MCA_03583_1

Protein

Length

293 amino acids

RNA-seq: read pairs 970, FPKM 40.8, percentile rank 60.7% (100% = highest expression)

Protein function

KEGG:	K13237	DECR2	peroxisomal 2,4-dienoyl-CoA reductase [EC:1.3.1.34]
EGGNOG:	0PF95	FG00407.1	Sporulation protein SPS19
SGD closest match:	S000005146	SPS19	Peroxisomal 2,4-dienoyl-CoA reductase SPS19
CGD closest match:	CAL0000196598	SPS20	Sps20p

Protein alignments

	%id	Aln length	E-value
MIA_03268_1	69.05%	294	1e-131	MIA_03268_1
A0A0J9X4T4_GEOCN	61.64%	292	7e-116	Similar to Saccharomyces cerevisiae YNL202W SPS19 Peroxisomal 2,4-dienoyl-CoA reductase OS=Geotrichum candidum GN=BN980_GECA02s07259g PE=4 SV=1
Q59SL5_CANAL	60.14%	286	1e-112	Sps20p OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=SPS20 PE=4 SV=1
A0A167CBW1_9ASCO	58.64%	295	2e-112	Sps19p OS=Sugiyamaella lignohabitans GN=SPS19 PE=4 SV=1
Q6CD80_YARLI	56.46%	294	6e-105	YALI0C03003p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_C03003g PE=4 SV=1
A0A060T9V3_BLAAD	62.13%	272	2e-104	ARAD1D17534p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D17534g PE=4 SV=1
SPS19_YEAST	53.79%	290	2e-101	Peroxisomal 2,4-dienoyl-CoA reductase SPS19 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SPS19 PE=1 SV=4
UniRef50_P32573	53.79%	290	6e-98	Peroxisomal 2,4-dienoyl-CoA reductase SPS19 n=200 Tax=Fungi TaxID=4751 RepID=SPS19_YEAST
A0A1E3PH09_9ASCO	55.67%	300	2e-98	NAD(P)-binding protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_83599 PE=4 SV=1
A0A1E4TEX7_9ASCO	53.70%	270	2e-85	Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_25338 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0781

Protein family membership

Short-chain dehydrogenase/reductase SDR (IPR002347)

Domains and repeats

Domain
14 - 273
NAD(P)-binding domain (IPR016040)

1 50 100 150 200 250 293

Detailed signature matches

IPR002347

Short-chain dehydrogenase/reductase SDR
1. PR00081 (GDHRDH)
  
  232 - 252
  
  PRINTS
  PR00081 (GDHRDH)
  
  196 - 213
  
  PRINTS
  PR00081 (GDHRDH)
  
  175 - 194
  
  PRINTS
  PR00081 (GDHRDH)
  
  23 - 40
  
  PRINTS
  PR00081 (GDHRDH)
  
  103 - 114
  
  PRINTS
  PR00081 (GDHRDH)
IPR016040

NAD(P)-binding domain
1. SSF51735 (NAD(P)-bi...)
  
  14 - 273
  
  SUPERFAMILY
  SSF51735 (NAD(P)-binding Rossmann-fold domains)

no IPR

Unintegrated signatures

G3DSA:3.40.50...

5 - 292

GENE3D
G3DSA:3.40.50.720 (G3DSA:3.40.50.720)
PF13561 (adh_short_C2)

30 - 268

Pfam
PF13561 (adh_short_C2)
cd05369 (TER_DECR_S...)

19 - 269

CDD
cd05369 (TER_DECR_SDR_a)

Residue annotation

NAD(P) binding sit...

28G

NAD(P) binding site
28G, 31G, 32T, 33I, 52G, 53R, 54N, 83V, 84D, 85V, 86R, 111G, 112A, 113A, 134I, 160I, 161S, 162A, 179K, 205P, 206G, 207A, 208I, 210G
CDD
cd05369 (TER_DECR_SDR_a)

31G

NAD(P) binding site
28G, 31G, 32T, 33I, 52G, 53R, 54N, 83V, 84D, 85V, 86R, 111G, 112A, 113A, 134I, 160I, 161S, 162A, 179K, 205P, 206G, 207A, 208I, 210G
CDD
cd05369 (TER_DECR_SDR_a)

32T

NAD(P) binding site
28G, 31G, 32T, 33I, 52G, 53R, 54N, 83V, 84D, 85V, 86R, 111G, 112A, 113A, 134I, 160I, 161S, 162A, 179K, 205P, 206G, 207A, 208I, 210G
CDD
cd05369 (TER_DECR_SDR_a)

33I

NAD(P) binding site
28G, 31G, 32T, 33I, 52G, 53R, 54N, 83V, 84D, 85V, 86R, 111G, 112A, 113A, 134I, 160I, 161S, 162A, 179K, 205P, 206G, 207A, 208I, 210G
CDD
cd05369 (TER_DECR_SDR_a)

52G

NAD(P) binding site
28G, 31G, 32T, 33I, 52G, 53R, 54N, 83V, 84D, 85V, 86R, 111G, 112A, 113A, 134I, 160I, 161S, 162A, 179K, 205P, 206G, 207A, 208I, 210G
CDD
cd05369 (TER_DECR_SDR_a)

53R

NAD(P) binding site
28G, 31G, 32T, 33I, 52G, 53R, 54N, 83V, 84D, 85V, 86R, 111G, 112A, 113A, 134I, 160I, 161S, 162A, 179K, 205P, 206G, 207A, 208I, 210G
CDD
cd05369 (TER_DECR_SDR_a)

54N

NAD(P) binding site
28G, 31G, 32T, 33I, 52G, 53R, 54N, 83V, 84D, 85V, 86R, 111G, 112A, 113A, 134I, 160I, 161S, 162A, 179K, 205P, 206G, 207A, 208I, 210G
CDD
cd05369 (TER_DECR_SDR_a)

83V

NAD(P) binding site
28G, 31G, 32T, 33I, 52G, 53R, 54N, 83V, 84D, 85V, 86R, 111G, 112A, 113A, 134I, 160I, 161S, 162A, 179K, 205P, 206G, 207A, 208I, 210G
CDD
cd05369 (TER_DECR_SDR_a)

84D

NAD(P) binding site
28G, 31G, 32T, 33I, 52G, 53R, 54N, 83V, 84D, 85V, 86R, 111G, 112A, 113A, 134I, 160I, 161S, 162A, 179K, 205P, 206G, 207A, 208I, 210G
CDD
cd05369 (TER_DECR_SDR_a)

85V

NAD(P) binding site
28G, 31G, 32T, 33I, 52G, 53R, 54N, 83V, 84D, 85V, 86R, 111G, 112A, 113A, 134I, 160I, 161S, 162A, 179K, 205P, 206G, 207A, 208I, 210G
CDD
cd05369 (TER_DECR_SDR_a)

86R

NAD(P) binding site
28G, 31G, 32T, 33I, 52G, 53R, 54N, 83V, 84D, 85V, 86R, 111G, 112A, 113A, 134I, 160I, 161S, 162A, 179K, 205P, 206G, 207A, 208I, 210G
CDD
cd05369 (TER_DECR_SDR_a)

111G

NAD(P) binding site
28G, 31G, 32T, 33I, 52G, 53R, 54N, 83V, 84D, 85V, 86R, 111G, 112A, 113A, 134I, 160I, 161S, 162A, 179K, 205P, 206G, 207A, 208I, 210G
CDD
cd05369 (TER_DECR_SDR_a)

112A

NAD(P) binding site
28G, 31G, 32T, 33I, 52G, 53R, 54N, 83V, 84D, 85V, 86R, 111G, 112A, 113A, 134I, 160I, 161S, 162A, 179K, 205P, 206G, 207A, 208I, 210G
CDD
cd05369 (TER_DECR_SDR_a)

113A

NAD(P) binding site
28G, 31G, 32T, 33I, 52G, 53R, 54N, 83V, 84D, 85V, 86R, 111G, 112A, 113A, 134I, 160I, 161S, 162A, 179K, 205P, 206G, 207A, 208I, 210G
CDD
cd05369 (TER_DECR_SDR_a)

134I

NAD(P) binding site
28G, 31G, 32T, 33I, 52G, 53R, 54N, 83V, 84D, 85V, 86R, 111G, 112A, 113A, 134I, 160I, 161S, 162A, 179K, 205P, 206G, 207A, 208I, 210G
CDD
cd05369 (TER_DECR_SDR_a)

160I

NAD(P) binding site
28G, 31G, 32T, 33I, 52G, 53R, 54N, 83V, 84D, 85V, 86R, 111G, 112A, 113A, 134I, 160I, 161S, 162A, 179K, 205P, 206G, 207A, 208I, 210G
CDD
cd05369 (TER_DECR_SDR_a)

161S

NAD(P) binding site
28G, 31G, 32T, 33I, 52G, 53R, 54N, 83V, 84D, 85V, 86R, 111G, 112A, 113A, 134I, 160I, 161S, 162A, 179K, 205P, 206G, 207A, 208I, 210G
CDD
cd05369 (TER_DECR_SDR_a)

162A

NAD(P) binding site
28G, 31G, 32T, 33I, 52G, 53R, 54N, 83V, 84D, 85V, 86R, 111G, 112A, 113A, 134I, 160I, 161S, 162A, 179K, 205P, 206G, 207A, 208I, 210G
CDD
cd05369 (TER_DECR_SDR_a)

179K

NAD(P) binding site
28G, 31G, 32T, 33I, 52G, 53R, 54N, 83V, 84D, 85V, 86R, 111G, 112A, 113A, 134I, 160I, 161S, 162A, 179K, 205P, 206G, 207A, 208I, 210G
CDD
cd05369 (TER_DECR_SDR_a)

205P

NAD(P) binding site
28G, 31G, 32T, 33I, 52G, 53R, 54N, 83V, 84D, 85V, 86R, 111G, 112A, 113A, 134I, 160I, 161S, 162A, 179K, 205P, 206G, 207A, 208I, 210G
CDD
cd05369 (TER_DECR_SDR_a)

206G

NAD(P) binding site
28G, 31G, 32T, 33I, 52G, 53R, 54N, 83V, 84D, 85V, 86R, 111G, 112A, 113A, 134I, 160I, 161S, 162A, 179K, 205P, 206G, 207A, 208I, 210G
CDD
cd05369 (TER_DECR_SDR_a)

207A

NAD(P) binding site
28G, 31G, 32T, 33I, 52G, 53R, 54N, 83V, 84D, 85V, 86R, 111G, 112A, 113A, 134I, 160I, 161S, 162A, 179K, 205P, 206G, 207A, 208I, 210G
CDD
cd05369 (TER_DECR_SDR_a)

208I

NAD(P) binding site
28G, 31G, 32T, 33I, 52G, 53R, 54N, 83V, 84D, 85V, 86R, 111G, 112A, 113A, 134I, 160I, 161S, 162A, 179K, 205P, 206G, 207A, 208I, 210G
CDD
cd05369 (TER_DECR_SDR_a)

210G

NAD(P) binding site
28G, 31G, 32T, 33I, 52G, 53R, 54N, 83V, 84D, 85V, 86R, 111G, 112A, 113A, 134I, 160I, 161S, 162A, 179K, 205P, 206G, 207A, 208I, 210G
CDD
cd05369 (TER_DECR_SDR_a)
substrate binding ...

53R

substrate binding site
53R, 86R, 113A, 114G, 115N, 116F, 124S, 126N, 127A, 130T, 162A, 164L, 175A, 207A
CDD
cd05369 (TER_DECR_SDR_a)

86R

substrate binding site
53R, 86R, 113A, 114G, 115N, 116F, 124S, 126N, 127A, 130T, 162A, 164L, 175A, 207A
CDD
cd05369 (TER_DECR_SDR_a)

113A

substrate binding site
53R, 86R, 113A, 114G, 115N, 116F, 124S, 126N, 127A, 130T, 162A, 164L, 175A, 207A
CDD
cd05369 (TER_DECR_SDR_a)

114G

substrate binding site
53R, 86R, 113A, 114G, 115N, 116F, 124S, 126N, 127A, 130T, 162A, 164L, 175A, 207A
CDD
cd05369 (TER_DECR_SDR_a)

115N

substrate binding site
53R, 86R, 113A, 114G, 115N, 116F, 124S, 126N, 127A, 130T, 162A, 164L, 175A, 207A
CDD
cd05369 (TER_DECR_SDR_a)

116F

substrate binding site
53R, 86R, 113A, 114G, 115N, 116F, 124S, 126N, 127A, 130T, 162A, 164L, 175A, 207A
CDD
cd05369 (TER_DECR_SDR_a)

124S

substrate binding site
53R, 86R, 113A, 114G, 115N, 116F, 124S, 126N, 127A, 130T, 162A, 164L, 175A, 207A
CDD
cd05369 (TER_DECR_SDR_a)

126N

substrate binding site
53R, 86R, 113A, 114G, 115N, 116F, 124S, 126N, 127A, 130T, 162A, 164L, 175A, 207A
CDD
cd05369 (TER_DECR_SDR_a)

127A

substrate binding site
53R, 86R, 113A, 114G, 115N, 116F, 124S, 126N, 127A, 130T, 162A, 164L, 175A, 207A
CDD
cd05369 (TER_DECR_SDR_a)

130T

substrate binding site
53R, 86R, 113A, 114G, 115N, 116F, 124S, 126N, 127A, 130T, 162A, 164L, 175A, 207A
CDD
cd05369 (TER_DECR_SDR_a)

162A

substrate binding site
53R, 86R, 113A, 114G, 115N, 116F, 124S, 126N, 127A, 130T, 162A, 164L, 175A, 207A
CDD
cd05369 (TER_DECR_SDR_a)

164L

substrate binding site
53R, 86R, 113A, 114G, 115N, 116F, 124S, 126N, 127A, 130T, 162A, 164L, 175A, 207A
CDD
cd05369 (TER_DECR_SDR_a)

175A

substrate binding site
53R, 86R, 113A, 114G, 115N, 116F, 124S, 126N, 127A, 130T, 162A, 164L, 175A, 207A
CDD
cd05369 (TER_DECR_SDR_a)

207A

substrate binding site
53R, 86R, 113A, 114G, 115N, 116F, 124S, 126N, 127A, 130T, 162A, 164L, 175A, 207A
CDD
cd05369 (TER_DECR_SDR_a)
homotetramer inter...

88M

homotetramer interface
88M, 119N, 120F, 121A, 123L, 124S, 125S, 128F, 129R, 132V, 136L, 137I, 140Y, 141N, 144K, 148D, 151K, 164L, 168G, 169T, 170P, 171L, 173T, 176A, 177A, 180A, 181G, 184A, 185L, 187N, 188N, 189L, 190A, 191I, 192E, 193L, 194G, 196L, 207A, 231I, 232P, 233L, 235R, 236M, 237G, 241D, 244D, 245G, 248F, 253A, 255S, 256Y, 257V, 258S, 259G, 260T, 262L, 263V, 264V, 265D, 266A, 267G, 268L, 269W
CDD
cd05369 (TER_DECR_SDR_a)

119N

homotetramer interface
88M, 119N, 120F, 121A, 123L, 124S, 125S, 128F, 129R, 132V, 136L, 137I, 140Y, 141N, 144K, 148D, 151K, 164L, 168G, 169T, 170P, 171L, 173T, 176A, 177A, 180A, 181G, 184A, 185L, 187N, 188N, 189L, 190A, 191I, 192E, 193L, 194G, 196L, 207A, 231I, 232P, 233L, 235R, 236M, 237G, 241D, 244D, 245G, 248F, 253A, 255S, 256Y, 257V, 258S, 259G, 260T, 262L, 263V, 264V, 265D, 266A, 267G, 268L, 269W
CDD
cd05369 (TER_DECR_SDR_a)

120F

homotetramer interface
88M, 119N, 120F, 121A, 123L, 124S, 125S, 128F, 129R, 132V, 136L, 137I, 140Y, 141N, 144K, 148D, 151K, 164L, 168G, 169T, 170P, 171L, 173T, 176A, 177A, 180A, 181G, 184A, 185L, 187N, 188N, 189L, 190A, 191I, 192E, 193L, 194G, 196L, 207A, 231I, 232P, 233L, 235R, 236M, 237G, 241D, 244D, 245G, 248F, 253A, 255S, 256Y, 257V, 258S, 259G, 260T, 262L, 263V, 264V, 265D, 266A, 267G, 268L, 269W
CDD
cd05369 (TER_DECR_SDR_a)

121A

homotetramer interface
88M, 119N, 120F, 121A, 123L, 124S, 125S, 128F, 129R, 132V, 136L, 137I, 140Y, 141N, 144K, 148D, 151K, 164L, 168G, 169T, 170P, 171L, 173T, 176A, 177A, 180A, 181G, 184A, 185L, 187N, 188N, 189L, 190A, 191I, 192E, 193L, 194G, 196L, 207A, 231I, 232P, 233L, 235R, 236M, 237G, 241D, 244D, 245G, 248F, 253A, 255S, 256Y, 257V, 258S, 259G, 260T, 262L, 263V, 264V, 265D, 266A, 267G, 268L, 269W
CDD
cd05369 (TER_DECR_SDR_a)

123L

homotetramer interface
88M, 119N, 120F, 121A, 123L, 124S, 125S, 128F, 129R, 132V, 136L, 137I, 140Y, 141N, 144K, 148D, 151K, 164L, 168G, 169T, 170P, 171L, 173T, 176A, 177A, 180A, 181G, 184A, 185L, 187N, 188N, 189L, 190A, 191I, 192E, 193L, 194G, 196L, 207A, 231I, 232P, 233L, 235R, 236M, 237G, 241D, 244D, 245G, 248F, 253A, 255S, 256Y, 257V, 258S, 259G, 260T, 262L, 263V, 264V, 265D, 266A, 267G, 268L, 269W
CDD
cd05369 (TER_DECR_SDR_a)

124S

homotetramer interface
88M, 119N, 120F, 121A, 123L, 124S, 125S, 128F, 129R, 132V, 136L, 137I, 140Y, 141N, 144K, 148D, 151K, 164L, 168G, 169T, 170P, 171L, 173T, 176A, 177A, 180A, 181G, 184A, 185L, 187N, 188N, 189L, 190A, 191I, 192E, 193L, 194G, 196L, 207A, 231I, 232P, 233L, 235R, 236M, 237G, 241D, 244D, 245G, 248F, 253A, 255S, 256Y, 257V, 258S, 259G, 260T, 262L, 263V, 264V, 265D, 266A, 267G, 268L, 269W
CDD
cd05369 (TER_DECR_SDR_a)

125S

homotetramer interface
88M, 119N, 120F, 121A, 123L, 124S, 125S, 128F, 129R, 132V, 136L, 137I, 140Y, 141N, 144K, 148D, 151K, 164L, 168G, 169T, 170P, 171L, 173T, 176A, 177A, 180A, 181G, 184A, 185L, 187N, 188N, 189L, 190A, 191I, 192E, 193L, 194G, 196L, 207A, 231I, 232P, 233L, 235R, 236M, 237G, 241D, 244D, 245G, 248F, 253A, 255S, 256Y, 257V, 258S, 259G, 260T, 262L, 263V, 264V, 265D, 266A, 267G, 268L, 269W
CDD
cd05369 (TER_DECR_SDR_a)

128F

homotetramer interface
88M, 119N, 120F, 121A, 123L, 124S, 125S, 128F, 129R, 132V, 136L, 137I, 140Y, 141N, 144K, 148D, 151K, 164L, 168G, 169T, 170P, 171L, 173T, 176A, 177A, 180A, 181G, 184A, 185L, 187N, 188N, 189L, 190A, 191I, 192E, 193L, 194G, 196L, 207A, 231I, 232P, 233L, 235R, 236M, 237G, 241D, 244D, 245G, 248F, 253A, 255S, 256Y, 257V, 258S, 259G, 260T, 262L, 263V, 264V, 265D, 266A, 267G, 268L, 269W
CDD
cd05369 (TER_DECR_SDR_a)

129R

homotetramer interface
88M, 119N, 120F, 121A, 123L, 124S, 125S, 128F, 129R, 132V, 136L, 137I, 140Y, 141N, 144K, 148D, 151K, 164L, 168G, 169T, 170P, 171L, 173T, 176A, 177A, 180A, 181G, 184A, 185L, 187N, 188N, 189L, 190A, 191I, 192E, 193L, 194G, 196L, 207A, 231I, 232P, 233L, 235R, 236M, 237G, 241D, 244D, 245G, 248F, 253A, 255S, 256Y, 257V, 258S, 259G, 260T, 262L, 263V, 264V, 265D, 266A, 267G, 268L, 269W
CDD
cd05369 (TER_DECR_SDR_a)

132V

homotetramer interface
88M, 119N, 120F, 121A, 123L, 124S, 125S, 128F, 129R, 132V, 136L, 137I, 140Y, 141N, 144K, 148D, 151K, 164L, 168G, 169T, 170P, 171L, 173T, 176A, 177A, 180A, 181G, 184A, 185L, 187N, 188N, 189L, 190A, 191I, 192E, 193L, 194G, 196L, 207A, 231I, 232P, 233L, 235R, 236M, 237G, 241D, 244D, 245G, 248F, 253A, 255S, 256Y, 257V, 258S, 259G, 260T, 262L, 263V, 264V, 265D, 266A, 267G, 268L, 269W
CDD
cd05369 (TER_DECR_SDR_a)

136L

homotetramer interface
88M, 119N, 120F, 121A, 123L, 124S, 125S, 128F, 129R, 132V, 136L, 137I, 140Y, 141N, 144K, 148D, 151K, 164L, 168G, 169T, 170P, 171L, 173T, 176A, 177A, 180A, 181G, 184A, 185L, 187N, 188N, 189L, 190A, 191I, 192E, 193L, 194G, 196L, 207A, 231I, 232P, 233L, 235R, 236M, 237G, 241D, 244D, 245G, 248F, 253A, 255S, 256Y, 257V, 258S, 259G, 260T, 262L, 263V, 264V, 265D, 266A, 267G, 268L, 269W
CDD
cd05369 (TER_DECR_SDR_a)

137I

homotetramer interface
88M, 119N, 120F, 121A, 123L, 124S, 125S, 128F, 129R, 132V, 136L, 137I, 140Y, 141N, 144K, 148D, 151K, 164L, 168G, 169T, 170P, 171L, 173T, 176A, 177A, 180A, 181G, 184A, 185L, 187N, 188N, 189L, 190A, 191I, 192E, 193L, 194G, 196L, 207A, 231I, 232P, 233L, 235R, 236M, 237G, 241D, 244D, 245G, 248F, 253A, 255S, 256Y, 257V, 258S, 259G, 260T, 262L, 263V, 264V, 265D, 266A, 267G, 268L, 269W
CDD
cd05369 (TER_DECR_SDR_a)

140Y

homotetramer interface
88M, 119N, 120F, 121A, 123L, 124S, 125S, 128F, 129R, 132V, 136L, 137I, 140Y, 141N, 144K, 148D, 151K, 164L, 168G, 169T, 170P, 171L, 173T, 176A, 177A, 180A, 181G, 184A, 185L, 187N, 188N, 189L, 190A, 191I, 192E, 193L, 194G, 196L, 207A, 231I, 232P, 233L, 235R, 236M, 237G, 241D, 244D, 245G, 248F, 253A, 255S, 256Y, 257V, 258S, 259G, 260T, 262L, 263V, 264V, 265D, 266A, 267G, 268L, 269W
CDD
cd05369 (TER_DECR_SDR_a)

141N

homotetramer interface
88M, 119N, 120F, 121A, 123L, 124S, 125S, 128F, 129R, 132V, 136L, 137I, 140Y, 141N, 144K, 148D, 151K, 164L, 168G, 169T, 170P, 171L, 173T, 176A, 177A, 180A, 181G, 184A, 185L, 187N, 188N, 189L, 190A, 191I, 192E, 193L, 194G, 196L, 207A, 231I, 232P, 233L, 235R, 236M, 237G, 241D, 244D, 245G, 248F, 253A, 255S, 256Y, 257V, 258S, 259G, 260T, 262L, 263V, 264V, 265D, 266A, 267G, 268L, 269W
CDD
cd05369 (TER_DECR_SDR_a)

144K

homotetramer interface
88M, 119N, 120F, 121A, 123L, 124S, 125S, 128F, 129R, 132V, 136L, 137I, 140Y, 141N, 144K, 148D, 151K, 164L, 168G, 169T, 170P, 171L, 173T, 176A, 177A, 180A, 181G, 184A, 185L, 187N, 188N, 189L, 190A, 191I, 192E, 193L, 194G, 196L, 207A, 231I, 232P, 233L, 235R, 236M, 237G, 241D, 244D, 245G, 248F, 253A, 255S, 256Y, 257V, 258S, 259G, 260T, 262L, 263V, 264V, 265D, 266A, 267G, 268L, 269W
CDD
cd05369 (TER_DECR_SDR_a)

148D

homotetramer interface
88M, 119N, 120F, 121A, 123L, 124S, 125S, 128F, 129R, 132V, 136L, 137I, 140Y, 141N, 144K, 148D, 151K, 164L, 168G, 169T, 170P, 171L, 173T, 176A, 177A, 180A, 181G, 184A, 185L, 187N, 188N, 189L, 190A, 191I, 192E, 193L, 194G, 196L, 207A, 231I, 232P, 233L, 235R, 236M, 237G, 241D, 244D, 245G, 248F, 253A, 255S, 256Y, 257V, 258S, 259G, 260T, 262L, 263V, 264V, 265D, 266A, 267G, 268L, 269W
CDD
cd05369 (TER_DECR_SDR_a)

151K

homotetramer interface
88M, 119N, 120F, 121A, 123L, 124S, 125S, 128F, 129R, 132V, 136L, 137I, 140Y, 141N, 144K, 148D, 151K, 164L, 168G, 169T, 170P, 171L, 173T, 176A, 177A, 180A, 181G, 184A, 185L, 187N, 188N, 189L, 190A, 191I, 192E, 193L, 194G, 196L, 207A, 231I, 232P, 233L, 235R, 236M, 237G, 241D, 244D, 245G, 248F, 253A, 255S, 256Y, 257V, 258S, 259G, 260T, 262L, 263V, 264V, 265D, 266A, 267G, 268L, 269W
CDD
cd05369 (TER_DECR_SDR_a)

164L

homotetramer interface
88M, 119N, 120F, 121A, 123L, 124S, 125S, 128F, 129R, 132V, 136L, 137I, 140Y, 141N, 144K, 148D, 151K, 164L, 168G, 169T, 170P, 171L, 173T, 176A, 177A, 180A, 181G, 184A, 185L, 187N, 188N, 189L, 190A, 191I, 192E, 193L, 194G, 196L, 207A, 231I, 232P, 233L, 235R, 236M, 237G, 241D, 244D, 245G, 248F, 253A, 255S, 256Y, 257V, 258S, 259G, 260T, 262L, 263V, 264V, 265D, 266A, 267G, 268L, 269W
CDD
cd05369 (TER_DECR_SDR_a)

168G

homotetramer interface
88M, 119N, 120F, 121A, 123L, 124S, 125S, 128F, 129R, 132V, 136L, 137I, 140Y, 141N, 144K, 148D, 151K, 164L, 168G, 169T, 170P, 171L, 173T, 176A, 177A, 180A, 181G, 184A, 185L, 187N, 188N, 189L, 190A, 191I, 192E, 193L, 194G, 196L, 207A, 231I, 232P, 233L, 235R, 236M, 237G, 241D, 244D, 245G, 248F, 253A, 255S, 256Y, 257V, 258S, 259G, 260T, 262L, 263V, 264V, 265D, 266A, 267G, 268L, 269W
CDD
cd05369 (TER_DECR_SDR_a)

169T

homotetramer interface
88M, 119N, 120F, 121A, 123L, 124S, 125S, 128F, 129R, 132V, 136L, 137I, 140Y, 141N, 144K, 148D, 151K, 164L, 168G, 169T, 170P, 171L, 173T, 176A, 177A, 180A, 181G, 184A, 185L, 187N, 188N, 189L, 190A, 191I, 192E, 193L, 194G, 196L, 207A, 231I, 232P, 233L, 235R, 236M, 237G, 241D, 244D, 245G, 248F, 253A, 255S, 256Y, 257V, 258S, 259G, 260T, 262L, 263V, 264V, 265D, 266A, 267G, 268L, 269W
CDD
cd05369 (TER_DECR_SDR_a)

170P

homotetramer interface
88M, 119N, 120F, 121A, 123L, 124S, 125S, 128F, 129R, 132V, 136L, 137I, 140Y, 141N, 144K, 148D, 151K, 164L, 168G, 169T, 170P, 171L, 173T, 176A, 177A, 180A, 181G, 184A, 185L, 187N, 188N, 189L, 190A, 191I, 192E, 193L, 194G, 196L, 207A, 231I, 232P, 233L, 235R, 236M, 237G, 241D, 244D, 245G, 248F, 253A, 255S, 256Y, 257V, 258S, 259G, 260T, 262L, 263V, 264V, 265D, 266A, 267G, 268L, 269W
CDD
cd05369 (TER_DECR_SDR_a)

171L

homotetramer interface
88M, 119N, 120F, 121A, 123L, 124S, 125S, 128F, 129R, 132V, 136L, 137I, 140Y, 141N, 144K, 148D, 151K, 164L, 168G, 169T, 170P, 171L, 173T, 176A, 177A, 180A, 181G, 184A, 185L, 187N, 188N, 189L, 190A, 191I, 192E, 193L, 194G, 196L, 207A, 231I, 232P, 233L, 235R, 236M, 237G, 241D, 244D, 245G, 248F, 253A, 255S, 256Y, 257V, 258S, 259G, 260T, 262L, 263V, 264V, 265D, 266A, 267G, 268L, 269W
CDD
cd05369 (TER_DECR_SDR_a)

173T

homotetramer interface
88M, 119N, 120F, 121A, 123L, 124S, 125S, 128F, 129R, 132V, 136L, 137I, 140Y, 141N, 144K, 148D, 151K, 164L, 168G, 169T, 170P, 171L, 173T, 176A, 177A, 180A, 181G, 184A, 185L, 187N, 188N, 189L, 190A, 191I, 192E, 193L, 194G, 196L, 207A, 231I, 232P, 233L, 235R, 236M, 237G, 241D, 244D, 245G, 248F, 253A, 255S, 256Y, 257V, 258S, 259G, 260T, 262L, 263V, 264V, 265D, 266A, 267G, 268L, 269W
CDD
cd05369 (TER_DECR_SDR_a)

176A

homotetramer interface
88M, 119N, 120F, 121A, 123L, 124S, 125S, 128F, 129R, 132V, 136L, 137I, 140Y, 141N, 144K, 148D, 151K, 164L, 168G, 169T, 170P, 171L, 173T, 176A, 177A, 180A, 181G, 184A, 185L, 187N, 188N, 189L, 190A, 191I, 192E, 193L, 194G, 196L, 207A, 231I, 232P, 233L, 235R, 236M, 237G, 241D, 244D, 245G, 248F, 253A, 255S, 256Y, 257V, 258S, 259G, 260T, 262L, 263V, 264V, 265D, 266A, 267G, 268L, 269W
CDD
cd05369 (TER_DECR_SDR_a)

177A

homotetramer interface
88M, 119N, 120F, 121A, 123L, 124S, 125S, 128F, 129R, 132V, 136L, 137I, 140Y, 141N, 144K, 148D, 151K, 164L, 168G, 169T, 170P, 171L, 173T, 176A, 177A, 180A, 181G, 184A, 185L, 187N, 188N, 189L, 190A, 191I, 192E, 193L, 194G, 196L, 207A, 231I, 232P, 233L, 235R, 236M, 237G, 241D, 244D, 245G, 248F, 253A, 255S, 256Y, 257V, 258S, 259G, 260T, 262L, 263V, 264V, 265D, 266A, 267G, 268L, 269W
CDD
cd05369 (TER_DECR_SDR_a)

180A

homotetramer interface
88M, 119N, 120F, 121A, 123L, 124S, 125S, 128F, 129R, 132V, 136L, 137I, 140Y, 141N, 144K, 148D, 151K, 164L, 168G, 169T, 170P, 171L, 173T, 176A, 177A, 180A, 181G, 184A, 185L, 187N, 188N, 189L, 190A, 191I, 192E, 193L, 194G, 196L, 207A, 231I, 232P, 233L, 235R, 236M, 237G, 241D, 244D, 245G, 248F, 253A, 255S, 256Y, 257V, 258S, 259G, 260T, 262L, 263V, 264V, 265D, 266A, 267G, 268L, 269W
CDD
cd05369 (TER_DECR_SDR_a)

181G

homotetramer interface
88M, 119N, 120F, 121A, 123L, 124S, 125S, 128F, 129R, 132V, 136L, 137I, 140Y, 141N, 144K, 148D, 151K, 164L, 168G, 169T, 170P, 171L, 173T, 176A, 177A, 180A, 181G, 184A, 185L, 187N, 188N, 189L, 190A, 191I, 192E, 193L, 194G, 196L, 207A, 231I, 232P, 233L, 235R, 236M, 237G, 241D, 244D, 245G, 248F, 253A, 255S, 256Y, 257V, 258S, 259G, 260T, 262L, 263V, 264V, 265D, 266A, 267G, 268L, 269W
CDD
cd05369 (TER_DECR_SDR_a)

184A

homotetramer interface
88M, 119N, 120F, 121A, 123L, 124S, 125S, 128F, 129R, 132V, 136L, 137I, 140Y, 141N, 144K, 148D, 151K, 164L, 168G, 169T, 170P, 171L, 173T, 176A, 177A, 180A, 181G, 184A, 185L, 187N, 188N, 189L, 190A, 191I, 192E, 193L, 194G, 196L, 207A, 231I, 232P, 233L, 235R, 236M, 237G, 241D, 244D, 245G, 248F, 253A, 255S, 256Y, 257V, 258S, 259G, 260T, 262L, 263V, 264V, 265D, 266A, 267G, 268L, 269W
CDD
cd05369 (TER_DECR_SDR_a)

185L

homotetramer interface
88M, 119N, 120F, 121A, 123L, 124S, 125S, 128F, 129R, 132V, 136L, 137I, 140Y, 141N, 144K, 148D, 151K, 164L, 168G, 169T, 170P, 171L, 173T, 176A, 177A, 180A, 181G, 184A, 185L, 187N, 188N, 189L, 190A, 191I, 192E, 193L, 194G, 196L, 207A, 231I, 232P, 233L, 235R, 236M, 237G, 241D, 244D, 245G, 248F, 253A, 255S, 256Y, 257V, 258S, 259G, 260T, 262L, 263V, 264V, 265D, 266A, 267G, 268L, 269W
CDD
cd05369 (TER_DECR_SDR_a)

187N

homotetramer interface
88M, 119N, 120F, 121A, 123L, 124S, 125S, 128F, 129R, 132V, 136L, 137I, 140Y, 141N, 144K, 148D, 151K, 164L, 168G, 169T, 170P, 171L, 173T, 176A, 177A, 180A, 181G, 184A, 185L, 187N, 188N, 189L, 190A, 191I, 192E, 193L, 194G, 196L, 207A, 231I, 232P, 233L, 235R, 236M, 237G, 241D, 244D, 245G, 248F, 253A, 255S, 256Y, 257V, 258S, 259G, 260T, 262L, 263V, 264V, 265D, 266A, 267G, 268L, 269W
CDD
cd05369 (TER_DECR_SDR_a)

188N

homotetramer interface
88M, 119N, 120F, 121A, 123L, 124S, 125S, 128F, 129R, 132V, 136L, 137I, 140Y, 141N, 144K, 148D, 151K, 164L, 168G, 169T, 170P, 171L, 173T, 176A, 177A, 180A, 181G, 184A, 185L, 187N, 188N, 189L, 190A, 191I, 192E, 193L, 194G, 196L, 207A, 231I, 232P, 233L, 235R, 236M, 237G, 241D, 244D, 245G, 248F, 253A, 255S, 256Y, 257V, 258S, 259G, 260T, 262L, 263V, 264V, 265D, 266A, 267G, 268L, 269W
CDD
cd05369 (TER_DECR_SDR_a)

189L

homotetramer interface
88M, 119N, 120F, 121A, 123L, 124S, 125S, 128F, 129R, 132V, 136L, 137I, 140Y, 141N, 144K, 148D, 151K, 164L, 168G, 169T, 170P, 171L, 173T, 176A, 177A, 180A, 181G, 184A, 185L, 187N, 188N, 189L, 190A, 191I, 192E, 193L, 194G, 196L, 207A, 231I, 232P, 233L, 235R, 236M, 237G, 241D, 244D, 245G, 248F, 253A, 255S, 256Y, 257V, 258S, 259G, 260T, 262L, 263V, 264V, 265D, 266A, 267G, 268L, 269W
CDD
cd05369 (TER_DECR_SDR_a)

190A

homotetramer interface
88M, 119N, 120F, 121A, 123L, 124S, 125S, 128F, 129R, 132V, 136L, 137I, 140Y, 141N, 144K, 148D, 151K, 164L, 168G, 169T, 170P, 171L, 173T, 176A, 177A, 180A, 181G, 184A, 185L, 187N, 188N, 189L, 190A, 191I, 192E, 193L, 194G, 196L, 207A, 231I, 232P, 233L, 235R, 236M, 237G, 241D, 244D, 245G, 248F, 253A, 255S, 256Y, 257V, 258S, 259G, 260T, 262L, 263V, 264V, 265D, 266A, 267G, 268L, 269W
CDD
cd05369 (TER_DECR_SDR_a)

191I

homotetramer interface
88M, 119N, 120F, 121A, 123L, 124S, 125S, 128F, 129R, 132V, 136L, 137I, 140Y, 141N, 144K, 148D, 151K, 164L, 168G, 169T, 170P, 171L, 173T, 176A, 177A, 180A, 181G, 184A, 185L, 187N, 188N, 189L, 190A, 191I, 192E, 193L, 194G, 196L, 207A, 231I, 232P, 233L, 235R, 236M, 237G, 241D, 244D, 245G, 248F, 253A, 255S, 256Y, 257V, 258S, 259G, 260T, 262L, 263V, 264V, 265D, 266A, 267G, 268L, 269W
CDD
cd05369 (TER_DECR_SDR_a)

192E

homotetramer interface
88M, 119N, 120F, 121A, 123L, 124S, 125S, 128F, 129R, 132V, 136L, 137I, 140Y, 141N, 144K, 148D, 151K, 164L, 168G, 169T, 170P, 171L, 173T, 176A, 177A, 180A, 181G, 184A, 185L, 187N, 188N, 189L, 190A, 191I, 192E, 193L, 194G, 196L, 207A, 231I, 232P, 233L, 235R, 236M, 237G, 241D, 244D, 245G, 248F, 253A, 255S, 256Y, 257V, 258S, 259G, 260T, 262L, 263V, 264V, 265D, 266A, 267G, 268L, 269W
CDD
cd05369 (TER_DECR_SDR_a)

193L

homotetramer interface
88M, 119N, 120F, 121A, 123L, 124S, 125S, 128F, 129R, 132V, 136L, 137I, 140Y, 141N, 144K, 148D, 151K, 164L, 168G, 169T, 170P, 171L, 173T, 176A, 177A, 180A, 181G, 184A, 185L, 187N, 188N, 189L, 190A, 191I, 192E, 193L, 194G, 196L, 207A, 231I, 232P, 233L, 235R, 236M, 237G, 241D, 244D, 245G, 248F, 253A, 255S, 256Y, 257V, 258S, 259G, 260T, 262L, 263V, 264V, 265D, 266A, 267G, 268L, 269W
CDD
cd05369 (TER_DECR_SDR_a)

194G

homotetramer interface
88M, 119N, 120F, 121A, 123L, 124S, 125S, 128F, 129R, 132V, 136L, 137I, 140Y, 141N, 144K, 148D, 151K, 164L, 168G, 169T, 170P, 171L, 173T, 176A, 177A, 180A, 181G, 184A, 185L, 187N, 188N, 189L, 190A, 191I, 192E, 193L, 194G, 196L, 207A, 231I, 232P, 233L, 235R, 236M, 237G, 241D, 244D, 245G, 248F, 253A, 255S, 256Y, 257V, 258S, 259G, 260T, 262L, 263V, 264V, 265D, 266A, 267G, 268L, 269W
CDD
cd05369 (TER_DECR_SDR_a)

196L

homotetramer interface
88M, 119N, 120F, 121A, 123L, 124S, 125S, 128F, 129R, 132V, 136L, 137I, 140Y, 141N, 144K, 148D, 151K, 164L, 168G, 169T, 170P, 171L, 173T, 176A, 177A, 180A, 181G, 184A, 185L, 187N, 188N, 189L, 190A, 191I, 192E, 193L, 194G, 196L, 207A, 231I, 232P, 233L, 235R, 236M, 237G, 241D, 244D, 245G, 248F, 253A, 255S, 256Y, 257V, 258S, 259G, 260T, 262L, 263V, 264V, 265D, 266A, 267G, 268L, 269W
CDD
cd05369 (TER_DECR_SDR_a)

207A

homotetramer interface
88M, 119N, 120F, 121A, 123L, 124S, 125S, 128F, 129R, 132V, 136L, 137I, 140Y, 141N, 144K, 148D, 151K, 164L, 168G, 169T, 170P, 171L, 173T, 176A, 177A, 180A, 181G, 184A, 185L, 187N, 188N, 189L, 190A, 191I, 192E, 193L, 194G, 196L, 207A, 231I, 232P, 233L, 235R, 236M, 237G, 241D, 244D, 245G, 248F, 253A, 255S, 256Y, 257V, 258S, 259G, 260T, 262L, 263V, 264V, 265D, 266A, 267G, 268L, 269W
CDD
cd05369 (TER_DECR_SDR_a)

231I

homotetramer interface
88M, 119N, 120F, 121A, 123L, 124S, 125S, 128F, 129R, 132V, 136L, 137I, 140Y, 141N, 144K, 148D, 151K, 164L, 168G, 169T, 170P, 171L, 173T, 176A, 177A, 180A, 181G, 184A, 185L, 187N, 188N, 189L, 190A, 191I, 192E, 193L, 194G, 196L, 207A, 231I, 232P, 233L, 235R, 236M, 237G, 241D, 244D, 245G, 248F, 253A, 255S, 256Y, 257V, 258S, 259G, 260T, 262L, 263V, 264V, 265D, 266A, 267G, 268L, 269W
CDD
cd05369 (TER_DECR_SDR_a)

232P

homotetramer interface
88M, 119N, 120F, 121A, 123L, 124S, 125S, 128F, 129R, 132V, 136L, 137I, 140Y, 141N, 144K, 148D, 151K, 164L, 168G, 169T, 170P, 171L, 173T, 176A, 177A, 180A, 181G, 184A, 185L, 187N, 188N, 189L, 190A, 191I, 192E, 193L, 194G, 196L, 207A, 231I, 232P, 233L, 235R, 236M, 237G, 241D, 244D, 245G, 248F, 253A, 255S, 256Y, 257V, 258S, 259G, 260T, 262L, 263V, 264V, 265D, 266A, 267G, 268L, 269W
CDD
cd05369 (TER_DECR_SDR_a)

233L

homotetramer interface
88M, 119N, 120F, 121A, 123L, 124S, 125S, 128F, 129R, 132V, 136L, 137I, 140Y, 141N, 144K, 148D, 151K, 164L, 168G, 169T, 170P, 171L, 173T, 176A, 177A, 180A, 181G, 184A, 185L, 187N, 188N, 189L, 190A, 191I, 192E, 193L, 194G, 196L, 207A, 231I, 232P, 233L, 235R, 236M, 237G, 241D, 244D, 245G, 248F, 253A, 255S, 256Y, 257V, 258S, 259G, 260T, 262L, 263V, 264V, 265D, 266A, 267G, 268L, 269W
CDD
cd05369 (TER_DECR_SDR_a)

235R

homotetramer interface
88M, 119N, 120F, 121A, 123L, 124S, 125S, 128F, 129R, 132V, 136L, 137I, 140Y, 141N, 144K, 148D, 151K, 164L, 168G, 169T, 170P, 171L, 173T, 176A, 177A, 180A, 181G, 184A, 185L, 187N, 188N, 189L, 190A, 191I, 192E, 193L, 194G, 196L, 207A, 231I, 232P, 233L, 235R, 236M, 237G, 241D, 244D, 245G, 248F, 253A, 255S, 256Y, 257V, 258S, 259G, 260T, 262L, 263V, 264V, 265D, 266A, 267G, 268L, 269W
CDD
cd05369 (TER_DECR_SDR_a)

236M

homotetramer interface
88M, 119N, 120F, 121A, 123L, 124S, 125S, 128F, 129R, 132V, 136L, 137I, 140Y, 141N, 144K, 148D, 151K, 164L, 168G, 169T, 170P, 171L, 173T, 176A, 177A, 180A, 181G, 184A, 185L, 187N, 188N, 189L, 190A, 191I, 192E, 193L, 194G, 196L, 207A, 231I, 232P, 233L, 235R, 236M, 237G, 241D, 244D, 245G, 248F, 253A, 255S, 256Y, 257V, 258S, 259G, 260T, 262L, 263V, 264V, 265D, 266A, 267G, 268L, 269W
CDD
cd05369 (TER_DECR_SDR_a)

237G

homotetramer interface
88M, 119N, 120F, 121A, 123L, 124S, 125S, 128F, 129R, 132V, 136L, 137I, 140Y, 141N, 144K, 148D, 151K, 164L, 168G, 169T, 170P, 171L, 173T, 176A, 177A, 180A, 181G, 184A, 185L, 187N, 188N, 189L, 190A, 191I, 192E, 193L, 194G, 196L, 207A, 231I, 232P, 233L, 235R, 236M, 237G, 241D, 244D, 245G, 248F, 253A, 255S, 256Y, 257V, 258S, 259G, 260T, 262L, 263V, 264V, 265D, 266A, 267G, 268L, 269W
CDD
cd05369 (TER_DECR_SDR_a)

241D

homotetramer interface
88M, 119N, 120F, 121A, 123L, 124S, 125S, 128F, 129R, 132V, 136L, 137I, 140Y, 141N, 144K, 148D, 151K, 164L, 168G, 169T, 170P, 171L, 173T, 176A, 177A, 180A, 181G, 184A, 185L, 187N, 188N, 189L, 190A, 191I, 192E, 193L, 194G, 196L, 207A, 231I, 232P, 233L, 235R, 236M, 237G, 241D, 244D, 245G, 248F, 253A, 255S, 256Y, 257V, 258S, 259G, 260T, 262L, 263V, 264V, 265D, 266A, 267G, 268L, 269W
CDD
cd05369 (TER_DECR_SDR_a)

244D

homotetramer interface
88M, 119N, 120F, 121A, 123L, 124S, 125S, 128F, 129R, 132V, 136L, 137I, 140Y, 141N, 144K, 148D, 151K, 164L, 168G, 169T, 170P, 171L, 173T, 176A, 177A, 180A, 181G, 184A, 185L, 187N, 188N, 189L, 190A, 191I, 192E, 193L, 194G, 196L, 207A, 231I, 232P, 233L, 235R, 236M, 237G, 241D, 244D, 245G, 248F, 253A, 255S, 256Y, 257V, 258S, 259G, 260T, 262L, 263V, 264V, 265D, 266A, 267G, 268L, 269W
CDD
cd05369 (TER_DECR_SDR_a)

245G

homotetramer interface
88M, 119N, 120F, 121A, 123L, 124S, 125S, 128F, 129R, 132V, 136L, 137I, 140Y, 141N, 144K, 148D, 151K, 164L, 168G, 169T, 170P, 171L, 173T, 176A, 177A, 180A, 181G, 184A, 185L, 187N, 188N, 189L, 190A, 191I, 192E, 193L, 194G, 196L, 207A, 231I, 232P, 233L, 235R, 236M, 237G, 241D, 244D, 245G, 248F, 253A, 255S, 256Y, 257V, 258S, 259G, 260T, 262L, 263V, 264V, 265D, 266A, 267G, 268L, 269W
CDD
cd05369 (TER_DECR_SDR_a)

248F

homotetramer interface
88M, 119N, 120F, 121A, 123L, 124S, 125S, 128F, 129R, 132V, 136L, 137I, 140Y, 141N, 144K, 148D, 151K, 164L, 168G, 169T, 170P, 171L, 173T, 176A, 177A, 180A, 181G, 184A, 185L, 187N, 188N, 189L, 190A, 191I, 192E, 193L, 194G, 196L, 207A, 231I, 232P, 233L, 235R, 236M, 237G, 241D, 244D, 245G, 248F, 253A, 255S, 256Y, 257V, 258S, 259G, 260T, 262L, 263V, 264V, 265D, 266A, 267G, 268L, 269W
CDD
cd05369 (TER_DECR_SDR_a)

253A

homotetramer interface
88M, 119N, 120F, 121A, 123L, 124S, 125S, 128F, 129R, 132V, 136L, 137I, 140Y, 141N, 144K, 148D, 151K, 164L, 168G, 169T, 170P, 171L, 173T, 176A, 177A, 180A, 181G, 184A, 185L, 187N, 188N, 189L, 190A, 191I, 192E, 193L, 194G, 196L, 207A, 231I, 232P, 233L, 235R, 236M, 237G, 241D, 244D, 245G, 248F, 253A, 255S, 256Y, 257V, 258S, 259G, 260T, 262L, 263V, 264V, 265D, 266A, 267G, 268L, 269W
CDD
cd05369 (TER_DECR_SDR_a)

255S

homotetramer interface
88M, 119N, 120F, 121A, 123L, 124S, 125S, 128F, 129R, 132V, 136L, 137I, 140Y, 141N, 144K, 148D, 151K, 164L, 168G, 169T, 170P, 171L, 173T, 176A, 177A, 180A, 181G, 184A, 185L, 187N, 188N, 189L, 190A, 191I, 192E, 193L, 194G, 196L, 207A, 231I, 232P, 233L, 235R, 236M, 237G, 241D, 244D, 245G, 248F, 253A, 255S, 256Y, 257V, 258S, 259G, 260T, 262L, 263V, 264V, 265D, 266A, 267G, 268L, 269W
CDD
cd05369 (TER_DECR_SDR_a)

256Y

homotetramer interface
88M, 119N, 120F, 121A, 123L, 124S, 125S, 128F, 129R, 132V, 136L, 137I, 140Y, 141N, 144K, 148D, 151K, 164L, 168G, 169T, 170P, 171L, 173T, 176A, 177A, 180A, 181G, 184A, 185L, 187N, 188N, 189L, 190A, 191I, 192E, 193L, 194G, 196L, 207A, 231I, 232P, 233L, 235R, 236M, 237G, 241D, 244D, 245G, 248F, 253A, 255S, 256Y, 257V, 258S, 259G, 260T, 262L, 263V, 264V, 265D, 266A, 267G, 268L, 269W
CDD
cd05369 (TER_DECR_SDR_a)

257V

homotetramer interface
88M, 119N, 120F, 121A, 123L, 124S, 125S, 128F, 129R, 132V, 136L, 137I, 140Y, 141N, 144K, 148D, 151K, 164L, 168G, 169T, 170P, 171L, 173T, 176A, 177A, 180A, 181G, 184A, 185L, 187N, 188N, 189L, 190A, 191I, 192E, 193L, 194G, 196L, 207A, 231I, 232P, 233L, 235R, 236M, 237G, 241D, 244D, 245G, 248F, 253A, 255S, 256Y, 257V, 258S, 259G, 260T, 262L, 263V, 264V, 265D, 266A, 267G, 268L, 269W
CDD
cd05369 (TER_DECR_SDR_a)

258S

homotetramer interface
88M, 119N, 120F, 121A, 123L, 124S, 125S, 128F, 129R, 132V, 136L, 137I, 140Y, 141N, 144K, 148D, 151K, 164L, 168G, 169T, 170P, 171L, 173T, 176A, 177A, 180A, 181G, 184A, 185L, 187N, 188N, 189L, 190A, 191I, 192E, 193L, 194G, 196L, 207A, 231I, 232P, 233L, 235R, 236M, 237G, 241D, 244D, 245G, 248F, 253A, 255S, 256Y, 257V, 258S, 259G, 260T, 262L, 263V, 264V, 265D, 266A, 267G, 268L, 269W
CDD
cd05369 (TER_DECR_SDR_a)

259G

homotetramer interface
88M, 119N, 120F, 121A, 123L, 124S, 125S, 128F, 129R, 132V, 136L, 137I, 140Y, 141N, 144K, 148D, 151K, 164L, 168G, 169T, 170P, 171L, 173T, 176A, 177A, 180A, 181G, 184A, 185L, 187N, 188N, 189L, 190A, 191I, 192E, 193L, 194G, 196L, 207A, 231I, 232P, 233L, 235R, 236M, 237G, 241D, 244D, 245G, 248F, 253A, 255S, 256Y, 257V, 258S, 259G, 260T, 262L, 263V, 264V, 265D, 266A, 267G, 268L, 269W
CDD
cd05369 (TER_DECR_SDR_a)

260T

homotetramer interface
88M, 119N, 120F, 121A, 123L, 124S, 125S, 128F, 129R, 132V, 136L, 137I, 140Y, 141N, 144K, 148D, 151K, 164L, 168G, 169T, 170P, 171L, 173T, 176A, 177A, 180A, 181G, 184A, 185L, 187N, 188N, 189L, 190A, 191I, 192E, 193L, 194G, 196L, 207A, 231I, 232P, 233L, 235R, 236M, 237G, 241D, 244D, 245G, 248F, 253A, 255S, 256Y, 257V, 258S, 259G, 260T, 262L, 263V, 264V, 265D, 266A, 267G, 268L, 269W
CDD
cd05369 (TER_DECR_SDR_a)

262L

homotetramer interface
88M, 119N, 120F, 121A, 123L, 124S, 125S, 128F, 129R, 132V, 136L, 137I, 140Y, 141N, 144K, 148D, 151K, 164L, 168G, 169T, 170P, 171L, 173T, 176A, 177A, 180A, 181G, 184A, 185L, 187N, 188N, 189L, 190A, 191I, 192E, 193L, 194G, 196L, 207A, 231I, 232P, 233L, 235R, 236M, 237G, 241D, 244D, 245G, 248F, 253A, 255S, 256Y, 257V, 258S, 259G, 260T, 262L, 263V, 264V, 265D, 266A, 267G, 268L, 269W
CDD
cd05369 (TER_DECR_SDR_a)

263V

homotetramer interface
88M, 119N, 120F, 121A, 123L, 124S, 125S, 128F, 129R, 132V, 136L, 137I, 140Y, 141N, 144K, 148D, 151K, 164L, 168G, 169T, 170P, 171L, 173T, 176A, 177A, 180A, 181G, 184A, 185L, 187N, 188N, 189L, 190A, 191I, 192E, 193L, 194G, 196L, 207A, 231I, 232P, 233L, 235R, 236M, 237G, 241D, 244D, 245G, 248F, 253A, 255S, 256Y, 257V, 258S, 259G, 260T, 262L, 263V, 264V, 265D, 266A, 267G, 268L, 269W
CDD
cd05369 (TER_DECR_SDR_a)

264V

homotetramer interface
88M, 119N, 120F, 121A, 123L, 124S, 125S, 128F, 129R, 132V, 136L, 137I, 140Y, 141N, 144K, 148D, 151K, 164L, 168G, 169T, 170P, 171L, 173T, 176A, 177A, 180A, 181G, 184A, 185L, 187N, 188N, 189L, 190A, 191I, 192E, 193L, 194G, 196L, 207A, 231I, 232P, 233L, 235R, 236M, 237G, 241D, 244D, 245G, 248F, 253A, 255S, 256Y, 257V, 258S, 259G, 260T, 262L, 263V, 264V, 265D, 266A, 267G, 268L, 269W
CDD
cd05369 (TER_DECR_SDR_a)

265D

homotetramer interface
88M, 119N, 120F, 121A, 123L, 124S, 125S, 128F, 129R, 132V, 136L, 137I, 140Y, 141N, 144K, 148D, 151K, 164L, 168G, 169T, 170P, 171L, 173T, 176A, 177A, 180A, 181G, 184A, 185L, 187N, 188N, 189L, 190A, 191I, 192E, 193L, 194G, 196L, 207A, 231I, 232P, 233L, 235R, 236M, 237G, 241D, 244D, 245G, 248F, 253A, 255S, 256Y, 257V, 258S, 259G, 260T, 262L, 263V, 264V, 265D, 266A, 267G, 268L, 269W
CDD
cd05369 (TER_DECR_SDR_a)

266A

homotetramer interface
88M, 119N, 120F, 121A, 123L, 124S, 125S, 128F, 129R, 132V, 136L, 137I, 140Y, 141N, 144K, 148D, 151K, 164L, 168G, 169T, 170P, 171L, 173T, 176A, 177A, 180A, 181G, 184A, 185L, 187N, 188N, 189L, 190A, 191I, 192E, 193L, 194G, 196L, 207A, 231I, 232P, 233L, 235R, 236M, 237G, 241D, 244D, 245G, 248F, 253A, 255S, 256Y, 257V, 258S, 259G, 260T, 262L, 263V, 264V, 265D, 266A, 267G, 268L, 269W
CDD
cd05369 (TER_DECR_SDR_a)

267G

homotetramer interface
88M, 119N, 120F, 121A, 123L, 124S, 125S, 128F, 129R, 132V, 136L, 137I, 140Y, 141N, 144K, 148D, 151K, 164L, 168G, 169T, 170P, 171L, 173T, 176A, 177A, 180A, 181G, 184A, 185L, 187N, 188N, 189L, 190A, 191I, 192E, 193L, 194G, 196L, 207A, 231I, 232P, 233L, 235R, 236M, 237G, 241D, 244D, 245G, 248F, 253A, 255S, 256Y, 257V, 258S, 259G, 260T, 262L, 263V, 264V, 265D, 266A, 267G, 268L, 269W
CDD
cd05369 (TER_DECR_SDR_a)

268L

homotetramer interface
88M, 119N, 120F, 121A, 123L, 124S, 125S, 128F, 129R, 132V, 136L, 137I, 140Y, 141N, 144K, 148D, 151K, 164L, 168G, 169T, 170P, 171L, 173T, 176A, 177A, 180A, 181G, 184A, 185L, 187N, 188N, 189L, 190A, 191I, 192E, 193L, 194G, 196L, 207A, 231I, 232P, 233L, 235R, 236M, 237G, 241D, 244D, 245G, 248F, 253A, 255S, 256Y, 257V, 258S, 259G, 260T, 262L, 263V, 264V, 265D, 266A, 267G, 268L, 269W
CDD
cd05369 (TER_DECR_SDR_a)

269W

homotetramer interface
88M, 119N, 120F, 121A, 123L, 124S, 125S, 128F, 129R, 132V, 136L, 137I, 140Y, 141N, 144K, 148D, 151K, 164L, 168G, 169T, 170P, 171L, 173T, 176A, 177A, 180A, 181G, 184A, 185L, 187N, 188N, 189L, 190A, 191I, 192E, 193L, 194G, 196L, 207A, 231I, 232P, 233L, 235R, 236M, 237G, 241D, 244D, 245G, 248F, 253A, 255S, 256Y, 257V, 258S, 259G, 260T, 262L, 263V, 264V, 265D, 266A, 267G, 268L, 269W
CDD
cd05369 (TER_DECR_SDR_a)
active site cd05369

115N

active site
115N, 164L, 175A, 179K
CDD
cd05369 (TER_DECR_SDR_a)

164L

active site
115N, 164L, 175A, 179K
CDD
cd05369 (TER_DECR_SDR_a)

175A

active site
115N, 164L, 175A, 179K
CDD
cd05369 (TER_DECR_SDR_a)

179K

active site
115N, 164L, 175A, 179K
CDD
cd05369 (TER_DECR_SDR_a)
homodimer interfac...

119N

homodimer interface
119N, 120F, 121A, 123L, 128F, 129R, 132V, 137I, 140Y, 141N, 168G, 169T, 170P, 171L, 173T, 176A, 177A, 180A, 181G, 184A, 185L, 188N, 191I, 192E
CDD
cd05369 (TER_DECR_SDR_a)

120F

homodimer interface
119N, 120F, 121A, 123L, 128F, 129R, 132V, 137I, 140Y, 141N, 168G, 169T, 170P, 171L, 173T, 176A, 177A, 180A, 181G, 184A, 185L, 188N, 191I, 192E
CDD
cd05369 (TER_DECR_SDR_a)

121A

homodimer interface
119N, 120F, 121A, 123L, 128F, 129R, 132V, 137I, 140Y, 141N, 168G, 169T, 170P, 171L, 173T, 176A, 177A, 180A, 181G, 184A, 185L, 188N, 191I, 192E
CDD
cd05369 (TER_DECR_SDR_a)

123L

homodimer interface
119N, 120F, 121A, 123L, 128F, 129R, 132V, 137I, 140Y, 141N, 168G, 169T, 170P, 171L, 173T, 176A, 177A, 180A, 181G, 184A, 185L, 188N, 191I, 192E
CDD
cd05369 (TER_DECR_SDR_a)

128F

homodimer interface
119N, 120F, 121A, 123L, 128F, 129R, 132V, 137I, 140Y, 141N, 168G, 169T, 170P, 171L, 173T, 176A, 177A, 180A, 181G, 184A, 185L, 188N, 191I, 192E
CDD
cd05369 (TER_DECR_SDR_a)

129R

homodimer interface
119N, 120F, 121A, 123L, 128F, 129R, 132V, 137I, 140Y, 141N, 168G, 169T, 170P, 171L, 173T, 176A, 177A, 180A, 181G, 184A, 185L, 188N, 191I, 192E
CDD
cd05369 (TER_DECR_SDR_a)

132V

homodimer interface
119N, 120F, 121A, 123L, 128F, 129R, 132V, 137I, 140Y, 141N, 168G, 169T, 170P, 171L, 173T, 176A, 177A, 180A, 181G, 184A, 185L, 188N, 191I, 192E
CDD
cd05369 (TER_DECR_SDR_a)

137I

homodimer interface
119N, 120F, 121A, 123L, 128F, 129R, 132V, 137I, 140Y, 141N, 168G, 169T, 170P, 171L, 173T, 176A, 177A, 180A, 181G, 184A, 185L, 188N, 191I, 192E
CDD
cd05369 (TER_DECR_SDR_a)

140Y

homodimer interface
119N, 120F, 121A, 123L, 128F, 129R, 132V, 137I, 140Y, 141N, 168G, 169T, 170P, 171L, 173T, 176A, 177A, 180A, 181G, 184A, 185L, 188N, 191I, 192E
CDD
cd05369 (TER_DECR_SDR_a)

141N

homodimer interface
119N, 120F, 121A, 123L, 128F, 129R, 132V, 137I, 140Y, 141N, 168G, 169T, 170P, 171L, 173T, 176A, 177A, 180A, 181G, 184A, 185L, 188N, 191I, 192E
CDD
cd05369 (TER_DECR_SDR_a)

168G

homodimer interface
119N, 120F, 121A, 123L, 128F, 129R, 132V, 137I, 140Y, 141N, 168G, 169T, 170P, 171L, 173T, 176A, 177A, 180A, 181G, 184A, 185L, 188N, 191I, 192E
CDD
cd05369 (TER_DECR_SDR_a)

169T

homodimer interface
119N, 120F, 121A, 123L, 128F, 129R, 132V, 137I, 140Y, 141N, 168G, 169T, 170P, 171L, 173T, 176A, 177A, 180A, 181G, 184A, 185L, 188N, 191I, 192E
CDD
cd05369 (TER_DECR_SDR_a)

170P

homodimer interface
119N, 120F, 121A, 123L, 128F, 129R, 132V, 137I, 140Y, 141N, 168G, 169T, 170P, 171L, 173T, 176A, 177A, 180A, 181G, 184A, 185L, 188N, 191I, 192E
CDD
cd05369 (TER_DECR_SDR_a)

171L

homodimer interface
119N, 120F, 121A, 123L, 128F, 129R, 132V, 137I, 140Y, 141N, 168G, 169T, 170P, 171L, 173T, 176A, 177A, 180A, 181G, 184A, 185L, 188N, 191I, 192E
CDD
cd05369 (TER_DECR_SDR_a)

173T

homodimer interface
119N, 120F, 121A, 123L, 128F, 129R, 132V, 137I, 140Y, 141N, 168G, 169T, 170P, 171L, 173T, 176A, 177A, 180A, 181G, 184A, 185L, 188N, 191I, 192E
CDD
cd05369 (TER_DECR_SDR_a)

176A

homodimer interface
119N, 120F, 121A, 123L, 128F, 129R, 132V, 137I, 140Y, 141N, 168G, 169T, 170P, 171L, 173T, 176A, 177A, 180A, 181G, 184A, 185L, 188N, 191I, 192E
CDD
cd05369 (TER_DECR_SDR_a)

177A

homodimer interface
119N, 120F, 121A, 123L, 128F, 129R, 132V, 137I, 140Y, 141N, 168G, 169T, 170P, 171L, 173T, 176A, 177A, 180A, 181G, 184A, 185L, 188N, 191I, 192E
CDD
cd05369 (TER_DECR_SDR_a)

180A

homodimer interface
119N, 120F, 121A, 123L, 128F, 129R, 132V, 137I, 140Y, 141N, 168G, 169T, 170P, 171L, 173T, 176A, 177A, 180A, 181G, 184A, 185L, 188N, 191I, 192E
CDD
cd05369 (TER_DECR_SDR_a)

181G

homodimer interface
119N, 120F, 121A, 123L, 128F, 129R, 132V, 137I, 140Y, 141N, 168G, 169T, 170P, 171L, 173T, 176A, 177A, 180A, 181G, 184A, 185L, 188N, 191I, 192E
CDD
cd05369 (TER_DECR_SDR_a)

184A

homodimer interface
119N, 120F, 121A, 123L, 128F, 129R, 132V, 137I, 140Y, 141N, 168G, 169T, 170P, 171L, 173T, 176A, 177A, 180A, 181G, 184A, 185L, 188N, 191I, 192E
CDD
cd05369 (TER_DECR_SDR_a)

185L

homodimer interface
119N, 120F, 121A, 123L, 128F, 129R, 132V, 137I, 140Y, 141N, 168G, 169T, 170P, 171L, 173T, 176A, 177A, 180A, 181G, 184A, 185L, 188N, 191I, 192E
CDD
cd05369 (TER_DECR_SDR_a)

188N

homodimer interface
119N, 120F, 121A, 123L, 128F, 129R, 132V, 137I, 140Y, 141N, 168G, 169T, 170P, 171L, 173T, 176A, 177A, 180A, 181G, 184A, 185L, 188N, 191I, 192E
CDD
cd05369 (TER_DECR_SDR_a)

191I

homodimer interface
119N, 120F, 121A, 123L, 128F, 129R, 132V, 137I, 140Y, 141N, 168G, 169T, 170P, 171L, 173T, 176A, 177A, 180A, 181G, 184A, 185L, 188N, 191I, 192E
CDD
cd05369 (TER_DECR_SDR_a)

192E

homodimer interface
119N, 120F, 121A, 123L, 128F, 129R, 132V, 137I, 140Y, 141N, 168G, 169T, 170P, 171L, 173T, 176A, 177A, 180A, 181G, 184A, 185L, 188N, 191I, 192E
CDD
cd05369 (TER_DECR_SDR_a)

Protein sequence

>MCA_03583_1
MSSLDQSYVKNSAWKPNLFENKVVFITGGAGTIGKVQSQALVLLGASVSIIGRNKQKTESTAAELSKLIPPGSSAKVIGI
GEVDVRNMATLTAAVERTVKELGKIDYVIAGAAGNFLANFANLSSNAFRTVVEIDLIGSYNTAKATYDQVKANKGAYVFI
SAGLHYAGTPLQTHAAAAKAGVDALSNNLAIELGPLGIRSNVISPGAIEGTEGMDRLAPTSEIAKKTLQYIPLQRMGTPR
DIADGTVFLLSPAASYVSGTTLVVDAGLWRMGNIANDMYPDELTKMNSGKNKL

GO term prediction

Biological Process

None predicted.

Molecular Function

None predicted.

Cellular Component

None predicted.

Filter view on

Entry type

Status

Per-residue features

MCA_03583_1

Protein function

Protein alignments

Mitochondrial localization by mitoprotII

Protein family membership

Domains and repeats

Detailed signature matches

Residue annotation

Protein sequence

GO term prediction

Biological Process

Molecular Function

Cellular Component