MIA_03334_1

Protein

Length

662 amino acids

Protein function

EGGNOG:	0PGXP	ACS1	Acetate-CoA ligase
SGD closest match:	S000004143	ACS2	Acetyl-coenzyme A synthetase 2
CGD closest match:	CAL0000197968	ACS2	Acetyl-coenzyme A synthetase 2

Protein alignments

	%id	Aln length
A0A0J9XF58_GEOCN	88.208%	653	Acetyl-coenzyme A synthetase OS=Geotrichum candidum GN=BN980_GECA14s00384g PE=3 SV=1
MCA_01525_1	86.870%	655	MCA_01525_1
A0A1E3PTR0_9ASCO	77.679%	672	Acetyl-coenzyme A synthetase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_40027 PE=3 SV=1
A0A167BYL8_9ASCO	77.259%	642	Acetyl-coenzyme A synthetase OS=Sugiyamaella lignohabitans GN=ACS2 PE=3 SV=1
A0A060SX34_BLAAD	72.239%	652	Acetyl-coenzyme A synthetase OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1A05764g PE=3 SV=1
Q6C2Q5_YARLI	72.473%	643	Acetyl-coenzyme A synthetase OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F05962g PE=3 SV=1
A0A1E4TAC1_9ASCO	70.615%	650	Acetyl-coenzyme A synthetase OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_3299 PE=3 SV=1
UniRef50_G0RZW2	71.900%	637	Acetyl-coenzyme A synthetase-like protein n=1 Tax=Chaetomium thermophilum (strain DSM 1495 / CBS 144.50 / IMI 039719) TaxID=759272 RepID=G0RZW2_CHATD
ACS2_CANAL	69.313%	655	Acetyl-coenzyme A synthetase 2 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=ACS2 PE=3 SV=3
ACS2_YEAST	65.361%	664	Acetyl-coenzyme A synthetase 2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ACS2 PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0352

Protein family membership

Acetate-CoA ligase (IPR011904)

Domains and repeats

Domain
34 - 90
Acetyl-coenzyme A synthetase, N-terminal domain (IPR032387)
92 - 531
AMP-dependent synthetase/ligase (IPR000873)
540 - 618
AMP-binding enzyme, C-terminal domain (IPR025110)

1 100 200 300 400 500 600 662

Detailed signature matches

IPR011904

Acetate-CoA ligase
1. cd05966 (ACS)
  
  38 - 643
  
  CDD
  cd05966 (ACS)
2. TIGR02188
  
  29 - 652
  
  TIGRFAMs
  TIGR02188 (TIGR02188)
IPR032387

Acetyl-coenzyme A synthetase, N-terminal domain
1. PF16177 (ACAS_N)
  
  34 - 90
  
  Pfam
  PF16177 (ACAS_N)
IPR000873

AMP-dependent synthetase/ligase
1. PF00501 (AMP-binding)
  
  92 - 531
  
  Pfam
  PF00501 (AMP-binding)
IPR025110

AMP-binding enzyme, C-terminal domain
1. PF13193 (AMP-binding_C)
  
  540 - 618
  
  Pfam
  PF13193 (AMP-binding_C)
IPR020845

AMP-binding, conserved site
1. PS00455 (AMP_BINDING)
  
  268 - 279
  
  PROSITE patterns
  PS00455 (AMP_BINDING)

no IPR

Unintegrated signatures

G3DSA:2.30.38.10

434 - 524

GENE3D
G3DSA:2.30.38.10 (G3DSA:2.30.38.10)
G3DSA:3.30.30...

527 - 659

GENE3D
G3DSA:3.30.300.30 (G3DSA:3.30.300.30)
G3DSA:3.40.50...

274 - 433

GENE3D
G3DSA:3.40.50.980 (G3DSA:3.40.50.980)

83 - 273

GENE3D
G3DSA:3.40.50.980 (G3DSA:3.40.50.980)
SSF56801 (Acetyl-Co...)

33 - 648

SUPERFAMILY
SSF56801 (Acetyl-CoA synthetase-like)
mobidb-lite (disord...)

1 - 25

MobiDB Lite
mobidb-lite (disorder_prediction)

Residue annotation

CoA binding site c...

172F

CoA binding site
172F, 173A, 174G, 200R, 203K, 205V, 312G, 318T, 340T, 341P, 342A, 366T, 367A, 370L, 532S, 533G, 534H, 593R, 598P
CDD
cd05966 (ACS)

173A

CoA binding site
172F, 173A, 174G, 200R, 203K, 205V, 312G, 318T, 340T, 341P, 342A, 366T, 367A, 370L, 532S, 533G, 534H, 593R, 598P
CDD
cd05966 (ACS)

174G

CoA binding site
172F, 173A, 174G, 200R, 203K, 205V, 312G, 318T, 340T, 341P, 342A, 366T, 367A, 370L, 532S, 533G, 534H, 593R, 598P
CDD
cd05966 (ACS)

200R

CoA binding site
172F, 173A, 174G, 200R, 203K, 205V, 312G, 318T, 340T, 341P, 342A, 366T, 367A, 370L, 532S, 533G, 534H, 593R, 598P
CDD
cd05966 (ACS)

203K

CoA binding site
172F, 173A, 174G, 200R, 203K, 205V, 312G, 318T, 340T, 341P, 342A, 366T, 367A, 370L, 532S, 533G, 534H, 593R, 598P
CDD
cd05966 (ACS)

205V

CoA binding site
172F, 173A, 174G, 200R, 203K, 205V, 312G, 318T, 340T, 341P, 342A, 366T, 367A, 370L, 532S, 533G, 534H, 593R, 598P
CDD
cd05966 (ACS)

312G

CoA binding site
172F, 173A, 174G, 200R, 203K, 205V, 312G, 318T, 340T, 341P, 342A, 366T, 367A, 370L, 532S, 533G, 534H, 593R, 598P
CDD
cd05966 (ACS)

318T

CoA binding site
172F, 173A, 174G, 200R, 203K, 205V, 312G, 318T, 340T, 341P, 342A, 366T, 367A, 370L, 532S, 533G, 534H, 593R, 598P
CDD
cd05966 (ACS)

340T

CoA binding site
172F, 173A, 174G, 200R, 203K, 205V, 312G, 318T, 340T, 341P, 342A, 366T, 367A, 370L, 532S, 533G, 534H, 593R, 598P
CDD
cd05966 (ACS)

341P

CoA binding site
172F, 173A, 174G, 200R, 203K, 205V, 312G, 318T, 340T, 341P, 342A, 366T, 367A, 370L, 532S, 533G, 534H, 593R, 598P
CDD
cd05966 (ACS)

342A

CoA binding site
172F, 173A, 174G, 200R, 203K, 205V, 312G, 318T, 340T, 341P, 342A, 366T, 367A, 370L, 532S, 533G, 534H, 593R, 598P
CDD
cd05966 (ACS)

366T

CoA binding site
172F, 173A, 174G, 200R, 203K, 205V, 312G, 318T, 340T, 341P, 342A, 366T, 367A, 370L, 532S, 533G, 534H, 593R, 598P
CDD
cd05966 (ACS)

367A

CoA binding site
172F, 173A, 174G, 200R, 203K, 205V, 312G, 318T, 340T, 341P, 342A, 366T, 367A, 370L, 532S, 533G, 534H, 593R, 598P
CDD
cd05966 (ACS)

370L

CoA binding site
172F, 173A, 174G, 200R, 203K, 205V, 312G, 318T, 340T, 341P, 342A, 366T, 367A, 370L, 532S, 533G, 534H, 593R, 598P
CDD
cd05966 (ACS)

532S

CoA binding site
172F, 173A, 174G, 200R, 203K, 205V, 312G, 318T, 340T, 341P, 342A, 366T, 367A, 370L, 532S, 533G, 534H, 593R, 598P
CDD
cd05966 (ACS)

533G

CoA binding site
172F, 173A, 174G, 200R, 203K, 205V, 312G, 318T, 340T, 341P, 342A, 366T, 367A, 370L, 532S, 533G, 534H, 593R, 598P
CDD
cd05966 (ACS)

534H

CoA binding site
172F, 173A, 174G, 200R, 203K, 205V, 312G, 318T, 340T, 341P, 342A, 366T, 367A, 370L, 532S, 533G, 534H, 593R, 598P
CDD
cd05966 (ACS)

593R

CoA binding site
172F, 173A, 174G, 200R, 203K, 205V, 312G, 318T, 340T, 341P, 342A, 366T, 367A, 370L, 532S, 533G, 534H, 593R, 598P
CDD
cd05966 (ACS)

598P

CoA binding site
172F, 173A, 174G, 200R, 203K, 205V, 312G, 318T, 340T, 341P, 342A, 366T, 367A, 370L, 532S, 533G, 534H, 593R, 598P
CDD
cd05966 (ACS)
active site cd05966

172F

active site
172F, 173A, 174G, 200R, 203K, 205V, 312G, 317I, 318T, 340T, 341P, 342A, 366T, 367A, 370L, 393V, 394G, 395E, 396P, 418D, 419T, 420Y, 421W, 422Q, 423T, 509D, 521I, 524R, 532S, 533G, 534H, 535R, 593R, 598P, 599F
CDD
cd05966 (ACS)

173A

active site
172F, 173A, 174G, 200R, 203K, 205V, 312G, 317I, 318T, 340T, 341P, 342A, 366T, 367A, 370L, 393V, 394G, 395E, 396P, 418D, 419T, 420Y, 421W, 422Q, 423T, 509D, 521I, 524R, 532S, 533G, 534H, 535R, 593R, 598P, 599F
CDD
cd05966 (ACS)

174G

active site
172F, 173A, 174G, 200R, 203K, 205V, 312G, 317I, 318T, 340T, 341P, 342A, 366T, 367A, 370L, 393V, 394G, 395E, 396P, 418D, 419T, 420Y, 421W, 422Q, 423T, 509D, 521I, 524R, 532S, 533G, 534H, 535R, 593R, 598P, 599F
CDD
cd05966 (ACS)

200R

active site
172F, 173A, 174G, 200R, 203K, 205V, 312G, 317I, 318T, 340T, 341P, 342A, 366T, 367A, 370L, 393V, 394G, 395E, 396P, 418D, 419T, 420Y, 421W, 422Q, 423T, 509D, 521I, 524R, 532S, 533G, 534H, 535R, 593R, 598P, 599F
CDD
cd05966 (ACS)

203K

active site
172F, 173A, 174G, 200R, 203K, 205V, 312G, 317I, 318T, 340T, 341P, 342A, 366T, 367A, 370L, 393V, 394G, 395E, 396P, 418D, 419T, 420Y, 421W, 422Q, 423T, 509D, 521I, 524R, 532S, 533G, 534H, 535R, 593R, 598P, 599F
CDD
cd05966 (ACS)

205V

active site
172F, 173A, 174G, 200R, 203K, 205V, 312G, 317I, 318T, 340T, 341P, 342A, 366T, 367A, 370L, 393V, 394G, 395E, 396P, 418D, 419T, 420Y, 421W, 422Q, 423T, 509D, 521I, 524R, 532S, 533G, 534H, 535R, 593R, 598P, 599F
CDD
cd05966 (ACS)

312G

active site
172F, 173A, 174G, 200R, 203K, 205V, 312G, 317I, 318T, 340T, 341P, 342A, 366T, 367A, 370L, 393V, 394G, 395E, 396P, 418D, 419T, 420Y, 421W, 422Q, 423T, 509D, 521I, 524R, 532S, 533G, 534H, 535R, 593R, 598P, 599F
CDD
cd05966 (ACS)

317I

active site
172F, 173A, 174G, 200R, 203K, 205V, 312G, 317I, 318T, 340T, 341P, 342A, 366T, 367A, 370L, 393V, 394G, 395E, 396P, 418D, 419T, 420Y, 421W, 422Q, 423T, 509D, 521I, 524R, 532S, 533G, 534H, 535R, 593R, 598P, 599F
CDD
cd05966 (ACS)

318T

active site
172F, 173A, 174G, 200R, 203K, 205V, 312G, 317I, 318T, 340T, 341P, 342A, 366T, 367A, 370L, 393V, 394G, 395E, 396P, 418D, 419T, 420Y, 421W, 422Q, 423T, 509D, 521I, 524R, 532S, 533G, 534H, 535R, 593R, 598P, 599F
CDD
cd05966 (ACS)

340T

active site
172F, 173A, 174G, 200R, 203K, 205V, 312G, 317I, 318T, 340T, 341P, 342A, 366T, 367A, 370L, 393V, 394G, 395E, 396P, 418D, 419T, 420Y, 421W, 422Q, 423T, 509D, 521I, 524R, 532S, 533G, 534H, 535R, 593R, 598P, 599F
CDD
cd05966 (ACS)

341P

active site
172F, 173A, 174G, 200R, 203K, 205V, 312G, 317I, 318T, 340T, 341P, 342A, 366T, 367A, 370L, 393V, 394G, 395E, 396P, 418D, 419T, 420Y, 421W, 422Q, 423T, 509D, 521I, 524R, 532S, 533G, 534H, 535R, 593R, 598P, 599F
CDD
cd05966 (ACS)

342A

active site
172F, 173A, 174G, 200R, 203K, 205V, 312G, 317I, 318T, 340T, 341P, 342A, 366T, 367A, 370L, 393V, 394G, 395E, 396P, 418D, 419T, 420Y, 421W, 422Q, 423T, 509D, 521I, 524R, 532S, 533G, 534H, 535R, 593R, 598P, 599F
CDD
cd05966 (ACS)

366T

active site
172F, 173A, 174G, 200R, 203K, 205V, 312G, 317I, 318T, 340T, 341P, 342A, 366T, 367A, 370L, 393V, 394G, 395E, 396P, 418D, 419T, 420Y, 421W, 422Q, 423T, 509D, 521I, 524R, 532S, 533G, 534H, 535R, 593R, 598P, 599F
CDD
cd05966 (ACS)

367A

active site
172F, 173A, 174G, 200R, 203K, 205V, 312G, 317I, 318T, 340T, 341P, 342A, 366T, 367A, 370L, 393V, 394G, 395E, 396P, 418D, 419T, 420Y, 421W, 422Q, 423T, 509D, 521I, 524R, 532S, 533G, 534H, 535R, 593R, 598P, 599F
CDD
cd05966 (ACS)

370L

active site
172F, 173A, 174G, 200R, 203K, 205V, 312G, 317I, 318T, 340T, 341P, 342A, 366T, 367A, 370L, 393V, 394G, 395E, 396P, 418D, 419T, 420Y, 421W, 422Q, 423T, 509D, 521I, 524R, 532S, 533G, 534H, 535R, 593R, 598P, 599F
CDD
cd05966 (ACS)

393V

active site
172F, 173A, 174G, 200R, 203K, 205V, 312G, 317I, 318T, 340T, 341P, 342A, 366T, 367A, 370L, 393V, 394G, 395E, 396P, 418D, 419T, 420Y, 421W, 422Q, 423T, 509D, 521I, 524R, 532S, 533G, 534H, 535R, 593R, 598P, 599F
CDD
cd05966 (ACS)

394G

active site
172F, 173A, 174G, 200R, 203K, 205V, 312G, 317I, 318T, 340T, 341P, 342A, 366T, 367A, 370L, 393V, 394G, 395E, 396P, 418D, 419T, 420Y, 421W, 422Q, 423T, 509D, 521I, 524R, 532S, 533G, 534H, 535R, 593R, 598P, 599F
CDD
cd05966 (ACS)

395E

active site
172F, 173A, 174G, 200R, 203K, 205V, 312G, 317I, 318T, 340T, 341P, 342A, 366T, 367A, 370L, 393V, 394G, 395E, 396P, 418D, 419T, 420Y, 421W, 422Q, 423T, 509D, 521I, 524R, 532S, 533G, 534H, 535R, 593R, 598P, 599F
CDD
cd05966 (ACS)

396P

active site
172F, 173A, 174G, 200R, 203K, 205V, 312G, 317I, 318T, 340T, 341P, 342A, 366T, 367A, 370L, 393V, 394G, 395E, 396P, 418D, 419T, 420Y, 421W, 422Q, 423T, 509D, 521I, 524R, 532S, 533G, 534H, 535R, 593R, 598P, 599F
CDD
cd05966 (ACS)

418D

active site
172F, 173A, 174G, 200R, 203K, 205V, 312G, 317I, 318T, 340T, 341P, 342A, 366T, 367A, 370L, 393V, 394G, 395E, 396P, 418D, 419T, 420Y, 421W, 422Q, 423T, 509D, 521I, 524R, 532S, 533G, 534H, 535R, 593R, 598P, 599F
CDD
cd05966 (ACS)

419T

active site
172F, 173A, 174G, 200R, 203K, 205V, 312G, 317I, 318T, 340T, 341P, 342A, 366T, 367A, 370L, 393V, 394G, 395E, 396P, 418D, 419T, 420Y, 421W, 422Q, 423T, 509D, 521I, 524R, 532S, 533G, 534H, 535R, 593R, 598P, 599F
CDD
cd05966 (ACS)

420Y

active site
172F, 173A, 174G, 200R, 203K, 205V, 312G, 317I, 318T, 340T, 341P, 342A, 366T, 367A, 370L, 393V, 394G, 395E, 396P, 418D, 419T, 420Y, 421W, 422Q, 423T, 509D, 521I, 524R, 532S, 533G, 534H, 535R, 593R, 598P, 599F
CDD
cd05966 (ACS)

421W

active site
172F, 173A, 174G, 200R, 203K, 205V, 312G, 317I, 318T, 340T, 341P, 342A, 366T, 367A, 370L, 393V, 394G, 395E, 396P, 418D, 419T, 420Y, 421W, 422Q, 423T, 509D, 521I, 524R, 532S, 533G, 534H, 535R, 593R, 598P, 599F
CDD
cd05966 (ACS)

422Q

active site
172F, 173A, 174G, 200R, 203K, 205V, 312G, 317I, 318T, 340T, 341P, 342A, 366T, 367A, 370L, 393V, 394G, 395E, 396P, 418D, 419T, 420Y, 421W, 422Q, 423T, 509D, 521I, 524R, 532S, 533G, 534H, 535R, 593R, 598P, 599F
CDD
cd05966 (ACS)

423T

active site
172F, 173A, 174G, 200R, 203K, 205V, 312G, 317I, 318T, 340T, 341P, 342A, 366T, 367A, 370L, 393V, 394G, 395E, 396P, 418D, 419T, 420Y, 421W, 422Q, 423T, 509D, 521I, 524R, 532S, 533G, 534H, 535R, 593R, 598P, 599F
CDD
cd05966 (ACS)

509D

active site
172F, 173A, 174G, 200R, 203K, 205V, 312G, 317I, 318T, 340T, 341P, 342A, 366T, 367A, 370L, 393V, 394G, 395E, 396P, 418D, 419T, 420Y, 421W, 422Q, 423T, 509D, 521I, 524R, 532S, 533G, 534H, 535R, 593R, 598P, 599F
CDD
cd05966 (ACS)

521I

active site
172F, 173A, 174G, 200R, 203K, 205V, 312G, 317I, 318T, 340T, 341P, 342A, 366T, 367A, 370L, 393V, 394G, 395E, 396P, 418D, 419T, 420Y, 421W, 422Q, 423T, 509D, 521I, 524R, 532S, 533G, 534H, 535R, 593R, 598P, 599F
CDD
cd05966 (ACS)

524R

active site
172F, 173A, 174G, 200R, 203K, 205V, 312G, 317I, 318T, 340T, 341P, 342A, 366T, 367A, 370L, 393V, 394G, 395E, 396P, 418D, 419T, 420Y, 421W, 422Q, 423T, 509D, 521I, 524R, 532S, 533G, 534H, 535R, 593R, 598P, 599F
CDD
cd05966 (ACS)

532S

active site
172F, 173A, 174G, 200R, 203K, 205V, 312G, 317I, 318T, 340T, 341P, 342A, 366T, 367A, 370L, 393V, 394G, 395E, 396P, 418D, 419T, 420Y, 421W, 422Q, 423T, 509D, 521I, 524R, 532S, 533G, 534H, 535R, 593R, 598P, 599F
CDD
cd05966 (ACS)

533G

active site
172F, 173A, 174G, 200R, 203K, 205V, 312G, 317I, 318T, 340T, 341P, 342A, 366T, 367A, 370L, 393V, 394G, 395E, 396P, 418D, 419T, 420Y, 421W, 422Q, 423T, 509D, 521I, 524R, 532S, 533G, 534H, 535R, 593R, 598P, 599F
CDD
cd05966 (ACS)

534H

active site
172F, 173A, 174G, 200R, 203K, 205V, 312G, 317I, 318T, 340T, 341P, 342A, 366T, 367A, 370L, 393V, 394G, 395E, 396P, 418D, 419T, 420Y, 421W, 422Q, 423T, 509D, 521I, 524R, 532S, 533G, 534H, 535R, 593R, 598P, 599F
CDD
cd05966 (ACS)

535R

active site
172F, 173A, 174G, 200R, 203K, 205V, 312G, 317I, 318T, 340T, 341P, 342A, 366T, 367A, 370L, 393V, 394G, 395E, 396P, 418D, 419T, 420Y, 421W, 422Q, 423T, 509D, 521I, 524R, 532S, 533G, 534H, 535R, 593R, 598P, 599F
CDD
cd05966 (ACS)

593R

active site
172F, 173A, 174G, 200R, 203K, 205V, 312G, 317I, 318T, 340T, 341P, 342A, 366T, 367A, 370L, 393V, 394G, 395E, 396P, 418D, 419T, 420Y, 421W, 422Q, 423T, 509D, 521I, 524R, 532S, 533G, 534H, 535R, 593R, 598P, 599F
CDD
cd05966 (ACS)

598P

active site
172F, 173A, 174G, 200R, 203K, 205V, 312G, 317I, 318T, 340T, 341P, 342A, 366T, 367A, 370L, 393V, 394G, 395E, 396P, 418D, 419T, 420Y, 421W, 422Q, 423T, 509D, 521I, 524R, 532S, 533G, 534H, 535R, 593R, 598P, 599F
CDD
cd05966 (ACS)

599F

active site
172F, 173A, 174G, 200R, 203K, 205V, 312G, 317I, 318T, 340T, 341P, 342A, 366T, 367A, 370L, 393V, 394G, 395E, 396P, 418D, 419T, 420Y, 421W, 422Q, 423T, 509D, 521I, 524R, 532S, 533G, 534H, 535R, 593R, 598P, 599F
CDD
cd05966 (ACS)
acyl-activating en...

268L

acyl-activating enzyme (AAE) consensus motif
268L, 271T, 272S, 273G, 274S, 275T, 276G, 278P, 279K
CDD
cd05966 (ACS)

271T

acyl-activating enzyme (AAE) consensus motif
268L, 271T, 272S, 273G, 274S, 275T, 276G, 278P, 279K
CDD
cd05966 (ACS)

272S

acyl-activating enzyme (AAE) consensus motif
268L, 271T, 272S, 273G, 274S, 275T, 276G, 278P, 279K
CDD
cd05966 (ACS)

273G

acyl-activating enzyme (AAE) consensus motif
268L, 271T, 272S, 273G, 274S, 275T, 276G, 278P, 279K
CDD
cd05966 (ACS)

274S

acyl-activating enzyme (AAE) consensus motif
268L, 271T, 272S, 273G, 274S, 275T, 276G, 278P, 279K
CDD
cd05966 (ACS)

275T

acyl-activating enzyme (AAE) consensus motif
268L, 271T, 272S, 273G, 274S, 275T, 276G, 278P, 279K
CDD
cd05966 (ACS)

276G

acyl-activating enzyme (AAE) consensus motif
268L, 271T, 272S, 273G, 274S, 275T, 276G, 278P, 279K
CDD
cd05966 (ACS)

278P

acyl-activating enzyme (AAE) consensus motif
268L, 271T, 272S, 273G, 274S, 275T, 276G, 278P, 279K
CDD
cd05966 (ACS)

279K

acyl-activating enzyme (AAE) consensus motif
268L, 271T, 272S, 273G, 274S, 275T, 276G, 278P, 279K
CDD
cd05966 (ACS)
acetate binding si...

317I

acetate binding site
317I, 318T, 393V, 394G, 421W
CDD
cd05966 (ACS)

318T

acetate binding site
317I, 318T, 393V, 394G, 421W
CDD
cd05966 (ACS)

393V

acetate binding site
317I, 318T, 393V, 394G, 421W
CDD
cd05966 (ACS)

394G

acetate binding site
317I, 318T, 393V, 394G, 421W
CDD
cd05966 (ACS)

421W

acetate binding site
317I, 318T, 393V, 394G, 421W
CDD
cd05966 (ACS)
AMP binding site c...

317I

AMP binding site
317I, 318T, 393V, 394G, 395E, 396P, 418D, 419T, 420Y, 421W, 422Q, 423T, 509D, 521I, 524R, 535R
CDD
cd05966 (ACS)

318T

AMP binding site
317I, 318T, 393V, 394G, 395E, 396P, 418D, 419T, 420Y, 421W, 422Q, 423T, 509D, 521I, 524R, 535R
CDD
cd05966 (ACS)

393V

AMP binding site
317I, 318T, 393V, 394G, 395E, 396P, 418D, 419T, 420Y, 421W, 422Q, 423T, 509D, 521I, 524R, 535R
CDD
cd05966 (ACS)

394G

AMP binding site
317I, 318T, 393V, 394G, 395E, 396P, 418D, 419T, 420Y, 421W, 422Q, 423T, 509D, 521I, 524R, 535R
CDD
cd05966 (ACS)

395E

AMP binding site
317I, 318T, 393V, 394G, 395E, 396P, 418D, 419T, 420Y, 421W, 422Q, 423T, 509D, 521I, 524R, 535R
CDD
cd05966 (ACS)

396P

AMP binding site
317I, 318T, 393V, 394G, 395E, 396P, 418D, 419T, 420Y, 421W, 422Q, 423T, 509D, 521I, 524R, 535R
CDD
cd05966 (ACS)

418D

AMP binding site
317I, 318T, 393V, 394G, 395E, 396P, 418D, 419T, 420Y, 421W, 422Q, 423T, 509D, 521I, 524R, 535R
CDD
cd05966 (ACS)

419T

AMP binding site
317I, 318T, 393V, 394G, 395E, 396P, 418D, 419T, 420Y, 421W, 422Q, 423T, 509D, 521I, 524R, 535R
CDD
cd05966 (ACS)

420Y

AMP binding site
317I, 318T, 393V, 394G, 395E, 396P, 418D, 419T, 420Y, 421W, 422Q, 423T, 509D, 521I, 524R, 535R
CDD
cd05966 (ACS)

421W

AMP binding site
317I, 318T, 393V, 394G, 395E, 396P, 418D, 419T, 420Y, 421W, 422Q, 423T, 509D, 521I, 524R, 535R
CDD
cd05966 (ACS)

422Q

AMP binding site
317I, 318T, 393V, 394G, 395E, 396P, 418D, 419T, 420Y, 421W, 422Q, 423T, 509D, 521I, 524R, 535R
CDD
cd05966 (ACS)

423T

AMP binding site
317I, 318T, 393V, 394G, 395E, 396P, 418D, 419T, 420Y, 421W, 422Q, 423T, 509D, 521I, 524R, 535R
CDD
cd05966 (ACS)

509D

AMP binding site
317I, 318T, 393V, 394G, 395E, 396P, 418D, 419T, 420Y, 421W, 422Q, 423T, 509D, 521I, 524R, 535R
CDD
cd05966 (ACS)

521I

AMP binding site
317I, 318T, 393V, 394G, 395E, 396P, 418D, 419T, 420Y, 421W, 422Q, 423T, 509D, 521I, 524R, 535R
CDD
cd05966 (ACS)

524R

AMP binding site
317I, 318T, 393V, 394G, 395E, 396P, 418D, 419T, 420Y, 421W, 422Q, 423T, 509D, 521I, 524R, 535R
CDD
cd05966 (ACS)

535R

AMP binding site
317I, 318T, 393V, 394G, 395E, 396P, 418D, 419T, 420Y, 421W, 422Q, 423T, 509D, 521I, 524R, 535R
CDD
cd05966 (ACS)

Protein sequence

>MIA_03334_1
MSGIAESSIEGRPTPQAFFDKHPSEPHLNNLEHYKELYKESIENPNKFFGNLAHELLTWDHDFTTVSSGGFEHGDMAWFL
EGRLNASYNCVDRHAAKNPDKVAIIYEADDAKDSRKITYGELMAEVSRVAGVLKSFGVTKGDSVAVYLPMIPEALIALLA
ISRIGAVHSVIFAGFSSGSLKDRVNDAKSKVIITTDEGKRGGKTVYTKKIVDEGLKDAPSVEKVLVYQRTGNQVPWTEGR
DFWWHEEVDKHRPYLAPVPVSSEDPLFLLYTSGSTGSPKGVVHVTGGYLLGAAATCKYVFDIHPDDILFTAGDVGWITGH
TYAFYGPLLLGATTIIFEGTPAYPDYSRYWEIVEKYKATQFYVAPTALRLLKRAGEEFVKKHDLSSLRTLGSVGEPIAAE
IWEWYNEHVGNKDCHISDTYWQTETGSHIIAPLAGVTPMKPGSATLPFFGIDLVLIDPVSGEEIKGNDVEGVLAIRKPWP
SIARTVYGSHKRYLETYLKPYPGYYFTGDGAARDKEGYYWIRGRVDDVVNVSGHRLSTAEIEAALIQHAAVGEAAVVGVA
DELTGQAVIAFVSLKGDTAGSDELRKELILQVRREIGPFSAPKAVLIVDDLPKTRSGKIMRRILRKIVSGEADSIGDTST
LSEPHVVEDIIASVDKQYKVPK

GO term prediction

Biological Process

GO:0008152 metabolic process
GO:0019427 acetyl-CoA biosynthetic process from acetate

Molecular Function

GO:0003824 catalytic activity
GO:0003987 acetate-CoA ligase activity
GO:0016208 AMP binding

Cellular Component

None predicted.

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Entry type

Status

Per-residue features