MIA_03268_1

Protein

Length

290 amino acids

Protein function

EGGNOG:	0PF95	FG00407.1	Sporulation protein SPS19
SGD closest match:	S000005146	SPS19	Peroxisomal 2,4-dienoyl-CoA reductase SPS19
CGD closest match:	CAL0000196598	SPS20	Sps20p

Protein alignments

	%id	Aln length	E-value
MCA_03583_1	69.048%	294	8.19e-135	MCA_03583_1
A0A0J9X4T4_GEOCN	65.862%	290	1.47e-129	Similar to Saccharomyces cerevisiae YNL202W SPS19 Peroxisomal 2,4-dienoyl-CoA reductase OS=Geotrichum candidum GN=BN980_GECA02s07259g PE=4 SV=1
A0A167CBW1_9ASCO	62.069%	290	4.21e-117	Sps19p OS=Sugiyamaella lignohabitans GN=SPS19 PE=4 SV=1
Q59SL5_CANAL	62.544%	283	1.08e-116	Sps20p OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=SPS20 PE=4 SV=1
Q6CD80_YARLI	61.034%	290	4.24e-116	YALI0C03003p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_C03003g PE=4 SV=1
A0A060T9V3_BLAAD	62.191%	283	2.25e-112	ARAD1D17534p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D17534g PE=4 SV=1
SPS19_YEAST	56.228%	281	3.70e-105	Peroxisomal 2,4-dienoyl-CoA reductase SPS19 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SPS19 PE=1 SV=4
UniRef50_P32573	56.228%	281	8.84e-102	Peroxisomal 2,4-dienoyl-CoA reductase SPS19 n=200 Tax=Fungi TaxID=4751 RepID=SPS19_YEAST
A0A1E3PH09_9ASCO	53.716%	296	5.70e-104	NAD(P)-binding protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_83599 PE=4 SV=1
A0A1E4TEX7_9ASCO	52.593%	270	3.58e-83	Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_25338 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.2888

Protein family membership

Short-chain dehydrogenase/reductase SDR (IPR002347)

Domains and repeats

Domain
20 - 262
NAD(P)-binding domain (IPR016040)

1 50 100 150 200 250 290

Detailed signature matches

IPR002347

Short-chain dehydrogenase/reductase SDR
1. PR00081 (GDHRDH)
  
  23 - 40
  
  PRINTS
  PR00081 (GDHRDH)
  
  228 - 248
  
  PRINTS
  PR00081 (GDHRDH)
  
  172 - 191
  
  PRINTS
  PR00081 (GDHRDH)
  
  100 - 111
  
  PRINTS
  PR00081 (GDHRDH)
  
  193 - 210
  
  PRINTS
  PR00081 (GDHRDH)
IPR016040

NAD(P)-binding domain
1. SSF51735 (NAD(P)-bi...)
  
  20 - 262
  
  SUPERFAMILY
  SSF51735 (NAD(P)-binding Rossmann-fold domains)

no IPR

Unintegrated signatures

G3DSA:3.40.50...

4 - 266

GENE3D
G3DSA:3.40.50.720 (G3DSA:3.40.50.720)
PF13561 (adh_short_C2)

30 - 262

Pfam
PF13561 (adh_short_C2)
cd05369 (TER_DECR_S...)

19 - 265

CDD
cd05369 (TER_DECR_SDR_a)

Residue annotation

NAD(P) binding sit...

28G

NAD(P) binding site
28G, 31G, 32T, 33I, 52G, 53R, 54R, 80V, 81D, 82V, 83R, 108G, 109A, 110A, 131I, 157I, 158S, 159A, 176K, 202P, 203G, 204A, 205I, 207G
CDD
cd05369 (TER_DECR_SDR_a)

31G

NAD(P) binding site
28G, 31G, 32T, 33I, 52G, 53R, 54R, 80V, 81D, 82V, 83R, 108G, 109A, 110A, 131I, 157I, 158S, 159A, 176K, 202P, 203G, 204A, 205I, 207G
CDD
cd05369 (TER_DECR_SDR_a)

32T

NAD(P) binding site
28G, 31G, 32T, 33I, 52G, 53R, 54R, 80V, 81D, 82V, 83R, 108G, 109A, 110A, 131I, 157I, 158S, 159A, 176K, 202P, 203G, 204A, 205I, 207G
CDD
cd05369 (TER_DECR_SDR_a)

33I

NAD(P) binding site
28G, 31G, 32T, 33I, 52G, 53R, 54R, 80V, 81D, 82V, 83R, 108G, 109A, 110A, 131I, 157I, 158S, 159A, 176K, 202P, 203G, 204A, 205I, 207G
CDD
cd05369 (TER_DECR_SDR_a)

52G

NAD(P) binding site
28G, 31G, 32T, 33I, 52G, 53R, 54R, 80V, 81D, 82V, 83R, 108G, 109A, 110A, 131I, 157I, 158S, 159A, 176K, 202P, 203G, 204A, 205I, 207G
CDD
cd05369 (TER_DECR_SDR_a)

53R

NAD(P) binding site
28G, 31G, 32T, 33I, 52G, 53R, 54R, 80V, 81D, 82V, 83R, 108G, 109A, 110A, 131I, 157I, 158S, 159A, 176K, 202P, 203G, 204A, 205I, 207G
CDD
cd05369 (TER_DECR_SDR_a)

54R

NAD(P) binding site
28G, 31G, 32T, 33I, 52G, 53R, 54R, 80V, 81D, 82V, 83R, 108G, 109A, 110A, 131I, 157I, 158S, 159A, 176K, 202P, 203G, 204A, 205I, 207G
CDD
cd05369 (TER_DECR_SDR_a)

80V

NAD(P) binding site
28G, 31G, 32T, 33I, 52G, 53R, 54R, 80V, 81D, 82V, 83R, 108G, 109A, 110A, 131I, 157I, 158S, 159A, 176K, 202P, 203G, 204A, 205I, 207G
CDD
cd05369 (TER_DECR_SDR_a)

81D

NAD(P) binding site
28G, 31G, 32T, 33I, 52G, 53R, 54R, 80V, 81D, 82V, 83R, 108G, 109A, 110A, 131I, 157I, 158S, 159A, 176K, 202P, 203G, 204A, 205I, 207G
CDD
cd05369 (TER_DECR_SDR_a)

82V

NAD(P) binding site
28G, 31G, 32T, 33I, 52G, 53R, 54R, 80V, 81D, 82V, 83R, 108G, 109A, 110A, 131I, 157I, 158S, 159A, 176K, 202P, 203G, 204A, 205I, 207G
CDD
cd05369 (TER_DECR_SDR_a)

83R

NAD(P) binding site
28G, 31G, 32T, 33I, 52G, 53R, 54R, 80V, 81D, 82V, 83R, 108G, 109A, 110A, 131I, 157I, 158S, 159A, 176K, 202P, 203G, 204A, 205I, 207G
CDD
cd05369 (TER_DECR_SDR_a)

108G

NAD(P) binding site
28G, 31G, 32T, 33I, 52G, 53R, 54R, 80V, 81D, 82V, 83R, 108G, 109A, 110A, 131I, 157I, 158S, 159A, 176K, 202P, 203G, 204A, 205I, 207G
CDD
cd05369 (TER_DECR_SDR_a)

109A

NAD(P) binding site
28G, 31G, 32T, 33I, 52G, 53R, 54R, 80V, 81D, 82V, 83R, 108G, 109A, 110A, 131I, 157I, 158S, 159A, 176K, 202P, 203G, 204A, 205I, 207G
CDD
cd05369 (TER_DECR_SDR_a)

110A

NAD(P) binding site
28G, 31G, 32T, 33I, 52G, 53R, 54R, 80V, 81D, 82V, 83R, 108G, 109A, 110A, 131I, 157I, 158S, 159A, 176K, 202P, 203G, 204A, 205I, 207G
CDD
cd05369 (TER_DECR_SDR_a)

131I

NAD(P) binding site
28G, 31G, 32T, 33I, 52G, 53R, 54R, 80V, 81D, 82V, 83R, 108G, 109A, 110A, 131I, 157I, 158S, 159A, 176K, 202P, 203G, 204A, 205I, 207G
CDD
cd05369 (TER_DECR_SDR_a)

157I

NAD(P) binding site
28G, 31G, 32T, 33I, 52G, 53R, 54R, 80V, 81D, 82V, 83R, 108G, 109A, 110A, 131I, 157I, 158S, 159A, 176K, 202P, 203G, 204A, 205I, 207G
CDD
cd05369 (TER_DECR_SDR_a)

158S

NAD(P) binding site
28G, 31G, 32T, 33I, 52G, 53R, 54R, 80V, 81D, 82V, 83R, 108G, 109A, 110A, 131I, 157I, 158S, 159A, 176K, 202P, 203G, 204A, 205I, 207G
CDD
cd05369 (TER_DECR_SDR_a)

159A

NAD(P) binding site
28G, 31G, 32T, 33I, 52G, 53R, 54R, 80V, 81D, 82V, 83R, 108G, 109A, 110A, 131I, 157I, 158S, 159A, 176K, 202P, 203G, 204A, 205I, 207G
CDD
cd05369 (TER_DECR_SDR_a)

176K

NAD(P) binding site
28G, 31G, 32T, 33I, 52G, 53R, 54R, 80V, 81D, 82V, 83R, 108G, 109A, 110A, 131I, 157I, 158S, 159A, 176K, 202P, 203G, 204A, 205I, 207G
CDD
cd05369 (TER_DECR_SDR_a)

202P

NAD(P) binding site
28G, 31G, 32T, 33I, 52G, 53R, 54R, 80V, 81D, 82V, 83R, 108G, 109A, 110A, 131I, 157I, 158S, 159A, 176K, 202P, 203G, 204A, 205I, 207G
CDD
cd05369 (TER_DECR_SDR_a)

203G

NAD(P) binding site
28G, 31G, 32T, 33I, 52G, 53R, 54R, 80V, 81D, 82V, 83R, 108G, 109A, 110A, 131I, 157I, 158S, 159A, 176K, 202P, 203G, 204A, 205I, 207G
CDD
cd05369 (TER_DECR_SDR_a)

204A

NAD(P) binding site
28G, 31G, 32T, 33I, 52G, 53R, 54R, 80V, 81D, 82V, 83R, 108G, 109A, 110A, 131I, 157I, 158S, 159A, 176K, 202P, 203G, 204A, 205I, 207G
CDD
cd05369 (TER_DECR_SDR_a)

205I

NAD(P) binding site
28G, 31G, 32T, 33I, 52G, 53R, 54R, 80V, 81D, 82V, 83R, 108G, 109A, 110A, 131I, 157I, 158S, 159A, 176K, 202P, 203G, 204A, 205I, 207G
CDD
cd05369 (TER_DECR_SDR_a)

207G

NAD(P) binding site
28G, 31G, 32T, 33I, 52G, 53R, 54R, 80V, 81D, 82V, 83R, 108G, 109A, 110A, 131I, 157I, 158S, 159A, 176K, 202P, 203G, 204A, 205I, 207G
CDD
cd05369 (TER_DECR_SDR_a)
substrate binding ...

53R

substrate binding site
53R, 83R, 110A, 111G, 112N, 113F, 121S, 123N, 124A, 127T, 159A, 161L, 172A, 204A
CDD
cd05369 (TER_DECR_SDR_a)

83R

substrate binding site
53R, 83R, 110A, 111G, 112N, 113F, 121S, 123N, 124A, 127T, 159A, 161L, 172A, 204A
CDD
cd05369 (TER_DECR_SDR_a)

110A

substrate binding site
53R, 83R, 110A, 111G, 112N, 113F, 121S, 123N, 124A, 127T, 159A, 161L, 172A, 204A
CDD
cd05369 (TER_DECR_SDR_a)

111G

substrate binding site
53R, 83R, 110A, 111G, 112N, 113F, 121S, 123N, 124A, 127T, 159A, 161L, 172A, 204A
CDD
cd05369 (TER_DECR_SDR_a)

112N

substrate binding site
53R, 83R, 110A, 111G, 112N, 113F, 121S, 123N, 124A, 127T, 159A, 161L, 172A, 204A
CDD
cd05369 (TER_DECR_SDR_a)

113F

substrate binding site
53R, 83R, 110A, 111G, 112N, 113F, 121S, 123N, 124A, 127T, 159A, 161L, 172A, 204A
CDD
cd05369 (TER_DECR_SDR_a)

121S

substrate binding site
53R, 83R, 110A, 111G, 112N, 113F, 121S, 123N, 124A, 127T, 159A, 161L, 172A, 204A
CDD
cd05369 (TER_DECR_SDR_a)

123N

substrate binding site
53R, 83R, 110A, 111G, 112N, 113F, 121S, 123N, 124A, 127T, 159A, 161L, 172A, 204A
CDD
cd05369 (TER_DECR_SDR_a)

124A

substrate binding site
53R, 83R, 110A, 111G, 112N, 113F, 121S, 123N, 124A, 127T, 159A, 161L, 172A, 204A
CDD
cd05369 (TER_DECR_SDR_a)

127T

substrate binding site
53R, 83R, 110A, 111G, 112N, 113F, 121S, 123N, 124A, 127T, 159A, 161L, 172A, 204A
CDD
cd05369 (TER_DECR_SDR_a)

159A

substrate binding site
53R, 83R, 110A, 111G, 112N, 113F, 121S, 123N, 124A, 127T, 159A, 161L, 172A, 204A
CDD
cd05369 (TER_DECR_SDR_a)

161L

substrate binding site
53R, 83R, 110A, 111G, 112N, 113F, 121S, 123N, 124A, 127T, 159A, 161L, 172A, 204A
CDD
cd05369 (TER_DECR_SDR_a)

172A

substrate binding site
53R, 83R, 110A, 111G, 112N, 113F, 121S, 123N, 124A, 127T, 159A, 161L, 172A, 204A
CDD
cd05369 (TER_DECR_SDR_a)

204A

substrate binding site
53R, 83R, 110A, 111G, 112N, 113F, 121S, 123N, 124A, 127T, 159A, 161L, 172A, 204A
CDD
cd05369 (TER_DECR_SDR_a)
homotetramer inter...

85V

homotetramer interface
85V, 116P, 117F, 118A, 120L, 121S, 122T, 125F, 126K, 129V, 133L, 134V, 137Y, 138N, 141K, 145E, 148R, 161L, 165G, 166T, 167P, 168L, 170S, 173C, 174A, 177A, 178G, 181A, 182L, 184N, 185N, 186L, 187A, 188I, 189E, 190L, 191G, 193L, 204A, 227I, 228P, 229L, 231A, 232M, 233G, 237D, 240E, 241G, 244F, 249A, 251K, 252Y, 253I, 254S, 255G, 256T, 258L, 259V, 260V, 261D, 262A, 263S, 264Q, 265W
CDD
cd05369 (TER_DECR_SDR_a)

116P

homotetramer interface
85V, 116P, 117F, 118A, 120L, 121S, 122T, 125F, 126K, 129V, 133L, 134V, 137Y, 138N, 141K, 145E, 148R, 161L, 165G, 166T, 167P, 168L, 170S, 173C, 174A, 177A, 178G, 181A, 182L, 184N, 185N, 186L, 187A, 188I, 189E, 190L, 191G, 193L, 204A, 227I, 228P, 229L, 231A, 232M, 233G, 237D, 240E, 241G, 244F, 249A, 251K, 252Y, 253I, 254S, 255G, 256T, 258L, 259V, 260V, 261D, 262A, 263S, 264Q, 265W
CDD
cd05369 (TER_DECR_SDR_a)

117F

homotetramer interface
85V, 116P, 117F, 118A, 120L, 121S, 122T, 125F, 126K, 129V, 133L, 134V, 137Y, 138N, 141K, 145E, 148R, 161L, 165G, 166T, 167P, 168L, 170S, 173C, 174A, 177A, 178G, 181A, 182L, 184N, 185N, 186L, 187A, 188I, 189E, 190L, 191G, 193L, 204A, 227I, 228P, 229L, 231A, 232M, 233G, 237D, 240E, 241G, 244F, 249A, 251K, 252Y, 253I, 254S, 255G, 256T, 258L, 259V, 260V, 261D, 262A, 263S, 264Q, 265W
CDD
cd05369 (TER_DECR_SDR_a)

118A

homotetramer interface
85V, 116P, 117F, 118A, 120L, 121S, 122T, 125F, 126K, 129V, 133L, 134V, 137Y, 138N, 141K, 145E, 148R, 161L, 165G, 166T, 167P, 168L, 170S, 173C, 174A, 177A, 178G, 181A, 182L, 184N, 185N, 186L, 187A, 188I, 189E, 190L, 191G, 193L, 204A, 227I, 228P, 229L, 231A, 232M, 233G, 237D, 240E, 241G, 244F, 249A, 251K, 252Y, 253I, 254S, 255G, 256T, 258L, 259V, 260V, 261D, 262A, 263S, 264Q, 265W
CDD
cd05369 (TER_DECR_SDR_a)

120L

homotetramer interface
85V, 116P, 117F, 118A, 120L, 121S, 122T, 125F, 126K, 129V, 133L, 134V, 137Y, 138N, 141K, 145E, 148R, 161L, 165G, 166T, 167P, 168L, 170S, 173C, 174A, 177A, 178G, 181A, 182L, 184N, 185N, 186L, 187A, 188I, 189E, 190L, 191G, 193L, 204A, 227I, 228P, 229L, 231A, 232M, 233G, 237D, 240E, 241G, 244F, 249A, 251K, 252Y, 253I, 254S, 255G, 256T, 258L, 259V, 260V, 261D, 262A, 263S, 264Q, 265W
CDD
cd05369 (TER_DECR_SDR_a)

121S

homotetramer interface
85V, 116P, 117F, 118A, 120L, 121S, 122T, 125F, 126K, 129V, 133L, 134V, 137Y, 138N, 141K, 145E, 148R, 161L, 165G, 166T, 167P, 168L, 170S, 173C, 174A, 177A, 178G, 181A, 182L, 184N, 185N, 186L, 187A, 188I, 189E, 190L, 191G, 193L, 204A, 227I, 228P, 229L, 231A, 232M, 233G, 237D, 240E, 241G, 244F, 249A, 251K, 252Y, 253I, 254S, 255G, 256T, 258L, 259V, 260V, 261D, 262A, 263S, 264Q, 265W
CDD
cd05369 (TER_DECR_SDR_a)

122T

homotetramer interface
85V, 116P, 117F, 118A, 120L, 121S, 122T, 125F, 126K, 129V, 133L, 134V, 137Y, 138N, 141K, 145E, 148R, 161L, 165G, 166T, 167P, 168L, 170S, 173C, 174A, 177A, 178G, 181A, 182L, 184N, 185N, 186L, 187A, 188I, 189E, 190L, 191G, 193L, 204A, 227I, 228P, 229L, 231A, 232M, 233G, 237D, 240E, 241G, 244F, 249A, 251K, 252Y, 253I, 254S, 255G, 256T, 258L, 259V, 260V, 261D, 262A, 263S, 264Q, 265W
CDD
cd05369 (TER_DECR_SDR_a)

125F

homotetramer interface
85V, 116P, 117F, 118A, 120L, 121S, 122T, 125F, 126K, 129V, 133L, 134V, 137Y, 138N, 141K, 145E, 148R, 161L, 165G, 166T, 167P, 168L, 170S, 173C, 174A, 177A, 178G, 181A, 182L, 184N, 185N, 186L, 187A, 188I, 189E, 190L, 191G, 193L, 204A, 227I, 228P, 229L, 231A, 232M, 233G, 237D, 240E, 241G, 244F, 249A, 251K, 252Y, 253I, 254S, 255G, 256T, 258L, 259V, 260V, 261D, 262A, 263S, 264Q, 265W
CDD
cd05369 (TER_DECR_SDR_a)

126K

homotetramer interface
85V, 116P, 117F, 118A, 120L, 121S, 122T, 125F, 126K, 129V, 133L, 134V, 137Y, 138N, 141K, 145E, 148R, 161L, 165G, 166T, 167P, 168L, 170S, 173C, 174A, 177A, 178G, 181A, 182L, 184N, 185N, 186L, 187A, 188I, 189E, 190L, 191G, 193L, 204A, 227I, 228P, 229L, 231A, 232M, 233G, 237D, 240E, 241G, 244F, 249A, 251K, 252Y, 253I, 254S, 255G, 256T, 258L, 259V, 260V, 261D, 262A, 263S, 264Q, 265W
CDD
cd05369 (TER_DECR_SDR_a)

129V

homotetramer interface
85V, 116P, 117F, 118A, 120L, 121S, 122T, 125F, 126K, 129V, 133L, 134V, 137Y, 138N, 141K, 145E, 148R, 161L, 165G, 166T, 167P, 168L, 170S, 173C, 174A, 177A, 178G, 181A, 182L, 184N, 185N, 186L, 187A, 188I, 189E, 190L, 191G, 193L, 204A, 227I, 228P, 229L, 231A, 232M, 233G, 237D, 240E, 241G, 244F, 249A, 251K, 252Y, 253I, 254S, 255G, 256T, 258L, 259V, 260V, 261D, 262A, 263S, 264Q, 265W
CDD
cd05369 (TER_DECR_SDR_a)

133L

homotetramer interface
85V, 116P, 117F, 118A, 120L, 121S, 122T, 125F, 126K, 129V, 133L, 134V, 137Y, 138N, 141K, 145E, 148R, 161L, 165G, 166T, 167P, 168L, 170S, 173C, 174A, 177A, 178G, 181A, 182L, 184N, 185N, 186L, 187A, 188I, 189E, 190L, 191G, 193L, 204A, 227I, 228P, 229L, 231A, 232M, 233G, 237D, 240E, 241G, 244F, 249A, 251K, 252Y, 253I, 254S, 255G, 256T, 258L, 259V, 260V, 261D, 262A, 263S, 264Q, 265W
CDD
cd05369 (TER_DECR_SDR_a)

134V

homotetramer interface
85V, 116P, 117F, 118A, 120L, 121S, 122T, 125F, 126K, 129V, 133L, 134V, 137Y, 138N, 141K, 145E, 148R, 161L, 165G, 166T, 167P, 168L, 170S, 173C, 174A, 177A, 178G, 181A, 182L, 184N, 185N, 186L, 187A, 188I, 189E, 190L, 191G, 193L, 204A, 227I, 228P, 229L, 231A, 232M, 233G, 237D, 240E, 241G, 244F, 249A, 251K, 252Y, 253I, 254S, 255G, 256T, 258L, 259V, 260V, 261D, 262A, 263S, 264Q, 265W
CDD
cd05369 (TER_DECR_SDR_a)

137Y

homotetramer interface
85V, 116P, 117F, 118A, 120L, 121S, 122T, 125F, 126K, 129V, 133L, 134V, 137Y, 138N, 141K, 145E, 148R, 161L, 165G, 166T, 167P, 168L, 170S, 173C, 174A, 177A, 178G, 181A, 182L, 184N, 185N, 186L, 187A, 188I, 189E, 190L, 191G, 193L, 204A, 227I, 228P, 229L, 231A, 232M, 233G, 237D, 240E, 241G, 244F, 249A, 251K, 252Y, 253I, 254S, 255G, 256T, 258L, 259V, 260V, 261D, 262A, 263S, 264Q, 265W
CDD
cd05369 (TER_DECR_SDR_a)

138N

homotetramer interface
85V, 116P, 117F, 118A, 120L, 121S, 122T, 125F, 126K, 129V, 133L, 134V, 137Y, 138N, 141K, 145E, 148R, 161L, 165G, 166T, 167P, 168L, 170S, 173C, 174A, 177A, 178G, 181A, 182L, 184N, 185N, 186L, 187A, 188I, 189E, 190L, 191G, 193L, 204A, 227I, 228P, 229L, 231A, 232M, 233G, 237D, 240E, 241G, 244F, 249A, 251K, 252Y, 253I, 254S, 255G, 256T, 258L, 259V, 260V, 261D, 262A, 263S, 264Q, 265W
CDD
cd05369 (TER_DECR_SDR_a)

141K

homotetramer interface
85V, 116P, 117F, 118A, 120L, 121S, 122T, 125F, 126K, 129V, 133L, 134V, 137Y, 138N, 141K, 145E, 148R, 161L, 165G, 166T, 167P, 168L, 170S, 173C, 174A, 177A, 178G, 181A, 182L, 184N, 185N, 186L, 187A, 188I, 189E, 190L, 191G, 193L, 204A, 227I, 228P, 229L, 231A, 232M, 233G, 237D, 240E, 241G, 244F, 249A, 251K, 252Y, 253I, 254S, 255G, 256T, 258L, 259V, 260V, 261D, 262A, 263S, 264Q, 265W
CDD
cd05369 (TER_DECR_SDR_a)

145E

homotetramer interface
85V, 116P, 117F, 118A, 120L, 121S, 122T, 125F, 126K, 129V, 133L, 134V, 137Y, 138N, 141K, 145E, 148R, 161L, 165G, 166T, 167P, 168L, 170S, 173C, 174A, 177A, 178G, 181A, 182L, 184N, 185N, 186L, 187A, 188I, 189E, 190L, 191G, 193L, 204A, 227I, 228P, 229L, 231A, 232M, 233G, 237D, 240E, 241G, 244F, 249A, 251K, 252Y, 253I, 254S, 255G, 256T, 258L, 259V, 260V, 261D, 262A, 263S, 264Q, 265W
CDD
cd05369 (TER_DECR_SDR_a)

148R

homotetramer interface
85V, 116P, 117F, 118A, 120L, 121S, 122T, 125F, 126K, 129V, 133L, 134V, 137Y, 138N, 141K, 145E, 148R, 161L, 165G, 166T, 167P, 168L, 170S, 173C, 174A, 177A, 178G, 181A, 182L, 184N, 185N, 186L, 187A, 188I, 189E, 190L, 191G, 193L, 204A, 227I, 228P, 229L, 231A, 232M, 233G, 237D, 240E, 241G, 244F, 249A, 251K, 252Y, 253I, 254S, 255G, 256T, 258L, 259V, 260V, 261D, 262A, 263S, 264Q, 265W
CDD
cd05369 (TER_DECR_SDR_a)

161L

homotetramer interface
85V, 116P, 117F, 118A, 120L, 121S, 122T, 125F, 126K, 129V, 133L, 134V, 137Y, 138N, 141K, 145E, 148R, 161L, 165G, 166T, 167P, 168L, 170S, 173C, 174A, 177A, 178G, 181A, 182L, 184N, 185N, 186L, 187A, 188I, 189E, 190L, 191G, 193L, 204A, 227I, 228P, 229L, 231A, 232M, 233G, 237D, 240E, 241G, 244F, 249A, 251K, 252Y, 253I, 254S, 255G, 256T, 258L, 259V, 260V, 261D, 262A, 263S, 264Q, 265W
CDD
cd05369 (TER_DECR_SDR_a)

165G

homotetramer interface
85V, 116P, 117F, 118A, 120L, 121S, 122T, 125F, 126K, 129V, 133L, 134V, 137Y, 138N, 141K, 145E, 148R, 161L, 165G, 166T, 167P, 168L, 170S, 173C, 174A, 177A, 178G, 181A, 182L, 184N, 185N, 186L, 187A, 188I, 189E, 190L, 191G, 193L, 204A, 227I, 228P, 229L, 231A, 232M, 233G, 237D, 240E, 241G, 244F, 249A, 251K, 252Y, 253I, 254S, 255G, 256T, 258L, 259V, 260V, 261D, 262A, 263S, 264Q, 265W
CDD
cd05369 (TER_DECR_SDR_a)

166T

homotetramer interface
85V, 116P, 117F, 118A, 120L, 121S, 122T, 125F, 126K, 129V, 133L, 134V, 137Y, 138N, 141K, 145E, 148R, 161L, 165G, 166T, 167P, 168L, 170S, 173C, 174A, 177A, 178G, 181A, 182L, 184N, 185N, 186L, 187A, 188I, 189E, 190L, 191G, 193L, 204A, 227I, 228P, 229L, 231A, 232M, 233G, 237D, 240E, 241G, 244F, 249A, 251K, 252Y, 253I, 254S, 255G, 256T, 258L, 259V, 260V, 261D, 262A, 263S, 264Q, 265W
CDD
cd05369 (TER_DECR_SDR_a)

167P

homotetramer interface
85V, 116P, 117F, 118A, 120L, 121S, 122T, 125F, 126K, 129V, 133L, 134V, 137Y, 138N, 141K, 145E, 148R, 161L, 165G, 166T, 167P, 168L, 170S, 173C, 174A, 177A, 178G, 181A, 182L, 184N, 185N, 186L, 187A, 188I, 189E, 190L, 191G, 193L, 204A, 227I, 228P, 229L, 231A, 232M, 233G, 237D, 240E, 241G, 244F, 249A, 251K, 252Y, 253I, 254S, 255G, 256T, 258L, 259V, 260V, 261D, 262A, 263S, 264Q, 265W
CDD
cd05369 (TER_DECR_SDR_a)

168L

homotetramer interface
85V, 116P, 117F, 118A, 120L, 121S, 122T, 125F, 126K, 129V, 133L, 134V, 137Y, 138N, 141K, 145E, 148R, 161L, 165G, 166T, 167P, 168L, 170S, 173C, 174A, 177A, 178G, 181A, 182L, 184N, 185N, 186L, 187A, 188I, 189E, 190L, 191G, 193L, 204A, 227I, 228P, 229L, 231A, 232M, 233G, 237D, 240E, 241G, 244F, 249A, 251K, 252Y, 253I, 254S, 255G, 256T, 258L, 259V, 260V, 261D, 262A, 263S, 264Q, 265W
CDD
cd05369 (TER_DECR_SDR_a)

170S

homotetramer interface
85V, 116P, 117F, 118A, 120L, 121S, 122T, 125F, 126K, 129V, 133L, 134V, 137Y, 138N, 141K, 145E, 148R, 161L, 165G, 166T, 167P, 168L, 170S, 173C, 174A, 177A, 178G, 181A, 182L, 184N, 185N, 186L, 187A, 188I, 189E, 190L, 191G, 193L, 204A, 227I, 228P, 229L, 231A, 232M, 233G, 237D, 240E, 241G, 244F, 249A, 251K, 252Y, 253I, 254S, 255G, 256T, 258L, 259V, 260V, 261D, 262A, 263S, 264Q, 265W
CDD
cd05369 (TER_DECR_SDR_a)

173C

homotetramer interface
85V, 116P, 117F, 118A, 120L, 121S, 122T, 125F, 126K, 129V, 133L, 134V, 137Y, 138N, 141K, 145E, 148R, 161L, 165G, 166T, 167P, 168L, 170S, 173C, 174A, 177A, 178G, 181A, 182L, 184N, 185N, 186L, 187A, 188I, 189E, 190L, 191G, 193L, 204A, 227I, 228P, 229L, 231A, 232M, 233G, 237D, 240E, 241G, 244F, 249A, 251K, 252Y, 253I, 254S, 255G, 256T, 258L, 259V, 260V, 261D, 262A, 263S, 264Q, 265W
CDD
cd05369 (TER_DECR_SDR_a)

174A

homotetramer interface
85V, 116P, 117F, 118A, 120L, 121S, 122T, 125F, 126K, 129V, 133L, 134V, 137Y, 138N, 141K, 145E, 148R, 161L, 165G, 166T, 167P, 168L, 170S, 173C, 174A, 177A, 178G, 181A, 182L, 184N, 185N, 186L, 187A, 188I, 189E, 190L, 191G, 193L, 204A, 227I, 228P, 229L, 231A, 232M, 233G, 237D, 240E, 241G, 244F, 249A, 251K, 252Y, 253I, 254S, 255G, 256T, 258L, 259V, 260V, 261D, 262A, 263S, 264Q, 265W
CDD
cd05369 (TER_DECR_SDR_a)

177A

homotetramer interface
85V, 116P, 117F, 118A, 120L, 121S, 122T, 125F, 126K, 129V, 133L, 134V, 137Y, 138N, 141K, 145E, 148R, 161L, 165G, 166T, 167P, 168L, 170S, 173C, 174A, 177A, 178G, 181A, 182L, 184N, 185N, 186L, 187A, 188I, 189E, 190L, 191G, 193L, 204A, 227I, 228P, 229L, 231A, 232M, 233G, 237D, 240E, 241G, 244F, 249A, 251K, 252Y, 253I, 254S, 255G, 256T, 258L, 259V, 260V, 261D, 262A, 263S, 264Q, 265W
CDD
cd05369 (TER_DECR_SDR_a)

178G

homotetramer interface
85V, 116P, 117F, 118A, 120L, 121S, 122T, 125F, 126K, 129V, 133L, 134V, 137Y, 138N, 141K, 145E, 148R, 161L, 165G, 166T, 167P, 168L, 170S, 173C, 174A, 177A, 178G, 181A, 182L, 184N, 185N, 186L, 187A, 188I, 189E, 190L, 191G, 193L, 204A, 227I, 228P, 229L, 231A, 232M, 233G, 237D, 240E, 241G, 244F, 249A, 251K, 252Y, 253I, 254S, 255G, 256T, 258L, 259V, 260V, 261D, 262A, 263S, 264Q, 265W
CDD
cd05369 (TER_DECR_SDR_a)

181A

homotetramer interface
85V, 116P, 117F, 118A, 120L, 121S, 122T, 125F, 126K, 129V, 133L, 134V, 137Y, 138N, 141K, 145E, 148R, 161L, 165G, 166T, 167P, 168L, 170S, 173C, 174A, 177A, 178G, 181A, 182L, 184N, 185N, 186L, 187A, 188I, 189E, 190L, 191G, 193L, 204A, 227I, 228P, 229L, 231A, 232M, 233G, 237D, 240E, 241G, 244F, 249A, 251K, 252Y, 253I, 254S, 255G, 256T, 258L, 259V, 260V, 261D, 262A, 263S, 264Q, 265W
CDD
cd05369 (TER_DECR_SDR_a)

182L

homotetramer interface
85V, 116P, 117F, 118A, 120L, 121S, 122T, 125F, 126K, 129V, 133L, 134V, 137Y, 138N, 141K, 145E, 148R, 161L, 165G, 166T, 167P, 168L, 170S, 173C, 174A, 177A, 178G, 181A, 182L, 184N, 185N, 186L, 187A, 188I, 189E, 190L, 191G, 193L, 204A, 227I, 228P, 229L, 231A, 232M, 233G, 237D, 240E, 241G, 244F, 249A, 251K, 252Y, 253I, 254S, 255G, 256T, 258L, 259V, 260V, 261D, 262A, 263S, 264Q, 265W
CDD
cd05369 (TER_DECR_SDR_a)

184N

homotetramer interface
85V, 116P, 117F, 118A, 120L, 121S, 122T, 125F, 126K, 129V, 133L, 134V, 137Y, 138N, 141K, 145E, 148R, 161L, 165G, 166T, 167P, 168L, 170S, 173C, 174A, 177A, 178G, 181A, 182L, 184N, 185N, 186L, 187A, 188I, 189E, 190L, 191G, 193L, 204A, 227I, 228P, 229L, 231A, 232M, 233G, 237D, 240E, 241G, 244F, 249A, 251K, 252Y, 253I, 254S, 255G, 256T, 258L, 259V, 260V, 261D, 262A, 263S, 264Q, 265W
CDD
cd05369 (TER_DECR_SDR_a)

185N

homotetramer interface
85V, 116P, 117F, 118A, 120L, 121S, 122T, 125F, 126K, 129V, 133L, 134V, 137Y, 138N, 141K, 145E, 148R, 161L, 165G, 166T, 167P, 168L, 170S, 173C, 174A, 177A, 178G, 181A, 182L, 184N, 185N, 186L, 187A, 188I, 189E, 190L, 191G, 193L, 204A, 227I, 228P, 229L, 231A, 232M, 233G, 237D, 240E, 241G, 244F, 249A, 251K, 252Y, 253I, 254S, 255G, 256T, 258L, 259V, 260V, 261D, 262A, 263S, 264Q, 265W
CDD
cd05369 (TER_DECR_SDR_a)

186L

homotetramer interface
85V, 116P, 117F, 118A, 120L, 121S, 122T, 125F, 126K, 129V, 133L, 134V, 137Y, 138N, 141K, 145E, 148R, 161L, 165G, 166T, 167P, 168L, 170S, 173C, 174A, 177A, 178G, 181A, 182L, 184N, 185N, 186L, 187A, 188I, 189E, 190L, 191G, 193L, 204A, 227I, 228P, 229L, 231A, 232M, 233G, 237D, 240E, 241G, 244F, 249A, 251K, 252Y, 253I, 254S, 255G, 256T, 258L, 259V, 260V, 261D, 262A, 263S, 264Q, 265W
CDD
cd05369 (TER_DECR_SDR_a)

187A

homotetramer interface
85V, 116P, 117F, 118A, 120L, 121S, 122T, 125F, 126K, 129V, 133L, 134V, 137Y, 138N, 141K, 145E, 148R, 161L, 165G, 166T, 167P, 168L, 170S, 173C, 174A, 177A, 178G, 181A, 182L, 184N, 185N, 186L, 187A, 188I, 189E, 190L, 191G, 193L, 204A, 227I, 228P, 229L, 231A, 232M, 233G, 237D, 240E, 241G, 244F, 249A, 251K, 252Y, 253I, 254S, 255G, 256T, 258L, 259V, 260V, 261D, 262A, 263S, 264Q, 265W
CDD
cd05369 (TER_DECR_SDR_a)

188I

homotetramer interface
85V, 116P, 117F, 118A, 120L, 121S, 122T, 125F, 126K, 129V, 133L, 134V, 137Y, 138N, 141K, 145E, 148R, 161L, 165G, 166T, 167P, 168L, 170S, 173C, 174A, 177A, 178G, 181A, 182L, 184N, 185N, 186L, 187A, 188I, 189E, 190L, 191G, 193L, 204A, 227I, 228P, 229L, 231A, 232M, 233G, 237D, 240E, 241G, 244F, 249A, 251K, 252Y, 253I, 254S, 255G, 256T, 258L, 259V, 260V, 261D, 262A, 263S, 264Q, 265W
CDD
cd05369 (TER_DECR_SDR_a)

189E

homotetramer interface
85V, 116P, 117F, 118A, 120L, 121S, 122T, 125F, 126K, 129V, 133L, 134V, 137Y, 138N, 141K, 145E, 148R, 161L, 165G, 166T, 167P, 168L, 170S, 173C, 174A, 177A, 178G, 181A, 182L, 184N, 185N, 186L, 187A, 188I, 189E, 190L, 191G, 193L, 204A, 227I, 228P, 229L, 231A, 232M, 233G, 237D, 240E, 241G, 244F, 249A, 251K, 252Y, 253I, 254S, 255G, 256T, 258L, 259V, 260V, 261D, 262A, 263S, 264Q, 265W
CDD
cd05369 (TER_DECR_SDR_a)

190L

homotetramer interface
85V, 116P, 117F, 118A, 120L, 121S, 122T, 125F, 126K, 129V, 133L, 134V, 137Y, 138N, 141K, 145E, 148R, 161L, 165G, 166T, 167P, 168L, 170S, 173C, 174A, 177A, 178G, 181A, 182L, 184N, 185N, 186L, 187A, 188I, 189E, 190L, 191G, 193L, 204A, 227I, 228P, 229L, 231A, 232M, 233G, 237D, 240E, 241G, 244F, 249A, 251K, 252Y, 253I, 254S, 255G, 256T, 258L, 259V, 260V, 261D, 262A, 263S, 264Q, 265W
CDD
cd05369 (TER_DECR_SDR_a)

191G

homotetramer interface
85V, 116P, 117F, 118A, 120L, 121S, 122T, 125F, 126K, 129V, 133L, 134V, 137Y, 138N, 141K, 145E, 148R, 161L, 165G, 166T, 167P, 168L, 170S, 173C, 174A, 177A, 178G, 181A, 182L, 184N, 185N, 186L, 187A, 188I, 189E, 190L, 191G, 193L, 204A, 227I, 228P, 229L, 231A, 232M, 233G, 237D, 240E, 241G, 244F, 249A, 251K, 252Y, 253I, 254S, 255G, 256T, 258L, 259V, 260V, 261D, 262A, 263S, 264Q, 265W
CDD
cd05369 (TER_DECR_SDR_a)

193L

homotetramer interface
85V, 116P, 117F, 118A, 120L, 121S, 122T, 125F, 126K, 129V, 133L, 134V, 137Y, 138N, 141K, 145E, 148R, 161L, 165G, 166T, 167P, 168L, 170S, 173C, 174A, 177A, 178G, 181A, 182L, 184N, 185N, 186L, 187A, 188I, 189E, 190L, 191G, 193L, 204A, 227I, 228P, 229L, 231A, 232M, 233G, 237D, 240E, 241G, 244F, 249A, 251K, 252Y, 253I, 254S, 255G, 256T, 258L, 259V, 260V, 261D, 262A, 263S, 264Q, 265W
CDD
cd05369 (TER_DECR_SDR_a)

204A

homotetramer interface
85V, 116P, 117F, 118A, 120L, 121S, 122T, 125F, 126K, 129V, 133L, 134V, 137Y, 138N, 141K, 145E, 148R, 161L, 165G, 166T, 167P, 168L, 170S, 173C, 174A, 177A, 178G, 181A, 182L, 184N, 185N, 186L, 187A, 188I, 189E, 190L, 191G, 193L, 204A, 227I, 228P, 229L, 231A, 232M, 233G, 237D, 240E, 241G, 244F, 249A, 251K, 252Y, 253I, 254S, 255G, 256T, 258L, 259V, 260V, 261D, 262A, 263S, 264Q, 265W
CDD
cd05369 (TER_DECR_SDR_a)

227I

homotetramer interface
85V, 116P, 117F, 118A, 120L, 121S, 122T, 125F, 126K, 129V, 133L, 134V, 137Y, 138N, 141K, 145E, 148R, 161L, 165G, 166T, 167P, 168L, 170S, 173C, 174A, 177A, 178G, 181A, 182L, 184N, 185N, 186L, 187A, 188I, 189E, 190L, 191G, 193L, 204A, 227I, 228P, 229L, 231A, 232M, 233G, 237D, 240E, 241G, 244F, 249A, 251K, 252Y, 253I, 254S, 255G, 256T, 258L, 259V, 260V, 261D, 262A, 263S, 264Q, 265W
CDD
cd05369 (TER_DECR_SDR_a)

228P

homotetramer interface
85V, 116P, 117F, 118A, 120L, 121S, 122T, 125F, 126K, 129V, 133L, 134V, 137Y, 138N, 141K, 145E, 148R, 161L, 165G, 166T, 167P, 168L, 170S, 173C, 174A, 177A, 178G, 181A, 182L, 184N, 185N, 186L, 187A, 188I, 189E, 190L, 191G, 193L, 204A, 227I, 228P, 229L, 231A, 232M, 233G, 237D, 240E, 241G, 244F, 249A, 251K, 252Y, 253I, 254S, 255G, 256T, 258L, 259V, 260V, 261D, 262A, 263S, 264Q, 265W
CDD
cd05369 (TER_DECR_SDR_a)

229L

homotetramer interface
85V, 116P, 117F, 118A, 120L, 121S, 122T, 125F, 126K, 129V, 133L, 134V, 137Y, 138N, 141K, 145E, 148R, 161L, 165G, 166T, 167P, 168L, 170S, 173C, 174A, 177A, 178G, 181A, 182L, 184N, 185N, 186L, 187A, 188I, 189E, 190L, 191G, 193L, 204A, 227I, 228P, 229L, 231A, 232M, 233G, 237D, 240E, 241G, 244F, 249A, 251K, 252Y, 253I, 254S, 255G, 256T, 258L, 259V, 260V, 261D, 262A, 263S, 264Q, 265W
CDD
cd05369 (TER_DECR_SDR_a)

231A

homotetramer interface
85V, 116P, 117F, 118A, 120L, 121S, 122T, 125F, 126K, 129V, 133L, 134V, 137Y, 138N, 141K, 145E, 148R, 161L, 165G, 166T, 167P, 168L, 170S, 173C, 174A, 177A, 178G, 181A, 182L, 184N, 185N, 186L, 187A, 188I, 189E, 190L, 191G, 193L, 204A, 227I, 228P, 229L, 231A, 232M, 233G, 237D, 240E, 241G, 244F, 249A, 251K, 252Y, 253I, 254S, 255G, 256T, 258L, 259V, 260V, 261D, 262A, 263S, 264Q, 265W
CDD
cd05369 (TER_DECR_SDR_a)

232M

homotetramer interface
85V, 116P, 117F, 118A, 120L, 121S, 122T, 125F, 126K, 129V, 133L, 134V, 137Y, 138N, 141K, 145E, 148R, 161L, 165G, 166T, 167P, 168L, 170S, 173C, 174A, 177A, 178G, 181A, 182L, 184N, 185N, 186L, 187A, 188I, 189E, 190L, 191G, 193L, 204A, 227I, 228P, 229L, 231A, 232M, 233G, 237D, 240E, 241G, 244F, 249A, 251K, 252Y, 253I, 254S, 255G, 256T, 258L, 259V, 260V, 261D, 262A, 263S, 264Q, 265W
CDD
cd05369 (TER_DECR_SDR_a)

233G

homotetramer interface
85V, 116P, 117F, 118A, 120L, 121S, 122T, 125F, 126K, 129V, 133L, 134V, 137Y, 138N, 141K, 145E, 148R, 161L, 165G, 166T, 167P, 168L, 170S, 173C, 174A, 177A, 178G, 181A, 182L, 184N, 185N, 186L, 187A, 188I, 189E, 190L, 191G, 193L, 204A, 227I, 228P, 229L, 231A, 232M, 233G, 237D, 240E, 241G, 244F, 249A, 251K, 252Y, 253I, 254S, 255G, 256T, 258L, 259V, 260V, 261D, 262A, 263S, 264Q, 265W
CDD
cd05369 (TER_DECR_SDR_a)

237D

homotetramer interface
85V, 116P, 117F, 118A, 120L, 121S, 122T, 125F, 126K, 129V, 133L, 134V, 137Y, 138N, 141K, 145E, 148R, 161L, 165G, 166T, 167P, 168L, 170S, 173C, 174A, 177A, 178G, 181A, 182L, 184N, 185N, 186L, 187A, 188I, 189E, 190L, 191G, 193L, 204A, 227I, 228P, 229L, 231A, 232M, 233G, 237D, 240E, 241G, 244F, 249A, 251K, 252Y, 253I, 254S, 255G, 256T, 258L, 259V, 260V, 261D, 262A, 263S, 264Q, 265W
CDD
cd05369 (TER_DECR_SDR_a)

240E

homotetramer interface
85V, 116P, 117F, 118A, 120L, 121S, 122T, 125F, 126K, 129V, 133L, 134V, 137Y, 138N, 141K, 145E, 148R, 161L, 165G, 166T, 167P, 168L, 170S, 173C, 174A, 177A, 178G, 181A, 182L, 184N, 185N, 186L, 187A, 188I, 189E, 190L, 191G, 193L, 204A, 227I, 228P, 229L, 231A, 232M, 233G, 237D, 240E, 241G, 244F, 249A, 251K, 252Y, 253I, 254S, 255G, 256T, 258L, 259V, 260V, 261D, 262A, 263S, 264Q, 265W
CDD
cd05369 (TER_DECR_SDR_a)

241G

homotetramer interface
85V, 116P, 117F, 118A, 120L, 121S, 122T, 125F, 126K, 129V, 133L, 134V, 137Y, 138N, 141K, 145E, 148R, 161L, 165G, 166T, 167P, 168L, 170S, 173C, 174A, 177A, 178G, 181A, 182L, 184N, 185N, 186L, 187A, 188I, 189E, 190L, 191G, 193L, 204A, 227I, 228P, 229L, 231A, 232M, 233G, 237D, 240E, 241G, 244F, 249A, 251K, 252Y, 253I, 254S, 255G, 256T, 258L, 259V, 260V, 261D, 262A, 263S, 264Q, 265W
CDD
cd05369 (TER_DECR_SDR_a)

244F

homotetramer interface
85V, 116P, 117F, 118A, 120L, 121S, 122T, 125F, 126K, 129V, 133L, 134V, 137Y, 138N, 141K, 145E, 148R, 161L, 165G, 166T, 167P, 168L, 170S, 173C, 174A, 177A, 178G, 181A, 182L, 184N, 185N, 186L, 187A, 188I, 189E, 190L, 191G, 193L, 204A, 227I, 228P, 229L, 231A, 232M, 233G, 237D, 240E, 241G, 244F, 249A, 251K, 252Y, 253I, 254S, 255G, 256T, 258L, 259V, 260V, 261D, 262A, 263S, 264Q, 265W
CDD
cd05369 (TER_DECR_SDR_a)

249A

homotetramer interface
85V, 116P, 117F, 118A, 120L, 121S, 122T, 125F, 126K, 129V, 133L, 134V, 137Y, 138N, 141K, 145E, 148R, 161L, 165G, 166T, 167P, 168L, 170S, 173C, 174A, 177A, 178G, 181A, 182L, 184N, 185N, 186L, 187A, 188I, 189E, 190L, 191G, 193L, 204A, 227I, 228P, 229L, 231A, 232M, 233G, 237D, 240E, 241G, 244F, 249A, 251K, 252Y, 253I, 254S, 255G, 256T, 258L, 259V, 260V, 261D, 262A, 263S, 264Q, 265W
CDD
cd05369 (TER_DECR_SDR_a)

251K

homotetramer interface
85V, 116P, 117F, 118A, 120L, 121S, 122T, 125F, 126K, 129V, 133L, 134V, 137Y, 138N, 141K, 145E, 148R, 161L, 165G, 166T, 167P, 168L, 170S, 173C, 174A, 177A, 178G, 181A, 182L, 184N, 185N, 186L, 187A, 188I, 189E, 190L, 191G, 193L, 204A, 227I, 228P, 229L, 231A, 232M, 233G, 237D, 240E, 241G, 244F, 249A, 251K, 252Y, 253I, 254S, 255G, 256T, 258L, 259V, 260V, 261D, 262A, 263S, 264Q, 265W
CDD
cd05369 (TER_DECR_SDR_a)

252Y

homotetramer interface
85V, 116P, 117F, 118A, 120L, 121S, 122T, 125F, 126K, 129V, 133L, 134V, 137Y, 138N, 141K, 145E, 148R, 161L, 165G, 166T, 167P, 168L, 170S, 173C, 174A, 177A, 178G, 181A, 182L, 184N, 185N, 186L, 187A, 188I, 189E, 190L, 191G, 193L, 204A, 227I, 228P, 229L, 231A, 232M, 233G, 237D, 240E, 241G, 244F, 249A, 251K, 252Y, 253I, 254S, 255G, 256T, 258L, 259V, 260V, 261D, 262A, 263S, 264Q, 265W
CDD
cd05369 (TER_DECR_SDR_a)

253I

homotetramer interface
85V, 116P, 117F, 118A, 120L, 121S, 122T, 125F, 126K, 129V, 133L, 134V, 137Y, 138N, 141K, 145E, 148R, 161L, 165G, 166T, 167P, 168L, 170S, 173C, 174A, 177A, 178G, 181A, 182L, 184N, 185N, 186L, 187A, 188I, 189E, 190L, 191G, 193L, 204A, 227I, 228P, 229L, 231A, 232M, 233G, 237D, 240E, 241G, 244F, 249A, 251K, 252Y, 253I, 254S, 255G, 256T, 258L, 259V, 260V, 261D, 262A, 263S, 264Q, 265W
CDD
cd05369 (TER_DECR_SDR_a)

254S

homotetramer interface
85V, 116P, 117F, 118A, 120L, 121S, 122T, 125F, 126K, 129V, 133L, 134V, 137Y, 138N, 141K, 145E, 148R, 161L, 165G, 166T, 167P, 168L, 170S, 173C, 174A, 177A, 178G, 181A, 182L, 184N, 185N, 186L, 187A, 188I, 189E, 190L, 191G, 193L, 204A, 227I, 228P, 229L, 231A, 232M, 233G, 237D, 240E, 241G, 244F, 249A, 251K, 252Y, 253I, 254S, 255G, 256T, 258L, 259V, 260V, 261D, 262A, 263S, 264Q, 265W
CDD
cd05369 (TER_DECR_SDR_a)

255G

homotetramer interface
85V, 116P, 117F, 118A, 120L, 121S, 122T, 125F, 126K, 129V, 133L, 134V, 137Y, 138N, 141K, 145E, 148R, 161L, 165G, 166T, 167P, 168L, 170S, 173C, 174A, 177A, 178G, 181A, 182L, 184N, 185N, 186L, 187A, 188I, 189E, 190L, 191G, 193L, 204A, 227I, 228P, 229L, 231A, 232M, 233G, 237D, 240E, 241G, 244F, 249A, 251K, 252Y, 253I, 254S, 255G, 256T, 258L, 259V, 260V, 261D, 262A, 263S, 264Q, 265W
CDD
cd05369 (TER_DECR_SDR_a)

256T

homotetramer interface
85V, 116P, 117F, 118A, 120L, 121S, 122T, 125F, 126K, 129V, 133L, 134V, 137Y, 138N, 141K, 145E, 148R, 161L, 165G, 166T, 167P, 168L, 170S, 173C, 174A, 177A, 178G, 181A, 182L, 184N, 185N, 186L, 187A, 188I, 189E, 190L, 191G, 193L, 204A, 227I, 228P, 229L, 231A, 232M, 233G, 237D, 240E, 241G, 244F, 249A, 251K, 252Y, 253I, 254S, 255G, 256T, 258L, 259V, 260V, 261D, 262A, 263S, 264Q, 265W
CDD
cd05369 (TER_DECR_SDR_a)

258L

homotetramer interface
85V, 116P, 117F, 118A, 120L, 121S, 122T, 125F, 126K, 129V, 133L, 134V, 137Y, 138N, 141K, 145E, 148R, 161L, 165G, 166T, 167P, 168L, 170S, 173C, 174A, 177A, 178G, 181A, 182L, 184N, 185N, 186L, 187A, 188I, 189E, 190L, 191G, 193L, 204A, 227I, 228P, 229L, 231A, 232M, 233G, 237D, 240E, 241G, 244F, 249A, 251K, 252Y, 253I, 254S, 255G, 256T, 258L, 259V, 260V, 261D, 262A, 263S, 264Q, 265W
CDD
cd05369 (TER_DECR_SDR_a)

259V

homotetramer interface
85V, 116P, 117F, 118A, 120L, 121S, 122T, 125F, 126K, 129V, 133L, 134V, 137Y, 138N, 141K, 145E, 148R, 161L, 165G, 166T, 167P, 168L, 170S, 173C, 174A, 177A, 178G, 181A, 182L, 184N, 185N, 186L, 187A, 188I, 189E, 190L, 191G, 193L, 204A, 227I, 228P, 229L, 231A, 232M, 233G, 237D, 240E, 241G, 244F, 249A, 251K, 252Y, 253I, 254S, 255G, 256T, 258L, 259V, 260V, 261D, 262A, 263S, 264Q, 265W
CDD
cd05369 (TER_DECR_SDR_a)

260V

homotetramer interface
85V, 116P, 117F, 118A, 120L, 121S, 122T, 125F, 126K, 129V, 133L, 134V, 137Y, 138N, 141K, 145E, 148R, 161L, 165G, 166T, 167P, 168L, 170S, 173C, 174A, 177A, 178G, 181A, 182L, 184N, 185N, 186L, 187A, 188I, 189E, 190L, 191G, 193L, 204A, 227I, 228P, 229L, 231A, 232M, 233G, 237D, 240E, 241G, 244F, 249A, 251K, 252Y, 253I, 254S, 255G, 256T, 258L, 259V, 260V, 261D, 262A, 263S, 264Q, 265W
CDD
cd05369 (TER_DECR_SDR_a)

261D

homotetramer interface
85V, 116P, 117F, 118A, 120L, 121S, 122T, 125F, 126K, 129V, 133L, 134V, 137Y, 138N, 141K, 145E, 148R, 161L, 165G, 166T, 167P, 168L, 170S, 173C, 174A, 177A, 178G, 181A, 182L, 184N, 185N, 186L, 187A, 188I, 189E, 190L, 191G, 193L, 204A, 227I, 228P, 229L, 231A, 232M, 233G, 237D, 240E, 241G, 244F, 249A, 251K, 252Y, 253I, 254S, 255G, 256T, 258L, 259V, 260V, 261D, 262A, 263S, 264Q, 265W
CDD
cd05369 (TER_DECR_SDR_a)

262A

homotetramer interface
85V, 116P, 117F, 118A, 120L, 121S, 122T, 125F, 126K, 129V, 133L, 134V, 137Y, 138N, 141K, 145E, 148R, 161L, 165G, 166T, 167P, 168L, 170S, 173C, 174A, 177A, 178G, 181A, 182L, 184N, 185N, 186L, 187A, 188I, 189E, 190L, 191G, 193L, 204A, 227I, 228P, 229L, 231A, 232M, 233G, 237D, 240E, 241G, 244F, 249A, 251K, 252Y, 253I, 254S, 255G, 256T, 258L, 259V, 260V, 261D, 262A, 263S, 264Q, 265W
CDD
cd05369 (TER_DECR_SDR_a)

263S

homotetramer interface
85V, 116P, 117F, 118A, 120L, 121S, 122T, 125F, 126K, 129V, 133L, 134V, 137Y, 138N, 141K, 145E, 148R, 161L, 165G, 166T, 167P, 168L, 170S, 173C, 174A, 177A, 178G, 181A, 182L, 184N, 185N, 186L, 187A, 188I, 189E, 190L, 191G, 193L, 204A, 227I, 228P, 229L, 231A, 232M, 233G, 237D, 240E, 241G, 244F, 249A, 251K, 252Y, 253I, 254S, 255G, 256T, 258L, 259V, 260V, 261D, 262A, 263S, 264Q, 265W
CDD
cd05369 (TER_DECR_SDR_a)

264Q

homotetramer interface
85V, 116P, 117F, 118A, 120L, 121S, 122T, 125F, 126K, 129V, 133L, 134V, 137Y, 138N, 141K, 145E, 148R, 161L, 165G, 166T, 167P, 168L, 170S, 173C, 174A, 177A, 178G, 181A, 182L, 184N, 185N, 186L, 187A, 188I, 189E, 190L, 191G, 193L, 204A, 227I, 228P, 229L, 231A, 232M, 233G, 237D, 240E, 241G, 244F, 249A, 251K, 252Y, 253I, 254S, 255G, 256T, 258L, 259V, 260V, 261D, 262A, 263S, 264Q, 265W
CDD
cd05369 (TER_DECR_SDR_a)

265W

homotetramer interface
85V, 116P, 117F, 118A, 120L, 121S, 122T, 125F, 126K, 129V, 133L, 134V, 137Y, 138N, 141K, 145E, 148R, 161L, 165G, 166T, 167P, 168L, 170S, 173C, 174A, 177A, 178G, 181A, 182L, 184N, 185N, 186L, 187A, 188I, 189E, 190L, 191G, 193L, 204A, 227I, 228P, 229L, 231A, 232M, 233G, 237D, 240E, 241G, 244F, 249A, 251K, 252Y, 253I, 254S, 255G, 256T, 258L, 259V, 260V, 261D, 262A, 263S, 264Q, 265W
CDD
cd05369 (TER_DECR_SDR_a)
active site cd05369

112N

active site
112N, 161L, 172A, 176K
CDD
cd05369 (TER_DECR_SDR_a)

161L

active site
112N, 161L, 172A, 176K
CDD
cd05369 (TER_DECR_SDR_a)

172A

active site
112N, 161L, 172A, 176K
CDD
cd05369 (TER_DECR_SDR_a)

176K

active site
112N, 161L, 172A, 176K
CDD
cd05369 (TER_DECR_SDR_a)
homodimer interfac...

116P

homodimer interface
116P, 117F, 118A, 120L, 125F, 126K, 129V, 134V, 137Y, 138N, 165G, 166T, 167P, 168L, 170S, 173C, 174A, 177A, 178G, 181A, 182L, 185N, 188I, 189E
CDD
cd05369 (TER_DECR_SDR_a)

117F

homodimer interface
116P, 117F, 118A, 120L, 125F, 126K, 129V, 134V, 137Y, 138N, 165G, 166T, 167P, 168L, 170S, 173C, 174A, 177A, 178G, 181A, 182L, 185N, 188I, 189E
CDD
cd05369 (TER_DECR_SDR_a)

118A

homodimer interface
116P, 117F, 118A, 120L, 125F, 126K, 129V, 134V, 137Y, 138N, 165G, 166T, 167P, 168L, 170S, 173C, 174A, 177A, 178G, 181A, 182L, 185N, 188I, 189E
CDD
cd05369 (TER_DECR_SDR_a)

120L

homodimer interface
116P, 117F, 118A, 120L, 125F, 126K, 129V, 134V, 137Y, 138N, 165G, 166T, 167P, 168L, 170S, 173C, 174A, 177A, 178G, 181A, 182L, 185N, 188I, 189E
CDD
cd05369 (TER_DECR_SDR_a)

125F

homodimer interface
116P, 117F, 118A, 120L, 125F, 126K, 129V, 134V, 137Y, 138N, 165G, 166T, 167P, 168L, 170S, 173C, 174A, 177A, 178G, 181A, 182L, 185N, 188I, 189E
CDD
cd05369 (TER_DECR_SDR_a)

126K

homodimer interface
116P, 117F, 118A, 120L, 125F, 126K, 129V, 134V, 137Y, 138N, 165G, 166T, 167P, 168L, 170S, 173C, 174A, 177A, 178G, 181A, 182L, 185N, 188I, 189E
CDD
cd05369 (TER_DECR_SDR_a)

129V

homodimer interface
116P, 117F, 118A, 120L, 125F, 126K, 129V, 134V, 137Y, 138N, 165G, 166T, 167P, 168L, 170S, 173C, 174A, 177A, 178G, 181A, 182L, 185N, 188I, 189E
CDD
cd05369 (TER_DECR_SDR_a)

134V

homodimer interface
116P, 117F, 118A, 120L, 125F, 126K, 129V, 134V, 137Y, 138N, 165G, 166T, 167P, 168L, 170S, 173C, 174A, 177A, 178G, 181A, 182L, 185N, 188I, 189E
CDD
cd05369 (TER_DECR_SDR_a)

137Y

homodimer interface
116P, 117F, 118A, 120L, 125F, 126K, 129V, 134V, 137Y, 138N, 165G, 166T, 167P, 168L, 170S, 173C, 174A, 177A, 178G, 181A, 182L, 185N, 188I, 189E
CDD
cd05369 (TER_DECR_SDR_a)

138N

homodimer interface
116P, 117F, 118A, 120L, 125F, 126K, 129V, 134V, 137Y, 138N, 165G, 166T, 167P, 168L, 170S, 173C, 174A, 177A, 178G, 181A, 182L, 185N, 188I, 189E
CDD
cd05369 (TER_DECR_SDR_a)

165G

homodimer interface
116P, 117F, 118A, 120L, 125F, 126K, 129V, 134V, 137Y, 138N, 165G, 166T, 167P, 168L, 170S, 173C, 174A, 177A, 178G, 181A, 182L, 185N, 188I, 189E
CDD
cd05369 (TER_DECR_SDR_a)

166T

homodimer interface
116P, 117F, 118A, 120L, 125F, 126K, 129V, 134V, 137Y, 138N, 165G, 166T, 167P, 168L, 170S, 173C, 174A, 177A, 178G, 181A, 182L, 185N, 188I, 189E
CDD
cd05369 (TER_DECR_SDR_a)

167P

homodimer interface
116P, 117F, 118A, 120L, 125F, 126K, 129V, 134V, 137Y, 138N, 165G, 166T, 167P, 168L, 170S, 173C, 174A, 177A, 178G, 181A, 182L, 185N, 188I, 189E
CDD
cd05369 (TER_DECR_SDR_a)

168L

homodimer interface
116P, 117F, 118A, 120L, 125F, 126K, 129V, 134V, 137Y, 138N, 165G, 166T, 167P, 168L, 170S, 173C, 174A, 177A, 178G, 181A, 182L, 185N, 188I, 189E
CDD
cd05369 (TER_DECR_SDR_a)

170S

homodimer interface
116P, 117F, 118A, 120L, 125F, 126K, 129V, 134V, 137Y, 138N, 165G, 166T, 167P, 168L, 170S, 173C, 174A, 177A, 178G, 181A, 182L, 185N, 188I, 189E
CDD
cd05369 (TER_DECR_SDR_a)

173C

homodimer interface
116P, 117F, 118A, 120L, 125F, 126K, 129V, 134V, 137Y, 138N, 165G, 166T, 167P, 168L, 170S, 173C, 174A, 177A, 178G, 181A, 182L, 185N, 188I, 189E
CDD
cd05369 (TER_DECR_SDR_a)

174A

homodimer interface
116P, 117F, 118A, 120L, 125F, 126K, 129V, 134V, 137Y, 138N, 165G, 166T, 167P, 168L, 170S, 173C, 174A, 177A, 178G, 181A, 182L, 185N, 188I, 189E
CDD
cd05369 (TER_DECR_SDR_a)

177A

homodimer interface
116P, 117F, 118A, 120L, 125F, 126K, 129V, 134V, 137Y, 138N, 165G, 166T, 167P, 168L, 170S, 173C, 174A, 177A, 178G, 181A, 182L, 185N, 188I, 189E
CDD
cd05369 (TER_DECR_SDR_a)

178G

homodimer interface
116P, 117F, 118A, 120L, 125F, 126K, 129V, 134V, 137Y, 138N, 165G, 166T, 167P, 168L, 170S, 173C, 174A, 177A, 178G, 181A, 182L, 185N, 188I, 189E
CDD
cd05369 (TER_DECR_SDR_a)

181A

homodimer interface
116P, 117F, 118A, 120L, 125F, 126K, 129V, 134V, 137Y, 138N, 165G, 166T, 167P, 168L, 170S, 173C, 174A, 177A, 178G, 181A, 182L, 185N, 188I, 189E
CDD
cd05369 (TER_DECR_SDR_a)

182L

homodimer interface
116P, 117F, 118A, 120L, 125F, 126K, 129V, 134V, 137Y, 138N, 165G, 166T, 167P, 168L, 170S, 173C, 174A, 177A, 178G, 181A, 182L, 185N, 188I, 189E
CDD
cd05369 (TER_DECR_SDR_a)

185N

homodimer interface
116P, 117F, 118A, 120L, 125F, 126K, 129V, 134V, 137Y, 138N, 165G, 166T, 167P, 168L, 170S, 173C, 174A, 177A, 178G, 181A, 182L, 185N, 188I, 189E
CDD
cd05369 (TER_DECR_SDR_a)

188I

homodimer interface
116P, 117F, 118A, 120L, 125F, 126K, 129V, 134V, 137Y, 138N, 165G, 166T, 167P, 168L, 170S, 173C, 174A, 177A, 178G, 181A, 182L, 185N, 188I, 189E
CDD
cd05369 (TER_DECR_SDR_a)

189E

homodimer interface
116P, 117F, 118A, 120L, 125F, 126K, 129V, 134V, 137Y, 138N, 165G, 166T, 167P, 168L, 170S, 173C, 174A, 177A, 178G, 181A, 182L, 185N, 188I, 189E
CDD
cd05369 (TER_DECR_SDR_a)

Protein sequence

>MIA_03268_1
MTSLDKSFLDTSVWKKDIFKGKVAFITGGAGTIGRVQSQALVLLGADVAIIGRRVEATEKAAEEIAKLRPGAKVIGIGGV
DVRSVPSLEKAVERTLRELGRIDFVIAGAAGNFLAPFAGLSTNAFKTVVDIDLVGSYNTAKATFEAVRESKGVYLFISAG
LHYAGTPLQSHACAAKAGVDALSNNLAIELGPLGIRSNTICPGAIEGTEGMDRLVPKPELEEMVSKIPLGAMGKPQDIAE
GTVFLLSDAAKYISGTTLVVDASQWRMGNYAAIKTYPEALVSLNGGKNKL

GO term prediction

Biological Process

None predicted.

Molecular Function

None predicted.

Cellular Component

None predicted.

Filter view on

Entry type

Status

Per-residue features

MIA_03268_1

Protein function

Protein alignments

Mitochondrial localization by mitoprotII

Protein family membership

Domains and repeats

Detailed signature matches

Residue annotation

Protein sequence

GO term prediction

Biological Process

Molecular Function

Cellular Component