Protein

MCA_02903_1

Length
565 amino acids


Gene name: MDJ1

Description: DnaJ homolog 1, mitochondrial

Browser: contigB:2699188-2700886-

RNA-seq: read pairs 2942, FPKM 64.2, percentile rank 70.6% (100% = highest expression)

Protein function

Annotation:MDJ1DnaJ homolog 1, mitochondrial
KEGG:K03686dnaJ molecular chaperone DnaJ
EGGNOG:0PGPSPGUG_02594mitochondrial DnaJ chaperone
SGD closest match:S000001878MDJ1DnaJ homolog 1, mitochondrial
CGD closest match:CAL0000175831MDJ1Mdj1p

Protein alignments

%idAln lengthE-value
MIA_03351_152.49%5031e-155MIA_03351_1
A0A0J9YHB8_GEOCN49.28%3451e-111Similar to Saccharomyces cerevisiae YFL016C MDJ1 Co-chaperone that stimulates the ATPase activity of the HSP70 protein Ssc1p OS=Geotrichum candidum GN=BN980_GECA01s02111g PE=3 SV=1
A0A167DK99_9ASCO50.45%3371e-109Mdj1p OS=Sugiyamaella lignohabitans GN=MDJ1 PE=3 SV=1
UniRef50_A0A167DK9950.45%3374e-106Mdj1p n=5 Tax=Saccharomycetales TaxID=4892 RepID=A0A167DK99_9ASCO
A0A060T8E9_BLAAD46.65%3433e-96ARAD1C36476p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C36476g PE=3 SV=1
A0A1E4TCF3_9ASCO48.56%2788e-82Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_4016 PE=3 SV=1
A0A1E3PEV8_9ASCO41.19%3692e-80DnaJ-domain-containing protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_48072 PE=3 SV=1
A0A1D8PNQ8_CANAL43.75%2721e-70Mdj1p OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=MDJ1 PE=3 SV=1
Q6C1X9_YARLI41.73%2786e-67YALI0F12551p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F12551g PE=3 SV=1
MDJ1_YEAST37.82%2752e-55DnaJ homolog 1, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=MDJ1 PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.9960
Predicted cleavage: 77

Protein family membership

Domains and repeats

  1. Domain
  2. Domain
  3. Domain
1 100 200 300 400 500 565

Detailed signature matches

    1. MF_01152 (DnaJ)
    1. SM00271 (dnaj_3)
    2. PF00226 (DnaJ)
    3. PS50076 (DNAJ_2)
    4. SSF46565 (Chaperone...)
    5. cd06257 (DnaJ)
    6. PR00625 (JDOMAIN)
    1. SSF49493 (HSP40/Dna...)
    1. PF01556 (DnaJ_C)
    1. PS51188 (ZF_CR)
    2. SSF57938 (DnaJ/Hsp4...)
    3. cd10719 (DnaJ_zf)
    4. PF00684 (DnaJ_CXXCXGXG)
    1. PS00636 (DNAJ_1)
Unintegrated signatures no IPR
Unintegrated signatures
  1. cd10747 (DnaJ_C)
  2. mobidb-lite (disord...)

Residue annotation

  1. HSP70 interaction ...
  2. substrate binding ...
  3. Zn binding sites c...
  4. dimer interface cd...

Protein sequence

>MCA_02903_1
MIFSPRSSTAIYRTVLRASKRSFTRSLFNIHGSRERGLKVTNNNGFIYSNVNTQPTFASSSGKIARRHFRSSALAQAMKD
PYKVLGVSKNASAKEIKKAYYQLAKKYHPDVNKEKDADEKFQDIQSSYEILSDADKKAKYDQFGAAAFDPSAGGGGPGGA
GGPGGFGGFGGGDGFNPFSNFGFGFGGGGQSGDFSFHDIFGDSFGNRGRGRGSAREQMTYRGDDIEIQTSITLEEVAAGT
SKTIHFSTLDECDSCHGSGLKEGKTRKTCPSCNGSGTMVHQVQGGFHLASTCTTCGGSGVIIPKSSECDTCHSRGVVNHA
QSRVVDIPAGVEDGVRLRMVGCGDSPEVLAESNVKRIKGDLYVRVRVQPHPIFTRINGHDLSYTAKVPFTTAALGGKILV
PVLDKSGKKFTSIENSSKVRIRIPPGTQSGTVISIADRGLPITRRSGHVRHGDYKVNINVEIMKPTTATQIALLEALADS
FNDTTANRETVTWKPEPTEFKLNLDEDTKTGAKSDEKNASTESKDSSETSNDTESSSHGSMSSFLKNLFSKITHAQEKDK
KAGKS

GO term prediction

Biological Process

GO:0006457 protein folding
GO:0009408 response to heat

Molecular Function

GO:0005524 ATP binding
GO:0031072 heat shock protein binding
GO:0051082 unfolded protein binding

Cellular Component

None predicted.