Protein
MIA_03295_1
Length
89 amino acids
Browser: contig04:808542-808928+
Protein function
| EGGNOG: | 0PQY8 | TIM8 | Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space. The TIM8-TIM13 complex is non essential and only mediates the import of few proteins, while the predominant TIM9-TIM10 70 kDa complex is crucial and mediates the import of much more proteins |
|---|---|---|---|
| SGD closest match: | S000007348 | TIM8 | Mitochondrial import inner membrane translocase subunit TIM8 |
| CGD closest match: | CAL0000198973 | TIM8 | Mitochondrial import inner membrane translocase subunit TIM8 |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MCA_02522_1 | 78.409% | 88 | 1.15e-48 | MCA_02522_1 |
| A0A1E3PM95_9ASCO | 72.941% | 85 | 1.66e-42 | Mitochondrial import inner membrane translocase subunit TIM8 OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_82340 PE=3 SV=1 |
| A0A060T452_BLAAD | 62.791% | 86 | 1.14e-38 | ARAD1A14278p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1A14278g PE=3 SV=1 |
| UniRef50_A0A061AQW9 | 61.728% | 81 | 3.05e-32 | CYFA0S04e01486g1_1 n=1 Tax=Cyberlindnera fabianii TaxID=36022 RepID=A0A061AQW9_CYBFA |
| TIM8_CANAL | 59.302% | 86 | 1.79e-33 | Mitochondrial import inner membrane translocase subunit TIM8 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=TIM8 PE=3 SV=2 |
| TIM8_YEAST | 55.814% | 86 | 7.26e-31 | Mitochondrial import inner membrane translocase subunit TIM8 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=TIM8 PE=1 SV=1 |
| A0A1E4TEN8_9ASCO | 51.136% | 88 | 5.46e-31 | Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_103059 PE=3 SV=1 |
| Q6C9F7_YARLI | 51.220% | 82 | 5.34e-30 | YALI0D11572p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_D11572g PE=3 SV=2 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.0456
Protein family membership
None predicted.
Domains and repeats
-
Domain
1
10
20
30
40
50
60
70
80
89
Detailed signature matches
Protein sequence
>MIA_03295_1 MSEIDSQSLANLDASTRKEIMEWIESENSKAKVQTSIHNFTDMCFKKCITKINSSALDRNEESCLTNCLNRFLDTNINIV KMIQQTSSQ
GO term prediction
Biological Process
None predicted.
Molecular Function
None predicted.
Cellular Component
None predicted.