Protein

MIA_03343_1

Length
704 amino acids


Browser: contig04:945636-948186-

Protein function

EGGNOG:0PFW3ILV2Acetolactate synthase
SGD closest match:S000004714ILV2Acetolactate synthase catalytic subunit, mitochondrial
CGD closest match:CAL0000198378ILV2Acetolactate synthase

Protein alignments

%idAln lengthE-value
MCA_03747_188.779%6060.0MCA_03747_1
A0A0J9XDD8_GEOCN85.473%5920.0Acetolactate synthase OS=Geotrichum candidum GN=BN980_GECA11s00197g PE=3 SV=1
A0A167CYS7_9ASCO78.498%5860.0Acetolactate synthase OS=Sugiyamaella lignohabitans GN=ILV2 PE=3 SV=1
A0A060T3D1_BLAAD75.926%5940.0Acetolactate synthase OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C36410g PE=3 SV=1
Q6CDI5_YARLI73.058%6050.0Acetolactate synthase OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_C00253g PE=3 SV=1
A0A1E3PEA0_9ASCO72.772%6060.0Acetolactate synthase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_48073 PE=3 SV=1
A0A1E4TAW9_9ASCO71.843%5860.0Acetolactate synthase OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_32297 PE=3 SV=1
A0A1D8PJF9_CANAL71.331%5860.0Acetolactate synthase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=ILV2 PE=3 SV=1
UniRef50_A0A1E3QVR072.635%5920.0Acetolactate synthase n=1 Tax=Babjeviella inositovora NRRL Y-12698 TaxID=984486 RepID=A0A1E3QVR0_9ASCO
ILVB_YEAST69.113%5860.0Acetolactate synthase catalytic subunit, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ILV2 PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.9996
Predicted cleavage: 59

Protein family membership

Domains and repeats

1 100 200 300 400 500 600 704

Detailed signature matches

    1. SSF52518 (Thiamin d...)
    1. PF02776 (TPP_enzyme_N)
    1. SSF52467 (DHS-like ...)
    1. PF00205 (TPP_enzyme_M)
    1. PF02775 (TPP_enzyme_C)
    1. PS00187 (TPP_ENZYMES)
Unintegrated signatures no IPR
Unintegrated signatures
  1. cd02015 (TPP_AHAS)
  2. cd07035 (TPP_PYR_PO...)
  3. mobidb-lite (disord...)

Residue annotation

  1. PYR/PP interface c...
  2. TPP binding site c...
  3. dimer interface cd...
  4. TPP-binding site c...
  5. dimer interface cd...

Protein sequence

>MIA_03343_1
MLRTTSARALRPIIARRAFVSANRFAAVPALTRCISSTSNKKSSSAAATATAPSAARPEPAPSFNTVEGPTEGVRVNSPN
TAMDDSFIGLTGGQIFHEMMLRHNVDTVFGYSGGAILPVFDGIYNSPHFKFIMPRHEQGAGHMAEGYAKATGKPGVVIVT
SGPGATNVVTPMQDALSDGIPMVVFTGQVSTAAIGTDAFQEADVVGISRSCTKWNVMVKNIAELPRRINEAFEIATSGRP
GPVLVDLPKDVTSAVLRDAIPTASTIPSQSIQNLAASAVSEFQSESIQRAADLINKAKKPILYVGNGIMNSEEGPVLLRQ
LAHKAQIPVTTTLHGLGAFDETDDKALRMLGMHGAGYANMAMQNADVIIALGARFDERVTGNIAKFAPAARLAALEKRGG
IVHFEILPKNINKVVEATEAVEGDVSQNLAKLLPLIETVKERPEWLGQVAEWKAKYPFDYERDVPGSGEPVKPQTVITKL
SELCEPIKDKVIMTTGVGQHQMWAAQFFKFKYPRSMISSGGLGTMGFGLPAAIGAKAGSPDAIVIDIDGDASFNMTLAEL
SCAVQYGINVKIVVLNNEEQGMVTQWQSLFYDDRYAHTHQKNPDFMKLAEAMGLKGIRIHNYEELEGGLKEMLDYNQGPV
LVEVIVDQKVPVLPMIAAGKGLDEFLVYNKEVELERKKLRRERAERNRKKAEAAAAAWESNANK

GO term prediction

Biological Process

GO:0009082 branched-chain amino acid biosynthetic process

Molecular Function

GO:0000287 magnesium ion binding
GO:0003824 catalytic activity
GO:0003984 acetolactate synthase activity
GO:0030976 thiamine pyrophosphate binding
GO:0050660 flavin adenine dinucleotide binding

Cellular Component

None predicted.