Protein

MIA_03277_1

Length
450 amino acids

Browser: contig04:758917-760456-

Protein function

EGGNOG:0PG5KARG8Acetylornithine aminotransferase
SGD closest match:S000005500ARG8Acetylornithine aminotransferase, mitochondrial
CGD closest match:CAL0000177288ARG8Acetylornithine transaminase

Protein alignments

%idAln lengthE-value
MCA_00713_167.647%4420.0MCA_00713_1
A0A0J9X3N7_GEOCN53.229%4497.99e-166Similar to Saccharomyces cerevisiae YOL140W ARG8 Acetylornithine aminotransferase OS=Geotrichum candidum GN=BN980_GECA01s10999g PE=3 SV=1
A0A1E4TGD1_9ASCO56.359%4019.89e-159Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_2505 PE=3 SV=1
UniRef50_B8MLE751.494%4355.83e-154Acetylornithine aminotransferase n=6 Tax=saccharomyceta TaxID=716545 RepID=B8MLE7_TALSN
A0A167FC39_9ASCO53.535%3961.28e-155Acetylornithine transaminase OS=Sugiyamaella lignohabitans GN=ARG8 PE=3 SV=1
ARGD_YARLI52.594%4247.57e-153Acetylornithine aminotransferase, mitochondrial OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=ARG8 PE=3 SV=1
A0A060THE1_BLAAD51.980%4043.73e-149ARAD1D30206p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D30206g PE=3 SV=1
A0A1E3PMU9_9ASCO52.099%4052.27e-148Acetylornithine aminotransferase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_73893 PE=3 SV=1
A0A1D8PM83_CANAL51.244%4021.32e-144Acetylornithine transaminase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=ARG8 PE=3 SV=1
ARGD_YEAST49.624%3993.89e-129Acetylornithine aminotransferase, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ARG8 PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.9889
Predicted cleavage: 27

Protein family membership

Domains and repeats

  1. Domain
  2. Domain
1 50 100 150 200 250 300 350 400 450 450

Detailed signature matches

  1. Family IPR005814
    Aminotransferase class-III
    1. PS00600 (AA_TRANSFE...)
    2. cd00610 (OAT_like)
    3. PIRSF000521 (Transa...)
    4. PF00202 (Aminotran_3)
  2. Family IPR004636
    Acetylornithine/Succinylornithine transaminase family
    1. TIGR00707
    2. MF_01107 (ArgD_amin...)
  3. Domain IPR015422
    Pyridoxal phosphate-dependent transferase, subdomain 2
    1. G3DSA:3.90.11...
  4. Domain IPR015424
    Pyridoxal phosphate-dependent transferase
    1. SSF53383 (PLP-depen...)
  5. Domain IPR015421
    Pyridoxal phosphate-dependent transferase, major region, subdomain 1
    1. G3DSA:3.40.64...

Residue annotation

  1. inhibitor-cofactor...
  2. pyridoxal 5'-phosp...
  3. catalytic residue ...

Protein sequence

>MIA_03277_1
MLSSAFKSVRARNGAVSAVSTQIRSYAKKKSVDTPTAFVEKYAHYQVPTYSRPNTVMERGEGSFLYDTEGKKYIDLTAGI
AVNSLGHCPPLVTYTLMKQASTLVHSSNMYYNKTAPILSEKLVEATINSGGMKDATAVFLSNSGTESNEAALKFARKYGK
VVGKGGENTQKTGLVSFNGAFHGRSFGALSMTPNPKYQGPFAPLVPDVTYGDFNDIAGLQTLITENTAGVIVEPIQGEGG
INVADPEFLIALRKRCDEVDAILIFDEIQAGLSRTGKFWAHSHAGPEAHPDIITCAKALGNGFPIGAVIVNSKVNDIIKI
GDHGTTYGGNPLAAAVAIEVLKELTSKSLLDGVATRARAIEQKFDQIIETYPNLATGRRGVGLMQGLQLSIDPSHVISKA
HQKGLLLLSCGKNTIRLVPPLNIPYPTLVAGLSTLKKIFKDINDDINGKI

GO term prediction

Biological Process

GO:0006525 arginine metabolic process

Molecular Function

GO:0003824 catalytic activity
GO:0008483 transaminase activity
GO:0030170 pyridoxal phosphate binding

Cellular Component

None predicted.