1,085G, 1,089V, 1,102A, 1,104K, 1,133V, 1,149M, 1,150E, 1,151Y, 1,152M, 1,153E, 1,155G, 1,156N, 1,159D, 1,194D, 1,196K, 1,197S, 1,198D, 1,199N, 1,201L, 1,211T, 1,212D, 1,215F, 1,228T, 1,229I, 1,230V, 1,231G, 1,232T, 1,234Y, 1,261E, 1,270L, 1,271N, 1,272E
CDD
cd06614 (STKc_PAK)

1,215F

active site
1,081I, 1,082G, 1,083Q, 1,084G, 1,085G, 1,089V, 1,102A, 1,104K, 1,133V, 1,149M, 1,150E, 1,151Y, 1,152M, 1,153E, 1,155G, 1,156N, 1,159D, 1,194D, 1,196K, 1,197S, 1,198D, 1,199N, 1,201L, 1,211T, 1,212D, 1,215F, 1,228T, 1,229I, 1,230V, 1,231G, 1,232T, 1,234Y, 1,261E, 1,270L, 1,271N, 1,272E
CDD
cd06614 (STKc_PAK)

1,228T

active site
1,081I, 1,082G, 1,083Q, 1,084G, 1,085G, 1,089V, 1,102A, 1,104K, 1,133V, 1,149M, 1,150E, 1,151Y, 1,152M, 1,153E, 1,155G, 1,156N, 1,159D, 1,194D, 1,196K, 1,197S, 1,198D, 1,199N, 1,201L, 1,211T, 1,212D, 1,215F, 1,228T, 1,229I, 1,230V, 1,231G, 1,232T, 1,234Y, 1,261E, 1,270L, 1,271N, 1,272E
CDD
cd06614 (STKc_PAK)

1,229I

active site
1,081I, 1,082G, 1,083Q, 1,084G, 1,085G, 1,089V, 1,102A, 1,104K, 1,133V, 1,149M, 1,150E, 1,151Y, 1,152M, 1,153E, 1,155G, 1,156N, 1,159D, 1,194D, 1,196K, 1,197S, 1,198D, 1,199N, 1,201L, 1,211T, 1,212D, 1,215F, 1,228T, 1,229I, 1,230V, 1,231G, 1,232T, 1,234Y, 1,261E, 1,270L, 1,271N, 1,272E
CDD
cd06614 (STKc_PAK)

1,230V

active site
1,081I, 1,082G, 1,083Q, 1,084G, 1,085G, 1,089V, 1,102A, 1,104K, 1,133V, 1,149M, 1,150E, 1,151Y, 1,152M, 1,153E, 1,155G, 1,156N, 1,159D, 1,194D, 1,196K, 1,197S, 1,198D, 1,199N, 1,201L, 1,211T, 1,212D, 1,215F, 1,228T, 1,229I, 1,230V, 1,231G, 1,232T, 1,234Y, 1,261E, 1,270L, 1,271N, 1,272E
CDD
cd06614 (STKc_PAK)

1,231G

active site
1,081I, 1,082G, 1,083Q, 1,084G, 1,085G, 1,089V, 1,102A, 1,104K, 1,133V, 1,149M, 1,150E, 1,151Y, 1,152M, 1,153E, 1,155G, 1,156N, 1,159D, 1,194D, 1,196K, 1,197S, 1,198D, 1,199N, 1,201L, 1,211T, 1,212D, 1,215F, 1,228T, 1,229I, 1,230V, 1,231G, 1,232T, 1,234Y, 1,261E, 1,270L, 1,271N, 1,272E
CDD
cd06614 (STKc_PAK)

1,232T

active site
1,081I, 1,082G, 1,083Q, 1,084G, 1,085G, 1,089V, 1,102A, 1,104K, 1,133V, 1,149M, 1,150E, 1,151Y, 1,152M, 1,153E, 1,155G, 1,156N, 1,159D, 1,194D, 1,196K, 1,197S, 1,198D, 1,199N, 1,201L, 1,211T, 1,212D, 1,215F, 1,228T, 1,229I, 1,230V, 1,231G, 1,232T, 1,234Y, 1,261E, 1,270L, 1,271N, 1,272E
CDD
cd06614 (STKc_PAK)

1,234Y

active site
1,081I, 1,082G, 1,083Q, 1,084G, 1,085G, 1,089V, 1,102A, 1,104K, 1,133V, 1,149M, 1,150E, 1,151Y, 1,152M, 1,153E, 1,155G, 1,156N, 1,159D, 1,194D, 1,196K, 1,197S, 1,198D, 1,199N, 1,201L, 1,211T, 1,212D, 1,215F, 1,228T, 1,229I, 1,230V, 1,231G, 1,232T, 1,234Y, 1,261E, 1,270L, 1,271N, 1,272E
CDD
cd06614 (STKc_PAK)

1,261E

active site
1,081I, 1,082G, 1,083Q, 1,084G, 1,085G, 1,089V, 1,102A, 1,104K, 1,133V, 1,149M, 1,150E, 1,151Y, 1,152M, 1,153E, 1,155G, 1,156N, 1,159D, 1,194D, 1,196K, 1,197S, 1,198D, 1,199N, 1,201L, 1,211T, 1,212D, 1,215F, 1,228T, 1,229I, 1,230V, 1,231G, 1,232T, 1,234Y, 1,261E, 1,270L, 1,271N, 1,272E
CDD
cd06614 (STKc_PAK)

1,270L

active site
1,081I, 1,082G, 1,083Q, 1,084G, 1,085G, 1,089V, 1,102A, 1,104K, 1,133V, 1,149M, 1,150E, 1,151Y, 1,152M, 1,153E, 1,155G, 1,156N, 1,159D, 1,194D, 1,196K, 1,197S, 1,198D, 1,199N, 1,201L, 1,211T, 1,212D, 1,215F, 1,228T, 1,229I, 1,230V, 1,231G, 1,232T, 1,234Y, 1,261E, 1,270L, 1,271N, 1,272E
CDD
cd06614 (STKc_PAK)

1,271N

active site
1,081I, 1,082G, 1,083Q, 1,084G, 1,085G, 1,089V, 1,102A, 1,104K, 1,133V, 1,149M, 1,150E, 1,151Y, 1,152M, 1,153E, 1,155G, 1,156N, 1,159D, 1,194D, 1,196K, 1,197S, 1,198D, 1,199N, 1,201L, 1,211T, 1,212D, 1,215F, 1,228T, 1,229I, 1,230V, 1,231G, 1,232T, 1,234Y, 1,261E, 1,270L, 1,271N, 1,272E
CDD
cd06614 (STKc_PAK)

1,272E

active site
1,081I, 1,082G, 1,083Q, 1,084G, 1,085G, 1,089V, 1,102A, 1,104K, 1,133V, 1,149M, 1,150E, 1,151Y, 1,152M, 1,153E, 1,155G, 1,156N, 1,159D, 1,194D, 1,196K, 1,197S, 1,198D, 1,199N, 1,201L, 1,211T, 1,212D, 1,215F, 1,228T, 1,229I, 1,230V, 1,231G, 1,232T, 1,234Y, 1,261E, 1,270L, 1,271N, 1,272E
CDD
cd06614 (STKc_PAK)
polypeptide substr...

1,084G

polypeptide substrate binding site
1,084G, 1,085G, 1,194D, 1,196K, 1,197S, 1,198D, 1,215F, 1,228T, 1,229I, 1,230V, 1,231G, 1,232T, 1,234Y, 1,261E, 1,270L, 1,271N, 1,272E
CDD
cd06614 (STKc_PAK)

1,085G

polypeptide substrate binding site
1,084G, 1,085G, 1,194D, 1,196K, 1,197S, 1,198D, 1,215F, 1,228T, 1,229I, 1,230V, 1,231G, 1,232T, 1,234Y, 1,261E, 1,270L, 1,271N, 1,272E
CDD
cd06614 (STKc_PAK)

1,194D

polypeptide substrate binding site
1,084G, 1,085G, 1,194D, 1,196K, 1,197S, 1,198D, 1,215F, 1,228T, 1,229I, 1,230V, 1,231G, 1,232T, 1,234Y, 1,261E, 1,270L, 1,271N, 1,272E
CDD
cd06614 (STKc_PAK)

1,196K

polypeptide substrate binding site
1,084G, 1,085G, 1,194D, 1,196K, 1,197S, 1,198D, 1,215F, 1,228T, 1,229I, 1,230V, 1,231G, 1,232T, 1,234Y, 1,261E, 1,270L, 1,271N, 1,272E
CDD
cd06614 (STKc_PAK)

1,197S

polypeptide substrate binding site
1,084G, 1,085G, 1,194D, 1,196K, 1,197S, 1,198D, 1,215F, 1,228T, 1,229I, 1,230V, 1,231G, 1,232T, 1,234Y, 1,261E, 1,270L, 1,271N, 1,272E
CDD
cd06614 (STKc_PAK)

1,198D

polypeptide substrate binding site
1,084G, 1,085G, 1,194D, 1,196K, 1,197S, 1,198D, 1,215F, 1,228T, 1,229I, 1,230V, 1,231G, 1,232T, 1,234Y, 1,261E, 1,270L, 1,271N, 1,272E
CDD
cd06614 (STKc_PAK)

1,215F

polypeptide substrate binding site
1,084G, 1,085G, 1,194D, 1,196K, 1,197S, 1,198D, 1,215F, 1,228T, 1,229I, 1,230V, 1,231G, 1,232T, 1,234Y, 1,261E, 1,270L, 1,271N, 1,272E
CDD
cd06614 (STKc_PAK)

1,228T

polypeptide substrate binding site
1,084G, 1,085G, 1,194D, 1,196K, 1,197S, 1,198D, 1,215F, 1,228T, 1,229I, 1,230V, 1,231G, 1,232T, 1,234Y, 1,261E, 1,270L, 1,271N, 1,272E
CDD
cd06614 (STKc_PAK)

1,229I

polypeptide substrate binding site
1,084G, 1,085G, 1,194D, 1,196K, 1,197S, 1,198D, 1,215F, 1,228T, 1,229I, 1,230V, 1,231G, 1,232T, 1,234Y, 1,261E, 1,270L, 1,271N, 1,272E
CDD
cd06614 (STKc_PAK)

1,230V

polypeptide substrate binding site
1,084G, 1,085G, 1,194D, 1,196K, 1,197S, 1,198D, 1,215F, 1,228T, 1,229I, 1,230V, 1,231G, 1,232T, 1,234Y, 1,261E, 1,270L, 1,271N, 1,272E
CDD
cd06614 (STKc_PAK)

1,231G

polypeptide substrate binding site
1,084G, 1,085G, 1,194D, 1,196K, 1,197S, 1,198D, 1,215F, 1,228T, 1,229I, 1,230V, 1,231G, 1,232T, 1,234Y, 1,261E, 1,270L, 1,271N, 1,272E
CDD
cd06614 (STKc_PAK)

1,232T

polypeptide substrate binding site
1,084G, 1,085G, 1,194D, 1,196K, 1,197S, 1,198D, 1,215F, 1,228T, 1,229I, 1,230V, 1,231G, 1,232T, 1,234Y, 1,261E, 1,270L, 1,271N, 1,272E
CDD
cd06614 (STKc_PAK)

1,234Y

polypeptide substrate binding site
1,084G, 1,085G, 1,194D, 1,196K, 1,197S, 1,198D, 1,215F, 1,228T, 1,229I, 1,230V, 1,231G, 1,232T, 1,234Y, 1,261E, 1,270L, 1,271N, 1,272E
CDD
cd06614 (STKc_PAK)

1,261E

polypeptide substrate binding site
1,084G, 1,085G, 1,194D, 1,196K, 1,197S, 1,198D, 1,215F, 1,228T, 1,229I, 1,230V, 1,231G, 1,232T, 1,234Y, 1,261E, 1,270L, 1,271N, 1,272E
CDD
cd06614 (STKc_PAK)

1,270L

polypeptide substrate binding site
1,084G, 1,085G, 1,194D, 1,196K, 1,197S, 1,198D, 1,215F, 1,228T, 1,229I, 1,230V, 1,231G, 1,232T, 1,234Y, 1,261E, 1,270L, 1,271N, 1,272E
CDD
cd06614 (STKc_PAK)

1,271N

polypeptide substrate binding site
1,084G, 1,085G, 1,194D, 1,196K, 1,197S, 1,198D, 1,215F, 1,228T, 1,229I, 1,230V, 1,231G, 1,232T, 1,234Y, 1,261E, 1,270L, 1,271N, 1,272E
CDD
cd06614 (STKc_PAK)

1,272E

polypeptide substrate binding site
1,084G, 1,085G, 1,194D, 1,196K, 1,197S, 1,198D, 1,215F, 1,228T, 1,229I, 1,230V, 1,231G, 1,232T, 1,234Y, 1,261E, 1,270L, 1,271N, 1,272E
CDD
cd06614 (STKc_PAK)
activation loop (A...

1,211T

activation loop (A-loop)
1,211T, 1,212D, 1,213F, 1,214G, 1,215F, 1,216C, 1,217A, 1,218Q, 1,219L, 1,220N, 1,221E, 1,222Y, 1,227T, 1,228T, 1,229I, 1,230V, 1,231G, 1,232T, 1,233P, 1,234Y
CDD
cd06614 (STKc_PAK)

1,212D

activation loop (A-loop)
1,211T, 1,212D, 1,213F, 1,214G, 1,215F, 1,216C, 1,217A, 1,218Q, 1,219L, 1,220N, 1,221E, 1,222Y, 1,227T, 1,228T, 1,229I, 1,230V, 1,231G, 1,232T, 1,233P, 1,234Y
CDD
cd06614 (STKc_PAK)

1,213F

activation loop (A-loop)
1,211T, 1,212D, 1,213F, 1,214G, 1,215F, 1,216C, 1,217A, 1,218Q, 1,219L, 1,220N, 1,221E, 1,222Y, 1,227T, 1,228T, 1,229I, 1,230V, 1,231G, 1,232T, 1,233P, 1,234Y
CDD
cd06614 (STKc_PAK)

1,214G

activation loop (A-loop)
1,211T, 1,212D, 1,213F, 1,214G, 1,215F, 1,216C, 1,217A, 1,218Q, 1,219L, 1,220N, 1,221E, 1,222Y, 1,227T, 1,228T, 1,229I, 1,230V, 1,231G, 1,232T, 1,233P, 1,234Y
CDD
cd06614 (STKc_PAK)

1,215F

activation loop (A-loop)
1,211T, 1,212D, 1,213F, 1,214G, 1,215F, 1,216C, 1,217A, 1,218Q, 1,219L, 1,220N, 1,221E, 1,222Y, 1,227T, 1,228T, 1,229I, 1,230V, 1,231G, 1,232T, 1,233P, 1,234Y
CDD
cd06614 (STKc_PAK)

1,216C

activation loop (A-loop)
1,211T, 1,212D, 1,213F, 1,214G, 1,215F, 1,216C, 1,217A, 1,218Q, 1,219L, 1,220N, 1,221E, 1,222Y, 1,227T, 1,228T, 1,229I, 1,230V, 1,231G, 1,232T, 1,233P, 1,234Y
CDD
cd06614 (STKc_PAK)

1,217A

activation loop (A-loop)
1,211T, 1,212D, 1,213F, 1,214G, 1,215F, 1,216C, 1,217A, 1,218Q, 1,219L, 1,220N, 1,221E, 1,222Y, 1,227T, 1,228T, 1,229I, 1,230V, 1,231G, 1,232T, 1,233P, 1,234Y
CDD
cd06614 (STKc_PAK)

1,218Q

activation loop (A-loop)
1,211T, 1,212D, 1,213F, 1,214G, 1,215F, 1,216C, 1,217A, 1,218Q, 1,219L, 1,220N, 1,221E, 1,222Y, 1,227T, 1,228T, 1,229I, 1,230V, 1,231G, 1,232T, 1,233P, 1,234Y
CDD
cd06614 (STKc_PAK)

1,219L

activation loop (A-loop)
1,211T, 1,212D, 1,213F, 1,214G, 1,215F, 1,216C, 1,217A, 1,218Q, 1,219L, 1,220N, 1,221E, 1,222Y, 1,227T, 1,228T, 1,229I, 1,230V, 1,231G, 1,232T, 1,233P, 1,234Y
CDD
cd06614 (STKc_PAK)

1,220N

activation loop (A-loop)
1,211T, 1,212D, 1,213F, 1,214G, 1,215F, 1,216C, 1,217A, 1,218Q, 1,219L, 1,220N, 1,221E, 1,222Y, 1,227T, 1,228T, 1,229I, 1,230V, 1,231G, 1,232T, 1,233P, 1,234Y
CDD
cd06614 (STKc_PAK)

1,221E

activation loop (A-loop)
1,211T, 1,212D, 1,213F, 1,214G, 1,215F, 1,216C, 1,217A, 1,218Q, 1,219L, 1,220N, 1,221E, 1,222Y, 1,227T, 1,228T, 1,229I, 1,230V, 1,231G, 1,232T, 1,233P, 1,234Y
CDD
cd06614 (STKc_PAK)

1,222Y

activation loop (A-loop)
1,211T, 1,212D, 1,213F, 1,214G, 1,215F, 1,216C, 1,217A, 1,218Q, 1,219L, 1,220N, 1,221E, 1,222Y, 1,227T, 1,228T, 1,229I, 1,230V, 1,231G, 1,232T, 1,233P, 1,234Y
CDD
cd06614 (STKc_PAK)

1,227T

activation loop (A-loop)
1,211T, 1,212D, 1,213F, 1,214G, 1,215F, 1,216C, 1,217A, 1,218Q, 1,219L, 1,220N, 1,221E, 1,222Y, 1,227T, 1,228T, 1,229I, 1,230V, 1,231G, 1,232T, 1,233P, 1,234Y
CDD
cd06614 (STKc_PAK)

1,228T

activation loop (A-loop)
1,211T, 1,212D, 1,213F, 1,214G, 1,215F, 1,216C, 1,217A, 1,218Q, 1,219L, 1,220N, 1,221E, 1,222Y, 1,227T, 1,228T, 1,229I, 1,230V, 1,231G, 1,232T, 1,233P, 1,234Y
CDD
cd06614 (STKc_PAK)

1,229I

activation loop (A-loop)
1,211T, 1,212D, 1,213F, 1,214G, 1,215F, 1,216C, 1,217A, 1,218Q, 1,219L, 1,220N, 1,221E, 1,222Y, 1,227T, 1,228T, 1,229I, 1,230V, 1,231G, 1,232T, 1,233P, 1,234Y
CDD
cd06614 (STKc_PAK)

1,230V

activation loop (A-loop)
1,211T, 1,212D, 1,213F, 1,214G, 1,215F, 1,216C, 1,217A, 1,218Q, 1,219L, 1,220N, 1,221E, 1,222Y, 1,227T, 1,228T, 1,229I, 1,230V, 1,231G, 1,232T, 1,233P, 1,234Y
CDD
cd06614 (STKc_PAK)

1,231G

activation loop (A-loop)
1,211T, 1,212D, 1,213F, 1,214G, 1,215F, 1,216C, 1,217A, 1,218Q, 1,219L, 1,220N, 1,221E, 1,222Y, 1,227T, 1,228T, 1,229I, 1,230V, 1,231G, 1,232T, 1,233P, 1,234Y
CDD
cd06614 (STKc_PAK)

1,232T

activation loop (A-loop)
1,211T, 1,212D, 1,213F, 1,214G, 1,215F, 1,216C, 1,217A, 1,218Q, 1,219L, 1,220N, 1,221E, 1,222Y, 1,227T, 1,228T, 1,229I, 1,230V, 1,231G, 1,232T, 1,233P, 1,234Y
CDD
cd06614 (STKc_PAK)

1,233P

activation loop (A-loop)
1,211T, 1,212D, 1,213F, 1,214G, 1,215F, 1,216C, 1,217A, 1,218Q, 1,219L, 1,220N, 1,221E, 1,222Y, 1,227T, 1,228T, 1,229I, 1,230V, 1,231G, 1,232T, 1,233P, 1,234Y
CDD
cd06614 (STKc_PAK)

1,234Y

activation loop (A-loop)
1,211T, 1,212D, 1,213F, 1,214G, 1,215F, 1,216C, 1,217A, 1,218Q, 1,219L, 1,220N, 1,221E, 1,222Y, 1,227T, 1,228T, 1,229I, 1,230V, 1,231G, 1,232T, 1,233P, 1,234Y
CDD
cd06614 (STKc_PAK)

Protein sequence

>MIA_03434_1
MNAYMYKSPPQSKVANPNRSQTTIIDTDPSSSSEENDPEDHTYEDHNSIYEEYESSPLIDTSHSFDQTPATNNVAVDSAQ
DLDNTHTLTYFDPTQSSHSSLEDVVNNHRYPTNGSANITSPKHFSQAQQLYQRNNLTATPTAPPPSSTQYITSPASVRTT
VPSPTVQDFPLPISNTIDDPVTPSSHYHSQTPQQFAHYSNNYRLSKDHQNPRSSPTYTSSKTSSSTSYSTRENSFGEHSA
NYPASETSTPSIPVKTTDPISHISSLSISSLTSSTSFSFENSRSSQHTSSSRHPSTHLAPAFAGSAIDAIPATPQLPQDH
DVLGRNLNFQSSTPSVSTPAPASSASSSKSSSSSSHHWSMGKQQSNKSTDEISSKLLDAAPISSSSAIDLSTSSFTTAPS
TPLDPVQARKSNPSHPINKSNPIVSPSDRSLTSSSSNENNKRRSTGRARSKTMKGVFSNMFSSMRGGSSSSDSSSSSRRI
SASSDKSGTFKISQPYDMKIVTHVGYDKDNSEFTGIPPEWIKMLTDSGISKKEAEQHPQAVRDVMAFLNNQSDDQEQNVW
KKFDKAKATNPTLKLESLSPTPGTTTGTSTAASSVVSSPVHTLNGSSDYFSAQRQAPSAPKTPSSGASSSSGFTSSPSTN
NFATPTVPIGTATTTNGHESRSRSNSILDGLKKGSGSFKERAQSLRRKPENLKDATLISSPQPIPERKFIPTRPAPRPPG
SPQSPGPLAIGSTTPFAETIDSKIEAQPPRSPISATNTAAALAAITSASAPAPASAPASALASTSTPGTPSFGASSAAIG
TATTTTEVVTSPREATTTSTTSSSSSASTVSMRIDVAKASALASTPSVSTPSTSQQPLATNHHTHPMSPPPRPPPAPPLG
VPSVRSNFDKNRDTQAAQRQPQPGGGLDPAFFSPLQQQHLKHVPSNNQINAGSARIAPQQQVTQQYPQTQPGAGLQGPQT
QQQLQLRLQQQHQWHMQQQQELIQQQNRRLEQQQQQQQQQQQQQLPQSQQAQAQAPSVELSKSEQMAQLASSQSAAASAK
EAAITRRRDARRRRDAEVIARLARICNPDDPTALYKDLHKIGQGGTGGVYTAHHVKTNECVAIKQMNLEEQPKKELIINE
IIVMKESSHRNIVNFIDSYLLHGDLWVVMEYMEGGNLTDVVTYNVMTEGQIGAVCREVLQGLVHLHSKGVIHRDIKSDNI
LLSMRGDIKLTDFGFCAQLNEYNAKRTTIVGTPYWMAPEMVRRTAYGPKIDIWSLGIMAIEMIEGEPPYLNETQHRALYL
IVTNGTPKLKEPEALTEVFTEFLNWALQVDVDERATASQLLKHEFLKTAESVRSLAPLVLNARHQKELDKRSNYAPAPQS
KD

GO term prediction

Biological Process

GO:0006468 protein phosphorylation

Molecular Function

GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0005524 ATP binding

Cellular Component