Protein

MCA_00713_1

Length
448 amino acids

Gene name: ARG8

Description: Acetylornithine aminotransferase, mitochondrial

Browser: contigA:2233057-2234601-

RNA-seq: read pairs 2845, FPKM 78.3, percentile rank 74.9% (100% = highest expression)

Protein function

Annotation:ARG8Acetylornithine aminotransferase, mitochondrial
KEGG:K00818E2.6.1.11 acetylornithine aminotransferase [EC:2.6.1.11]
EGGNOG:0PG5KARG8Acetylornithine aminotransferase
SGD closest match:S000005500ARG8Acetylornithine aminotransferase, mitochondrial
CGD closest match:CAL0000177288ARG8Acetylornithine transaminase

Protein alignments

%idAln lengthE-value
MIA_03277_167.65%4420.0MIA_03277_1
A0A0J9X3N7_GEOCN58.22%4500.0Similar to Saccharomyces cerevisiae YOL140W ARG8 Acetylornithine aminotransferase OS=Geotrichum candidum GN=BN980_GECA01s10999g PE=3 SV=1
UniRef50_B8MLE756.52%4141e-163Acetylornithine aminotransferase n=6 Tax=saccharomyceta TaxID=716545 RepID=B8MLE7_TALSN
A0A1E4TGD1_9ASCO57.75%4006e-166Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_2505 PE=3 SV=1
A0A167FC39_9ASCO53.35%4034e-159Acetylornithine transaminase OS=Sugiyamaella lignohabitans GN=ARG8 PE=3 SV=1
ARGD_YARLI53.55%4094e-157Acetylornithine aminotransferase, mitochondrial OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=ARG8 PE=3 SV=1
A0A060THE1_BLAAD53.87%4014e-155ARAD1D30206p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D30206g PE=3 SV=1
A0A1E3PMU9_9ASCO51.57%4132e-150Acetylornithine aminotransferase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_73893 PE=3 SV=1
A0A1D8PM83_CANAL51.87%4013e-145Acetylornithine transaminase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=ARG8 PE=3 SV=1
ARGD_YEAST49.38%4031e-130Acetylornithine aminotransferase, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ARG8 PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.9165
Predicted cleavage: 32

Protein family membership

Domains and repeats

  1. Domain
  2. Domain
1 50 100 150 200 250 300 350 400 448

Detailed signature matches

  1. Family IPR005814
    Aminotransferase class-III
    1. PS00600 (AA_TRANSFE...)
    2. cd00610 (OAT_like)
    3. PIRSF000521 (Transa...)
    4. PF00202 (Aminotran_3)
  2. Family IPR004636
    Acetylornithine/Succinylornithine transaminase family
    1. TIGR00707
    2. MF_01107 (ArgD_amin...)
  3. Domain IPR015422
    Pyridoxal phosphate-dependent transferase, subdomain 2
    1. G3DSA:3.90.11...
  4. Domain IPR015424
    Pyridoxal phosphate-dependent transferase
    1. SSF53383 (PLP-depen...)
  5. Domain IPR015421
    Pyridoxal phosphate-dependent transferase, major region, subdomain 1
    1. G3DSA:3.40.64...

Residue annotation

  1. inhibitor-cofactor...
  2. pyridoxal 5'-phosp...
  3. catalytic residue ...

Protein sequence

>MCA_00713_1
MLSLVSRLKSTNTFAKVACSTSKAVNGARLYSKIHEETPSSFVQEYSPYLVPTYSRPTTIMERGEGSYIFDSEGKQYIDL
TAGIAVNSLGHCPPSITKVLADQAATLVHCSNLYYNASAPVLSELLVEKTKASGGMPDAQAVFLSNSGTESNEAALKFAR
KHAKVVDGEETQKIGLVSFYHAFHGRSFGALSMTPNPKYQKPFGPLIPGVSYGEFNNVENLNTLITEKTAGVIVEPIQGE
GGIYQATPEFISALRKRCNEVNAVLIFDEIQCGLSRTGKLWAHSHFGPDAQPDIITCAKALGNGFPIGAVIVNDKVNNAI
KVGDHGTTYGGNPLASRVAIEVLKELTSESLLKGVEERAIILRNGLENLIQKYPKIATEIRGTGLIQGIQLTVSPAEIVE
KSHNNGLLILTCGTNTLRFVPPLNIPKATLEKGLSILDKIFGEINQKL

GO term prediction

Biological Process

GO:0006525 arginine metabolic process

Molecular Function

GO:0003824 catalytic activity
GO:0008483 transaminase activity
GO:0030170 pyridoxal phosphate binding

Cellular Component

None predicted.