Protein

MIA_03351_1

Length
509 amino acids


Browser: contig04:963587-965117+

Protein function

EGGNOG:0PGPSPGUG_02594mitochondrial DnaJ chaperone
SGD closest match:S000001878MDJ1DnaJ homolog 1, mitochondrial
CGD closest match:CAL0000175831MDJ1Mdj1p

Protein alignments

%idAln lengthE-value
MCA_02903_156.064%5033.94e-164MCA_02903_1
A0A0J9YHB8_GEOCN55.579%4842.64e-161Similar to Saccharomyces cerevisiae YFL016C MDJ1 Co-chaperone that stimulates the ATPase activity of the HSP70 protein Ssc1p OS=Geotrichum candidum GN=BN980_GECA01s02111g PE=3 SV=1
A0A060T8E9_BLAAD47.708%4808.45e-128ARAD1C36476p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C36476g PE=3 SV=1
A0A1E3PEV8_9ASCO45.963%4833.84e-118DnaJ-domain-containing protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_48072 PE=3 SV=1
A0A1E4TCF3_9ASCO48.558%4162.65e-112Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_4016 PE=3 SV=1
UniRef50_A0A1E4TCF348.558%4169.30e-109Uncharacterized protein n=1 Tax=Tortispora caseinolytica NRRL Y-17796 TaxID=767744 RepID=A0A1E4TCF3_9ASCO
A0A167DK99_9ASCO53.125%3202.88e-111Mdj1p OS=Sugiyamaella lignohabitans GN=MDJ1 PE=3 SV=1
A0A1D8PNQ8_CANAL43.191%4702.39e-102Mdj1p OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=MDJ1 PE=3 SV=1
Q6C1X9_YARLI45.955%3091.64e-77YALI0F12551p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F12551g PE=3 SV=1
MDJ1_YEAST36.533%3233.24e-59DnaJ homolog 1, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=MDJ1 PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.9926
Predicted cleavage: 50

Protein family membership

Domains and repeats

  1. Domain
  2. Domain
  3. Domain
1 50 100 150 200 250 300 350 400 450 509

Detailed signature matches

    1. MF_01152 (DnaJ)
    1. SM00271 (dnaj_3)
    2. PF00226 (DnaJ)
    3. PS50076 (DNAJ_2)
    4. SSF46565 (Chaperone...)
    5. cd06257 (DnaJ)
    6. PR00625 (JDOMAIN)
    1. SSF49493 (HSP40/Dna...)
    1. PF01556 (DnaJ_C)
    1. PS51188 (ZF_CR)
    2. SSF57938 (DnaJ/Hsp4...)
    3. cd10719 (DnaJ_zf)
    4. PF00684 (DnaJ_CXXCXGXG)
    1. PS00636 (DNAJ_1)
Unintegrated signatures no IPR
Unintegrated signatures
  1. cd10747 (DnaJ_C)
  2. mobidb-lite (disord...)

Residue annotation

  1. HSP70 interaction ...
  2. substrate binding ...
  3. Zn binding sites c...
  4. dimer interface cd...

Protein sequence

>MIA_03351_1
MYSRPSLASALLRRGSSALRPKRILHPARPLRSSPPAFVRPFHASAQSLFKDPYKVLGVSNSASAGEIKKAYYQLAKKYH
PDVNKESGADEKFQDIQSAYEILSDADQKAKYDQFGAAAFDQSAGAGSHPGAGFGADGPFNPFGGFGFGGGAAGGGAGPF
SFHDIFNDAFGRGRTGGGAGGRGATRERMAYKGDDIEMATTISLEDVAHGTSKSISYSTVDDCGTCHGSGMKPGEKRKTC
PSCHGTGTAMHVIQGGFQMASTCGTCGGSGVVIPKSAECGTCHAHGVVNNTRTVTIDIPAGIQDGARLRVAGGGDAPEVL
ADADVHRIRGDLYVRIKVAPHKVFQRSKSDLLYTTTVPFTTAALGGTIEVPMLDNKKIRLKIPQGAQSGMVITVNGAGLP
VAGRKNSAKGDYKVSVNVNILKPTTATQTALLEALADAFGDNTARRVSPSWKPEPTPDSGAPGAADAQPTDAQSSESSNS
CEHPGFLKKLFNLVTQAHEKDQKAKKENQ

GO term prediction

Biological Process

GO:0006457 protein folding
GO:0009408 response to heat

Molecular Function

GO:0005524 ATP binding
GO:0031072 heat shock protein binding
GO:0051082 unfolded protein binding

Cellular Component

None predicted.