Protein

MIA_03264_1

Length
240 amino acids

Browser: contig04:725769-726652+

Protein function

EGGNOG:0PJKFFG09439.1Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX (By similarity)
SGD closest match:S000005144YNL200CNAD(P)H-hydrate epimerase
CGD closest match:CAL0000191549CAALFM_C102220CANAD(P)H-hydrate epimerase

Protein alignments

%idAln lengthE-value
MCA_03490_171.930%2284.00e-108MCA_03490_1
A0A060TD57_BLAAD59.649%2282.75e-86NAD(P)H-hydrate epimerase OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D04598g PE=3 SV=1
UniRef50_W1QA2152.609%2305.97e-71NAD(P)H-hydrate epimerase n=59 Tax=Eukaryota TaxID=2759 RepID=W1QA21_OGAPD
A0A0J9XAM8_GEOCN53.390%2361.58e-73NAD(P)H-hydrate epimerase OS=Geotrichum candidum GN=BN980_GECA07s02925g PE=3 SV=1
NNRE_YARLI51.754%2282.46e-66NAD(P)H-hydrate epimerase OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0B23122g PE=3 SV=1
NNRE_YEAST47.186%2311.17e-60NAD(P)H-hydrate epimerase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YNL200C PE=1 SV=1
A0A1E4TMB5_9ASCO53.234%2011.94e-60Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_30917 PE=4 SV=1
NNRE_CANAL48.291%2341.73e-56NAD(P)H-hydrate epimerase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=CAALFM_C102220CA PE=3 SV=2
A0A1E3PJG1_9ASCO43.478%2533.20e-55NAD(P)H-hydrate epimerase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_70556 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.2369
Predicted cleavage: 14

Protein family membership

None predicted.

Domains and repeats

  1. Domain
1 50 100 150 200 240

Detailed signature matches

  1. Domain IPR004443
    YjeF N-terminal domain
    1. PF03853 (YjeF_N)
    2. G3DSA:3.40.50...
    3. MF_01966 (NADHX_epi...)
    4. SSF64153 (YjeF N-te...)
    5. PS51385 (YJEF_N)
    6. TIGR00197
Unintegrated signatures no IPR
Unintegrated signatures
  1. NON_CYTOPLASM... (N...)
  2. SIGNAL_PEPTIDE (Sig...)
  3. SIGNAL_PEPTID... (S...)
  4. SIGNAL_PEPTID... (S...)
  5. SIGNAL_PEPTID... (S...)

Protein sequence

>MIA_03264_1
MSMRYLSASVAAAVDKELMSTQAFSLDQLMELAGLSVAEAVLKVHPPEKGSKVLVLAGPGNNGGDGLVAARHLSLWGYSL
SYYYPRKSRHEHLVRLETQLKNLGIPEISTAAEVAAALSGPSKVNHVIDALFGFSFKPPMRPPFDEILRLLQENQGAVPI
TAVDIPSSWDVDQGPLEGNTYAPEVLVSLTGPKPAAKFFKGRHFVGGRFISKEFAAKWDFDVPPYKGGEQVVEVTGEEKL

GO term prediction

Biological Process

None predicted.

Molecular Function

None predicted.

Cellular Component

None predicted.