MIA_03416_1

Protein

Length

437 amino acids

Browser: contig04:1160763-1162077-

Protein function

EGGNOG:	0PG5G	RIB1	GTP cyclohydrolase II
SGD closest match:	S000000129	RIB1	GTP cyclohydrolase-2
CGD closest match:	CAL0000174579	RIB1	GTP cyclohydrolase II

Protein alignments

	%id	Aln length	E-value
MCA_04860_1	72.517%	302	3.70e-159	MCA_04860_1
A0A167CEM0_9ASCO	71.831%	284	1.01e-143	GTP cyclohydrolase II OS=Sugiyamaella lignohabitans GN=RIB1 PE=4 SV=1
UniRef50_A0A167CEM0	71.831%	284	2.77e-140	GTP cyclohydrolase II n=1 Tax=Sugiyamaella lignohabitans TaxID=796027 RepID=A0A167CEM0_9ASCO
A0A060SWF9_BLAAD	73.077%	286	2.57e-148	ARAD1A04290p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1A04290g PE=4 SV=1
A0A1E4TKL0_9ASCO	69.517%	269	3.71e-133	Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_21317 PE=4 SV=1
A0A1E3PK33_9ASCO	58.133%	332	9.10e-128	GTP cyclohydrolase II OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_82745 PE=4 SV=1
Q6C7A9_YARLI	66.312%	282	1.34e-127	YALI0E02288p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E02288g PE=4 SV=1
Q5A1Y2_CANAL	62.021%	287	5.68e-125	GTP cyclohydrolase II OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=RIB1 PE=4 SV=1
RIB1_YEAST	58.596%	285	1.05e-111	GTP cyclohydrolase-2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=RIB1 PE=1 SV=2
A0A0J9XG84_GEOCN	51.748%	286	7.25e-86	Similar to Saccharomyces cerevisiae YBL033C RIB1 GTP cyclohydrolase II OS=Geotrichum candidum GN=BN980_GECA14s02210g PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0020

Protein family membership

GTP cyclohydrolase II, RibA (IPR000926)

Domains and repeats

Domain
176 - 404
GTP cyclohydrolase II (IPR032677)

1 50 100 150 200 250 300 350 400 437

Detailed signature matches

IPR000926

GTP cyclohydrolase II, RibA
1. TIGR00505
  
  227 - 435
  
  TIGRFAMs
  TIGR00505 (TIGR00505)
2. cd00641 (GTP_cycloh...)
  
  176 - 435
  
  CDD
  cd00641 (GTP_cyclohydro2)
IPR032677

GTP cyclohydrolase II
1. SSF142695 (RibA-like)
  
  271 - 404
  
  SUPERFAMILY
  SSF142695 (RibA-like)
  
  176 - 213
  
  SUPERFAMILY
  SSF142695 (RibA-like)
2. PF00925 (GTP_cycloh...)
  
  181 - 403
  
  Pfam
  PF00925 (GTP_cyclohydro2)

no IPR

Unintegrated signatures

mobidb-lite (disord...)

253 - 273

MobiDB Lite
mobidb-lite (disorder_prediction)

1 - 59

MobiDB Lite
mobidb-lite (disorder_prediction)

137 - 163

MobiDB Lite
mobidb-lite (disorder_prediction)

Residue annotation

dimerization inter...

179E

dimerization interface
179E, 180S, 181R, 182A, 183R, 184I, 185P, 194L, 196V, 197Y, 198R, 205E, 207I, 209F, 284E, 286Y, 287T, 289E, 290T, 291A, 292W, 293S, 295R, 302L, 303D, 306A, 319Y, 321R, 329L, 330A, 333L, 334K, 336Y, 337N, 340D
CDD
cd00641 (GTP_cyclohydro2)

180S

dimerization interface
179E, 180S, 181R, 182A, 183R, 184I, 185P, 194L, 196V, 197Y, 198R, 205E, 207I, 209F, 284E, 286Y, 287T, 289E, 290T, 291A, 292W, 293S, 295R, 302L, 303D, 306A, 319Y, 321R, 329L, 330A, 333L, 334K, 336Y, 337N, 340D
CDD
cd00641 (GTP_cyclohydro2)

181R

dimerization interface
179E, 180S, 181R, 182A, 183R, 184I, 185P, 194L, 196V, 197Y, 198R, 205E, 207I, 209F, 284E, 286Y, 287T, 289E, 290T, 291A, 292W, 293S, 295R, 302L, 303D, 306A, 319Y, 321R, 329L, 330A, 333L, 334K, 336Y, 337N, 340D
CDD
cd00641 (GTP_cyclohydro2)

182A

dimerization interface
179E, 180S, 181R, 182A, 183R, 184I, 185P, 194L, 196V, 197Y, 198R, 205E, 207I, 209F, 284E, 286Y, 287T, 289E, 290T, 291A, 292W, 293S, 295R, 302L, 303D, 306A, 319Y, 321R, 329L, 330A, 333L, 334K, 336Y, 337N, 340D
CDD
cd00641 (GTP_cyclohydro2)

183R

dimerization interface
179E, 180S, 181R, 182A, 183R, 184I, 185P, 194L, 196V, 197Y, 198R, 205E, 207I, 209F, 284E, 286Y, 287T, 289E, 290T, 291A, 292W, 293S, 295R, 302L, 303D, 306A, 319Y, 321R, 329L, 330A, 333L, 334K, 336Y, 337N, 340D
CDD
cd00641 (GTP_cyclohydro2)

184I

dimerization interface
179E, 180S, 181R, 182A, 183R, 184I, 185P, 194L, 196V, 197Y, 198R, 205E, 207I, 209F, 284E, 286Y, 287T, 289E, 290T, 291A, 292W, 293S, 295R, 302L, 303D, 306A, 319Y, 321R, 329L, 330A, 333L, 334K, 336Y, 337N, 340D
CDD
cd00641 (GTP_cyclohydro2)

185P

dimerization interface
179E, 180S, 181R, 182A, 183R, 184I, 185P, 194L, 196V, 197Y, 198R, 205E, 207I, 209F, 284E, 286Y, 287T, 289E, 290T, 291A, 292W, 293S, 295R, 302L, 303D, 306A, 319Y, 321R, 329L, 330A, 333L, 334K, 336Y, 337N, 340D
CDD
cd00641 (GTP_cyclohydro2)

194L

dimerization interface
179E, 180S, 181R, 182A, 183R, 184I, 185P, 194L, 196V, 197Y, 198R, 205E, 207I, 209F, 284E, 286Y, 287T, 289E, 290T, 291A, 292W, 293S, 295R, 302L, 303D, 306A, 319Y, 321R, 329L, 330A, 333L, 334K, 336Y, 337N, 340D
CDD
cd00641 (GTP_cyclohydro2)

196V

dimerization interface
179E, 180S, 181R, 182A, 183R, 184I, 185P, 194L, 196V, 197Y, 198R, 205E, 207I, 209F, 284E, 286Y, 287T, 289E, 290T, 291A, 292W, 293S, 295R, 302L, 303D, 306A, 319Y, 321R, 329L, 330A, 333L, 334K, 336Y, 337N, 340D
CDD
cd00641 (GTP_cyclohydro2)

197Y

dimerization interface
179E, 180S, 181R, 182A, 183R, 184I, 185P, 194L, 196V, 197Y, 198R, 205E, 207I, 209F, 284E, 286Y, 287T, 289E, 290T, 291A, 292W, 293S, 295R, 302L, 303D, 306A, 319Y, 321R, 329L, 330A, 333L, 334K, 336Y, 337N, 340D
CDD
cd00641 (GTP_cyclohydro2)

198R

dimerization interface
179E, 180S, 181R, 182A, 183R, 184I, 185P, 194L, 196V, 197Y, 198R, 205E, 207I, 209F, 284E, 286Y, 287T, 289E, 290T, 291A, 292W, 293S, 295R, 302L, 303D, 306A, 319Y, 321R, 329L, 330A, 333L, 334K, 336Y, 337N, 340D
CDD
cd00641 (GTP_cyclohydro2)

205E

dimerization interface
179E, 180S, 181R, 182A, 183R, 184I, 185P, 194L, 196V, 197Y, 198R, 205E, 207I, 209F, 284E, 286Y, 287T, 289E, 290T, 291A, 292W, 293S, 295R, 302L, 303D, 306A, 319Y, 321R, 329L, 330A, 333L, 334K, 336Y, 337N, 340D
CDD
cd00641 (GTP_cyclohydro2)

207I

dimerization interface
179E, 180S, 181R, 182A, 183R, 184I, 185P, 194L, 196V, 197Y, 198R, 205E, 207I, 209F, 284E, 286Y, 287T, 289E, 290T, 291A, 292W, 293S, 295R, 302L, 303D, 306A, 319Y, 321R, 329L, 330A, 333L, 334K, 336Y, 337N, 340D
CDD
cd00641 (GTP_cyclohydro2)

209F

dimerization interface
179E, 180S, 181R, 182A, 183R, 184I, 185P, 194L, 196V, 197Y, 198R, 205E, 207I, 209F, 284E, 286Y, 287T, 289E, 290T, 291A, 292W, 293S, 295R, 302L, 303D, 306A, 319Y, 321R, 329L, 330A, 333L, 334K, 336Y, 337N, 340D
CDD
cd00641 (GTP_cyclohydro2)

284E

dimerization interface
179E, 180S, 181R, 182A, 183R, 184I, 185P, 194L, 196V, 197Y, 198R, 205E, 207I, 209F, 284E, 286Y, 287T, 289E, 290T, 291A, 292W, 293S, 295R, 302L, 303D, 306A, 319Y, 321R, 329L, 330A, 333L, 334K, 336Y, 337N, 340D
CDD
cd00641 (GTP_cyclohydro2)

286Y

dimerization interface
179E, 180S, 181R, 182A, 183R, 184I, 185P, 194L, 196V, 197Y, 198R, 205E, 207I, 209F, 284E, 286Y, 287T, 289E, 290T, 291A, 292W, 293S, 295R, 302L, 303D, 306A, 319Y, 321R, 329L, 330A, 333L, 334K, 336Y, 337N, 340D
CDD
cd00641 (GTP_cyclohydro2)

287T

dimerization interface
179E, 180S, 181R, 182A, 183R, 184I, 185P, 194L, 196V, 197Y, 198R, 205E, 207I, 209F, 284E, 286Y, 287T, 289E, 290T, 291A, 292W, 293S, 295R, 302L, 303D, 306A, 319Y, 321R, 329L, 330A, 333L, 334K, 336Y, 337N, 340D
CDD
cd00641 (GTP_cyclohydro2)

289E

dimerization interface
179E, 180S, 181R, 182A, 183R, 184I, 185P, 194L, 196V, 197Y, 198R, 205E, 207I, 209F, 284E, 286Y, 287T, 289E, 290T, 291A, 292W, 293S, 295R, 302L, 303D, 306A, 319Y, 321R, 329L, 330A, 333L, 334K, 336Y, 337N, 340D
CDD
cd00641 (GTP_cyclohydro2)

290T

dimerization interface
179E, 180S, 181R, 182A, 183R, 184I, 185P, 194L, 196V, 197Y, 198R, 205E, 207I, 209F, 284E, 286Y, 287T, 289E, 290T, 291A, 292W, 293S, 295R, 302L, 303D, 306A, 319Y, 321R, 329L, 330A, 333L, 334K, 336Y, 337N, 340D
CDD
cd00641 (GTP_cyclohydro2)

291A

dimerization interface
179E, 180S, 181R, 182A, 183R, 184I, 185P, 194L, 196V, 197Y, 198R, 205E, 207I, 209F, 284E, 286Y, 287T, 289E, 290T, 291A, 292W, 293S, 295R, 302L, 303D, 306A, 319Y, 321R, 329L, 330A, 333L, 334K, 336Y, 337N, 340D
CDD
cd00641 (GTP_cyclohydro2)

292W

dimerization interface
179E, 180S, 181R, 182A, 183R, 184I, 185P, 194L, 196V, 197Y, 198R, 205E, 207I, 209F, 284E, 286Y, 287T, 289E, 290T, 291A, 292W, 293S, 295R, 302L, 303D, 306A, 319Y, 321R, 329L, 330A, 333L, 334K, 336Y, 337N, 340D
CDD
cd00641 (GTP_cyclohydro2)

293S

dimerization interface
179E, 180S, 181R, 182A, 183R, 184I, 185P, 194L, 196V, 197Y, 198R, 205E, 207I, 209F, 284E, 286Y, 287T, 289E, 290T, 291A, 292W, 293S, 295R, 302L, 303D, 306A, 319Y, 321R, 329L, 330A, 333L, 334K, 336Y, 337N, 340D
CDD
cd00641 (GTP_cyclohydro2)

295R

dimerization interface
179E, 180S, 181R, 182A, 183R, 184I, 185P, 194L, 196V, 197Y, 198R, 205E, 207I, 209F, 284E, 286Y, 287T, 289E, 290T, 291A, 292W, 293S, 295R, 302L, 303D, 306A, 319Y, 321R, 329L, 330A, 333L, 334K, 336Y, 337N, 340D
CDD
cd00641 (GTP_cyclohydro2)

302L

dimerization interface
179E, 180S, 181R, 182A, 183R, 184I, 185P, 194L, 196V, 197Y, 198R, 205E, 207I, 209F, 284E, 286Y, 287T, 289E, 290T, 291A, 292W, 293S, 295R, 302L, 303D, 306A, 319Y, 321R, 329L, 330A, 333L, 334K, 336Y, 337N, 340D
CDD
cd00641 (GTP_cyclohydro2)

303D

dimerization interface
179E, 180S, 181R, 182A, 183R, 184I, 185P, 194L, 196V, 197Y, 198R, 205E, 207I, 209F, 284E, 286Y, 287T, 289E, 290T, 291A, 292W, 293S, 295R, 302L, 303D, 306A, 319Y, 321R, 329L, 330A, 333L, 334K, 336Y, 337N, 340D
CDD
cd00641 (GTP_cyclohydro2)

306A

dimerization interface
179E, 180S, 181R, 182A, 183R, 184I, 185P, 194L, 196V, 197Y, 198R, 205E, 207I, 209F, 284E, 286Y, 287T, 289E, 290T, 291A, 292W, 293S, 295R, 302L, 303D, 306A, 319Y, 321R, 329L, 330A, 333L, 334K, 336Y, 337N, 340D
CDD
cd00641 (GTP_cyclohydro2)

319Y

dimerization interface
179E, 180S, 181R, 182A, 183R, 184I, 185P, 194L, 196V, 197Y, 198R, 205E, 207I, 209F, 284E, 286Y, 287T, 289E, 290T, 291A, 292W, 293S, 295R, 302L, 303D, 306A, 319Y, 321R, 329L, 330A, 333L, 334K, 336Y, 337N, 340D
CDD
cd00641 (GTP_cyclohydro2)

321R

dimerization interface
179E, 180S, 181R, 182A, 183R, 184I, 185P, 194L, 196V, 197Y, 198R, 205E, 207I, 209F, 284E, 286Y, 287T, 289E, 290T, 291A, 292W, 293S, 295R, 302L, 303D, 306A, 319Y, 321R, 329L, 330A, 333L, 334K, 336Y, 337N, 340D
CDD
cd00641 (GTP_cyclohydro2)

329L

dimerization interface
179E, 180S, 181R, 182A, 183R, 184I, 185P, 194L, 196V, 197Y, 198R, 205E, 207I, 209F, 284E, 286Y, 287T, 289E, 290T, 291A, 292W, 293S, 295R, 302L, 303D, 306A, 319Y, 321R, 329L, 330A, 333L, 334K, 336Y, 337N, 340D
CDD
cd00641 (GTP_cyclohydro2)

330A

dimerization interface
179E, 180S, 181R, 182A, 183R, 184I, 185P, 194L, 196V, 197Y, 198R, 205E, 207I, 209F, 284E, 286Y, 287T, 289E, 290T, 291A, 292W, 293S, 295R, 302L, 303D, 306A, 319Y, 321R, 329L, 330A, 333L, 334K, 336Y, 337N, 340D
CDD
cd00641 (GTP_cyclohydro2)

333L

dimerization interface
179E, 180S, 181R, 182A, 183R, 184I, 185P, 194L, 196V, 197Y, 198R, 205E, 207I, 209F, 284E, 286Y, 287T, 289E, 290T, 291A, 292W, 293S, 295R, 302L, 303D, 306A, 319Y, 321R, 329L, 330A, 333L, 334K, 336Y, 337N, 340D
CDD
cd00641 (GTP_cyclohydro2)

334K

dimerization interface
179E, 180S, 181R, 182A, 183R, 184I, 185P, 194L, 196V, 197Y, 198R, 205E, 207I, 209F, 284E, 286Y, 287T, 289E, 290T, 291A, 292W, 293S, 295R, 302L, 303D, 306A, 319Y, 321R, 329L, 330A, 333L, 334K, 336Y, 337N, 340D
CDD
cd00641 (GTP_cyclohydro2)

336Y

dimerization interface
179E, 180S, 181R, 182A, 183R, 184I, 185P, 194L, 196V, 197Y, 198R, 205E, 207I, 209F, 284E, 286Y, 287T, 289E, 290T, 291A, 292W, 293S, 295R, 302L, 303D, 306A, 319Y, 321R, 329L, 330A, 333L, 334K, 336Y, 337N, 340D
CDD
cd00641 (GTP_cyclohydro2)

337N

dimerization interface
179E, 180S, 181R, 182A, 183R, 184I, 185P, 194L, 196V, 197Y, 198R, 205E, 207I, 209F, 284E, 286Y, 287T, 289E, 290T, 291A, 292W, 293S, 295R, 302L, 303D, 306A, 319Y, 321R, 329L, 330A, 333L, 334K, 336Y, 337N, 340D
CDD
cd00641 (GTP_cyclohydro2)

340D

dimerization interface
179E, 180S, 181R, 182A, 183R, 184I, 185P, 194L, 196V, 197Y, 198R, 205E, 207I, 209F, 284E, 286Y, 287T, 289E, 290T, 291A, 292W, 293S, 295R, 302L, 303D, 306A, 319Y, 321R, 329L, 330A, 333L, 334K, 336Y, 337N, 340D
CDD
cd00641 (GTP_cyclohydro2)
active site cd00641

280R

active site
280R, 281I, 282H, 283S, 284E, 285C, 287T, 296C, 298C, 301Q, 322Q, 323E, 324G, 325R, 332K, 336Y, 339Q, 345T, 357D, 359R, 380T, 381N, 382N, 385K
CDD
cd00641 (GTP_cyclohydro2)

281I

active site
280R, 281I, 282H, 283S, 284E, 285C, 287T, 296C, 298C, 301Q, 322Q, 323E, 324G, 325R, 332K, 336Y, 339Q, 345T, 357D, 359R, 380T, 381N, 382N, 385K
CDD
cd00641 (GTP_cyclohydro2)

282H

active site
280R, 281I, 282H, 283S, 284E, 285C, 287T, 296C, 298C, 301Q, 322Q, 323E, 324G, 325R, 332K, 336Y, 339Q, 345T, 357D, 359R, 380T, 381N, 382N, 385K
CDD
cd00641 (GTP_cyclohydro2)

283S

active site
280R, 281I, 282H, 283S, 284E, 285C, 287T, 296C, 298C, 301Q, 322Q, 323E, 324G, 325R, 332K, 336Y, 339Q, 345T, 357D, 359R, 380T, 381N, 382N, 385K
CDD
cd00641 (GTP_cyclohydro2)

284E

active site
280R, 281I, 282H, 283S, 284E, 285C, 287T, 296C, 298C, 301Q, 322Q, 323E, 324G, 325R, 332K, 336Y, 339Q, 345T, 357D, 359R, 380T, 381N, 382N, 385K
CDD
cd00641 (GTP_cyclohydro2)

285C

active site
280R, 281I, 282H, 283S, 284E, 285C, 287T, 296C, 298C, 301Q, 322Q, 323E, 324G, 325R, 332K, 336Y, 339Q, 345T, 357D, 359R, 380T, 381N, 382N, 385K
CDD
cd00641 (GTP_cyclohydro2)

287T

active site
280R, 281I, 282H, 283S, 284E, 285C, 287T, 296C, 298C, 301Q, 322Q, 323E, 324G, 325R, 332K, 336Y, 339Q, 345T, 357D, 359R, 380T, 381N, 382N, 385K
CDD
cd00641 (GTP_cyclohydro2)

296C

active site
280R, 281I, 282H, 283S, 284E, 285C, 287T, 296C, 298C, 301Q, 322Q, 323E, 324G, 325R, 332K, 336Y, 339Q, 345T, 357D, 359R, 380T, 381N, 382N, 385K
CDD
cd00641 (GTP_cyclohydro2)

298C

active site
280R, 281I, 282H, 283S, 284E, 285C, 287T, 296C, 298C, 301Q, 322Q, 323E, 324G, 325R, 332K, 336Y, 339Q, 345T, 357D, 359R, 380T, 381N, 382N, 385K
CDD
cd00641 (GTP_cyclohydro2)

301Q

active site
280R, 281I, 282H, 283S, 284E, 285C, 287T, 296C, 298C, 301Q, 322Q, 323E, 324G, 325R, 332K, 336Y, 339Q, 345T, 357D, 359R, 380T, 381N, 382N, 385K
CDD
cd00641 (GTP_cyclohydro2)

322Q

active site
280R, 281I, 282H, 283S, 284E, 285C, 287T, 296C, 298C, 301Q, 322Q, 323E, 324G, 325R, 332K, 336Y, 339Q, 345T, 357D, 359R, 380T, 381N, 382N, 385K
CDD
cd00641 (GTP_cyclohydro2)

323E

active site
280R, 281I, 282H, 283S, 284E, 285C, 287T, 296C, 298C, 301Q, 322Q, 323E, 324G, 325R, 332K, 336Y, 339Q, 345T, 357D, 359R, 380T, 381N, 382N, 385K
CDD
cd00641 (GTP_cyclohydro2)

324G

active site
280R, 281I, 282H, 283S, 284E, 285C, 287T, 296C, 298C, 301Q, 322Q, 323E, 324G, 325R, 332K, 336Y, 339Q, 345T, 357D, 359R, 380T, 381N, 382N, 385K
CDD
cd00641 (GTP_cyclohydro2)

325R

active site
280R, 281I, 282H, 283S, 284E, 285C, 287T, 296C, 298C, 301Q, 322Q, 323E, 324G, 325R, 332K, 336Y, 339Q, 345T, 357D, 359R, 380T, 381N, 382N, 385K
CDD
cd00641 (GTP_cyclohydro2)

332K

active site
280R, 281I, 282H, 283S, 284E, 285C, 287T, 296C, 298C, 301Q, 322Q, 323E, 324G, 325R, 332K, 336Y, 339Q, 345T, 357D, 359R, 380T, 381N, 382N, 385K
CDD
cd00641 (GTP_cyclohydro2)

336Y

active site
280R, 281I, 282H, 283S, 284E, 285C, 287T, 296C, 298C, 301Q, 322Q, 323E, 324G, 325R, 332K, 336Y, 339Q, 345T, 357D, 359R, 380T, 381N, 382N, 385K
CDD
cd00641 (GTP_cyclohydro2)

339Q

active site
280R, 281I, 282H, 283S, 284E, 285C, 287T, 296C, 298C, 301Q, 322Q, 323E, 324G, 325R, 332K, 336Y, 339Q, 345T, 357D, 359R, 380T, 381N, 382N, 385K
CDD
cd00641 (GTP_cyclohydro2)

345T

active site
280R, 281I, 282H, 283S, 284E, 285C, 287T, 296C, 298C, 301Q, 322Q, 323E, 324G, 325R, 332K, 336Y, 339Q, 345T, 357D, 359R, 380T, 381N, 382N, 385K
CDD
cd00641 (GTP_cyclohydro2)

357D

active site
280R, 281I, 282H, 283S, 284E, 285C, 287T, 296C, 298C, 301Q, 322Q, 323E, 324G, 325R, 332K, 336Y, 339Q, 345T, 357D, 359R, 380T, 381N, 382N, 385K
CDD
cd00641 (GTP_cyclohydro2)

359R

active site
280R, 281I, 282H, 283S, 284E, 285C, 287T, 296C, 298C, 301Q, 322Q, 323E, 324G, 325R, 332K, 336Y, 339Q, 345T, 357D, 359R, 380T, 381N, 382N, 385K
CDD
cd00641 (GTP_cyclohydro2)

380T

active site
280R, 281I, 282H, 283S, 284E, 285C, 287T, 296C, 298C, 301Q, 322Q, 323E, 324G, 325R, 332K, 336Y, 339Q, 345T, 357D, 359R, 380T, 381N, 382N, 385K
CDD
cd00641 (GTP_cyclohydro2)

381N

active site
280R, 281I, 282H, 283S, 284E, 285C, 287T, 296C, 298C, 301Q, 322Q, 323E, 324G, 325R, 332K, 336Y, 339Q, 345T, 357D, 359R, 380T, 381N, 382N, 385K
CDD
cd00641 (GTP_cyclohydro2)

382N

active site
280R, 281I, 282H, 283S, 284E, 285C, 287T, 296C, 298C, 301Q, 322Q, 323E, 324G, 325R, 332K, 336Y, 339Q, 345T, 357D, 359R, 380T, 381N, 382N, 385K
CDD
cd00641 (GTP_cyclohydro2)

385K

active site
280R, 281I, 282H, 283S, 284E, 285C, 287T, 296C, 298C, 301Q, 322Q, 323E, 324G, 325R, 332K, 336Y, 339Q, 345T, 357D, 359R, 380T, 381N, 382N, 385K
CDD
cd00641 (GTP_cyclohydro2)

Protein sequence

>MIA_03416_1
MSSNNSPNQTPSNTTHPSTLQPGSSDAVALSASCSSLSSTSSSNLSLVSPSSSTSSFSDFSMSLISPAPTPSPDDVKKQQ
AAGSAPASAVVSAPTGAFLSNLVGGPAAAATAAPVAVLAEQSPLSFTAGNLSTTLKTLNNSGPAQRASQAPLPQPSATQK
QSAIASIQLDDTLPIVVCESRARIPLTTGGEIFLHVYRNNVDTKEHIAFVFGDRIRSKSLFAERPGETEEDRMVRGAYDG
TLFPGRQVSKIVDSPSKTCPHHKNTTASTTSTHRKDTLVRIHSECYTGETAWSARCDCGEQLDEAARVMAQEGEGVIVYL
RQEGRGIGLAEKLKAYNLQDLGADTVTANLMLRHPADARSFGLATAILLDLGLHDVRLMTNNPDKIRAVEGKNHEIHVTE
RVPMVPLSWQNKGGFQSKEVDQYLKTKIERMGHMIHE

GO term prediction

Biological Process

GO:0009231 riboflavin biosynthetic process

Molecular Function

GO:0003935 GTP cyclohydrolase II activity

Cellular Component

None predicted.

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Entry type

Status

Per-residue features