Protein
MCA_04860_1
Length
422 amino acids
Gene name: RIB1
Description: GTP cyclohydrolase-2
Browser: contigC:4281617-4282886-
RNA-seq: read pairs 2498, FPKM 73.0, percentile rank 73.5% (100% = highest expression)
Protein function
| Annotation: | RIB1 | GTP cyclohydrolase-2 | |
|---|---|---|---|
| KEGG: | K01497 | ribA | GTP cyclohydrolase II [EC:3.5.4.25] |
| EGGNOG: | 0PG5G | RIB1 | GTP cyclohydrolase II |
| SGD closest match: | S000000129 | RIB1 | GTP cyclohydrolase-2 |
| CGD closest match: | CAL0000174579 | RIB1 | GTP cyclohydrolase II |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MIA_03416_1 | 61.70% | 376 | 9e-156 | MIA_03416_1 |
| A0A167CEM0_9ASCO | 70.94% | 265 | 2e-135 | GTP cyclohydrolase II OS=Sugiyamaella lignohabitans GN=RIB1 PE=4 SV=1 |
| UniRef50_A0A167CEM0 | 70.94% | 265 | 4e-132 | GTP cyclohydrolase II n=1 Tax=Sugiyamaella lignohabitans TaxID=796027 RepID=A0A167CEM0_9ASCO |
| A0A060SWF9_BLAAD | 69.57% | 276 | 3e-139 | ARAD1A04290p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1A04290g PE=4 SV=1 |
| A0A1E4TKL0_9ASCO | 67.79% | 267 | 4e-126 | Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_21317 PE=4 SV=1 |
| Q5A1Y2_CANAL | 64.10% | 273 | 2e-118 | GTP cyclohydrolase II OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=RIB1 PE=4 SV=1 |
| Q6C7A9_YARLI | 60.33% | 305 | 9e-119 | YALI0E02288p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E02288g PE=4 SV=1 |
| A0A1E3PK33_9ASCO | 61.22% | 294 | 4e-117 | GTP cyclohydrolase II OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_82745 PE=4 SV=1 |
| RIB1_YEAST | 57.60% | 283 | 7e-104 | GTP cyclohydrolase-2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=RIB1 PE=1 SV=2 |
| A0A0J9XG84_GEOCN | 47.83% | 299 | 4e-78 | Similar to Saccharomyces cerevisiae YBL033C RIB1 GTP cyclohydrolase II OS=Geotrichum candidum GN=BN980_GECA14s02210g PE=4 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.1932
Protein family membership
- GTP cyclohydrolase II, RibA (IPR000926)
Domains and repeats
-
Domain
1
50
100
150
200
250
300
350
422
Detailed signature matches
no IPR
Unintegrated signatures
-
mobidb-lite (disord...)
Residue annotation
-
dimerization inter...
-
active site cd00641
Protein sequence
>MCA_04860_1 MTTFSSSSSSPSFSSTNLSSKFDQHHHHPYCSHSFTSTNSSSSSSPLITTKSSDSDESSVVSASSSSTSLNTYQQSSTPM SIISPAPSPRPDETVDALKRTRGIQAANIINSLVGPTHTSNSQLTLESLNALNSSGPVSRASSQDDAESNKIKVDDVLPE VYCESRARIPITSGGYIFLHVYKNNVDNKEHIAFVFNEKIHSKSLFAPRPNETEQDRMIRGAYDGFLYPGRDKSTLDDEQ QKQEKNNNTTNQDPNEDVLVRIHSECYTGETAWSARCDCGEQLEEAAKIMGEIGNGVIVYLRQEGRGIGLAEKLKAYNLQ DLGADTVTANLMLKHPADARSFGLATAILLDLGLHNIKLMTNNPDKIRAVEGKNKEIHVSQRVPMVPLSWQDKGGFTSKE VDQYLKTKIERMGHMIEIVHPN
GO term prediction
Biological Process
GO:0009231 riboflavin biosynthetic process
Molecular Function
GO:0003935 GTP cyclohydrolase II activity
Cellular Component
None predicted.